Journal of Thoracic and Cardiovascular Surgery

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OBJECTIVE: The large number of COVID-19 patients subjected to prolonged invasive mechanical ventilation has been expected to result in a significant increase of tracheal stenosis in the next years. The aim of the study was to evaluate and compare postoperative outcomes of survived COVID-19 critical illness patients who underwent tracheal resection for post-intubation/post-tracheostomy tracheal stenosis with those of non-COVID patients. METHODS: It is single-center retrospective study...

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OBJECTS: KRAS G12V is one of the most common KRAS mutation variants in lung adenocarcinoma (LUAD), and yet its prognostic value is still unrevealed. In this study, we investigated the clinicopathological characteristics and prognostic value of KRAS G12V mutation in LUAD. METHODS: Data of 3829 patients who underwent LUAD resection between 2008 and 2020 were collected. Mutations were classified as wild-type, G12V, or non-G12V. The clinicopathological characteristics, postoperative outcomes and recurrence pattern were analyzed among groups...

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BACKGROUND: Cardiac rehabilitation (CR) is a guideline-recommended risk reduction program offered to cardiac surgical patients. Despite CR's association with better outcomes, attendance remains poor. The relationship between discharge location and CR use is poorly understood. METHODS: This study was a nationwide, retrospective cohort analysis of Medicare fee-for-service claims for beneficiaries undergoing coronary artery bypass grafting and/or surgical aortic valve repair between 07/01/2016 and 12/31/2018...

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INTRODUCTION: Studies demonstrate that heart transplantation (HT) can safely be performed in septuagenarians. We evaluate outcomes of septuagenarians undergoing HT after the US heart allocation change in 2018. METHODS: The United Network for Organ Sharing (UNOS) registry was used to identify ≥70 years old HT between 2010-2021. Primary outcomes were 90-day and 1-year mortality. Kaplan-Meier, multivariable Cox proportional hazards, and accelerated failure time models were used for unadjusted and risk-adjusted analyses...

OBJECTIVE: Donation after circulatory death (DCD) donors offer the ability to expand the lung donor pool and ex vivo lung perfusion (EVLP) further contributes to this ability by allowing for additional evaluation and resuscitation of these extended criteria donors. We sought to determine the outcomes of recipients receiving organs from DCD EVLP donors in a multi-center setting. METHODS: This was an unplanned post-hoc analysis of a multicenter, prospective, non-randomized trial that took place in 2011-2017 with 3-years of follow up...

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OBJECTIVE: Peripheral regional anesthesia is proposed to enhance recovery. We sought to evaluate: the efficacy of bilateral continuous erector spinae plane blocks (B-ESpB) for postoperative analgesia and the impact on recovery in children undergoing cardiac surgery. METHODS: Patients ages 2 through 17 years undergoing cardiac surgery in the enhanced recovery after cardiac surgery (ERAS) program were prospectively enrolled to receive B-ESpB at the end of the procedure, with continuous infusions via catheters postoperatively...

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BACKGROUND: Limited comparative data guide the decision between coronary bypass surgery (CABG) versus percutaneous coronary intervention (PCI) for multivessel revascularization in ischemic cardiomyopathy. OBJECTIVES: To compare long-term outcomes of CABG and PCI for ischemic cardiomyopathy. METHODS: Clinical registries from NJ Department of Health linked to administrative databases were used to compare all-cause mortality, repeat revascularization, heart failure (HF) readmissions, myocardial infarction (MI), and stroke using Cox proportional hazards and propensity matching with competing risk analysis in 5988 patients with ejection fraction ≤35% who underwent CABG (3673,61...