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Journal of Pediatric Gastroenterology and Nutrition

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https://read.qxmd.com/read/30985443/psychologic-distress-and-anxiety-in-mothers-of-children-with-gastroesophageal-reflux-undergoing-antireflux-surgery
#1
Morten Kvello, Tone Lise Åvitsland, Charlotte K Knatten, Thomas J Fyhn, Ulrik Malt, Ragnhild Emblem, Kristin Bjørnland
OBJECTIVES: Parents of children with a chronic illness are at risk for impaired psychosocial functioning. Gastroesophageal reflux disease (GERD) is such a disease, and no studies have investigated effects of antireflux surgery on parental psychological distress. The aims of this study were to assess psychological distress and state and trait anxiety in mothers of children with GERD, and to explore possible changes after antireflux surgery. METHODS: Mothers of children referred for antireflux surgery were included in this prospective study...
April 9, 2019: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/30985442/substance-use-in-adolescents-and-young-adults-with-inflammatory-bowel-diseases-an-exploratory-cluster-analysis
#2
Jill M Plevinsky, Michele H Maddux, Rachel N Greenley
OBJECTIVES: Adolescents and young adults (AYAs) with chronic illnesses use substances at similar, if not greater, rates compared to healthy peers. The present study aimed to examine rates and patterns of tobacco use, marijuana use, and binge drinking in AYAs with inflammatory bowel diseases (IBD). We expected that substance use would be associated with poorer physical health, psychosocial functioning, and disease management. METHODS: One hundred thirty-two AYAs completed a single set of surveys assessing demographics, disease activity, healthcare utilization, health-related quality of life (HRQoL), IBD-specific self-efficacy, adherence barriers, disease management skills, and substance use in the last 30 days (e...
April 9, 2019: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/30964823/orbezoar-a-superabsorbent-polymer-causing-small-bowel-obstruction-in-a-toddler
#3
Theodoros Michelakos, Mari Tanaka, Madhukar S Patel, Daniel P Ryan
No abstract text is available yet for this article.
April 1, 2019: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/30964822/differential-intraoperative-effect-of-liver-transplant-in-different-inborn-errors-of-metabolism
#4
Francesco Porta, Renato Romagnoli, Marta Busso, Francesco Tandoi, Marco Spada
Liver transplant (LT) is a therapeutic option for a growing number of inborn errors of metabolism (IEM), including some disorders not confined to the liver. Clinical advantages of LT in maple syrup urine disease (MSUD), methylmalonic acidemia (MMA), and argininosuccinic aciduria (ASA) have been reported. However, no information on the early metabolic effect of LT after portal reperfusion is available in these disorders. Here we describe the intraoperative differential metabolic outcome of LT in MSUD, MMA, and ASA...
April 1, 2019: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/30964821/paediatric-endoscopy-global-rating-scale-development-of-a-quality-improvement-tool-and-results-of-a-national-pilot
#5
Priya Narula, Raphael Broughton, Lucy Howarth, Anna Piggott, Ronald Bremner, Christos Tzivinikos, Peter Gillett, Paul Henderson, David Rawat, Mick Cullen, Sabari Loganathan, David Devadason, Nadeem A Afzal, Janis Maginnis, Sharon McKenna, Mike Thomson, John Green, Debbie Johnston
INTRODUCTION AND OBJECTIVES: The endoscopy Global Rating Scale (GRS) is a web-based self-assessment quality improvement (QI) tool that provides a framework for service improvement. Widespread use of the GRS in adult endoscopy services in the United Kingdom (UK) has led to a demonstrable improvement in quality. The adult GRS is not directly applicable to paediatric endoscopy services. The objective of this study is to develop and pilot a paediatric endoscopy Global Rating Scale (P-GRS) as a QI tool...
April 1, 2019: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/30964820/randomized-controlled-trial-of-oropharyngeal-colostrum-administration-in-very-low-birth-weight-preterm-infants
#6
Daniela M L M Ferreira, Angela M M Oliveira, Débora V de Leves, Érica B de Bem, Giovana G Fatureto, Natássia F Navarro, Nathália G Afonso, Fernanda M Santiago, José R Mineo, Mônica C Sopelete, Francisco E Martinez, Morun Bernardino Neto, Vânia O S Abdallah
OBJECTIVE: The purpose of this study was to evaluate the effects of oropharyngeal colostrum administration in the incidence of late-onset clinical and proven sepsis and in concentrations of immunoglobulin A (IgA) in very-low-birth-weight (VLBW) infants. METHODS: We conducted a double-blinded, randomized, placebo-controlled trial and assigned 113 VLBW infants to receive 0.2 mL of maternal colostrum or sterile water (placebo) via oropharyngeal route every 2 hours for 48 hours, beginning in the first 48 to 72 hours of life...
April 1, 2019: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/30964819/inflammatory-bowel-disease-serological-immune-markers-anti-saccharomyces-cerevisiae-mannan-antibodies-and-outer-membrane-porin-c-are-potential-biomarkers-for-hirschsprung-associated-enterocolitis
#7
Philip K Frykman, Deven C Patel, Sungjin Kim, Zhi Cheng, Tomas Wester, Agneta Nordenskjöld, Akemi Kawaguchi, Thomas T Hui, Peter F Ehrlich, Anna L Granström, Filip Benliyan
OBJECTIVE: Hirschsprung-associated enterocolitis (HAEC) is the most frequent complication in Hirschsprung disease (HSCR) patients. Currently HAEC is diagnosed clinically, leaving uncertainty in the diagnosis thereby potentially leading to over- or undertreatment of patients. The aim of this study was to identify immune biomarkers to aid in the diagnosis of HAEC. METHODS: From 2012 to 2017, 43 children with HSCR enrolled in a multicenter study, underwent retrospective evaluation of their medical records, and questionnaire-directed parent interviews...
April 1, 2019: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/30964818/a-path-to-consensus-on-endoscopic-pancreatic-function-testing
#8
Daniel Gelfond
No abstract text is available yet for this article.
April 1, 2019: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/30964817/improving-ibd-transition-self-management-and-disease-outcomes-with-an-in-clinic-transition-coordinator
#9
Wendy N Gray, Erin Holbrook, Dana Dykes, Pamela J Morgan, Shehzad A Saeed, Lee A Denson
OBJECTIVES: Deficits in the preparation of patients with inflammatory bowel disease (IBD) who are transitioning to adult care are known yet studies presenting outcome data of transition interventions in IBD are lacking. We present data evaluating the impact of a transition coordinator on behavioral and clinical transition outcomes. METHODS: A retrospective chart review identified 135 patients who had met with our transition coordinator and completed the Transition Readiness Assessment Questionnaire before, and 1 year after, the intervention...
April 1, 2019: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/30921262/infliximab-paradoxical-psoriasis-in-a-cohort-of-children-with-inflammatory-bowel-disease
#10
Olivier Courbette, Camille Aupiais, Jerome Viala, Jean-Pierre Hugot, Baptiste Louveau, Lucienne Chatenoud, Emmanuelle Bourrat, Christine Martinez-Vinson
OBJECTIVES: In adult inflammatory bowel disease (IBD) treated by anti-TNF antibodies, paradoxical psoriasis has an estimated prevalence of 1.6 to 22%, especially in infliximab (IFX)-treated patients. Little is known in the pediatric IBD (PIBD) populations. METHODS: All patients aged from 2 to 18 years with Crohn's disease (CD) or Ulcerative colitis (UC) and treated for the first time by IFX between January 2002 and March 2014, were considered for inclusion in this retrospective study performed in a tertiary PIBD centre...
March 26, 2019: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/30921261/hepatic-venous-pressure-gradient-measurements-in-children-correlation-with-hepatic-histology-and-clinical-indicators-of-portal-hypertension
#11
Noelle H Ebel, Kristen Carlin, Michele L Shaffer, Giri Shivaram, C Matthew Hawkins, Erin R Lane, Kara Cooper, Will S Lindquester, Gaurav Gadodia, Karen F Murray
OBJECTIVES: In adults, elevated hepatic venous pressure gradients (HVPGs) are correlated with the degree of liver fibrosis on histopathology and predict worse outcomes including variceal bleeding and death. We aimed to examine the association between HVPG measurements, histopathologic findings, and clinical indicators of portal hypertension in children. METHODS: Utilizing retrospective data from 2 pediatric centers between 2006 and 2015, we identified children who underwent simultaneous HVPG measurement and transjugular liver biopsy...
March 26, 2019: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/30921260/pediatric-celiac-disease-and-eosinophilic-esophagitis-outcome-of-dietary-therapy
#12
Tiffany Patton, Ankur Chugh, Leena Padhye, Catherine DeGeeter, Stefano Guandalini
OBJECTIVE: The coexistence of celiac disease (CeD) and eosinophilic esophagitis (EoE) in pediatric patients has been increasingly recognized. In the current study, we have aimed to assess the outcomes of therapeutic dietary interventions in a cohort of pediatric patients with CeD and EoE. METHODS: Pediatric patient records obtained from the University of Chicago Celiac Center Database from August 2008 to July 2013 were reviewed. Information was collected on patients with concomitant CeD and EoE regarding age, gender, dates of diagnoses, presenting symptoms, length of symptoms prior to diagnosis, familial and personal atopic history, dietary therapy, and esophageal histologic response to dietary therapy...
March 26, 2019: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/30921259/a-symptom-self-report-tool-for-children-with-inflammatory-bowel-disease-ibdnow
#13
Angharad Vernon-Roberts, Robert N Lopez, Chris Frampton, Richard B Gearry, Daniel A Lemberg, Andrew S Day
OBJECTIVES: Clinical symptom evaluation for children with inflammatory bowel disease (IBD) is typically done using composite tools: the Pediatric Crohn's Disease Activity Index (PCDAI) and Pediatric Ulcerative Colitis Activity Index (PUCAI). Both rely on clinician interpretation of child or parent symptom recall. No universal self-report tool has yet been developed for children with IBD to assess and report their symptoms. The research objective was to develop a self-report tool that produced information congruent with that obtained by clinicians using the PUCAI or PCDAI...
March 26, 2019: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/30921258/sensitivity-and-specificity-of-administrative-medical-coding-for-pediatric-eosinophilic-esophagitis
#14
Jacob Robson, Kent Korgenski, Karyn Moss, Amber McClain, Carlos Barbagelata, Kristina Allen-Brady, Raza Patel, Molly O'Gorman, Kathryn Peterson, Stephen Guthery
OBJECTIVES: Eosinophilic esophagitis (EoE) is a delayed-type hypersensitivity with increasing rates among pediatric populations. Although studies have used International Classification of Diseases (ICD) coding to define local cohorts and report disease epidemiology, the accuracy of the EoE ICD code for pediatric EoE is unknown. METHODS: We searched the Intermountain Healthcare Database for pediatric cases with the EoE ICD code over a 5-year period. We cross-referenced these results with a recently published pediatric EoE cohort from the same region and period, where incident cases were identified via retrospective review of pathology reports and medical records...
March 26, 2019: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/30921257/a-unified-treatment-algorithm-and-admission-order-set-for-pediatric-acute-pancreatitis
#15
Zachary M Sellers, Chinenye Dike, Ke-You Zhang, Matthew J Giefer, Aliye Uc, Maisam Abu-El-Haija
No abstract text is available yet for this article.
March 26, 2019: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/30921256/development-of-a-patient-reported-experience-and-outcomes-measure-in-pediatric-patients-undergoing-bowel-management-for-constipation-and-fecal-incontinence
#16
Devin R Halleran, Victoria A Lane, Karen L Leonhart, Beth Fischer, Yuri Sebastiao, Deena J Chisolm, Marc A Levitt, Richard J Wood, Peter C Minneci, Katherine J Deans
AIMS AND OBJECTIVES: To develop a reliable and valid questionnaire that assesses patient reported experience (PREMs) and patient reported outcome measures (PROMs) of caregivers, families, and patients with severe constipation and fecal incontinence who failed conservative treatments and require a formal bowel management program (BMP). METHODS: A five step iterative process was utilized to ensure the reliability and validity of the final instrument. Parents or guardians of patients undergoing our week-long BMP were first asked 20 open-ended questions aimed at understanding the challenges in managing their child's condition...
March 26, 2019: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/30921255/incontinence-in-phelan-mcdermid-syndrome
#17
Claire Witmer, Aviva Mattingly, Precilla DʼSouza, Audrey Thurm, Colleen Hadigan
OBJECTIVE: To evaluate gastrointestinal symptoms and continence in the context of Phelan-McDermid Syndrome (PMS). STUDY DESIGN: A prospective evaluation of children with PMS (n = 17) at the National Institutes of Health. RESULTS: Parent-reported history of symptoms were common: constipation (65%), reflux (59%), choking/gagging (41%), and more than half received gastrointestinal specialty care. No aspiration was noted in 11/11 participants who completed modified barium swallows...
March 26, 2019: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/30921254/esophagitis-in-pediatric-esophageal-atresia-acid-may-not-always-be-the-issue
#18
Jessica L Yasuda, Susannah J Clark, Steven J Staffa, Bradley Blansky, Peter D Ngo, Thomas E Hamilton, C Jason Smithers, Russell Jennings, Michael A Manfredi
OBJECTIVE: Esophagitis is highly prevalent in patients with esophageal atresia (EA). Peptic esophagitis has long been assumed to be the primary cause of esophagitis in this population, and prolonged acid suppressive medication usage is common; such treatment is of unknown benefit and carries potential risk. METHODS: To better understand the role of commonly used antireflux treatments in EA, we analyzed all patients with repaired EA who underwent endoscopy with biopsies at our institution between January 2016 and August 2018...
March 26, 2019: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/30921253/pancreatoscopy-directed-electrohydraulic-lithotripsy-in-a-pediatric-patient-with-pancreas-divisum-and-cystic-fibrosis
#19
Karen Queliza, Isaac Raijman, Douglas S Fishman
No abstract text is available yet for this article.
March 26, 2019: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/30921252/sedation-and-the-fda-warning-what-a-pediatric-gastroenterologist-hepatologist-and-pancreatologist-should-know
#20
Douglas S Fishman, Dean B Andropoulos, Jenifer R Lightdale
Pediatric gastroenterologists recommend and perform a range of procedures requiring sedation and anesthesia in young children. A recent warning from the US FDA states that "repeated or lengthy use of general anesthetics and sedation drugs during surgeries or procedures in children younger than 3 years or in pregnant women during their third trimester may affect the development of children's brains.' 1 As it relates to time, the FDA warning details risks of 'procedures lasting longer than 3 hours or if multiple procedures are required...
March 26, 2019: Journal of Pediatric Gastroenterology and Nutrition
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