Raquel Alarcon-Rodriguez, Rafael García-Álvarez, Rosario Fadul-Calderon, Raúl Romero-Del Rey, Mar Requena-Mullor, Madelyn Read Tejada, Jessica Garcia-Gonzalez
BACKGROUND: Female orgasmic disorder is listed in the DSM-5 and is defined as the persistent or recurrent inability to have an orgasm. Many depressed women may experience sexual dysfunction, including female orgasmic disorder. AIM: The study sought to analyze the relationship between depressive disorders and attention-deficit/hyperactivity disorder (ADHD) and their influence on the development of female orgasmic disorder. METHODS: A total of 221 Dominican women participated in this case-control study...
April 16, 2024: Journal of Sexual Medicine
Gláucia Miranda Varella Pereira, Luiz Gustavo Oliveira Brito, Nina Ledger, Cássia Raquel Teatin Juliato, Claudine Domoney, Rufus Cartwright
BACKGROUND: Female sexual dysfunction (FSD), including vaginal laxity (VL), can lead to a decrease in quality of life and affect partner relationships. AIM: We aimed to investigate the associated factors of VL and FSD and their relationship with other pelvic floor disorders in a female population. METHODS: This cross-sectional study was conducted at Chelsea and Westminster Hospital from July to December 2022. All women referred to clinical care at the urogynecology clinic were included...
April 13, 2024: Journal of Sexual Medicine
Uday Mann, Dhiraj S Bal, Kapilan Panchendrabose, Ranveer Brar, Premal Patel
BACKGROUND: The relationship between erectile dysfunction (ED) and cardiovascular (CV) events has been postulated, with ED being characterized as a potential harbinger of CV disease. Location of residence is another important consideration, as the impact of rural residence has been associated with worse health outcomes. AIM: To investigate whether men from rural settings with ED are associated with a higher risk of major adverse CV events (MACEs). METHODS: A propensity-weighted retrospective cohort study was conducted with provincial health administrative databases...
April 10, 2024: Journal of Sexual Medicine
Dimitrios Kalyvianakis, Ioannis Mykoniatis, Nikolaos Pyrgidis, Paraskeui Kapoteli, Filimon Zilotis, Dimitrios Hatzichristou
BACKGROUND: Patients with severe erectile dysfunction (ED) remain the most challenging group in terms of available noninvasive treatment modalities. AIM: The study sought to assess the role of combination therapy with low-intensity shockwave therapy (LiST) and daily tadalafil 5 mg in a highly select group of patients with severe vasculogenic ED through a double-blind, randomized trial. METHODS: Forty-eight sexually active men were randomly assigned to 12 sessions of LiST 3 times weekly and tadalafil 5 mg once daily (n = 34) or sham therapy and tadalafil (n = 17) for 4 weeks...
April 10, 2024: Journal of Sexual Medicine
Shari M Blumenstock, Kelly Suschinsky, Lori A Brotto, Meredith L Chivers
BACKGROUND: Models depicting sexual desire as responsive to sexual arousal may be particularly apt for women experiencing arousal or desire difficulties, and the degree to which arousal triggers desire may depend on the relationship context and desire target and timing-yet, these associations have not been directly tested among women with and without sexual interest/arousal disorder (SIAD). AIM: To assess the role of SIAD status and relationship satisfaction in the associations between genital arousal and 4 types of responsive desire...
April 6, 2024: Journal of Sexual Medicine
Chunlin Wang, Elena Colonnello, Andrea Sansone, Hui Zhang, Emmanuele A Jannini, Yan Zhang
BACKGROUND: Patients with premature ejaculation (PE) are often concerned and distressed about their sexual performance. Hence, they may be more willing to exploit their refractory period to employ sexual coping strategies in order to improve their unsatisfactory sexual intercourse compared with patients without PE. AIM: The study sought to verify the sexual coping strategies of patients with PE in the daily sexual activities. METHODS: We included both patients with PE and individuals without PE and analyzed their sexual behaviors and attitudes by means of detailed interviews and questionnaires...
April 1, 2024: Journal of Sexual Medicine
Sandrine Dubé, Noémie Beaulieu, Sophie Bergeron, Marie-France Lafontaine, Katherine Péloquin, Anne Brault-Labbé, Patrick Gosselin, Audrey Brassard
BACKGROUND: Genitopelvic pain following childbirth is common and likely to challenge the psychological, relational, and sexual well-being of new mothers. While genitopelvic pain generally decreases during the postpartum period, personal and interpersonal characteristics may explain why genitopelvic pain persists beyond the period of physical recovery in some mothers. Body image concerns, increased stress, and relationship challenges would be particularly salient during pregnancy and the postpartum period, which could put new mothers at greater risk of sexual difficulties...
March 31, 2024: Journal of Sexual Medicine
Erhan Ates, Mustafa Gok, Hakan Gorkem Kazici, Arif Kol, Tuna Sahin, Haluk Erol
BACKGROUND: Although premature ejaculation (PE) is the most common male sexual dysfunction, the underlying mechanisms are not fully understood. AIM: The study sought to evaluate the possible associations among glans penis volume and tissue stiffness measured using penile ultrasonography and penile shear wave elastography (SWE) with PE. METHODS: Men 18 to 65 years of age with normal International Index of Erectile Function scores (>25) and who were diagnosed with PE between June 2021 and June 2022 were enrolled...
March 28, 2024: Journal of Sexual Medicine
Alexandra Drian, Sue W Goldstein, Noel N Kim, Andrew S Goldstein, Rose Hartzell-Cushanick, Alyssa Yee, Irwin Goldstein
BACKGROUND: Neuroproliferative vestibulodynia (NPV), a provoked genital pain characterized by severe allodynia and hyperalgesia, is confirmed in excised vestibular tissue by immunohistochemical staining (>8 CD117-positive immunostained cells/100× microscopic field) rather than by hematoxylin and eosin staining. AIM: In this study we sought to assess immunostaining of tissue samples obtained during vestibulectomy surgery and to correlate results with patient outcomes...
March 23, 2024: Journal of Sexual Medicine
Jill M Krapf, Isabella Kopits, Jessica Holloway, Sylvia Lorenzini, Theodora Mautz, Andrew T Goldstein
BACKGROUND: Keratin pearls are foci of central keratinization within concentric layers of squamous cells that can form under the clitoral prepuce and cause pain (clitorodynia); in-office removal of keratin pearls may reduce clitoral pain and improve sexual function. AIM: This study aims to investigate clitoral pain and sexual function in women with partial clitoral phimosis and keratin pearls before and after in-office lysis of clitoral adhesions with keratin pearl excision (LCA-KPE)...
March 21, 2024: Journal of Sexual Medicine
Nina Bohm-Starke, Caroline Pukall, Marie Österberg, Maria Ahlberg, Ann Kristine Jonsson, Sofia Tranæus, Susanna Kempe, Christel Hellberg
BACKGROUND: There is an inconsistency in treatment outcomes used in clinical trials for provoked vestibulodynia (PVD), which makes it impossible to compare the effects of different interventions. AIM: In this study, we completed the first step in creating a core outcome set (COS), defining what outcomes should be measured in clinical trials for PVD. METHODS: Identification of outcomes used in studies was done by extracting data from clinical trials in a recently published systematic review and via review of clinical trials for PVD registered on ClinicalTrials...
March 21, 2024: Journal of Sexual Medicine
Noemi Ricucci, Elena Colonnello, Erika Limoncin, Daniele Mollaioli, Andrea Sansone, Emmanuele A Jannini, Giacomo Ciocca
BACKGROUND: Among the plethora of urogynecological conditions possibly affecting women, some of them, less explored, have significant impacts on sexological and psychological health, with a mutual influence. AIM: The aim of this study was to investigate the sexological and psychological correlates of four urogynecological pathologies in a sample of women of childbearing age: overactive pelvic floor, vulvodynia, postcoital cystitis, and interstitial cystitis. Women cured of these conditions were also included, to assess the same aspects after the remission of physical symptoms...
March 21, 2024: Journal of Sexual Medicine
Glaucia Miranda Varella Pereira, Rufus Cartwright, Cássia Raquel Teatin Juliato, Claudine Domoney, Cheryl B Iglesia, Luiz Gustavo Oliveira Brito
BACKGROUND: Despite several treatments that have been used for women reporting vaginal laxity (VL), to our knowledge no systematic review is available on the topic so far. AIM: In this study, we sought to summarize the best available evidence about the efficacy and safety of interventions for treating VL, whether conservative or surgical. METHODS: A comprehensive search strategy was performed in Medline, Embase, Scopus, Web of Science, and Cochrane Library for reports of clinical trials published from database inception to September 2022...
March 20, 2024: Journal of Sexual Medicine
Ghazale Samiei, Zahra Mehrbakhsh, Hamideh Khosravi, Sedigheh Moghasemi
BACKGROUND: Genital self-image is among the factors affecting women's sexual function. AIM: The present study aimed to determine changes in the genital self-image and its relationship with women's sexual function in the third trimester of pregnancy and postpartum. METHODS: The participants of this prospective cohort study included 301 eligible pregnant women chosen through stratified random sampling with proportional allocation from comprehensive health centers in Gorgan, Iran...
March 18, 2024: Journal of Sexual Medicine
Rachel Carmen Ceasar, Seyedeh-Sanam Ladi-Seyedian, Domenique Escobar, Jullet Han, Kailyn Koh, Sima Porten, Carissa Chu, Erin E Gould, Sumeet Bhanvadia
BACKGROUND: Women's sexual health after radical cystectomy is an important but poorly understood aspect of bladder cancer survivorship. Dedicated investigation is needed to elucidate patient perceptions on sexual function and dysfunction in this setting. AIMS: In this study we sought to qualitatively examine women's perceptions and experiences of sexual health following radical cystectomy for bladder cancer. METHODS: We conducted one-on-one qualitative telephone interviews with 40 women who underwent radical cystectomy in the past 6 months to 5 years and signed a research consent form to be contacted for future studies...
March 15, 2024: Journal of Sexual Medicine
Priscila A Vasconcelos, Constança Paúl, Pedro J Nobre
BACKGROUND: Given the unprecedented aging of the population and the increased focus on overall well-being in older age, investigating the determining factors of sexual well-being in older adults becomes essential as it offers insights into promoting healthy aging and overall quality of life. AIM: By applying the biopsychosocial model of sexuality in older age, we aimed to identify the role of biomedical and psychosocial factors in predicting sexual well-being in partnered older adults (≥55 years old)...
March 15, 2024: Journal of Sexual Medicine
Luis F Novaes, Jose M Flores, Nicole Benfante, Elizabeth Schofield, Darren J Katz, Chris J Nelson, John P Mulhall
BACKGROUND: Testosterone (T) plays a crucial role in various physiological functions in men, and understanding the variations in T levels during the day is essential for diagnosing and treating testosterone deficiency (TD). AIM: We sought to evaluate the reduction in serum total T (TT) levels throughout the day in men with symptoms of testosterone deficiency and to determine the variables having an impact on the extent of this decline. METHODS: The study population consisted of a group of men who within 3 months of each other had all undergone both early morning and afternoon TT level measurements...
March 13, 2024: Journal of Sexual Medicine
David W Barham, Nikolaos Pyrgidis, Eliad Amini, Muhammed Hammad, Jake Miller, Robert Andrianne, Arthur L Burnett, Kelli Gross, Georgios Hatzichristodoulou, James Hotaling, Tung-Chin Hsieh, Lawrence C Jenkins, James M Jones, Aaron Lentz, Vaibhav Modgil, Daniar Osmonov, Sung Hun Park, Ian Pearce, Paul Perito, Hossein Sadeghi-Nejad, Maxime Sempels, Alfredo Suarez-Sarmiento, Jay Simhan, Koenraad van Renterghem, J Nicholas Warner, Matthew Ziegelmann, Faysal A Yafi, Martin S Gross
BACKGROUND: Variations in climate have been associated with a greater risk of surgical site infections, urinary tract infections, and changes in the skin microbiome; however, limited data exist on the impact of climate on inflatable penile prosthesis (IPP) infections. AIM: We sought to evaluate the impact of climate on the risk of IPP infections in a large international, multicenter cohort. METHODS: We performed a multi-institutional, retrospective study of patients undergoing IPP surgery...
March 13, 2024: Journal of Sexual Medicine
Julie Alderson, Maia Thornton, Mars Skae, Julie Jones, Nicky Nicoll, Diana Harcourt, Mark Woodward, Elizabeth C Crowne
BACKGROUND: Congenital Adrenal Hyperplasia (CAH) due to 21-hydroxylase deficiency (21HD) can affect the in utero development of the genital anatomy of people with the 46XX karyotype. Health professionals engage parents in decision-making regarding managing genitals with this difference, including genital surgery options and patient communication. AIM: We sought to investigate parental communication with their daughters regarding clitoral size variation related to neonatal CAH...
March 13, 2024: Journal of Sexual Medicine
Yacov Reisman, Koen van Renterghem, Boaz Meijer, Anna Ricapito, Mikkel Fode, Carlo Bettocchi
BACKGROUND: The acquisition of skills in penile prosthesis surgery has many limitations mainly due to the absence of simulators and models for training. Three-dimensional (3D) printed models can be utilized for surgical simulations, as they provide an opportunity to practice before entering the operating room and provide better understanding of the surgical approach. AIM: This study aimed to evaluate and validate a 3D model of human male genitalia for penile prosthesis surgery...
March 13, 2024: Journal of Sexual Medicine
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