journal

Kidney International

journal
https://read.qxmd.com/read/32204907/the-novel-coronavirus-2019-epidemic-and-kidneys
#1
EDITORIAL
Saraladevi Naicker, Chih-Wei Yang, Shang-Jyh Hwang, Bi-Cheng Liu, Jiang-Hua Chen, Vivekanand Jha
No abstract text is available yet for this article.
March 7, 2020: Kidney International
https://read.qxmd.com/read/32229094/how-to-assess-kidney-function-in-oncology-patients
#2
REVIEW
Jolanta Malyszko, Michael W Lee, Giovambattista Capasso, Pawel Kulicki, Joanna Matuszkiewicz-Rowinska, Pierre Ronco, Paul Stevens, Petra Tesarova, Davide Viggiano, Anna Capasso
Assessment of kidney function in oncology patients is a fundamental factor in profiling the survival risk, determining the appropriate dose of chemotherapeutic drugs, and defining a patient eligibility for clinical trials with novel agents. Both overestimation and underestimation of kidney function may affect the treatment efficacy and outcomes. Overestimation may lead to overdosing or inappropriate agent selection and the corresponding toxicity, whereas underestimation may be responsible for underdosing or inappropriate agent exclusion and subsequent treatment failure...
March 3, 2020: Kidney International
https://read.qxmd.com/read/32059997/renal-tnf%C3%AE-activates-the-wnk-phosphorylation-cascade-and-contributes-to-salt-sensitive-hypertension-in-chronic-kidney-disease
#3
Taisuke Furusho, Eisei Sohara, Shintaro Mandai, Hiroaki Kikuchi, Naohiro Takahashi, Takuya Fujimaru, Hiroko Hashimoto, Yohei Arai, Fumiaki Ando, Moko Zeniya, Takayasu Mori, Koichiro Susa, Kiyoshi Isobe, Naohiro Nomura, Kohei Yamamoto, Tomokazu Okado, Tatemitsu Rai, Shinichi Uchida
The inappropriate over-activation of the with-no-lysine kinase (WNK)-STE20/SPS1-related proline/alanine-rich kinase (SPAK)-sodium chloride cotransporter (NCC) phosphorylation cascade increases sodium reabsorption in distal kidney nephrons, resulting in salt-sensitive hypertension. Although chronic kidney disease (CKD) is a common cause of salt-sensitive hypertension, the involvement of the WNK phosphorylation cascade is unknown. Moreover, the effect of immune systems on WNK kinases has not been investigated despite the fact that immune systems are important for salt sensitivity...
February 8, 2020: Kidney International
https://read.qxmd.com/read/32229096/five-year-kidney-outcomes-of-bariatric-surgery-differ-in-severely-obese-adolescents-and-adults-with-and-without-type-2-diabetes
#4
Petter Bjornstad, Edward Nehus, Todd Jenkins, Mark Mitsnefes, Marva Moxey-Mims, John B Dixon, Thomas H Inge
Bariatric surgery improves markers of kidney health in severe obesity, yet it is unclear if kidney disease outcomes differ according to age at surgery. Therefore, we examined health effects of Roux-en-Y gastric bypass between 161 adolescents and 396 adults participating in two related but distinct studies. Primary outcomes were elevated urine albumin-to-creatinine ratio (UACR) of 30 mg/g or more and hyperfiltration (an estimated glomerular filtration rate of 135 ml/min/1.73m2 or more). Analyses were stratified by the presence of pre-operative type 2 diabetes...
February 3, 2020: Kidney International
https://read.qxmd.com/read/32229095/anti-cd20-mediated-b-cell-depletion-in-autoimmune-diseases-successes-failures-and-future-perspectives
#5
REVIEW
Etienne Crickx, Jean-Claude Weill, Claude-Agnès Reynaud, Matthieu Mahévas
B-cell depletion with anti-CD20 monoclonal antibodies is widely used for the treatment of autoimmune diseases. This review will discuss mechanisms contributing to success or failure of B-cell depletion therapy in antibody-mediated autoimmune diseases. It will also explain how key information about disease pathogeny can be provided by the different outcomes observed after B-cell depletion therapy. These findings provide the basis for future innovative therapeutic strategies aiming at an optimized B cell and/or plasma cell depletion to increase long-term disease remission...
January 30, 2020: Kidney International
https://read.qxmd.com/read/32111372/electronic-health-records-for-the-diagnosis-of-rare-diseases
#6
REVIEW
Nicolas Garcelon, Anita Burgun, Rémi Salomon, Antoine Neuraz
With the emergence of electronic health records, the reuse of clinical data offers new perspectives for the diagnosis and management of patients with rare diseases. However, there are many obstacles to the repurposing of clinical data. The development of decision support systems depends on the ability to recruit patients, extract and integrate the patients' data, mine and stratify these data, and integrate the decision support algorithm into patient care. This last step requires an adaptability of the electronic health records to integrate learning health system tools...
January 14, 2020: Kidney International
https://read.qxmd.com/read/31948598/the-circadian-clock-is-disrupted-in-mice-with-adenine-induced-tubulointerstitial-nephropathy
#7
Hiroaki Motohashi, Yu Tahara, Daniel S Whittaker, Huei-Bin Wang, Takahiro Yamaji, Hiromichi Wakui, Atsushi Haraguchi, Mayu Yamazaki, Hiroki Miyakawa, Koki Hama, Hiroyuki Sasaki, Tomoko Sakai, Rina Hirooka, Kengo Takahashi, Miku Takizawa, Saneyuki Makino, Shinya Aoyama, Christopher S Colwell, Shigenobu Shibata
Chronic Kidney Disease (CKD) is increasing in incidence and has become a worldwide health problem. Sleep disorders are prevalent in patients with CKD raising the possibility that these patients have a disorganized circadian timing system. Here, we examined the effect of adenine-induced tubulointerstitial nephropathy on the circadian system in mice. Compared to controls, adenine-treated mice showed serum biochemistry evidence of CKD as well as increased kidney expression of inflammation and fibrosis markers...
January 9, 2020: Kidney International
https://read.qxmd.com/read/32200873/the-case-a-hidden-deposit
#8
Titi Chen, Nikki Wong, Seethalakshmi Visvanathan, Fiona Kwok, Jai Radhakrishnan, David Harris, Mirna Vucak-Dzumhur
No abstract text is available yet for this article.
April 2020: Kidney International
https://read.qxmd.com/read/32200872/the-case-acute-kidney-injury-after-liver-and-kidney-transplantation
#9
Mattia Rossi, Vincenzo L'Imperio, Jorge Garces, Agnes B Fogo
No abstract text is available yet for this article.
April 2020: Kidney International
https://read.qxmd.com/read/32200871/acquired-thoracic-kidney
#10
Nattawat Klomjit, Ladan Zand
No abstract text is available yet for this article.
April 2020: Kidney International
https://read.qxmd.com/read/32200870/peritoneal-dialysate-tamponading-a-massive-retroperitoneal-hemorrhage
#11
Emily D Gutowski, Maria Clarissa Tio, Ezra A Burch, David E Leaf
No abstract text is available yet for this article.
April 2020: Kidney International
https://read.qxmd.com/read/32200869/corrigendum-to-townsend-rr-guarnieri-p-argyropoulos-c-et-al-on-behalf-of-the-trident-study-investigators-rationale-and-design-of-the-transformative-research-in-diabetic-nephropathy-trident-study-kidney-int-2020-97-10-13
#12
https://read.qxmd.com/read/32200868/corrigendum-to-wang-l-chang-j-h-buckley-af-spurney-rf-knockout-of-trpc6-promotes-insulin-resistance-and-exacerbates-glomerular-injury-in-akita-mice-kidney-int-2019-95-321-332
#13
https://read.qxmd.com/read/32200867/the-authors-reply
#14
LETTER
Ana Malvar, Brad H Rovin
No abstract text is available yet for this article.
April 2020: Kidney International
https://read.qxmd.com/read/32200866/discontinuation-of-therapy-in-lupus-nephritis
#15
LETTER
Claudio Ponticelli, Gabriella Moroni
No abstract text is available yet for this article.
April 2020: Kidney International
https://read.qxmd.com/read/32200865/the-authors-reply
#16
LETTER
Erik J M van Bommel, Daniël H van Raalte
No abstract text is available yet for this article.
April 2020: Kidney International
https://read.qxmd.com/read/32200864/sglt2i-and-postglomerular-vasodilation
#17
LETTER
María José Soler, Esteban Porrini, Beatriz Fernandez-Fernandez, Alberto Ortiz
No abstract text is available yet for this article.
April 2020: Kidney International
https://read.qxmd.com/read/32200863/current-controversies-in-nephrology-how-to-crossmatch-for-transplantation
#18
P Toby Coates, Germaine Wong
No abstract text is available yet for this article.
April 2020: Kidney International
https://read.qxmd.com/read/32200862/virtual-crossmatching-for-deceased-donor-transplantation-one-size-does-not-fit-all
#19
David F Pinelli, Anat R Tambur
No abstract text is available yet for this article.
April 2020: Kidney International
https://read.qxmd.com/read/32200861/virtual-crossmatching-for-deceased-donor-transplantation-becomes-reality
#20
Frans H J Claas, Sebastiaan Heidt
No abstract text is available yet for this article.
April 2020: Kidney International
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