journal
https://read.qxmd.com/read/33452123/long-term-survival-benefit-of-ramipril-in-patients-with-acute-myocardial-infarction-complicated-by-heart-failure
#1
Jianhua Wu, Alistair S Hall, Chris P Gale
AIMS: ACE inhibition reduces mortality and morbidity in patients with heart failure after acute myocardial infarction (AMI). However, there are limited randomised data about the long-term survival benefits of ACE inhibition in this population. METHODS: In 1993, the Acute Infarction Ramipril Efficacy (AIRE) study randomly allocated patients with AMI and clinical heart failure to ramipril or placebo. The duration of masked trial therapy in the UK cohort (603 patients, mean age=64...
January 15, 2021: Heart
https://read.qxmd.com/read/33452122/effusive-constrictive-pericarditis-in-the-spectrum-of-pericardial-compressive-syndromes
#2
REVIEW
Scott E Janus, Brian D Hoit
When pericardial fluid accumulates and exceed the reserve volume of the pericardium or when the pericardium becomes scarred and inelastic, one of three pericardial compressive syndromes may ensue, namely, cardiac tamponade (CT), characterised by the accumulation of pericardial fluid under pressure; constrictive pericarditis (CP), the result of scarring and loss of the normal elasticity of the pericardial sac; and effusive-constrictive pericarditis (ECP), characterised by the concurrence of a tense pericardial effusion and constriction of the heart by the visceral pericardium...
January 15, 2021: Heart
https://read.qxmd.com/read/33452121/sacubitril-valsartan-in-the-treatment-of-systemic-right-ventricular-failure
#3
Tjitske E Zandstra, Marieke Nederend, Monique R M Jongbloed, Philippine Kiès, Hubert W Vliegen, Berto J Bouma, Laurens F Tops, Martin J Schalij, Anastasia D Egorova
OBJECTIVE: Pharmacological options for patients with a failing systemic right ventricle (RV) in the context of transposition of the great arteries (TGA) after atrial switch or congenitally corrected TGA (ccTGA) are not well defined. This study aims to investigate the feasibility and effects of sacubitril/valsartan treatment in a single-centre cohort of patients. METHODS: Data on all consecutive adult patients (n=20, mean age 46 years, 50% women) with a failing systemic RV in a biventricular circulation treated with sacubitril/valsartan in our centre are reported...
January 15, 2021: Heart
https://read.qxmd.com/read/33452120/cochrane-corner-physical-activity-interventions-for-people-with-congenital-heart-disease
#4
Curtis A Wadey, Guido Pieles, Graham Stuart, Rod Taylor, Linda Long, Craig A Williams
No abstract text is available yet for this article.
January 15, 2021: Heart
https://read.qxmd.com/read/33452119/microvascular-obstruction-time-to-bust-the-clot-hypothesis
#5
EDITORIAL
Sean Coffey, Philip D Adamson
No abstract text is available yet for this article.
January 15, 2021: Heart
https://read.qxmd.com/read/33452118/risk-of-out-of-hospital-cardiac-arrest-in-patients-with-bipolar-disorder-or-schizophrenia
#6
Carlo Alberto Barcella, Grimur Mohr, Kristian Kragholm, Daniel Christensen, Thomas A Gerds, Christoffer Polcwiartek, Mads Wissenberg, Casper Bang, Fredrik Folke, Christian Torp-Pedersen, Lars Vedel Kessing, Gunnar Hilmar Gislason, Kathrine Bach Søndergaard
OBJECTIVE: Patients with bipolar disorder and schizophrenia are at high cardiovascular risk; yet, the risk of out-of-hospital cardiac arrest (OHCA) compared with the general population remains scarcely investigated. METHODS: We conducted a nested case-control study using Cox regression to assess the association of bipolar disorder and schizophrenia with the HRs of OHCA of presumed cardiac cause (2001-2015). Reported are the HRs with 95% CIs overall and in subgroups defined by established cardiac disease, cardiovascular risk factors and psychotropic drugs...
January 15, 2021: Heart
https://read.qxmd.com/read/33452117/pregnancy-with-coarctation-appears-low-risk-overall-but-individual-cardiovascular-evaluation-remains-essential
#7
EDITORIAL
Rachael Cordina, Wei Li
No abstract text is available yet for this article.
January 15, 2021: Heart
https://read.qxmd.com/read/33452116/socioeconomic-status-and-cardiovascular-health-in-the-covid-19-pandemic
#8
REVIEW
Jeremy Naylor-Wardle, Ben Rowland, Vijay Kunadian
The goals of this review are to evaluate the impact of socioeconomic (SE) status on the general health and cardiovascular health of individuals during the COVID-19 pandemic and also discuss the measures to address disparity. SE status is a strong predictor of premature morbidity and mortality within general health. A lower SE status also has implications of increased cardiovascular disease (CVD) mortality and poorer CVD risk factor profiles. CVD comorbidity is associated with a higher case severity and mortality rate from COVID-19, with both CVD and COVID-19 sharing important risk factors...
January 15, 2021: Heart
https://read.qxmd.com/read/33441371/out-of-the-woods-but-still-in-the-weeds-when-cancer-therapy-becomes-part-of-a-chronic-condition
#9
EDITORIAL
Kathleen W Zhang
No abstract text is available yet for this article.
January 13, 2021: Heart
https://read.qxmd.com/read/33436493/effect-of-coronary-flow-on-intracoronary-alteplase-a-prespecified-analysis-from-a-randomised-trial
#10
Annette Marie Maznyczka, Peter McCartney, Patrycja Duklas, Margaret McEntegart, Keith G Oldroyd, John P Greenwood, Douglas Muir, Saqib Chowdhary, Anthony H Gershlick, Clare Appleby, Hany Eteiba, James Cotton, Andrew Wragg, Nick Curzen, R Campbell Tait, Peter MacFarlane, Paul Welsh, Naveed Sattar, Mark C Petrie, Ian Ford, Keith A A Fox, Alex McConnachie, Colin Berry
OBJECTIVES: Persistently impaired culprit artery flow (<TIMI 3) during primary percutaneous coronary intervention is a surrogate for failed myocardial perfusion. We evaluated the effects of intracoronary alteplase according to TIMI flow grade immediately preceding drug administration. METHODS: In T-TIME (trial of low-dose adjunctive alTeplase during primary PCI), patients ≤6 hours from onset of ST-elevation myocardial infarction (STEMI) were randomised to placebo, alteplase 10 mg or alteplase 20 mg, administered by infusion into the culprit artery, pre-stenting...
January 12, 2021: Heart
https://read.qxmd.com/read/33436492/artificial-intelligence-and-the-promise-of-uplifting-echocardiography
#11
EDITORIAL
Erwan Donal, Denisa Muraru, Luigi Badano
No abstract text is available yet for this article.
January 12, 2021: Heart
https://read.qxmd.com/read/33436491/coronary-revascularisation-in-patients-with-ischaemic-cardiomyopathy
#12
REVIEW
Matthew Ryan, Holly Morgan, Mark C Petrie, Divaka Perera
Heart failure resulting from ischaemic heart disease is associated with a poor prognosis despite optimal medical treatment. Despite this, patients with ischaemic cardiomyopathy have been largely excluded from randomised trials of revascularisation in stable coronary artery disease. Revascularisation has multiple potential mechanisms of benefit, including the reversal of myocardial hibernation, suppression of ventricular arrhythmias and prevention of spontaneous myocardial infarction. Coronary artery bypass grafting is considered the first-line mode of revascularisation in these patients; however, evidence from the Surgical Treatment of Ischaemic Heart Failure (STICH) trial showed a reduction in mortality, though this only became apparent with extended follow-up due to an excess of early adverse events in the surgical arm...
January 12, 2021: Heart
https://read.qxmd.com/read/33436490/single-high-sensitivity-troponin-levels-to-assess-patients-with-potential-acute-coronary-syndromes
#13
Cara Barnes, Daniel M Fatovich, Stephen P J Macdonald, Richard F Alcock, Jon R Spiro, Tom G Briffa, Carl J Schultz, Graham S Hillis
OBJECTIVE: We tested the hypothesis that patients with a potential acute coronary syndrome (ACS) and very low levels of high-sensitivity cardiac troponin I can be efficiently and safely discharged from the emergency department after a single troponin measurement. METHODS: This prospective cohort study recruited 2255 consecutive patients aged ≥18 years presenting to the Emergency Department, Royal Perth Hospital, Western Australia, with chest pain without high-risk features but requiring the exclusion of ACS...
January 12, 2021: Heart
https://read.qxmd.com/read/33436489/female-trailblazers-and-role-models-in-procedure-based-cardiology
#14
Shrilla Banerjee, Natalia Briceno, Paul Hill, Harriet Hurrell, Irum Diamond Kotadia
No abstract text is available yet for this article.
January 12, 2021: Heart
https://read.qxmd.com/read/33436488/it-is-not-all-about-mortality
#15
LETTER
David Niederseer, Christian Schmied
No abstract text is available yet for this article.
January 12, 2021: Heart
https://read.qxmd.com/read/33431425/remote-monitoring-in-heart-failure-current-and-emerging-technologies-in-the-context-of-the-pandemic
#16
REVIEW
Donya Mohebali, Michelle M Kittleson
The incidence of heart failure (HF) remains high and patients with HF are at risk for frequent hospitalisations. Remote monitoring technologies may provide early indications of HF decompensation and potentially allow for optimisation of therapy to prevent HF hospitalisations. The need for reliable remote monitoring technology has never been greater as the COVID-19 pandemic has led to the rapid expansion of a new mode of healthcare delivery: the virtual visit. With the convergence of remote monitoring technologies and reliable method of remote healthcare delivery, an understanding of the role of both in the management of patients with HF is critical...
January 11, 2021: Heart
https://read.qxmd.com/read/33431424/sex-differences-in-heart-failure-hospitalisation-risk-following-acute-myocardial-infarction
#17
Srikanth Yandrapalli, Aaqib Malik, Gayatri Pemmasani, Wilbert Aronow, Falak Shah, Gregg Lanier, Howard Cooper, Diwakar Jain, Srihari Naidu, William Frishman, Julio Panza
OBJECTIVE: We evaluated the sex differences in 6-month heart failure (HF) hospitalisation risk in acute myocardial infarction (AMI) survivors. METHODS: For this retrospective cohort analysis, adult survivors of an AMI between January and June 2014 were identified from the US Nationwide Readmissions Database. The primary outcome was a HF hospitalisation within 6 months. Secondary outcomes were fatal HF hospitalisation and the composite of index in-hospital HF or 6-month HF hospitalisation...
January 11, 2021: Heart
https://read.qxmd.com/read/33431423/pregnancy-during-cardiology-training-a-call-to-action
#18
Sarah M Birkhoelzer, Francis J E Gardner, Rebecca F Ortega, Roxana Mehran
No abstract text is available yet for this article.
January 11, 2021: Heart
https://read.qxmd.com/read/33419884/survival-and-risk-of-recurrence-of-takotsubo-syndrome
#19
Christopher Lau, Sarah Chiu, Rohith Nayak, Bryan Lin, Ming-Sum Lee
OBJECTIVE: The goal of this study is to evaluate the long-term outcomes of patients with takotsubo syndrome and assess factors associated with death or recurrence. METHODS: This is a retrospective population-based cohort study of consecutive patients who presented to an integrated health system in Southern California with takotsubo syndrome between 2006 and 2016. Medical records were manually reviewed to confirm diagnosis and to identify predisposing factors, medication treatment and long-term outcomes...
January 8, 2021: Heart
https://read.qxmd.com/read/33419883/successful-resuscitation-of-sudden-cardiac-death-education-matters
#20
EDITORIAL
Alwin Noordman, Yuri Blaauw, Alexander H Maass
No abstract text is available yet for this article.
January 8, 2021: Heart
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