journal
https://read.qxmd.com/read/38629708/severity-of-antipsychotic-induced-cervical-dystonia-assessed-by-the-algorithm-based-rating-system
#1
JOURNAL ARTICLE
Toshiya Inada, Yuta Tanabe, Yuji Fukaya, Kazuyoshi Ogasawara, Nobutomo Yamamoto
Background: The severity of antipsychotic-induced cervical dystonia has traditionally been evaluated visually. However, recent advances in information technology made quantification possible in this field through the introduction of engineering methodologies like machine learning. Methods: This study was conducted from June 2021 to March 2023. Psychiatrists rated the severity of cervical dystonia into 4 levels (0: none, 1: minimal, 2: mild, and 3: moderate) for 101 videoclips, recorded from 87 psychiatric patients receiving antipsychotics...
April 15, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38602493/psychological-pain-as-a-risk-factor-for-suicidal-ideation-an-ecological-momentary-assessment-study-on-inpatients-with-depression-with-and-without-comorbid-borderline-personality-disorder
#2
JOURNAL ARTICLE
Ilya Baryshnikov, Tom H Rosenström, Erkki T Isometsä
Objective: Psychological pain (PP) is a potentially important risk factor for suicide. However, its temporal stability and association with suicidal ideation (SI) remain obscure. Whether PP represents a risk factor for SI independently of depression, anxiety, and hopelessness or is more prominent and temporally unstable in patients with depression and borderline personality disorder (BPD) is also unclear. Methods: From November 2020 to December 2022, psychiatric inpatients with depression without (N = 37) and with (N = 30) BPD were recruited to an ecological momentary assessment (EMA) study, wherein their PP, severity of depression, SI, and hopelessness were assessed 3 times daily using visual analog scales...
April 8, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38569181/serotonin-syndrome-and-dextromethorphan-toxicity-caused-by-drug-drug-interaction-between-fluoxetine-and-bupropion-dextromethorphan-a-case-report
#3
JOURNAL ARTICLE
Michelle Anjali Singh, Devon Johnson
No abstract text is available yet for this article.
April 3, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38569179/ssri-behavioral-activation-the-boxed-bolded-warning-and-neurodevelopmental-disorders
#4
JOURNAL ARTICLE
Mayank Gupta
No abstract text is available yet for this article.
April 2, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38535509/associations-of-valproate-doses-with-weight-gain-in-adult-psychiatric-patients-a-1-year-prospective-cohort-study
#5
JOURNAL ARTICLE
Claire Grosu, William Hatoum, Marianna Piras, Nermine Laaboub, Setareh Ranjbar, Franziska Gamma, Kerstin J Plessen, Armin von Gunten, Martin Preisig, Philippe Conus, Chin B Eap
Objective: The aim of this study was to evaluate valproate dose association with weight change, blood glucose, lipid levels, and blood pressure in a psychiatric population. Methods: Data from 215 patients taking valproate for up to 1 year were collected from 2 longitudinal studies that monitored metabolic variables between 2007 and 2022. Linear mixed-effect models and logistic regressions were used to analyze the associations between valproate doses and metabolic outcomes. Results: An increase in valproate dose of 500 mg was associated with a weight change of +0...
March 27, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38535508/valproate-and-weight-gain-a-new-look-at-an-old-problem
#6
COMMENT
Joseph F Goldberg
No abstract text is available yet for this article.
March 27, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38518288/does-the-onset-of-efficacy-for-agitation-vary-depending-on-the-administration-route-of-antipsychotics
#7
JOURNAL ARTICLE
Xintong Mu, Hiroyoshi Takeuchi
No abstract text is available yet for this article.
March 20, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38488388/effects-of-prenatal-exposure-to-second-generation-antipsychotics-on-development-and-behavior-among-preschool-aged-children-preliminary-results-from-the-national-pregnancy-registry-for-psychiatric-medications
#8
JOURNAL ARTICLE
Carol Swetlik, Lee S Cohen, Lauren A Kobylski, Ellen T Sojka, Parker C Killenberg, Marlene P Freeman, Adele C Viguera
Objective: Data are lacking on the neurodevelopmental outcomes of children prenatally exposed to second-generation antipsychotics (SGAs). The objective of this study is to examine neurodevelopmental outcomes of children exposed in utero to SGAs compared to those unexposed in a cohort of mothers with psychiatric morbidity. Methods: We conducted a cross-sectional assessment of preschool-aged children whose mothers were enrolled in the National Pregnancy Registry for Psychiatric Medications. Two validated, parent-report developmental and behavioral screening assessments, the Ages and Stages Questionnaire, Third Edition (ASQ-3) and the Preschool Child Behavior Checklist for Ages 1½-5 (CBCL/1½-5), respectively, were delivered electronically to eligible participants...
March 13, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38451170/randomized-controlled-trial-of-a-brief-video-intervention-to-reduce-self-stigma-of-mental-illness
#9
RANDOMIZED CONTROLLED TRIAL
Doron Amsalem, Samantha E Jankowski, Philip Yanos, Lawrence H Yang, John C Markowitz, R Tyler Rogers, T Scott Stroup, Lisa B Dixon, Leah G Pope
Objective: Self-stigma, a phenomenon wherein individuals internalize self-directed negative stereotypes about mental illness, is associated with negative outcomes related to recovery. This randomized controlled study assessed the efficacy of a brief social contact-based video intervention in reducing self-stigma in a large sample of individuals ages 18-35 endorsing an ongoing mental health condition. We hypothesized that the brief video would reduce self-stigma. Methods: In January and February 2023, we recruited and assigned 1,214 participants to a brief video-based intervention depicting a young individual living with mental illness sharing his personal story or to a non-intervention control...
March 6, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38416865/safety-and-tolerability-of-starting-aripiprazole-lauroxil-with-aripiprazole-lauroxil-nanocrystal-dispersion-in-1-day-followed-by-aripiprazole-lauroxil-every-2-months-using-paliperidone-palmitate-monthly-as-an-active-control-in-patients-with-schizophrenia-a
#10
RANDOMIZED CONTROLLED TRIAL
Leslie Citrome, Sergey Yagoda, Ilda Bidollari, Meihua Wang
Background: Aripiprazole lauroxil (AL) 1064 mg every 2 months following initiation using the AL NanoCrystal Dispersion formulation (ALNCD ) plus 30-mg oral aripiprazole was efficacious and well tolerated in a 25-week, randomized, double-blind phase 3 trial in adults with acute schizophrenia. This post hoc analysis further characterized the safety of AL 1064 mg administered every 2 months and that of active control paliperidone palmitate (PP) 156 mg monthly based on occurrence, timing, and severity of adverse events (AEs) associated with antipsychotic medications...
February 28, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38385994/associations-of-msk1-methylation-and-executive-function-with-suicidal-ideation-in-adolescents-with-major-depressive-disorder-a-prospective-cohort-study
#11
JOURNAL ARTICLE
Peiwei Xu, Yuanmei Tao, Hang Zhang, Meijiang Jin, Hanmei Xu, Shoukang Zou, Fang Deng, Lijuan Huang, Hong Zhang, Xiaolan Wang, Xiaowei Tang, Yanping Wang, Li Yin, Xueli Sun
Objective: Adolescent suicide is a major public health problem, and risk of suicide is higher among those with major depressive disorder (MDD), which may be linked to alterations in mitogen- and stress-activated kinase 1 (MSK1) and to defects in executive function. Here, we aimed to investigate the potential impacts of executive function and MSK1 methylation on suicidal ideation in adolescents with MDD. Methods: The study enrolled 66 drug-naive adolescents who were experiencing their first episode of MDD from February 2019 until October 2020...
February 21, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38353646/what-does-a-systematic-review-of-cannabis-and-ptsd-tell-us-that-we-need-to-learn-more
#12
COMMENT
Michael J Ostacher
No abstract text is available yet for this article.
February 14, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38353645/a-systematic-review-of-the-clinical-effects-of-cannabis-and-cannabinoids-in-posttraumatic-stress-disorder-symptoms-and-symptom-clusters
#13
JOURNAL ARTICLE
Justyne D Rodas, Tony P George, Ahmed N Hassan
Objective: Given the high rate of comorbid posttraumatic stress disorder (PTSD) and cannabis use, it is critical that further research be conducted to address the associated benefits and risks of cannabis use in this population. This systematic review evaluated evidence on the effects of cannabis and cannabinoids on PTSD symptoms and PTSD clusters. Data Sources: A systematic search of PubMed, PsycINFO, and EMBASE databases was performed using terms related to cannabis, cannabinoids, and PTSD. Peer-reviewed studies available online in English and published from January 1990 through February 2023 were considered...
February 14, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38324731/physical-exercise-and-health-6-sedentary-time-independent-of-health-related-physical-activity-as-a-risk-factor-for-dementia-in-older-adults
#14
JOURNAL ARTICLE
Chittaranjan Andrade
Sedentary behaviors are leisurely behaviors that occur during waking hours performed while lying down or seated; examples are relaxing, conversing, using a smartphone, watching television, traveling in private or public transport, and thinking or working at a desk. Sedentary behaviors are common in everyday life; the average person spends 9-10 h/d sedentary. Findings from meta-analyses show that higher levels of physical activity are associated with a reduced risk of dementia and that near-absence of moderate to vigorous physical activity is associated with an increased risk of dementia...
February 7, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38324730/truth-keeping-us-on-track-in-scientific-publishing
#15
JOURNAL ARTICLE
Marlene P Freeman
No abstract text is available yet for this article.
February 5, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38301186/effect-of-lurasidone-on-social-functioning-in-schizophrenia-post-hoc-analysis-of-the-jewel-study
#16
RANDOMIZED CONTROLLED TRIAL
Itaru Miura, Fumiya Sano, Reiko Sakaguchi, Keisuke Okamoto, Hidenori Maruyama
Objective: To evaluate the effects of lurasidone on social functioning in schizophrenia over the course of a 6-week, double-blind, placebo-controlled study and a subsequent 12-week open-label extension study. Methods: A total of 478 patients with schizophrenia (per DSM-IV-TR criteria) randomized to either lurasidone 40 mg/d (n = 245) or placebo (n = 233) in the initial 6-week double-blind study (initiated May 2016, completed November 2018) were included in the analysis. Longer-term changes were examined in a sample of 146 patients who received lurasidone, and 141 who received placebo, during the 6-week study and received flexibly dosed (40-80 mg/d) lurasidone during the 12-week extension phase...
January 31, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38301185/where-does-lamotrigine-fit-in-the-pharmacotherapy-of-mood-disorders-an-evidence-based-appraisal
#17
JOURNAL ARTICLE
Joseph F Goldberg
No abstract text is available yet for this article.
January 31, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38301190/physical-exercise-and-health-5-sedentary-time-independent-of-health-related-physical-activity-as-a-risk-factor-for-adverse-physical-health-and-mental-health-outcomes
#18
JOURNAL ARTICLE
Chittaranjan Andrade
Medical and neuropsychiatric benefits associated with physical exercise and activity are well recognized. It is less well known that time spent in sedentary behaviors, such as television-viewing or sitting at a desk, are associated with adverse health outcomes even after taking into consideration health-related physical activity. Although sedentary behaviors have become common in daily life, people tend to substantially underestimate how sedentary they actually are. The average person spends nearly 10 hours per day in a sedentary state, during leisure activities or work; sedentariness is even greater in persons with major mental illness such as psychosis...
January 29, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38301189/telehealth-collaborative-care-led-by-clinical-pharmacists-for-people-with-psychosis-or-bipolar-disorder-a-propensity-weighted-comparison-with-usual-psychiatric-care
#19
JOURNAL ARTICLE
Esti Iturralde, Lisa Fazzolari, Natalie E Slama, Stacey E Alexeeff, Stacy A Sterling, Sameer Awsare, Maria T Koshy, Macy Shia
Objective: People with psychosis or bipolar disorder (severe and persistent mental illness [SPMI]) are at high risk for poor psychiatric and chronic illness outcomes, which could be ameliorated through improved health care quality. This study assessed whether a telehealth, collaborative care program managed by psychiatric clinical pharmacists (SPMI Population Care) was associated with improved health care quality for adults with SPMI in a large California health system. Methods: This retrospective cohort study used electronic health record data to compare 968 program enrollees at 6 demonstration sites (Population Care) to 8,339 contemporaneous patients with SPMI at 6 non-program sites (Usual Care)...
January 29, 2024: Journal of Clinical Psychiatry
https://read.qxmd.com/read/38270545/the-clinician-s-tardive-inventory-cti-a-new-clinical-tool-for-documenting-and-rating-tardive-dyskinesia
#20
JOURNAL ARTICLE
Richard M Trosch, Cynthia L Comella, Stanley N Caroff, William G Ondo, Alicia C Shillington, Brandon J LaChappelle, Robert A Hauser, Christoph U Correll, Joseph H Friedman
Objective: Current clinician-rated tardive dyskinesia (TD) symptom scales have not addressed the expanding clinical signs and functional impact of TD. The study objective was to develop and test the reliability of a new integrated instrument. Methods: A movement disorder neurologist devised the outline of the rating scale. A Steering Committee (5 neurologists and 2 psychiatrists) provided revisions until consensus was reached. The Clinician's Tardive Inventory (CTI) assesses abnormal movements of the eye/eyelid/face, tongue/mouth, jaw, and limb/trunk; complex movements defined as complicated movements different from simple patterned movements or postures; and vocalizations...
January 24, 2024: Journal of Clinical Psychiatry
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