journal
https://read.qxmd.com/read/38481019/analysis-of-diurnal-variation-in-serum-testosterone-levels-in-men-with-symptoms-of-testosterone-deficiency
#21
JOURNAL ARTICLE
Luis F Novaes, Jose M Flores, Nicole Benfante, Elizabeth Schofield, Darren J Katz, Chris J Nelson, John P Mulhall
BACKGROUND: Testosterone (T) plays a crucial role in various physiological functions in men, and understanding the variations in T levels during the day is essential for diagnosing and treating testosterone deficiency (TD). AIM: We sought to evaluate the reduction in serum total T (TT) levels throughout the day in men with symptoms of testosterone deficiency and to determine the variables having an impact on the extent of this decline. METHODS: The study population consisted of a group of men who within 3 months of each other had all undergone both early morning and afternoon TT level measurements...
March 13, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38481017/does-climate-impact-inflatable-penile-prosthesis-infection-ipp-risk-assessment-of-temperature-and-dew-point-on-ipp-infections
#22
JOURNAL ARTICLE
David W Barham, Nikolaos Pyrgidis, Eliad Amini, Muhammed Hammad, Jake Miller, Robert Andrianne, Arthur L Burnett, Kelli Gross, Georgios Hatzichristodoulou, James Hotaling, Tung-Chin Hsieh, Lawrence C Jenkins, James M Jones, Aaron Lentz, Vaibhav Modgil, Daniar Osmonov, Sung Hun Park, Ian Pearce, Paul Perito, Hossein Sadeghi-Nejad, Maxime Sempels, Alfredo Suarez-Sarmiento, Jay Simhan, Koenraad van Renterghem, J Nicholas Warner, Matthew Ziegelmann, Faysal A Yafi, Martin S Gross
BACKGROUND: Variations in climate have been associated with a greater risk of surgical site infections, urinary tract infections, and changes in the skin microbiome; however, limited data exist on the impact of climate on inflatable penile prosthesis (IPP) infections. AIM: We sought to evaluate the impact of climate on the risk of IPP infections in a large international, multicenter cohort. METHODS: We performed a multi-institutional, retrospective study of patients undergoing IPP surgery...
March 13, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38481013/parental-concerns-about-genital-differences-in-children-with-congenital-adrenal-hyperplasia-persist-regardless-of-the-selected-intervention
#23
JOURNAL ARTICLE
Julie Alderson, Maia Thornton, Mars Skae, Julie Jones, Nicky Nicoll, Diana Harcourt, Mark Woodward, Elizabeth C Crowne
BACKGROUND: Congenital Adrenal Hyperplasia (CAH) due to 21-hydroxylase deficiency (21HD) can affect the in utero development of the genital anatomy of people with the 46XX karyotype. Health professionals engage parents in decision-making regarding managing genitals with this difference, including genital surgery options and patient communication. AIM: We sought to investigate parental communication with their daughters regarding clitoral size variation related to neonatal CAH...
March 13, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38477106/development-and-validation-of-3-dimensional-simulators-for-penile-prosthesis-surgery
#24
JOURNAL ARTICLE
Yacov Reisman, Koen van Renterghem, Boaz Meijer, Anna Ricapito, Mikkel Fode, Carlo Bettocchi
BACKGROUND: The acquisition of skills in penile prosthesis surgery has many limitations mainly due to the absence of simulators and models for training. Three-dimensional (3D) printed models can be utilized for surgical simulations, as they provide an opportunity to practice before entering the operating room and provide better understanding of the surgical approach. AIM: This study aimed to evaluate and validate a 3D model of human male genitalia for penile prosthesis surgery...
March 13, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38477100/cldn4-overexpression-promotes-penile-cavernous-smooth-muscle-cell-fibrotic-response-via-the-jnk-signaling-pathway
#25
JOURNAL ARTICLE
Huang Jie, Wang Jie, Guo Yingxue, Zhang Xin, Xu Runnan, Huang Wenjie, Ma Jianxiong, Lv Bodong
BACKGROUND: Erectile dysfunction (ED), defined as the inability to achieve or maintain a penile erection sufficient to satisfy sexual behavior, is prevalent worldwide. AIM: Using previous research, bioinformatics, and experimental confirmation, we aimed to discover genes that contribute to ED through regulating hypoxia in corpus cavernosum smooth muscle cells (CCSMCs). METHODS: We used the Gene Expression Omnibus to acquire the sequencing data of the corpus cavernosum transcriptome for diabetic ED and nerve injury type ED rats...
March 13, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38465848/a-randomized-comparison-of-online-mindfulness-based-group-sex-therapy-vs-supportive-group-sex-education-to-address-sexual-dysfunction-in-breast-cancer-survivors
#26
JOURNAL ARTICLE
Lori A Brotto, Lauren Walker, Carly Sears, Shannon Woo, Roanne Millman, Bozena Zdaniuk
BACKGROUND: Sexual difficulties and vaginal pain are common following treatment for breast cancer. AIM: The goal of this study was to evaluate an online mindfulness-based group sex therapy vs an online supportive sex education group therapy to address these sexual difficulties. METHODS: Breast cancer survivors (n = 118) were randomized to 1 of the 2 arms; 116 provided informed consent and completed the time 1 assessment. Treatment included 8 weekly 2-hour online group sessions...
March 11, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38459625/testosterone-therapy-in-females-is-not-associated-with-increased-cardiovascular-or-breast-cancer-risk-a-claims-database-analysis
#27
JOURNAL ARTICLE
Pranjal Agrawal, Sajya M Singh, Jessica Hsueh, Aurora Grutman, Clemens An, Corey Able, Una Choi, Jaden Kohn, Marisa Clifton, Taylor P Kohn
BACKGROUND: Testosterone therapy (TTh) has been shown to improve libido in women with sexual dysfunction, but its utilization has been limited due to concern for cardiovascular events and past studies reporting highly variable results. AIM: To assess the association of TTh in women with major adverse cardiac events (MACEs), including heart attack, stroke, or death, using a large database. METHODS: The TriNetX Diamond Network was queried from 2009 to 2022...
March 8, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38451321/shh-regulates-penile-morphology-and-smooth-muscle-through-a-mechanism-involving-bmp4-and-grem1
#28
JOURNAL ARTICLE
Jiangping Deng, Sarah Martin, Timothy Searl, Samuel Ohlander, Daniel A Harrington, Kevin T McVary, Carol A Podlasek
BACKGROUND: The cavernous nerve (CN) is frequently damaged in prostatectomy and diabetic patients with erectile dysfunction (ED), initiating changes in penile morphology including an acute and intense phase of apoptosis in penile smooth muscle and increased collagen, which alter penile architecture and make corpora cavernosa smooth muscle less able to relax in response to neurotransmitters, resulting in ED. AIM: Sonic hedgehog (SHH) is a critical regulator of penile smooth muscle, and SHH treatment suppresses penile remodeling after CN injury through an unknown mechanism; we examine if part of the mechanism of how SHH preserves smooth muscle after CN injury involves bone morphogenetic protein 4 (BMP4) and gremlin1 (GREM1)...
March 6, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38451311/bmp4-and-grem1-are-targets-of-shh-signaling-and-downstream-regulators-of-collagen-in-the-penis
#29
JOURNAL ARTICLE
Jiangping Deng, Timothy Searl, Samuel Ohlander, Danuta Dynda, Daniel A Harrington, Kevin T McVary, Carol A Podlasek
BACKGROUND: Cavernous nerve (CN) injury, caused by prostatectomy and diabetes, initiates a remodeling process (smooth muscle apoptosis and increased collagen) in the corpora cavernosa of the penis of patients and animal models that is an underlying cause of erectile dysfunction (ED), and the Sonic hedgehog (SHH) pathway plays an essential role in the response of the penis to denervation, as collagen increases with SHH inhibition and decreases with SHH treatment. AIM: We examined if part of the mechanism of how SHH prevents penile remodeling and increased collagen with CN injury involves bone morphogenetic protein 4 (BMP4) and gremlin1 (GREM1) and examined the relationship between SHH, BMP4, GREM1, and collagen in penis of ED patients and rat models of CN injury, SHH inhibition, and SHH, BMP4, and GREM1 treatment...
March 6, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38441523/commentary-on-characteristics-of-systemic-testosterone-therapy-for-female-hypoactive-sexual-desire-disorder-a-claims-database-analysis
#30
JOURNAL ARTICLE
Javier Angulo
No abstract text is available yet for this article.
March 5, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38441522/double-longitudinal-myotomy-in-gender-affirming-colovaginoplasty-an-innovative-surgical-technique-to-prevent-and-treat-neovaginal-spasms
#31
JOURNAL ARTICLE
Iván Mañero Vazquez, Trinidad Labanca, Roberto Herrero
BACKGROUND: Gender-affirming colovaginoplasty (GACv) presents excellent postoperative results. However, neovaginal spasms, reported as painful cramps, can affect the sexual life of patients. AIM: The study sought to describe an innovative surgical technique and evaluate its impact on the prevention and treatment of neovaginal spasms. METHODS: This was a single-center prospective observational study with 2 series of patients: (1) patients who underwent GACv with double myotomy (DM) for spasm prevention (series A), in which longitudinal myotomies were performed across the defunctionalized colon, transecting the taenias, and resecting 2 strips of the intestinal muscle layer of approximately 1- to 2-mm wide and tall, leaving intact colonic tissue between strips; and (2) patients who reported neovaginal spasms in whom intravaginal-DM was performed as treatment surgery (series B), in which the posterior wall of the neovagina was dissected from the rectum and transected by longitudinal myotomies, resecting 2 strips of endoluminal mucosa and submucosal muscle of approximately 1- to 2-mm wide and tall, and the colonic mucosa was subsequently closed...
March 5, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38441520/characteristics-of-systemic-testosterone-therapy-for-female-hypoactive-sexual-desire-disorder-a-claims-database-analysis
#32
JOURNAL ARTICLE
Pranjal Agrawal, Yeonsoo Sara Lee, Aurora J Grutman, Kathryn Dumas, Taylor Kohn, Jaden Kohn, Alyssa M Yee, Marisa Clifton
BACKGROUND: Testosterone therapy (TTh) is recommended for postmenopausal women with hypoactive sexual desire disorder (HSDD); however, there remain insufficient data to support use of TTh in premenopausal women with sexual dysfunction. AIM: In this study, we used a large national database to evaluate prescribing trends of TTh for women with HSDD. METHODS: We conducted a cohort analysis of information from electronic health records acquired from the data network TriNetX Diamond...
March 5, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38441479/a-healthy-lifestyle-can-support-future-sexual-satisfaction-results-from-a-9-year-longitudinal-survey
#33
JOURNAL ARTICLE
Säde Stenlund, Lauri Sillanmäki, Heli Koivumaa-Honkanen, Päivi Rautava, Hanna Lagström, Sakari Suominen
BACKGROUND: Previous follow-up studies have demonstrated the association between good health behavior and good sexual functioning for men, but the longitudinal relationship between multiple health behaviors and satisfaction with sex life remains understudied. AIM: The aim of the study was to explore whether good health behavior associates with improved satisfaction with sex life for men and women in a follow-up of 9 years. METHODS: This cohort study utilized survey data from the population-based Health and Social Support study...
March 5, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38427555/a-european-network-for-the-investigation-of-gender-incongruence-in-adolescents
#34
JOURNAL ARTICLE
Lidewij S Boogers, Chantal M Wiepjes, Annemieke S Staphorsius, Daniel T Klink, Silvia Ciancia, Alessia Romani, Tessa H R Stolk, Emmy van den Boogaard, Thomas D Steensma, Annelou L C de Vries, A S Paul van Trotsenburg, Martin den Heijer, Alessandra D Fisher, Martine Cools, Sabine E Hannema
BACKGROUND: Knowledge regarding the effects and side effects of gender-affirming hormone therapy (GAHT) in adults is rapidly growing, partly through international research networks such as the European Network for the Investigation of Gender Incongruence (ENIGI). However, data on the effects of puberty suppression (PS) and GAHT in transgender and gender diverse (TGD) youth are limited, although these data are of crucial importance, given the controversies surrounding this treatment. AIM: We sought to present a detailed overview of the design of the ENIGI Adolescents study protocol, including the first baseline data...
March 1, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38427462/effects-of-sexual-counseling-on-sexual-function-and-sexual-quality-of-life-of-women-with-permanent-intestinal-ostomy
#35
JOURNAL ARTICLE
Fatemeh Sohrabi, Batool Tirgari, Milad Safaei, Sajjad Alizadeh
BACKGROUND: Patients with an intestinal ostomy may experience significant sexual dysfunction that may have adverse impacts on quality of life. Appropriate sexual health counseling can be beneficial for these patients. AIM: This study was conducted to determine the effect of sexual counseling on the sexual function and sexual quality of life of women with a permanent intestinal ostomy. METHODS: For this experimental study, 60 female patients with a permanent intestinal ostomy were selected through convenience sampling and then randomly assigned to either the intervention or control groups...
March 1, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38430132/sexual-medicine-society-of-north-america-smsna-american-urological-association-aua-telemedicine-and-men-s-health-white-paper
#36
JOURNAL ARTICLE
Mohit Khera, Helen L Bernie, Gregory Broderick, Serge Carrier, Martha Faraday, Tobias Kohler, Lawrence Jenkins, Daniel Watter, John Mulhall, Omer Raheem, Ranjith Ramasamy, Rachel Rubin, Aaron Spitz, Faysal Yafi, Hossein Sadeghi-Nejad
PURPOSE: The purpose of this white paper is to educate health care professionals about the evolution of telemedicine (TM) and to propose a hybrid model that leverages the strengths of traditional in-person medicine as well as virtual medicine while maximizing the safety and quality of men's sexual health care. LITERATURE SEARCH STRATEGY: A literature search focused on the use of TM in urology and men's health was performed through PubMed/MEDLINE, Embase, and Web of Science (January 1, 2012-April 26, 2022)...
February 28, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38410031/communication-and-sexual-function-and-frequency-in-breast-cancer-patients-2%C3%A2-years-after-diagnosis-results-from-the-vican-2-study
#37
JOURNAL ARTICLE
Thierry Almont, Prisca Ouowéné Sougué, Rémi Houpert, Murielle Beaubrun-Renard, Christelle Montabord, Clarisse Joachim, Jacqueline Véronique-Baudin, Anne-Déborah Bouhnik, Marc-Karim Bendiane, Julien Mancini, Éric Huyghe
BACKGROUND: Breast cancer treatments may have impacts on several aspects of sexual health, including psychological, psychosexual, physiological, physical, and relational. AIM: In this study we sought to assess sexual function and sexual frequency in breast cancer patients 2 years after diagnosis. METHODS: We selected all breast cancer participants from the the French national VIe après le CANcer 2 (VICAN 2) longitudinal study. Data sources included patient and medical questionnaires, along with medico-administrative databases...
February 26, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38693840/avoiding-vascular-complications-at-the-time-of-penile-implant-surgery
#38
JOURNAL ARTICLE
D Osmonov, S K Wilson
No abstract text is available yet for this article.
April 30, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38693839/potential-leads-and-insights-for-the-management-of-sexual-problems-from-a-disgust-perspective
#39
EDITORIAL
Charmaine Borg, Peter J de Jong
No abstract text is available yet for this article.
April 30, 2024: Journal of Sexual Medicine
https://read.qxmd.com/read/38563590/repeated-sexual-intercourse-as-a-coping-strategy-for-men-with-premature-ejaculation
#40
JOURNAL ARTICLE
Chunlin Wang, Elena Colonnello, Andrea Sansone, Hui Zhang, Emmanuele A Jannini, Yan Zhang
BACKGROUND: Patients with premature ejaculation (PE) are often concerned and distressed about their sexual performance. Hence, they may be more willing to exploit their refractory period to employ sexual coping strategies in order to improve their unsatisfactory sexual intercourse compared with patients without PE. AIM: The study sought to verify the sexual coping strategies of patients with PE in the daily sexual activities. METHODS: We included both patients with PE and individuals without PE and analyzed their sexual behaviors and attitudes by means of detailed interviews and questionnaires...
April 30, 2024: Journal of Sexual Medicine
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