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Federico M Asch, Paul A Grayburn, Robert J Siegel, Saibal Kar, D Scott Lim, Jonathan G Zaroff, Jacob M Mishell, Brian Whisenant, Michael J Mack, JoAnn Lindenfeld, William T Abraham, Gregg W Stone, Neil J Weissman
BACKGROUND: In the COAPT trial among patients with heart failure (HF) and moderate-to-severe (3+) or severe (4+) secondary mitral regurgitation (SMR), patients treated with the transcatheter mitral valve replacement (TMVR) had reduced rates of HF hospitalization and mortality compared with guideline-directed medical therapy (GDMT) alone. OBJECTIVES: To describe the echocardiographic patient qualification process for COAPT, baseline echocardiographic characteristics, changes over time, and the interaction between treatment group and echocardiographic parameters on clinical outcomes...
September 28, 2019: Journal of the American College of Cardiology
#2
EDITORIAL
Mohamad Alkhouli, John J Lopez, Verghese Mathew
No abstract text is available yet for this article.
September 24, 2019: Journal of the American College of Cardiology
#3
Maurizio Taramasso, Giovanni Benfari, Pieter van der Bijl, Hannes Alessandrini, Adrian Attinger-Toller, Luigi Biasco, Philipp Lurz, Daniel Braun, Eric Brochet, Kim A Connelly, Sabine de Bruijn, Paolo Denti, Florian Deuschl, Rodrigo Estevez-Loureiro, Neil Fam, Christian Frerker, Mara Gavazzoni, Jo Rg Hausleiter, Edwin Ho, Jean-Michel Juliard, Ryan Kaple, Christian Besler, Susheel Kodali, Felix Kreidel, Karl-Heinz Kuck, Azeem Latib, Alexander Lauten, Vanessa Monivas, Michael Mehr, Guillem Muntané-Carol, Tamin Nazif, Georg Nickening, Giovanni Pedrazzini, François Philippon, Alberto Pozzoli, Fabien Praz, Rishi Puri, Josep Rodés-Cabau, Ulrich Scha Fer, Joachim Schofer, Horst Sievert, Gilbert H L Tang, Holger Thiele, Yan Topilsky, Karl-Philipp Rommel, Victoria Delgado, Alec Vahanian, Ralph Stephan Von Bardeleben, John G Webb, Marcel Weber, Stephan Windecker, Mirjam Winkel, Michel Zuber, Martin B Leon, Rebecca T Hahn, Jeroen J Bax, Maurice Enriquez-Sarano, Francesco Maisano
BACKGROUND: Tricuspid Regurgitation (TR) is associated with increased rates of heart failure (HF) and mortality. Transcatheter tricuspid valve interventions (TTVI) are promising, but the clinical benefit is unknown. OBJECTIVES: To investigate the potential benefit of TTVI over medical therapy in a propensity score matched population. METHODS: The TriValve (Transcatheter Tricuspid Valve Therapies) registry collected 472 patients from 22 European and North American centers, who underwent TTVI from 2016 to 2018...
September 24, 2019: Journal of the American College of Cardiology
#4
EDITORIAL
Saif Anwaruddin, Nimesh D Desai
No abstract text is available yet for this article.
September 23, 2019: Journal of the American College of Cardiology
#5
EDITORIAL
Charles D Resor
No abstract text is available yet for this article.
September 20, 2019: Journal of the American College of Cardiology
#6
Wieneke Vlastra, Jaya Chandrasekhar, Bruno García Del Blanco, Didier Tchétché, Fabio S de Brito, Marco Barbanti, Ran Kornowski, Azeem Latib, Augusto D'Onofrio, Flavio Ribichini, Jan Baan, Jan G P Tijssen, Raul Moreno, Nicolas Dumonteil, Flavio Tarasoutchi, Samantha Sartori, Paola D'Errigo, Giuseppe Tarantini, Mattia Lunardi, Katia Orvin, Matteo Pagnesi, Alberto Berenguer, Thomas Modine, George Dangas, Roxana Mehran, Jan J Piek, Ronak Delewi
BACKGROUND: Transfemoral aortic valve replacement (TAVR) is a guideline-recommended treatment option for patients with severe aortic valve stenosis. Females and males present with different baseline characteristics, which may influence procedural outcomes. OBJECTIVES: To evaluate differences between females and males undergoing transfemoral TAVR across the globe during the last decade. METHODS: The CENTER collaboration was a global patient level dataset of patients undergoing transfemoral TAVR (N= 12,381) from 2007-2018...
September 20, 2019: Journal of the American College of Cardiology
#7
Adnan K Chhatriwalla, Sreekanth Vemulapalli, Molly Szerlip, Susheel Kodali, Rebecca T Hahn, John T Saxon, Michael J Mack, Gorav Ailawadi, Jennifer Rymer, Pratik Manandhar, Andrzej S Kosinski, Paul Sorajja
BACKGROUND: Transcatheter mitral valve repair (TMVr) for the treatment of mitral regurgitation (MR) is a complex procedure that requires development of a unique skillset. OBJECTIVE: To examine the relationship between operator experience and procedural results of TMVr with MitraClip (Abbott Structural, Santa Clara, CA). METHODS: TMVr device procedures from the STS/ACC TVT Registry were analyzed with operator case number as a continuous and categorical (1-25, 26-50, and >50) variable...
September 19, 2019: Journal of the American College of Cardiology
#8
Suzanne J Baron, Elizabeth A Magnuson, Michael Lu, Kaijun Wang, Khaja Chinnakondepalli, Michael Mack, Vinod H Thourani, Susheel Kodali, Raj Makkar, Howard C Herrmann, Samir Kapadia, Vasilis Babaliaros, Mathew R Williams, Dean Kereiakes, Alan Zajarias, Maria C Alu, John G Webb, Craig R Smith, Martin B Leon, David J Cohen
BACKGROUND: In patients with severe aortic stenosis (AS) at low surgical risk, treatment with transcatheter aortic valve replacement (TAVR) results in lower rates of death, stroke, and re-hospitalization at 1 year compared with surgical aortic valve replacement; however, the effect of treatment strategy on health status is unknown. OBJECTIVES: This study sought to compare health status outcomes of TAVR vs. surgery in low-risk patients with severe AS. METHODS: Between 3/2016 and 10/2017, 1000 low-risk AS patients were randomized to transfemoral TAVR using a balloon-expandable valve or surgery in the PARTNER 3 Trial...
September 18, 2019: Journal of the American College of Cardiology
#9
LETTER
Giuseppe Maglietta, Maddalena Ardissino, Guidantonio Malagoli Tagliazucchi, Caterina Disisto, Piera Angelica Merlini, Antonio Crocamo, Maria Francesca Notarangelo, Paolo Calabrò, Carlo Berzuini, Diego Ardissino
No abstract text is available yet for this article.
August 23, 2019: Journal of the American College of Cardiology
#10
Yutao Guo, Hao Wang, Hui Zhang, Tong Liu, Zhaoguang Liang, Yunlong Xia, Li Yan, Yunli Xing, Haili Shi, Shuyan Li, Yanxia Liu, Fan Liu, Mei Feng, Yundai Chen, Gregory Y H Lip
BACKGROUND: Low detection and nonadherence are major problems in current management approaches for patients with suspected atrial fibrillation (AF). Mobile health (mHealth) devices may enable earlier AF detection, and improved AF management. OBJECTIVES: To investigate the effectiveness of AF screening in a large population-based cohort using smart device based photoplethysmography (PPG) technology, combined with a clinical care AF management pathway using a mHealth approach...
August 22, 2019: Journal of the American College of Cardiology
#11
Konstantinos C Koskinas, Stephan Windecker, Giovanni Pedrazzini, Christian Mueller, Stéphane Cook, Christian M Matter, Olivier Muller, Jonas Häner, Baris Gencer, Carmela Crljenica, Poorya Amini, Olga Deckarm, Juan F Iglesias, Lorenz Räber, Dik Heg, François Mach
BACKGROUND: While guidelines recommend in-hospital initiation of high-intensity statin therapy in patients with acute coronary syndromes (ACS), low-density lipoprotein cholesterol (LDL-C) target levels are frequently not attained. Evolocumab, a rapidly acting, potent LDL-C-lowering drug, has not been studied in the acute phase of ACS. OBJECTIVES: To assess the feasibility, safety, and LDL-C lowering efficacy of evolocumab initiated during the in-hospital phase of ACS...
August 16, 2019: Journal of the American College of Cardiology
#12
LETTER
Arman Qamar, Elliott M Antman, Robert P Giugliano
No abstract text is available yet for this article.
November 12, 2019: Journal of the American College of Cardiology
#13
LETTER
Pasquale Pignatelli, Daniele Pastori, Francesco Violi
No abstract text is available yet for this article.
November 12, 2019: Journal of the American College of Cardiology
#14
LETTER
Anders Dahl, Kasper Iversen, Emil Fosbol, Sandra Chamat, Niels E Bruun
No abstract text is available yet for this article.
November 12, 2019: Journal of the American College of Cardiology
#15
LETTER
Xianshi Zhou, Guanghua Tang
No abstract text is available yet for this article.
November 12, 2019: Journal of the American College of Cardiology
#16
LETTER
John E Madias
No abstract text is available yet for this article.
November 12, 2019: Journal of the American College of Cardiology
#17
LETTER
Gregory Y H Lip, Deepak L Bhatt, Stefan H Hohnloser, Takeshi Kimura, Corinna Miede, Matias Nordaby, Jonas Oldgren, Philippe Gabriel Steg, Jurriën M Ten Berg, Christopher P Cannon
No abstract text is available yet for this article.
November 12, 2019: Journal of the American College of Cardiology
#18
EDITORIAL
Ty J Gluckman, Lynne W Stevenson, Richard Kovacs
No abstract text is available yet for this article.
November 12, 2019: Journal of the American College of Cardiology
#19
Samuel S Gidding, Paul K Whelton, Robert M Carey, Glenn N Levine
No abstract text is available yet for this article.
November 12, 2019: Journal of the American College of Cardiology
#20
REVIEW
Zachary D Goldberger, Bradley J Petek, Michele Brignole, Win-Kuang Shen, Robert S Sheldon, Monica Solbiati, Jean-Claude Deharo, Angel Moya, Mohamed H Hamdan
Syncope is a commonly encountered and challenging problem in medical practice. Presentations are variable, and the causal mechanism often remains elusive even after extensive (and often expensive) evaluation. Clinical practice guidelines have been developed to help guide the multidisciplinary approach necessary to diagnose and manage the broad spectrum of patients presenting with syncope. The American College of Cardiology/American Heart Association, in collaboration with the Heart Rhythm Society, published its first syncope guidelines in 2017...
November 12, 2019: Journal of the American College of Cardiology
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