Jeffrey P Mullin, Mohamed A R Soliman, Justin S Smith, Michael P Kelly, Thomas J Buell, Bassel Diebo, Justin K Scheer, Breton Line, Virginie Lafage, Renaud Lafage, Eric Klineberg, Han Jo Kim, Peter G Passias, Jeffrey L Gum, Khaled Kebaish, Robert K Eastlack, Alan H Daniels, Alex Soroceanu, Gregory Mundis, Richard Hostin, Themistocles S Protopsaltis, D Kojo Hamilton, Munish C Gupta, Stephen J Lewis, Frank J Schwab, Lawrence G Lenke, Christopher I Shaffrey, Shay Bess, Christopher P Ames, Douglas Burton
OBJECTIVE: Complex spinal deformity surgeries may involve significant blood loss. The use of antifibrinolytic agents such as tranexamic acid (TXA) has been proven to reduce perioperative blood loss. However, for patients with a history of thromboembolic events, there is concern of increased risk when TXA is used during these surgeries. This study aimed to assess whether TXA use in patients undergoing complex spinal deformity correction surgeries increases the risk of thromboembolic complications based on preexisting thromboembolic risk factors...
March 8, 2024: Journal of Neurosurgery. Spine