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Satoshi Shoji, Toshiki Kuno, Tomohiro Fujisaki, Hisato Takagi, Alexandros Briasoulis, Pierre Deharo, Thomas Cuisset, Azeem Latib, Shun Kohsaka
BACKGROUND: Balancing the effects of dual antiplatelet therapy (DAPT) in the era of potent P2Y12 inhibitors has become a cornerstone of acute coronary syndrome (ACS) management. Recent randomized controlled trials (RCTs) have investigated DAPT de-escalation to decrease the risk of bleeding outcomes. OBJECTIVES: The aim of this study was to compare the efficacy and safety outcomes of various DAPT strategies in patients with ACS, including de-escalation from a potent P2Y12 inhibitor to clopidogrel or low-dose prasugrel...
July 9, 2021: Journal of the American College of Cardiology
#2
Laxmi S Mehta, Mitchell S V Elkind, Stephan Achenbach, Fausto J Pinto, Athena Poppas
No abstract text is available yet for this article.
July 7, 2021: Journal of the American College of Cardiology
#3
LETTER
Alessandro Di Toro, Mario Urtis, Lorenzo Giuliani, Carlo Pellegrini, Alexandra Smirnova, Raffaele Galato, Adele Valentini, Hussein Jallous, Sergio Scaccabarozzi, Eloisa Arbustini
No abstract text is available yet for this article.
July 6, 2021: Journal of the American College of Cardiology
#4
Behnood Bikdeli, Saurav Chatterjee, Shilpkumar Arora, Manuel Monreal, David Jimenez, Harlan M Krumholz, Samuel Z Goldhaber, Mitchell S V Elkind, Gregory Piazza
No abstract text is available yet for this article.
June 2, 2021: Journal of the American College of Cardiology
#5
EDITORIAL
Subodh Verma, David A Latter, Robert O Bonow
No abstract text is available yet for this article.
May 21, 2021: Journal of the American College of Cardiology
#6
Jeffrey Willett, Stephan Achenbach, Fausto J Pinto, Athena Poppas, Mitchell S V Elkind
No abstract text is available yet for this article.
May 19, 2021: Journal of the American College of Cardiology
#7
Michael C Honigberg, Seyedeh M Zekavat, James P Pirruccello, Pradeep Natarajan, Muthiah Vaduganathan
BACKGROUND: Treatment guidelines for pre-diabetes primarily focus on glycemic control and lifestyle management. Few evidence-based cardiovascular and kidney risk-reduction strategies are available in this population. OBJECTIVES: To characterize cardiovascular and kidney outcomes across the glycemic spectrum. METHODS: Among participants in the UK Biobank without prevalent type 1 diabetes, cardiovascular, or kidney disease, Cox models tested the association of glycemic exposures (type 2 diabetes [T2D], pre-diabetes, normoglycemia) with outcomes (ASCVD, chronic kidney disease [CKD], and heart failure), adjusting for demographic, lifestyle, and cardiometabolic risk factors...
May 11, 2021: Journal of the American College of Cardiology
#8
Rupert M Bauersachs, Michael Szarek, Marianne Brodmann, Ivan Gudz, Eike Sebastian Debus, Mark R Nehler, Sonia S Anand, Manesh R Patel, Connie N Hess, Warren H Capell, Kevin Rogers, Eva Muehlhofer, Lloyd P Haskell, Scott D Berkowitz, William R Hiatt, Marc P Bonaca
BACKGROUND: Patients with peripheral artery disease (PAD) undergoing lower extremity revascularization (LER) are at high risk of major adverse limb and cardiovascular events. VOYAGER PAD demonstrated that rivaroxaban 2.5 mg twice daily reduced first events by 15%. The benefit of rivaroxaban on total (first and subsequent) events in this population is unknown. OBJECTIVES: To evaluate the total burden of vascular events in PAD patients after LER and the efficacy of low dose rivaroxaban on total events...
May 7, 2021: Journal of the American College of Cardiology
#9
Associations of Cardiac Mechanics with Exercise Capacity: The Multi-Ethnic Study of Atherosclerosis.
Ravi B Patel, Benjamin H Freed, Lauren Beussink-Nelson, Norrina B Allen, Suma H Konety, Wendy S Post, Joseph Yeboah, Dalane W Kitzman, Alain G Bertoni, Sanjiv J Shah
BACKGROUND: Lower exercise capacity, as measured by 6-minute walk distance (6MWD), is associated with incident heart failure (HF). Among those without HF, the associations of measures of cardiac structure and function with 6MWD are unclear, and may provide insight regarding the risk of incident HF. OBJECTIVES: To understand the relationships between cardiac function and exercise capacity. METHODS: We evaluated the associations of cardiac mechanics with 6MWD in the 6th exam of the Multi-Ethnic Study of Atherosclerosis...
May 6, 2021: Journal of the American College of Cardiology
#10
Ivor J Benjamin, C Michael Valentine, William J Oetgen, Katherine A Sheehan, Ralph G Brindis, William H Roach, Robert A Harrington, Glenn N Levine, Rita F Redberg, Bernadette M Broccolo, Adrian F Hernandez, Pamela S Douglas, Ileana L Piña, Emelia J Benjamin, Megan J Coylewright, Jorge F Saucedo, Keith C Ferdinand, Sharonne N Hayes, Athena Poppas, Karen L Furie, Laxmi S Mehta, John P Erwin, Jennifer H Mieres, Daniel J Murphy, Gaby Weissman, Colin P West, Willie E Lawrence, Frederick A Masoudi, Camara P Jones, Daniel D Matlock, Jennifer E Miller, John A Spertus, Lynn Todman, Cathleen Biga, Richard A Chazal, Mark A Creager, Edward T Fry, Michael J Mack, Clyde W Yancy, Richard E Anderson
No abstract text is available yet for this article.
May 5, 2021: Journal of the American College of Cardiology
#11
EDITORIAL
Gerald V Naccarelli, Edward J Filippone, Andrew Foy
No abstract text is available yet for this article.
May 4, 2021: Journal of the American College of Cardiology
#12
Gerasimos Filippatos, George L Bakris, Bertram Pitt, Rajiv Agarwal, Peter Rossing, Luis M Ruilope, Javed Butler, Carolyn S P Lam, Peter Kolkhof, Luke Roberts, Christoph Tasto, Amer Joseph, Stefan D Anker
BACKGROUND: Patients with chronic kidney disease (CKD) and type 2 diabetes (T2D) are at risk of atrial fibrillation or flutter (AFF) due to cardiac remodeling and kidney complications. Finerenone, a novel, selective, nonsteroidal mineralocorticoid receptor antagonist, inhibited cardiac remodeling in preclinical models. OBJECTIVES: To examine the effect of finerenone on new-onset AFF and cardiorenal effects by history of AFF in FIDELIO-DKD. METHODS: Patients with CKD and T2D were randomized (1:1) to finerenone or placebo...
May 4, 2021: Journal of the American College of Cardiology
#13
EDITORIAL
João Pedro Ferreira
No abstract text is available yet for this article.
May 4, 2021: Journal of the American College of Cardiology
#14
LETTER
Matthew J Czarny, Sanjiv J Shah, Seamus P Whelton, Michael J Blaha, Michael Y Tsai, Rimsky Denis, Alain Bertoni, Wendy S Post
No abstract text is available yet for this article.
May 4, 2021: Journal of the American College of Cardiology
#15
Charles A Herzog, Mengistu A Simegn, Yifan Xu, Salvatore R Costa, Roy O Mathew, Mohammad C El-Hajjar, Sanjeev Gulati, Rafael A Maldonado, Eric Daugas, Magdelena Madero, Jerome L Fleg, Rebecca Anthopolos, Gregg W Stone, Mandeep S Sidhu, David J Maron, Judith S Hochman, Sripal Bangalore
BACKGROUND: Patients with chronic kidney disease (CKD) and coronary artery disease frequently undergo preemptive revascularization before kidney transplant listing. OBJECTIVES: In this post-hoc analysis from ISCHEMIA-CKD, we compared outcomes of patients not listed versus those listed according to management strategy. METHODS: In ISCHEMIA-CKD (n=777), 194 patients (25%) with chronic coronary syndromes and at least moderate ischemia were listed for transplant...
May 4, 2021: Journal of the American College of Cardiology
#16
LETTER
Noemi Pavo, Suriya Prausmüller, Philipp E Bartko, Georg Goliasch, Martin Hülsmann
No abstract text is available yet for this article.
August 3, 2021: Journal of the American College of Cardiology
#17
LETTER
Emilie De Hert, Ingrid De Meester
No abstract text is available yet for this article.
August 3, 2021: Journal of the American College of Cardiology
#18
LETTER
Anastasia Shchendrygina, Nathan Mewton, Anja Zupan Meznar
No abstract text is available yet for this article.
August 3, 2021: Journal of the American College of Cardiology
#19
LETTER
Edwyn O Cruz-López, Estrellita Uijl, A H Jan Danser
No abstract text is available yet for this article.
August 3, 2021: Journal of the American College of Cardiology
#20
LETTER
Li Li, Jingkun Wang, Guangfeng Zhao, Stephen Topaz, David Morales, Ajit Yoganathan, Cherry Ballard-Croft, Joseph B Zwischenberger, Dongfang Wang
No abstract text is available yet for this article.
August 3, 2021: Journal of the American College of Cardiology
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