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Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract

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https://read.qxmd.com/read/30783957/effect-of-topical-baclofen-5-on-post-hemorrhoidectomy-pain-randomized-double-blind-placebo-controlled-clinical-trial
#1
Shahram Ala, Mina Alvandipour, Majid Saeedi, Mohaddeseh Mansourifar, Mahila Monajati, Afshin Shiva
BACKGROUND: Baclofen is an agonist for a subtype of gamma-amino butyric acid (GABA-B) receptors and traditionally been used for the systemic treatment of spasticity. Topical application of baclofen has been shown to reduce pain in patients with localized neuropathic pain. OBJECTIVES: In this study, we investigate the efficacy of baclofen cream (5%) in reducing postoperative pain and analgesic requirement after open hemorrhoidectomy. DESIGN: The patients were randomly assigned to either baclofen (5%) cream or placebo immediately after surgery and then every 12 h for 14 days...
February 19, 2019: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://read.qxmd.com/read/30783956/successful-use-of-the-recanalized-remnant-umbilical-vein-as-a-patch-graft-for-venous-reconstruction-in-abdominal-surgery
#2
Björn-Ole Stüben, Asmus Heumann, Julian Stürznickel, Jakob R Izbicki, Jun Li
Various approaches have been described for the reconstruction of the portal vein (PV), superior mesenteric vein (SMV), and the inferior vena cava (IVC). We present the use of the recanalized remnant umbilical vein in various settings including transplantation, major liver resection, and pancreatic surgery. We retrospectively analyzed four cases, in which a recanalized remnant umbilical vein was used for vascular reconstruction. The graft harvesting, size of the graft, technique of application, and short-term results of vascular patency were studied...
February 19, 2019: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://read.qxmd.com/read/30771211/comparison-of-the-extent-classification-and-the-new-complexity-classification-of-hepatectomy-for-prediction-of-surgical-outcomes-a-retrospective-cohort-study
#3
Xiao-Long Wu, Zhi-Yu Li, Yong Jiang, Xinyu Bi, Hong Zhao, Jian-Jun Zhao, Zhen Huang, Ye-Fan Zhang, Jian-Qiang Cai
BACKGROUND: In predicting the risk for posthepatectomy complications, hepatectomy is traditionally classified into minor or major resection based on the number of resected segments. Recently, a new hepatectomy complexity classification was proposed. This study aimed to compare the value of the traditional and that of the new classification in perioperative outcomes prediction. METHODS: Demographics, perioperative laboratory tests, intraoperative and postoperative outcomes, and follow-up data of patients with hepatocellular carcinoma who underwent liver resection were retrospectively analyzed...
February 15, 2019: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://read.qxmd.com/read/30761469/feasibility-and-safety-of-spleno-aortic-bypass-in-patients-with-atheromatous-celiac-trunk-stenosis-in-pancreaticoduodenectomy
#4
LETTER
Tullio Piardi, Rami Rhaiem, Arman Aghei, Francesco Fleres, Yohann Renard, Ambroise Duprey, Daniele Sommacale, Reza Kianmanesh
No abstract text is available yet for this article.
February 13, 2019: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://read.qxmd.com/read/30761468/gastric-plexiform-fibromyxoma
#5
Sudeep Banerjee, Jorge de la Torre, Adam M Burgoyne, Ann M Ponsford Tipps, Thomas J Savides, Jason K Sicklick
No abstract text is available yet for this article.
February 13, 2019: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://read.qxmd.com/read/30761467/comparable-data-between-double-endoscopic-intraluminal-operation-and-conventional-endoscopic-submucosal-dissection-for-esophageal-cancer
#6
Makoto Sohda, Kengo Kuriyama, Tomonori Yoshida, Yuji Kumakura, Hiroaki Honjo, Makoto Sakai, Tatsuya Miyazaki, Hiroyuki Kuwano
BACKGROUND: Endoscopic submucosal dissection (ESD) of superficial esophageal cancer has been used increasingly as an alternative to surgery because it is minimally invasive and has a high rate of en bloc resection. We previously reported that the double endoscopic intraluminal operation (DEILO) is a useful technique for ESD of early esophageal cancers. In the current study, we showed comparable short-term data between DEILO and conventional ESD groups to demonstrate the further advanced use of DEILO...
February 13, 2019: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://read.qxmd.com/read/30761466/gastric-hemorrhage-caused-by-heterotopic-pancreas
#7
Priscilla Chamberlain, Anoop Prabhu, Filip Bednar
No abstract text is available yet for this article.
February 13, 2019: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://read.qxmd.com/read/30756316/laparoscopic-parenchymal-sparing-hepatectomy-the-new-maximally-minimal-invasive-surgery-of-the-liver-a-systematic-review-and-meta-analysis
#8
Jennifer A Kalil, Jennifer Poirier, Bjoern Becker, Robert Van Dam, Xavier Keutgen, Erik Schadde
BACKGROUND: Parenchymal-sparing hepatectomies (PSH) are liver resections with preservation of as much liver parenchyma as possible. PSH can be performed laparoscopically (LPSH), but access to the posterosuperior segments is difficult and they are challenging when there are multiple bilobar lesions; the procedure may require repositioning and may be long and cumbersome. The objective of this systematic review is to analyze the feasibility and limitations of laparoscopic PSH in the literature...
February 12, 2019: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://read.qxmd.com/read/30756315/patient-derived-xenografts-can-be-reliably-generated-from-patient-clinical-biopsy-specimens
#9
Matthew C Hernandez, John R Bergquist, Jennifer L Leiting, Tommy Ivanics, Lin Yang, Rory L Smoot, David M Nagorney, Mark J Truty
BACKGROUND: Patient-derived xenografts (PDX) are clinically relevant human cancer models that can be used to guide individualized medicine. We aimed to generate PDX models from clinically obtained biopsy specimens (surgical or image-guided) hypothesizing that low volume biopsy specimens could provide sufficient viable tissue to successfully engraft PDX models from patients with unresectable or metastatic disease. MATERIALS AND METHODS: We maintain a prospective high volume gastrointestinal malignancy PDX program...
February 12, 2019: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://read.qxmd.com/read/30756314/evaluation-of-the-new-american-joint-committee-on-cancer-staging-manual-8th-edition-for-perihilar-cholangiocarcinoma
#10
Marcia P Gaspersz, Stefan Buettner, Jeroen L A van Vugt, Jeroen de Jonge, Wojciech G Polak, Michail Doukas, Jan N M Ijzermans, Bas Groot Koerkamp, François E J A Willemssen
BACKGROUND: The aim was to compare the prognostic accuracy of cross-sectional imaging of the 7th and 8th editions of the American Joint Committee on Cancer(AJCC) staging system for perihilar cholangiocarcinoma(PHC). METHODS: All patients with PHC between 2002 and 2014 were included. Imaging at the time of presentation was reassessed and clinical tumor-node-metastasis (cTNM) stage was determined according to the 7th and 8th editions of the AJCC staging system. Comparison of the prognostic accuracy was performed using the concordance index (c-index)...
February 12, 2019: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://read.qxmd.com/read/30734182/venous-thromboembolism-in-necrotizing-pancreatitis-an-underappreciated-risk
#11
Alexandra M Roch, Thomas K Maatman, Rose A Carr, Cameron L Colgate, Eugene P Ceppa, Michael G House, James Lopes, Attila Nakeeb, C Max Schmidt, Nicholas J Zyromski
BACKGROUND: Necrotizing pancreatitis (NP) is a severe systemic inflammatory process. We have observed a high incidence of venous thromboembolism (VTE) in NP patients. However, remarkably few data exist to document the true incidence of VTE-including splanchnic vein thrombosis (SVT), extremity deep venous thrombosis (eDVT), and pulmonary embolism (PE)-in NP. Therefore, we sought to determine the incidence and risk factors for VTE in NP patients. METHODS: Retrospective review of all NP patients treated at a single academic center between 2005 and 2015...
February 7, 2019: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://read.qxmd.com/read/30734181/spontaneous-gastric-decompression-of-walled-off-pancreatic-necrosis
#12
Sonia Cohen, David G Forcione, Peter J Fagenholz
No abstract text is available yet for this article.
February 7, 2019: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://read.qxmd.com/read/30734180/comprehensive-characterization-of-a-porcine-model-of-the-small-for-flow-syndrome
#13
Maitane I Orue-Echebarria, Javier Vaquero, Cristina J Lisbona, Pablo Lozano, Miguel A Steiner, Álvaro Morales, José Á López-Baena, Juan Laso, Inmaculada Hernández, Luis Olmedilla, José L García Sabrido, Isabel Peligros, Emma Sola, Carlos Carballal, Elena Vara, J M Asencio
INTRODUCTION: The term "Small-for-Flow" reflects the pathogenetic relevance of hepatic hemodynamics for the "Small-For-Size" syndrome and posthepatectomy liver failure. We aimed to characterize a large-animal model for studying the "Small-for-Flow" syndrome. METHODS: We performed subtotal (90%) hepatectomies in 10 female MiniPigs using a simplified transection technique with a tourniquet. Blood tests, hepatic and systemic hemodynamics, and hepatic function and histology were assessed before (Bas), 15 min (t-15 min) and 24 h (t-24 h) after the operation...
February 7, 2019: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://read.qxmd.com/read/30734179/first-experience-with-banded-anti-reflux-mucosectomy-arms-for-gerd-feasibility-safety-and-technique-with-video
#14
Herbert Mason Hedberg, Kristine Kuchta, Michael B Ujiki
BACKGROUND: Anti-reflux mucosectomy (ARMS) is a relatively new endoscopic procedure for gastroesophageal reflux disease (GERD). A hemi-circumferential endoscopic mucosal resection (EMR) is performed around the gastroesophageal junction (GEJ), which then contracts and tightens during healing. The aim of this study was to assess the feasibility and safety of the procedure. A secondary aim was to assess short-term outcomes on PPI use and symptom resolution. METHODS: IRB approval was obtained for retrospective review of a prospectively collected database including patients who underwent ARMS during a 2-year period...
February 7, 2019: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://read.qxmd.com/read/30729373/the-role-of-adjuvant-chemotherapy-in-ypt0n0-rectal-adenocarcinoma
#15
Anita Nguyen, David R James, Eric J Dozois, Scott R Kelley, Kellie L Mathis
BACKGROUND: In patients who develop a complete pathologic response (ypT0N0) following neoadjuvant chemoradiation, the benefits of postoperative chemotherapy remain uncertain. This study aims to determine whether treatment with adjuvant chemotherapy in ypT0N0 patients affects short- and long-term outcomes. METHODS: From January 2000 to December 2015, 992 patients at our institution underwent surgery for rectal adenocarcinoma following treatment with neoadjuvant chemoradiation...
February 6, 2019: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://read.qxmd.com/read/30719679/early-infectious-complications-after-total-pancreatectomy-with-islet-autotransplantation-a-single-center-experience
#16
Justyna E Gołębiewska, Piotr J Bachul, Natalie Fillman, Mark R Kijek, Lindsay Basto, Monica Para, Laurencia Perea, Karolina Gołąb, Ling-Jia Wang, Martin Tibudan, Alicja Dębska-Ślizień, Jeffrey B Matthews, John Fung, Piotr Witkowski
INTRODUCTION: We assessed whether positive microbiological cultures from the islet preparation had any effect on the risk of infectious complications (IC) after total pancreatectomy with islet autotransplantation (TPIAT) in our center. METHODS: We analyzed preservation fluid and final islet product surveillance cultures with reference to clinical data of patients undergoing TPIAT. All patients received routine prophylactic broad-spectrum antibiotics. RESULTS: The study involved 10 men and 18 women with a median age of 39 years...
February 4, 2019: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://read.qxmd.com/read/30719678/inferior-outcomes-associated-with-the-coexistence-of-hepatocellular-carcinoma-recurrence-and-hepatic-virus-reinfection-after-living-donor-liver-transplantation
#17
Kun-Ming Chan, Tsung-Han Wu, Chih-Hsien Cheng, Chen-Fang Lee, Ting-Jung Wu, Hong-Shiue Chou, Wei-Chen Lee
BACKGROUND: Chronic viral hepatitis remains a major etiology of liver cirrhosis and hepatocellular carcinoma. Liver transplantation has been considered an effective treatment for this condition. This study aims to analyze living donor liver transplantation for patients with hepatocellular carcinoma and its relationship with hepatitis virus status. METHODS: A retrospective analysis of 268 patients who received living donor liver transplantation for hepatocellular carcinoma was performed...
February 4, 2019: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://read.qxmd.com/read/30719677/variation-in-the-thoroughness-of-pathologic-assessment-and-response-rates-of-locally-advanced-rectal-cancers-after-chemoradiation
#18
Oliver S Chow, Sujata Patil, Metin Keskin, J Joshua Smith, Maria Widmar, David D Smith, Karin Avila, Jinru Shia, Peiguo Chu, Julio Garcia-Aguilar
BACKGROUND: Pathologic complete response (pCR) is associated with better prognosis and guides management for patients with advanced rectal cancer. Response rates vary between series for unclear reasons. We examine whether the thoroughness of pathologic assessment explains differences in pCR rates. METHODS: We retrospectively reviewed pathology reports from patients with stage II/III rectal cancer who underwent chemoradiation and resection in a prospective, multicenter trial...
February 4, 2019: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://read.qxmd.com/read/30719676/impact-of-liver-cirrhosis-on-perioperative-outcomes-among-elderly-patients-undergoing-hepatectomy-the-effect-of-minimally-invasive-surgery
#19
Kota Sahara, Anghela Z Paredes, Diamantis I Tsilimigras, J Madison Hyer, Katiuscha Merath, Lu Wu, Rittal Mehta, Eliza W Beal, Susan White, Itaru Endo, Timothy M Pawlik
BACKGROUND: The impact of cirrhosis on perioperative outcomes for elderly patients undergoing hepatectomy remains not well defined. We sought to determine the influence of underlying cirrhosis and minimally invasive surgery (MIS) on postoperative outcomes among elderly patients who underwent a hepatectomy. METHODS: Patients who underwent hepatectomy between 2013 and 2015 were identified using the Center for Medicare Services (CMS) 100% Limited Data Set (LDS) Standard Analytic Files (SAFs)...
February 4, 2019: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://read.qxmd.com/read/30719675/laparoscopic-versus-open-major-hepatectomy-analysis-of-clinical-outcomes-and-cost-effectiveness-in-a-high-volume-center
#20
Federica Cipriani, Francesca Ratti, Arianna Cardella, Marco Catena, Michele Paganelli, Luca Aldrighetti
BACKGROUND: Considering the increasing evidence on the feasibility of laparoscopic major hepatectomies (LMH), their clinical outcomes and associated costs were herein evaluated compared to open (OMH). METHODS: Major contributors of perioperative expenses were considered. With respect to the occurrence of conversion, a primary intention-to-treat analysis including conversions in the LMH group (ITT-A) was performed. An additional per-protocol analysis excluding conversions (PP-A) was undertaken, with calculation of additional costs of conversion analysis...
February 4, 2019: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
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