Yangzhi Qi, Yang Xu, Tengfeng Yan, Wei Xiong, Xinyi Zhu, Qian Sun, Gang Deng, Fanen Yuan, Liguo Ye, Ping Hu, Baohui Liu, Shenqi Zhang, Shuhang Deng, Yan He, Gao Wu, Qingsong Ye, Qianxue Chen
OBJECTIVE: Circulating tumor cell (CTC) detection is a promising noninvasive technique that can be used to diagnose cancer, monitor progression, and predict prognosis. In this study, the authors aimed to investigate the clinical utility of CTCs in the management of diffuse glioma. METHODS: Sixty-three patients with newly diagnosed diffuse glioma were included in this multicenter clinical cohort. The authors used a platform based on isolation by size of epithelial tumor cells (ISET) to detect and analyze CTCs and circulating tumor microemboli (CTMs) in the peripheral blood of patients both before and after surgery...
April 12, 2024: Journal of Neurosurgery