Jason Tasoulas, Douglas R Farquhar, Siddharth Sheth, Trevor Hackman, Wendell G Yarbrough, Chris B Agala, Alzina Koric, Luca Giraldi, Eleonora Fabianova, Jolanta Lissowska, Beata Świątkowska, Marta Vilensky, Victor Wünsch-Filho, Marcos Brasilino de Carvalho, Rossana Verónica Mendoza López, Ivana Holcátová, Diego Serraino, Jerry Polesel, Cristina Canova, Lorenzo Richiardi, Jose P Zevallos, Andy Ness, Miranda Pring, Steve J Thomas, Tom Dudding, Yuan-Chin Amy Lee, Mia Hashibe, Paolo Boffetta, Andrew F Olshan, Kimon Divaris, Antonio L Amelio
BACKGROUND: Poor oral health has been identified as a prognostic factor potentially affecting the survival of patients with head and neck squamous cell carcinoma. However, evidence to date supporting this association has emanated from studies based on single cohorts with small-to-modest sample sizes. METHODS: Pooled analysis of 2449 head and neck squamous cell carcinoma participants from 4 studies of the International Head and Neck Cancer Epidemiology Consortium included data on periodontal disease, tooth brushing frequency, mouthwash use, numbers of natural teeth, and dental visits over the 10 years prior to diagnosis...
September 19, 2023: Journal of the National Cancer Institute