Gregg W Stone, Ziad A Ali, Sean M O'Brien, Grace Rhodes, Philippe Genereux, Sripal Bangalore, Kreton Mavromatis, Jennifer Horst, Ovidiu Dressler, Kian Keong Poh, Ranjit K Nath, Nagaraja Moorthy, Adam Witkowski, Sudhanshu K Dwivedi, Olga Bockeria, Jiyan Chen, Paola E P Smanio, Michael H Picard, Bernard R Chaitman, Daniel S Berman, Leslee J Shaw, William E Boden, Harvey D White, Stephen E Fremes, Yves Rosenberg, Harmony R Reynolds, John A Spertus, Judith S Hochman, David J Maron
BACKGROUND: Anatomic complete revascularization (ACR) and functional complete revascularization (FCR) have been associated with reduced death and myocardial infarction (MI) in some prior studies. The impact of complete revascularization (CR) in patients undergoing an invasive (INV) compared with a conservative (CON) management strategy has not been reported. OBJECTIVES: Among patients with chronic coronary disease without prior coronary artery bypass grafting randomized to INV vs CON management in the ISCHEMIA (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches) trial, we examined the following: 1) the outcomes of ACR and FCR compared with incomplete revascularization; and 2) the potential impact of achieving CR in all INV patients compared with CON management...
July 11, 2023: Journal of the American College of Cardiology