Purbita Bandopadhyay, Ranit D' Rozario, Abhishake Lahiri, Jafar Sarif, Yogiraj Ray, Shekhar Ranjan Paul, Rammohan Roy, Rajshekhar Maiti, Kausik Chaudhuri, Saugata Bagchi, Ayan Maiti, Md Masoom Perwez, Biswanath Sharma Sarkar, Devlina Roy, Rahul Chakraborty, Janani Srinivasa Vasudevan, Sachin Sharma, Durba Biswas, Chikam Maiti, Bibhuti Saha, Prasun Bhattacharya, Rajesh Pandey, Shilpak Chatterjee, Sandip Paul, Dipyaman Ganguly
Novel coronavirus SARS-CoV2, causing coronavirus disease 2019 or COVID-19, led to significant morbidity and mortality. While most suffer from mild symptoms, some patients progress to a severe disease with acute respiratory distress syndrome (ARDS) and an associated systemic hyper-inflammation. First to characterize key cytokines and their dynamics in this hyper-inflammatory condition, we assessed abundance and correlative expression of a panel of forty eight cytokines in patients progressing to ARDS, as compared to patients with mild disease...
January 12, 2021: Journal of Infectious Diseases