journal
https://read.qxmd.com/read/38754734/the-innate-immune-cells-at-the-heart-of-kidney-allograft-rejection
#1
JOURNAL ARTICLE
Griffith B Perkins, James D Zuiani, P Toby Coates
No abstract text is available yet for this article.
May 14, 2024: Kidney International
https://read.qxmd.com/read/38750901/variant-upon-variant-kidney-disease-risk-associated-with-apol1-g2-genetic-variants-is-abrogated-by-the-apol1-p-n264k-variant
#2
JOURNAL ARTICLE
Sethu M Madhavan, Johannes Schlöndorff
No abstract text is available yet for this article.
May 13, 2024: Kidney International
https://read.qxmd.com/read/38739061/corrigendum-to-kdigo-2024-clinical-practice-guideline-for-the-management-of-antineutrophil-cytoplasmic-antibody-anca-associated-vasculitis-kidney-int-2024-105-3s-s71-s116
#3
(no author information available yet)
No abstract text is available yet for this article.
May 8, 2024: Kidney International
https://read.qxmd.com/read/38739060/corrigendum-to-executive-summary-of-the-kdigo-2024-clinical-practice-guideline-for-the-management-of%C3%A2-anca-associated-vasculitis-kidney-int-2024-105-3-447-449
#4
Jürgen Floege, David R W Jayne, Jan-Stephan F Sanders, Vladimír Tesar, Ethan M Balk, Craig E Gordon, Gaelen Adam, Marcello A Tonelli, Michael Cheung, Amy Earley, Brad H Rovin
No abstract text is available yet for this article.
May 8, 2024: Kidney International
https://read.qxmd.com/read/38723749/monoclonal-immunoglobulin-crystalline-nephropathies
#5
JOURNAL ARTICLE
Samih H Nasr, Christophe Sirac, Nelson Leung, Frank Bridoux
Monoclonal immunoglobulin (MIg) crystalline nephropathies are rare lesions resulting from precipitation of MIgs in the kidney as crystalline inclusions. They can be categorized into lesions with predominant intracellular crystals (light chain [LC] proximal tubulopathy, LC crystal-storing histiocytosis, LC crystalline podocytopathy] and lesions with predominant extracellular crystals (crystalglobulin-induced nephropathy, crystalline variant of LC cast nephropathy). The majority of these lesions are associated with low tumor burden lymphoproliferative disorders, with the exception of crystalline variant of LC cast nephropathy...
May 7, 2024: Kidney International
https://read.qxmd.com/read/38705274/frailty-in-patients-on-dialysis
#6
REVIEW
Gordon Chun-Kau Chan, Kamyar Kalantar-Zadeh, Jack Kit-Chung Ng, Na Tian, Aine Burns, Kai-Ming Chow, Cheuk-Chun Szeto, Philip Kam-Tao Li
Frailty is a condition that is frequently observed among patients performing dialysis. It is characterised by a decline in both physiological and cognitive state, leading to a combination of symptoms such as weight loss, exhaustion, low physical activity, weakness, and slow walking speed. Frail patients not only experience a poor quality of life, but they are also at a higher risk of hospitalization, infection, cardiovascular events, dialysis-associated complications, and death. Frailty occurs as a result of a combination and interaction of various medical issues in patients who are on dialysis...
May 3, 2024: Kidney International
https://read.qxmd.com/read/38697479/long-term-impact-of-immediate-versus-deferred-antiretroviral-therapy-on-kidney-health-in-people-with-hiv
#7
JOURNAL ARTICLE
Annegret Pelchen-Matthews, Amanda Mocroft, Lene Ryom, Michael J Ross, Shweta Sharma, Steven Coca, Amit Achhra, Elaine Cornell, Russell Tracy, Andrew Phillips, Marta Montero Alonso, Giota Toulomi, Brian K Agan, Nicholas Medland, Christina M Wyatt
People with human immunodeficiency virus (HIV) are at risk for chronic kidney disease (CKD) due to HIV and antiretroviral therapy (ART) nephrotoxicity. Immediate ART initiation reduces mortality and is now the standard of care, but the long-term impact of prolonged ART exposure on CKD is unknown. To evaluate this, the Strategic Timing of Antiretroviral Treatment (START) trial randomized 4,684 ART-naïve adults with CD4 cell count under 500 cells/mm3 to immediate versus deferred ART. We previously reported a small but statistically significantly greater decline in estimated glomerular filtration rate (eGFR) over a median of 2...
April 30, 2024: Kidney International
https://read.qxmd.com/read/38697478/podocyte-derived-soluble-rarres1-drives-kidney-disease-progression-through-direct-podocyte-and-proximal-tubular-injury
#8
JOURNAL ARTICLE
Ye Feng, Zeguo Sun, Jia Fu, Fang Zhong, Weijia Zhang, Chengguo Wei, Anqun Chen, Bi-Cheng Liu, John C He, Kyung Lee
Retinoic acid receptor responder protein-1 (RARRES1) is a podocyte-enriched transmembrane protein whose increased expression correlates with human glomerular disease progression. RARRES1 promotes podocytopenia and glomerulosclerosis via p53-mediated podocyte apoptosis. Importantly, the cytopathic actions of RARRES1 are entirely dependent on its proteolytic cleavage into a soluble protein (sRARRES1) and subsequent podocyte uptake by endocytosis, as a cleavage mutant RARRES1 exerted no effects in vitro or in vivo...
April 30, 2024: Kidney International
https://read.qxmd.com/read/38692408/assessment-of-biological-organ-age-using-molecular-pathology-in-pre-transplant-kidney-biopsies
#9
JOURNAL ARTICLE
Roy Zhang, Patrick B Trotter, James McCaffrey, Rory Fitzroy, Giorgio Trivioli, Benjamin J Stewart, John R Ferdinand, Kevin W Loudon, Alexandra Riding, Jonathan West, Ashley Ferro, Menna R Clatworthy
Organ shortage is a major challenge in kidney transplantation but the use of older donors, often with co-morbidities, is hampered by inconsistent outcomes. Methods of accurately stratifying marginal donor organs by clinical and histological assessment are lacking. To better understand organ variability, we profiled the transcriptomes of 271 kidneys from deceased donors at retrieval. Following correction for biopsy composition, we assessed molecular pathways that associated with delayed, and sub-optimal one-year graft function...
April 29, 2024: Kidney International
https://read.qxmd.com/read/38685562/high-dimensional-mass-cytometry-identified-circulating-natural-killer-t-cell-subsets-associated-with-protection-from-cytomegalovirus-infection-in-kidney-transplant-recipients
#10
JOURNAL ARTICLE
Laura Donadeu, Thomas Jouve, Sofia Bin, Susan Hartzell, Elena Crespo, Alba Torija, Marta Jarque, Delphine Kevella, José Zúñiga, Weijia Zhang, Zeguo Sun, Alberto Verlato, Mónica Martínez-Gallo, Cristina Font-Miñarro, Maria Meneghini, Nestor Toapanta, Irina B Torres, Joana Sellarés, Manel Perelló, Hannah Kaminski, Lionel Couzi, Alexandre Loupy, Gaetano La Manna, Francesc Moreso, Paolo Cravedi, Oriol Bestard
Cytomegalovirus (CMV) infection is associated with poor kidney transplant outcomes. While innate and adaptive immune cells have been implicated in its prevention, an in-depth characterization of the in vivo kinetics of multiple cell subsets and their role in protecting against CMV infection has not been achieved. Here, we performed high-dimensional immune phenotyping by mass cytometry, and functional assays, on 112 serially collected samples from CMV seropositive kidney transplant recipients. Advanced unsupervised deep learning analysis was used to assess immune cell populations that significantly correlated with prevention against CMV infection and anti-viral immune function...
April 27, 2024: Kidney International
https://read.qxmd.com/read/38685561/a-cohort-study-of-sodium-glucose-cotransporter-2-inhibitors-after-acute-kidney-injury-among-veterans-with-diabetic-kidney-disease
#11
JOURNAL ARTICLE
Daniel P Murphy, Julian Wolfson, Scott Reule, Kirsten L Johansen, Areef Ishani, Paul E Drawz
Sodium-glucose cotransporter-2 inhibitors (SGLT2i) reduce the risk for several adverse outcomes among patients with diabetic kidney disease. Yet, optimal timing for SGLT2i after acute kidney injury (AKI) is uncertain, as are the providers responsible for post-AKI SGLT2i initiation. Using a retrospective cohort of United States Veterans with diabetes mellitus type 2 and proteinuria, we examined encounters by provider specialty before SGLT2i initiation and subsequent all-cause mortality after hospitalization with AKI, defined by a 50% or more rise in serum creatinine...
April 27, 2024: Kidney International
https://read.qxmd.com/read/38615743/nell-1-associated-membranous-nephropathy-linked-to-skin-fairness-cream-use-insights-from-an-indian-case-series
#12
JOURNAL ARTICLE
Ranjit Narayanan, Sajeesh Sivadas, Anila Abraham Kurien
No abstract text is available yet for this article.
April 12, 2024: Kidney International
https://read.qxmd.com/read/38614389/the-key-role-of-altered-tubule-cell-lipid-metabolism-in-kidney-disease-development
#13
REVIEW
Lauren E Lee, Tomohito Doke, Dhanunjay Mukhi, Katalin Susztak
Kidney epithelial cells have very high energy requirements, which are largely met by fatty acid oxidation. Complex changes in lipid metabolism are observed in patients with kidney disease. Defects in fatty acid oxidation and increased lipid uptake, especially in the context of hyperlipidemia and proteinuria, contribute to this excess lipid build-up and exacerbate kidney disease development. Recent studies have also highlighted the role of increased de novo lipogenesis in kidney fibrosis. The defect in fatty acid oxidation will cause energy starvation...
April 11, 2024: Kidney International
https://read.qxmd.com/read/38775770/unexpected-metabolic-effects-of-sodium-glucose-cotransporter-2-inhibitors
#14
JOURNAL ARTICLE
Tilman B Drueke, Ziad A Massy
No abstract text is available yet for this article.
April 10, 2024: Kidney International
https://read.qxmd.com/read/38647510/deciphering-missense-coding-variants-with-alphamissense
#15
JOURNAL ARTICLE
Zhicheng Pan, Chandra L Theesfeld
No abstract text is available yet for this article.
April 10, 2024: Kidney International
https://read.qxmd.com/read/38626880/implementation-science-a-tool-to-narrow-know-do-gap-and-widen-equity-in-kidney-diseases-and-transplantation
#16
LETTER
Ekamol Tantisattamo
No abstract text is available yet for this article.
April 6, 2024: Kidney International
https://read.qxmd.com/read/38626879/bridging-the-knowledge-practice-gap-in-kidney-care-insights-from-a-medical-student-in-thailand
#17
LETTER
Abhishet Varama
No abstract text is available yet for this article.
April 6, 2024: Kidney International
https://read.qxmd.com/read/38626878/the-authors-reply
#18
LETTER
Winston W S Fung, Valerie A Luyckx, Katherine R Tuttle
No abstract text is available yet for this article.
April 6, 2024: Kidney International
https://read.qxmd.com/read/38626877/the-authors-reply
#19
LETTER
Winston W S Fung, Valerie A Luyckx, Katherine R Tuttle
No abstract text is available yet for this article.
April 6, 2024: Kidney International
https://read.qxmd.com/read/38579988/time-for-action-recognising-chronic-kidney-disease-as-a-major-non-communicable-disease-driver-of-premature-mortality
#20
EDITORIAL
Germaine Wong, Amélie Bernier-Jean, Brad Rovin, Pierre Ronco
No abstract text is available yet for this article.
April 2, 2024: Kidney International
journal
journal
20183
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.