Mika Ogata, Takanobu Yoshida, Jun Kido, Natsuko Nishi, Sachiko Shimomura, Nami Hirai, Masaaki Yanai, Tomoyuki Mizukami, Kimitoshi Nakamura
INTRODUCTION: During an oral food challenge (OFC), there is a risk of adverse reactions, including anaphylaxis. Therefore, the physician should carefully conduct the OFC. This study aimed to evaluate the OFC results in individuals with low levels of egg white (EW)- and ovomucoid (OVM)-specific immunoglobulin E (sIgE) and the safety of a hen's egg (HE) OFC in these individuals. METHODS: A total of 2,058 individuals with low EW- or OVM-sIgE underwent HE-OFC at two institutions in Kumamoto prefecture, located in the western area of Japan, between January 1, 2017, and December 31, 2021, within 1 year of recorded sIgE measurements...
September 19, 2023: International Archives of Allergy and Immunology