Kohei Sunoki, Yoji Otsuka, Hidetaka Iwai, Tatsuya Nagano, Naoyuki Taga, Masaaki Kawada, Mamoru Takeuchi
With the surgical improvement of congenital heart disease, Fontan operation has been applied to many complicated patients in recent years. This is the first report of a child with panhypopituitarism who underwent Fontan operation. A 5-year-old boy was scheduled for Fontan operation. He previously underwent Blalock-Taussig shunt and bidirectional Glenn operations for univentricular heart with double-outlet right ventricle and pulmonary atresia. He was receiving hydrocortisone and 1-desamino-8-D-arginine vasopressin (DDAVP) for panhypopituitarism secondary to removal of craniopharyngioma performed at the age of three years...
January 15, 2021: Journal of Anesthesia
Joseph D Tobias
Like morphine, methadone is a pure agonist at the µ opioid receptor. However, in distinction to morphine which has an elimination half-life of 2-3 h, methadone has an elimination half-life of 24-36 h. In addition to its effects at the µ opioid receptor, methadone is an antagonist at the N-methyl-D-aspartate (NMDA) receptor and also inhibits the reuptake of the neurotransmitters, serotonin and norepinephrine, in the central nervous system. Given its long half-life and high oral bioavailability, methadone has had a primary role in the outpatient treatment of patients with a history of opioid abuse or addiction...
January 12, 2021: Journal of Anesthesia
Takashi Juri, Koichi Suehiro, Akihiro Uchimoto, Hirofumi Go, Yohei Fujimoto, Takashi Mori, Kiyonobu Nishikawa
PURPOSE: Invasive arterial blood pressure (IAP) and noninvasive blood pressure (NIBP) measurements are both common methods. Recently, a new method of error grid analysis was proposed to compare blood pressure obtained using two measurement methods. This study aimed to compare IAP and NIBP measurements using the error grid analysis and investigate potential confounding factors affecting the discrepancies between IAP and NIBP. METHODS: Adult patients who underwent general anesthesia in the supine position with both IAP and NIBP measurements were retrospectively investigated...
January 11, 2021: Journal of Anesthesia
Tatsuo Horiuchi, Tomonori Takazawa, Masaki Orihara, Shinya Sakamoto, Kazuhiro Nagumo, Shigeru Saito
Since perioperative anaphylaxis occurs suddenly, and it can be life-threatening, anesthesiologists need to have sufficient knowledge of the epidemiology of perioperative anaphylaxis and appropriate coping strategies to deal with it. Recent studies conducted in Western countries reported the characteristics of perioperative anaphylaxis in each country. However, there are few studies of perioperative anaphylaxis in Japan. To bridge the gap between Japan and other countries, the data of 46 anaphylaxis patients at Gunma University Hospital and 13 neighboring hospitals between 2012 and 2018 were collected and analyzed...
January 9, 2021: Journal of Anesthesia
Kosuke Hamada, Kazunobu Takahashi, Yasuyuki Tokinaga, Soshi Iwasaki, Michiaki Yamakage
PURPOSE: Rocuronium-induced injection pain often causes withdrawal movements leading to accidental disruption of indwelling needles. Generic rocuronium (Maruishi Pharmaceutical Co., Ltd, Osaka, Japan) with a novel solution has been reported to reduce the injection pain compared to original rocuronium [Esmeron® (Eslax® ), MSD Co. Ltd, Tokyo, Japan], however, no reports have compared the injection pain under sedation with propofol, the most frequently used general anesthetic. This study was carried out to compare the injection pain caused by generic rocuronium and that caused by original rocuronium in patients anesthetized by propofol with a target-controlled infusion system...
January 9, 2021: Journal of Anesthesia
Yuki Aoyama, Shinichi Sakura, Akiko Kitajo, Yoji Saito
BACKGROUND: Continuous interscalene brachial plexus block (CISB) provides analgesia after shoulder surgery. However, even a catheter securely fixed at the insertion site may be susceptible to migration, precluding the block from working consistently. We examined to see if catheter tip migration would occur with no catheter-at-skin change after anterior and posterior approaches to CISB in patients undergoing shoulder surgery, and compared the incidence rate and pain scores between approaches and between catheters with and without tip migration, respectively...
January 8, 2021: Journal of Anesthesia
Takahiro Tamura, Atsushi Mori, Kimitoshi Nishiwaki
No abstract text is available yet for this article.
January 8, 2021: Journal of Anesthesia
Guillermo Lema
No abstract text is available yet for this article.
January 7, 2021: Journal of Anesthesia
Bo Rim Kim, Susie Yoon, Gyu Young Song, Seohee Lee, Jae-Hyon Bahk, Karam Nam
PURPOSE: The effect of anesthetic types on postoperative acute kidney injury (AKI) remains unclear particularly in patients undergoing non-cardiac surgery. The purpose of this retrospective study was to compare total intravenous anesthesia (TIVA) and inhalation anesthesia in terms of the risk of AKI after open major abdominal surgery (MAS). METHODS: Adult patients who underwent open MAS (gastrectomy, hepatectomy, colectomy, or pancreatectomy) at our institute from 2016 to 2018 were included...
January 2, 2021: Journal of Anesthesia
Atsushi Yamashita, Tamie Takenami, Mariko Kawabata, Takahiro Honda
We report an 83-year-old man with myasthenia gravis (MG) who developed respiratory depression after spinal anesthesia for transurethral laser enucleation of the prostate. He became less responsive after complained of dyspnea, with a decrease of SpO2 to 83% approximately 13 min after intrathecal administration of 0.5% isobaric bupivacaine 3 ml. With a diagnosis of exacerbation of MG, hydrocortisone 100 mg was administered, following which both consciousness and spontaneous respiration rapidly improved. Cold sense was observed below the C4 dermatome...
January 2, 2021: Journal of Anesthesia
Hirotsugu Miyoshi, Takahiro Kato, Ryuji Nakamura, Noboru Saeki, Yuko Noda, Satoshi Kamiya, Atsushi Morio, Yasuo M Tsutsumi
BACKGROUND: We compared the pharmacokinetics of levobupivacaine when administered intraperitoneally, subcutaneously, and intravenously in an anesthetized rat model, to estimate the toxicity risk of a local anesthetic when absorbed from the peritoneum. METHODS: Thirty-two rats were anesthetized with sevoflurane. In Experiment 1, we administered 5.0 mg/kg of levobupivacaine intraperitoneally (IP) (n = 7), subcutaneously (SC) (n = 6), or intravenously (IV) (n = 6)...
January 1, 2021: Journal of Anesthesia
Daniele Bonvicini, Rafael Boscolo-Berto, Alessandro De Cassai, Michele Negrello, Veronica Macchi, Ivo Tiberio, Annalisa Boscolo, Raffaele De Caro, Andrea Porzionato
PURPOSE: Erector spinae plane (ESP) block is an interfascial blockade used in different clinical scenarios. This study investigated the ventral extent of dye diffusion in ESP block. METHODS: The ultrasound-guided ESP block was bilaterally performed with an injection at the T5 vertebral level (21-Gauge, 50 mm needle), using diluted black tissue marking dye (20 mL; 1:4 ratio with standard saline solution) instead of local anesthetic on two fresh-frozen corpses within the body donation program of the University of Padova...
December 19, 2020: Journal of Anesthesia
Michiaki Yamakage
No abstract text is available yet for this article.
December 15, 2020: Journal of Anesthesia
Takashi Asai
No abstract text is available yet for this article.
December 11, 2020: Journal of Anesthesia
Manabu Saito, Kazuhiko Nakamura, Kazuyoshi Hirota
No abstract text is available yet for this article.
November 24, 2020: Journal of Anesthesia
Yulim Lee, Ann Misun Youn, Xianshu Ju, Jianchen Cui, Boohwi Hong, Sangwon Yun, Youngkwon Ko, Yoon Hee Kim, Jun Young Heo, Woosuk Chung
PURPOSE: Measuring the neurotoxic effects of multiple anesthetic exposures during neurodevelopment is complex due to the numerous factors that can affect the outcome. While we recently discovered that the interval between multiple sevoflurane exposures can affect the level of neurotoxicity, the significance of interval for other anesthetic agents is unknown. Thus, we evaluated the significance of dosing interval in the neurotoxic effects of multiple ketamine injections in postnatal day (PND) 17 mice...
November 24, 2020: Journal of Anesthesia
Danny Mireault, Thomas R Cawthorn, Anna R Todd, Adam O Spencer
​PURPOSE: Suprazygomatic maxillary nerve blocks (SMB) are used in adult and pediatric patients to provide analgesia for midface surgery and chronic maxillofacial pain syndromes. The ultrasound-guided SMB technique ensures visualisation of the needle tip, avoidance of the maxillary artery and confirmation of local anesthetic spread. The goal of this study was to correctly identify SMB sonoanatomical landmarks to ensure the nerve block is performed safely and effectively. METHODS: Following an ultrasound-guided SMB with dye injection on 2 embalmed cadavers, pre-tragal face-lift style incision with a full thickness flap dissection was performed allowing accurate visualization of the bony landmarks being used for sonography and identification of the location of the injected dye...
November 23, 2020: Journal of Anesthesia
Tomoyuki Saito, Takashi Asai
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), is highly contagious. To protect healthcare workers from infection during airway management, some expert recommendations and guidelines recommended wearing P2/N95 masks, goggles or glasses, glove, face-shields, and gowns as standard personal protective equipment (PPE). Nevertheless, several simulation studies have suggested that the standard PPE may not fully protect healthcare workers. Dr. Hsien Yung Lai introduced an acrylic box ("aerosol box") as a part of PPE during airway management...
November 23, 2020: Journal of Anesthesia
Yusaku Terada, Tetsuya Miyashita, Yusuke Nagamine, Takahisa Goto
To avoid the risk of R-on-T incident and the unnecessary decrease of cardiac output, we devised an algorithm consisting of six steps for choosing the most appropriate intraoperative pacemaker (PM) mode, which is modified from Heart Rhythm Society and the American Society of Anesthesiologists expert consensus statement. Following this algorithm, we reviewed previous operations at our hospital to evaluate the appropriateness of the choices. Six of 78 cases (7.7%) were unfit to the algorithm because of an inappropriate mode change...
November 22, 2020: Journal of Anesthesia
Joungmin Kim, Hyung-Seok Kim, Minji Kim, Hong-Beom Bae, Jeong-Il Choi
PURPOSE: Many studies have been published on the beneficial effects of oral carbohydrate solutions (OCS) administered prior to surgery. However, the risk of pulmonary aspiration cannot be excluded in all patients undergoing anesthesia. But, there are few studies on the safety of OCS at lung aspiration. METHODS: Experiments were conducted with mice (Nine- to ten-week-old male BALB/c mice weighted 23-26 g). Lung aspiration was performed by intratracheal administration of OCS and its major constituents, fructose and maltodextrin...
November 22, 2020: Journal of Anesthesia
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