journal
https://read.qxmd.com/read/38959495/borderline-personality-disorder-and-eating-disorders-investigating-the-role-of-emotion-regulation
#1
JOURNAL ARTICLE
Samantha C Dashineau, Caroline E Balling, Susan C South, Mark Zimmerman
Objective: Borderline personality disorder (BPD) and eating disorders (EDs) both cause significant distress and co-occur at rates higher than expected, signifying potential overlapping regulatory mechanisms between both disorders. More specifically, both disorders involve emotion regulation deficits, suggesting they may share specific maladaptive regulatory components. The present study sought to examine the predictive role of emotion dysregulation within the comorbidity between EDs and BPD. Methods: A sample of psychiatric outpatients (N = 872) collected from a longitudinal study spanning the mid-1990s to 2015 completed the Structured Clinical Interview for DSM-IV for Axis I Disorders as well as a measure of emotion regulation strategies, the Difficulties in Emotion Regulation Scale, in order to assess overall functioning...
July 3, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38959494/epilepsy-antiepileptic-drugs-and-adverse-pregnancy-outcomes-2-major-congenital-malformations-with-antiepileptic-drug-monotherapy
#2
REVIEW
Chittaranjan Andrade
Women with epilepsy (WWE) are usually advised antiepileptic drug (AED) treatment even during pregnancy. It is therefore important to know what the major congenital malformation (MCM) risks might be with untreated epilepsy, and with first-trimester exposure to different AEDs in monotherapy. This article reviews recent findings from a large multinational registry, a large multinational population based study, and a large meta-analysis. In summary, data from the meta-analysis suggest that the MCM rate is 2%-3% in women without epilepsy and about 3% in WWE who were unexposed to AEDs during pregnancy...
July 3, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38959498/controlled-study-of-metabolic-syndrome-among-offspring-of-parents-with-bipolar-disorder
#3
JOURNAL ARTICLE
Nidhi P Kulkarni, Mikaela K Dimick, Kody G Kennedy, David A Axelson, Dara J Sakolsky, Rasim S Diler, Danella M Hafeman, Tina R Goldstein, Kelly J Monk, Fangzi Liao, John A Merranko, Boris Birmaher, Benjamin I Goldstein
Objectives: Bipolar disorder (BD) is highly heritable and associated with increased rates of metabolic syndrome (MetS). However, little is known about MetS in offspring of parents with BD. We therefore examined this topic in the Pittsburgh Bipolar Offspring Study cohort. Methods: Participants included 199 parents (n = 116 BD, diagnosed using DSM-IV ; n = 83 non-BD) and 330 offspring (mean age 19.9 ± 5.3 years), including 198 high-risk offspring of parents with BD (n = 80 affected with a mood disorder) and 132 control offspring...
July 1, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38959503/immune-targeted-therapies-for-depression-current-evidence-for-antidepressant-effects-of-monoclonal-antibodies
#4
REVIEW
Mina M Rizk, Lindsay Bolton, Flurin Cathomas, Helen He, Scott J Russo, Emma Guttman-Yassky, J John Mann, James Murrough
Importance: Increasing evidence suggests a potential role of immune-modulatory drugs for treatment-resistant depression. This scoping review explores the emerging evidence regarding the antidepressant effects of monoclonal antibodies (mAbs), a relatively newer class of immune therapeutics with favorable safety profile. Observations: PubMed was searched up to November 2023 for English publications addressing the antidepressant effects of mAbs, including meta-analyses, randomized controlled trials, open-label, single-arm studies, and case series...
June 24, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38959502/mental-health-assessments-for-fetal-interventions
#5
JOURNAL ARTICLE
Sindhura Vangala, Roy Williams, Cara M Buskmiller, Jessian L Munoz
No abstract text is available yet for this article.
June 24, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38917361/depression-rumination-and-suicide-attempts-in-adolescents-with-mood-disorders-sex-differences-in-this-relationship
#6
JOURNAL ARTICLE
Dianying Liu, Gang Lei, Dian Li, Hongdong Deng, Xiang Yang Zhang, Yonghui Dang
Abstract . Background: Sex differences in suicide attempts have been widely recognized across domains such as depression and rumination. The relationship between depression, rumination, and suicide attempts in mood disorders has been studied before; however, how they interact across sexes remains unclear. This study aimed to examine the sex differences in the relationship between depression, rumination, and suicide attempts in Chinese adolescents with mood disorders. Methods: We recruited 681 adolescents with mood disorders who met ICD-10 criteria for having unipolar or bipolar depression with a current depressive episode at the time of the study and collected demographic and clinical data...
June 19, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38917366/efficacy-and-safety-of-esmethadone-rel-1017-in-patients-with-major-depressive-disorder-and-inadequate-response-to-standard-antidepressants-a-phase-3-randomized-controlled-trial
#7
RANDOMIZED CONTROLLED TRIAL
Maurizio Fava, Stephen M Stahl, Luca Pani, Sara De Martin, Andrew J Cutler, Vladimir Maletic, Charles W Gorodetzky, Frank J Vocci, Frank L Sapienza, Thomas R Kosten, Cornelia Kröger, Paggard Champasa, Cedric O'Gorman, Clotilde Guidetti, Andrea Alimonti, Stefano Comai, Andrea Mattarei, Franco Folli, David Bushnell, Sergio Traversa, Charles E Inturrisi, Paolo L Manfredi, Marco Pappagallo
Objective: To test esmethadone (REL-1017) as adjunctive treatment in patients with major depressive disorder (MDD) and inadequate response to standard antidepressants. Methods: In this phase 3, double-blind, placebo-controlled trial, outpatients with MDD ( DSM-5 ) were randomized to daily oral esmethadone (75 mg on day 1, followed by 25 mg daily on days 2 through 28) or placebo between December 2020 and December 2022. The primary efficacy measure was change from baseline (CFB) to day 28 in the Montgomery-Asberg Depression Rating Scale (MADRS) score...
June 17, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38917365/jcp-s-focus-on-women-s-mental-health-twenty-years-and-counting
#8
EDITORIAL
Marlene P Freeman
No abstract text is available yet for this article.
June 17, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38874573/prevalence-and-trends-in-cigarette-smoking-with-and-without-tobacco-use-disorder-among-adults-in-the-united-states-2010-2021
#9
JOURNAL ARTICLE
Joanna M Streck, Maria A Parker, Raul Cruz, Rachel L Rosen, Timothy B Baker, Megan E Piper, Andrea H Weinberger
Objective: Few national estimates are available on the prevalence of tobacco use disorder (TUD) in the United States (US), and most trials exclusively assess daily smoking rather than TUD. We examined the prevalence and trends in cigarette smoking with vs without TUD among adults. Methods: Data came from the 2010-2021 National Survey on Drug Use and Health (n = 483,982), a cross sectional, US representative dataset. A TUD composite variable was created based on established definitions (eg, DSM-5 symptoms). Weighted prevalence of past 30-day cigarette smoking, daily smoking (30/30 days) and nondaily smoking (<30/30 days) with and without TUD, was calculated annually...
June 12, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38874575/extreme-dysphoria-of-pregnancy-a-distinct-syndrome-warranting-attention
#10
JOURNAL ARTICLE
Marlene P Freeman
No abstract text is available yet for this article.
June 10, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38874574/pharmacogenomic-characterization-of-childbearing-aged-individuals-with-mood-disorders-in-a-tertiary-care-perinatal-mental-health-clinic
#11
JOURNAL ARTICLE
Jessica L W Mayer, Hannah K Betcher, Laura J Rasmussen-Torvik, Amy Yang, Alfred L George, Tatiana Abramova, Catherine S Stika, Katherine L Wisner, Crystal T Clark, Jacqueline Gollan
Objective: The effectiveness of antidepressant treatment for mood disorders is often limited by either a poor response or the emergence of adverse effects. These complications often necessitate multiple drug trials. This clinical challenge intensifies during pregnancy, when medications must be selected to improve the likelihood of response and optimize reproductive outcomes. We determined the distribution of common pharmacogenetic variants, metabolizer phenotypes, past medication responses, and side effects in childbearing-aged individuals seeking treatment in a tertiary care perinatal mental health clinic...
June 10, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38836868/using-thc-edible-gummies-for-behavioral-symptoms-of-dementia-reply-to-goldman-and-markov
#12
LETTER
Erin K Zahradnik, Cristian Hernandez
No abstract text is available yet for this article.
June 5, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38836867/cognitive-effects-of-electroconvulsive-therapy-in-schizophrenia-a-systematic-review
#13
JOURNAL ARTICLE
Sophie R Vaccarino, Anthony L Vaccarino
Objective: To determine the objective cognitive effects of electroconvulsive therapy (ECT) in treatment-resistant schizophrenia (TRS). Data Sources: A database search of MEDLINE, PsycINFO, and Embase was conducted on September 22, 2022, using the search terms "schizophrenia" and "electroconvulsive therapy." The search was limited to the articles published from 1985 to present, in English, and human studies. Study Selection: A total of 4293 articles were identified. After screening by title and full text, 17 articles met eligibility criteria...
June 5, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38836866/epilepsy-antiepileptic-drugs-and-adverse-pregnancy-outcomes-1-examination-and-interpretation-of-recent-research
#14
JOURNAL ARTICLE
Chittaranjan Andrade
The age-standardized global prevalence of epilepsy is about 0.3% in women. Seizures are associated with morbidity and mortality risks; so, women with epilepsy (WWE) are usually advised antiepileptic drug (AED) treatment even during pregnancy. Women may also knowingly or unknowingly be exposed during pregnancy to AEDs advised for other on- or off-label indications. In this context, a meta-analysis of 35 adverse gestational outcomes examined in 76 observational studies found that WWE were at increased risk of most of the adverse outcomes, regardless of gestational exposure to AEDs...
June 5, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38836865/what-s-gender-got-to-do-with-it-accounting-for-differences-in-incident-guideline-discordant-prescribing-for-ptsd-among-women-and-men-veterans
#15
JOURNAL ARTICLE
Kenda R Stewart Steffensmeier, Katherine Hadlandsmyth, Nancy Bernardy, Daniel Ball, Nicole L Johnson, Jennifer Van Tiem, Brian C Lund
Objectives: Women veterans are more likely than men veterans to receive medications that Department of Veterans Affairs clinical practice guidelines recommend against to treat posttraumatic stress disorder (PTSD). To understand this difference, we examined potential confounders in incident prescribing of guideline discordant medications (GDMs) in veterans with PTSD. Methods: Veterans receiving care for PTSD during 2020 were identified using Veterans Health Administration administrative data. PTSD diagnosis was established by the presence of at least 1 ICD-10 coded outpatient encounter or inpatient hospitalization during the calendar year 2020...
June 5, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38836864/why-ask-patients-to-cut-into-quarters-10-mg-thc-gummies-obtained-from-a-cannabis-dispensary-when-2-5-mg-thc-dronabinol-is-available-by-prescription
#16
JOURNAL ARTICLE
Marina Goldman, Dfapa Dimitri Markov
No abstract text is available yet for this article.
June 5, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38836860/daily-and-cumulative-sleep-duration-as-predictors-of-suicidal-desire-and-intent-an-ecological-momentary-assessment-study
#17
JOURNAL ARTICLE
Megan L Rogers, Melanie L Bozzay
Objective: Shorter sleep duration has been linked to increased suicidal ideation (SI). However, limited research has examined the relationship between nightly sleep duration and short-term fluctuations in suicide risk, as well as the potential clinical utility of leveraging indices of recent (ie, past 3 days) patterns of sleep duration as a marker of acute suicide risk. This study examined associations between nightly and cumulative sleep duration and suicidal desire and intent utilizing ecological momentary assessment (EMA) in a high risk sample of community-based adults...
June 3, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38836859/longitudinal-trajectories-of-depressive-symptoms-and-their-associations-with-risks-of-underweight-and-obesity-in-women-a-population-based-longitudinal-study-in-korea
#18
JOURNAL ARTICLE
Seong-Uk Baek, Yu-Min Lee, Jong-Uk Won, Jin-Ha Yoon
Objective: We explored depressive symptom trajectories and their associations with underweight and obesity in Korean women. Methods: This prospective cohort study involved 7,691 women enrolled in the Korean Longitudinal Survey of Women and Families, with a follow-up period spanning from 2014 to 2020. Depressive symptoms were evaluated through the 10-item version of the Center of Epidemiologic Studies Depression Scale. Growth mixture modeling was employed to identify trajectories of depressive symptoms. Multinomial logistic regressions were conducted to investigate the correlation between depression trajectories and the evolving risks of underweight and obesity over the study period...
June 3, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38836858/the-co-occurrence-of-depression-and-obesity-implications-for-clinical-practice-and-the-discovery-of-targeted-and-precise-mechanistically-informed-therapeutics
#19
JOURNAL ARTICLE
Roger S McIntyre
No abstract text is available yet for this article.
June 3, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38836857/dark-was-the-night-sleep-alterations-as-proximal-markers-for-suicide-risk
#20
JOURNAL ARTICLE
Pierre A Geoffroy
No abstract text is available yet for this article.
June 3, 2024: Journal of Clinical Psychiatry
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