Megan A Rech, Brett A Faine, Alan E Gross, Priyanka Vakkalanka, Caitlin S Brown, Stephanie J Harding, Giles Slocum, David Zimmerman, Anne Zepeski, Stacey Rewitzer, Gavin T Howington, Matt Campbell, Jordan Dawson, Cierra N Treu, Lucas Nelson, Mandy Jones, Tara Flack, Blake Porter, Preeyaporn Sarangarm, Alicia E Mattson, Abby Bailey, Gregory Kelly, David A Talan
BACKGROUND: Urinary tract infections (UTIs) are commonly treated in the emergency department (ED), and unfortunately, resistance to first-line agents is increasing. OBJECTIVES: To characterize treatment of pyelonephritis in a nationally representative sample of ED patients and to identify patient- and treatment-specific factors associated with receiving initial inactive antibiotics. METHODS: We conducted a multicentre, observational cohort study utilizing the Emergency Medicine PHARMacotherapy Research NETwork (EMPHARM-NET), comprising 15 geographically diverse US EDs...
March 14, 2024: Journal of Antimicrobial Chemotherapy