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Daisuke Matsubara, Hunter L Kauffman, Yan Wang, Renzo Calderon-Anyosa, Sumekala Nadaraj, Matthew D Elias, Travus J White, Deborah L Torowicz, Putri Yubbu, Therese M Giglia, Alexa N Hogarty, Joseph W Rossano, Michael D Quartermain, Anirban Banerjee
BACKGROUND: Centers from Europe and United States have reported an exceedingly high number of children with a severe inflammatory syndrome in the setting of COVID-19, which has been termed multisystem inflammatory syndrome in children (MIS-C). OBJECTIVES: This study aimed to analyze echocardiographic manifestations in MIS-C. METHODS: We retrospectively reviewed 28 MIS-C, 20 healthy controls and 20 classic Kawasaki disease (KD) patients. We reviewed echocardiographic parameters in acute phase of MIS-C and KD groups, and during subacute period in MIS-C group (interval: 5...
August 31, 2020: Journal of the American College of Cardiology
#2
EDITORIAL
Bruce D Gelb, Jane W Newburger, Amy E Roberts, Roberta G Williams
No abstract text is available yet for this article.
August 31, 2020: Journal of the American College of Cardiology
#3
Giuseppe Tarantini, Marco Mojoli, Ferdinando Varbella, Roberto Caporale, Stefano Rigattieri, Giuseppe Andò, Plinio Cirillo, Simona Pierini, Andrea Santarelli, Paolo Sganzerla, Luisa Cacciavillani, Luciano Babuin, Nicoletta De Cesare, Ugo Limbruno, Alberto Massoni, Andrea Rognoni, Daniela Pavan, Flavia Belloni, Carlo Cernetti, Luca Favero, Francesco Saia, Luca Nai Fovino, Giulia Masiero, Loris Roncon, Valeria Gasparetto, Marco Ferlini, Federico Ronco, Roberta Rossini, Paolo Canova, Daniela Trabattoni, Alessandra Russo, Vincenzo Guiducci, Carlo Penzo, Fabio Tarantino, Ciro Mauro, Elena Corrada, Giovanni Esposito, Sergio Berti, Matteo Martinato, Danila Azzolina, Dario Gregori, Dominick J Angiolillo, Giuseppe Musumeci
BACKGROUND: Although oral P2Y12 inhibitors are key in the management of patients with non-ST elevation acute coronary syndrome (NSTE-ACS), the optimal timing of their administration is not well defined. OBJECTIVE: to compare downstream and upstream oral P2Y12 inhibitors administration strategies in NSTE-ACS patients undergoing invasive management. METHODS: We performed a randomized, adaptive, open-label, multi-center, clinical trial. Patients were randomly assigned to receive pre-treatment with ticagrelor before angiography (upstream group) or no pre-treatment (downstream group)...
August 26, 2020: Journal of the American College of Cardiology
#4
Girish N Nadkarni, Anuradha Lala, Emilia Bagiella, Helena L Chang, Pedro Moreno, Elisabet Pujadas, Varun Arvind, Sonali Bose, Alexander W Charney, Martin D Chen, Carlos Cordon-Cardo, Andrew S Dunn, Michael E Farkouh, Benjamin Glicksberg, Arash Kia, Roopa Kohli-Seth, Matthew A Levin, Prem Timsina, Shan Zhao, Zahi A Fayad, Valentin Fuster
BACKGROUND: Thromboembolic disease is common in coronavirus disease-19 (COVID-19). There is limited evidence on association of in-hospital anticoagulation (AC) with outcomes and postmortem findings. OBJECTIVE: To examine association of AC with in-hospital outcomes and describe thromboembolic findings on autopsies. METHODS: A retrospective analysis examining association of AC with mortality, intubation and major bleeding. We also conducted sub-analyses on association of therapeutic vs prophylactic AC initiated ≤48 hours from admission...
August 24, 2020: Journal of the American College of Cardiology
#5
Johanne Silvain, Mathieu Kerneis, Michel Zeitouni, Benoit Lattuca, Sophie Galier, Delphine Brugier, Emilie Mertens, Niki Procopi, Gaspard Suc, Tomy Salloum, Eric Frisdal, Wilfried Le Goff, Jean-Philippe Collet, Eric Vicaut, Philippe Lesnik, Gilles Montalescot, Maryse Guerin
BACKGROUND: Inhibition of the interleukin-1β (IL-1β) innate immunity pathway is associated with anti-inflammatory effects and a reduced risk of recurrent cardiovascular events in stable patients with previous myocardial infarction (MI) and elevated high sensitivity C-reactive protein (hs-CRP). OBJECTIVES: to assess the association between IL-1β level with all-cause mortality in patients with acute ST segment elevation myocardial infarction (MI) undergoing primary percutaneous coronary intervention and the interplay between IL-1β and hs-CRP concentrations on the risk of premature death...
August 19, 2020: Journal of the American College of Cardiology
#6
Dingcheng Xiang, Xin Xiang, Wei Zhang, Shaodong Yi, Jinxia Zhang, Xiaolong Gu, Yawei Xu, Kai Huang, Xi Su, Bo Yu, Yan Wang, Weiyi Fang, Yong Huo, Junbo Ge
BACKGROUND: ST-segment elevation myocardial infarction (STEMI) is a fatal cardiovascular emergency requiring rapid reperfusion treatment. During the coronavirus disease-2019 (COVID-19) pandemic, medical professionals need to strike a balance between providing timely treatment for STEMI patients and implementing infection control procedures to prevent nosocomial spread of COVID-19 among health care workers and other vulnerable cardiovascular patients. OBJECTIVES: This study evaluates the impact of the COVID-19 outbreak and China Chest Pain Center's modified STEMI protocol on the treatment and prognosis of STEMI patients in China...
August 14, 2020: Journal of the American College of Cardiology
#7
EDITORIAL
Lauren S Ranard, Sahil A Parikh, Ajay J Kirtane
No abstract text is available yet for this article.
August 14, 2020: Journal of the American College of Cardiology
#8
LETTER
Ethan J Rowin, Barry J Maron, Martin S Maron
No abstract text is available yet for this article.
August 14, 2020: Journal of the American College of Cardiology
#9
LETTER
Chi Wang, Yu Yuan, Shouling Wu, Hao Xue
No abstract text is available yet for this article.
August 14, 2020: Journal of the American College of Cardiology
#10
LETTER
Hexuan Zhang, Zhigang Zhao, Hongbo He, Zhiming Zhu
No abstract text is available yet for this article.
August 14, 2020: Journal of the American College of Cardiology
#11
LETTER
Hashrul N Rashid, Robert P Gooley, James D Cameron
No abstract text is available yet for this article.
August 14, 2020: Journal of the American College of Cardiology
#12
LETTER
Jonathan R Dalzell, Eugene C Connolly, Jane A Cannon
No abstract text is available yet for this article.
August 14, 2020: Journal of the American College of Cardiology
#13
LETTER
Besola Laura, Cademartiri Filippo, Belluco Enrica, Gerosa Gino, Colli Andrea
No abstract text is available yet for this article.
August 14, 2020: Journal of the American College of Cardiology
#14
EDITORIAL
Javed Butler, Muhammad Shahzeb Khan
No abstract text is available yet for this article.
August 14, 2020: Journal of the American College of Cardiology
#15
LETTER
Mario Gaudino, Varun Arvind, Irbaz Hameed, Antonino Di Franco, Cristiano Spadaccio, Deepak L Bhatt, Emilia Bagiella
No abstract text is available yet for this article.
July 29, 2020: Journal of the American College of Cardiology
#16
EDITORIAL
Douglas P Zipes, Jagat Narula, Jeroen J Bax
No abstract text is available yet for this article.
July 28, 2020: Journal of the American College of Cardiology
#17
Jeffrey T Kuvin
No abstract text is available yet for this article.
July 27, 2020: Journal of the American College of Cardiology
#18
REVIEW
Lawrence Rudski, James L Januzzi, Vera H Rigolin, Erin A Bohula, Ron Blankstein, Amit R Patel, Chiara Bucciarelli-Ducci, Esther Vorovich, Monica Mukherjee, Sunil V Rao, Rob Beanlands, Todd C Villines, Marcelo F Di Carli
Standard evaluation and management of the patient with suspected or proven cardiovascular complications of COVID-19, the disease caused by severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2), is challenging. Routine history, physical examination, laboratory testing, electrocardiography and plain x-ray imaging may often suffice for such patients but given overlap between COVID-19 and typical cardiovascular diagnoses such as heart failure and acute myocardial infarction, need frequently arises for advanced imaging techniques to assist in differential diagnosis and management...
July 20, 2020: Journal of the American College of Cardiology
#19
LETTER
Stavros E Mountantonakis, Moussa Saleh, Kristie Coleman, Jeffrey Kuvin, Varinder Singh, Rajiv Jauhar, Lawrence Ong, Michael Qiu, Laurence M Epstein
No abstract text is available yet for this article.
July 11, 2020: Journal of the American College of Cardiology
#20
Fizzah A Choudry, Stephen M Hamshere, Krishnaraj S Rathod, Mohammad M Akhtar, R Andrew Archbold, Oliver P Guttmann, Simon Woldman, Ajay K Jain, Charles J Knight, Andreas Baumbach, Anthony Mathur, Daniel A Jones
BACKGROUND: Coronavirus disease 2019 (COVID-19) is thought to predispose patients to thrombotic disease. To date there are few reports of ST-elevation myocardial infarction (STEMI) caused by type 1 myocardial infarction in COVID-19 patients. OBJECTIVES: The aim of this study was to describe the demographic, angiographic, and procedural characteristics alongside clinical outcomes of consecutive cases of COVID-19 positive STEMI patients compared to COVID-19 negative patients...
July 10, 2020: Journal of the American College of Cardiology
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