journal
https://read.qxmd.com/read/38960589/sudden-cardiac-arrest-in-patients-with-cancer-in-the-general-population-insights-from-the-paris-sdec-registry
#1
JOURNAL ARTICLE
Orianne Weizman, Assié Eslami, Wulfran Bougouin, Frankie Beganton, Lionel Lamhaut, Daniel Jost, Florence Dumas, Alain Cariou, Eloi Marijon, Xavier Jouven, Mariana Mirabel
BACKGROUND: Data on the management of patients with cancer presenting with sudden cardiac arrest (SCA) are scarce. We aimed to assess the characteristics and outcomes of SCA according to cancer history. METHODS: Prospective, population-based registry including every out-of-hospital SCA in adults in Paris and its suburbs, between 2011 and 2019, with a specific focus on patients with cancer. RESULTS: Out of 4069 patients who had SCA admitted alive in hospital, 207 (5...
July 2, 2024: Heart
https://read.qxmd.com/read/38960588/treatment-drop-in-in-a-contemporary-cohort-used-to-derive-cardiovascular-risk-prediction-equations
#2
JOURNAL ARTICLE
Jingyuan Liang, Rodney T Jackson, Romana Pylypchuk, Yeunhyang Choi, Claris Chung, Sue Crengle, Pei Gao, Corina Grey, Matire Harwood, Anders Holt, Andrew Kerr, Suneela Mehta, Susan Wells, Katrina Poppe
BACKGROUND: No routinely recommended cardiovascular disease (CVD) risk prediction equations have adjusted for CVD preventive medications initiated during follow-up (treatment drop-in) in their derivation cohorts. This will lead to underestimation of risk when equations are applied in clinical practice if treatment drop-in is common. We aimed to quantify the treatment drop-in in a large contemporary national cohort to determine whether equations are likely to require adjustment. METHODS: Eight de-identified individual-level national health administrative datasets in Aotearoa New Zealand were linked to establish a cohort of almost all New Zealanders without CVD and aged 30-74 years in 2006...
July 2, 2024: Heart
https://read.qxmd.com/read/38955394/revealing-the-hidden-threat-behind-detectable-cardiac-troponin-levels-in-the-emergency-department
#3
EDITORIAL
Maribel Gonzalez-Del-Hoyo, Alfredo Bardaji
No abstract text is available yet for this article.
July 1, 2024: Heart
https://read.qxmd.com/read/38955393/angiogram-derived-physiology-will-it-change-the-game-or-miss-the-boat
#4
EDITORIAL
Nick Curzen
No abstract text is available yet for this article.
July 1, 2024: Heart
https://read.qxmd.com/read/38944418/healthcare-utilisation-and-quality-of-life-according-to-atrial-fibrillation-burden-episode-frequency-and-duration
#5
JOURNAL ARTICLE
Maria Hee Jung Park Frausing, Martijn Van De Lande, Dominik Linz, Harry J G M Crijns, Robert G Tieleman, Martin E W Hemels, Mirko De Melis, Ulrich Schotten, Mads Brix Kronborg, Jens C Nielsen, Isabelle Van Gelder, Michiel Rienstra
BACKGROUND: We aimed to evaluate the association between atrial fibrillation (AF) burden, duration and number of episodes with healthcare utilisation and quality of life in patients with early paroxysmal AF without a history of AF. METHODS: In this observational cohort study, we included 417 patients with paroxysmal AF from the Reappraisal of Atrial Fibrillation: interaction between hyperCoagulability, Electrical remodelling and Vascular destabilisation in the progression of AF (RACE V) Study...
June 29, 2024: Heart
https://read.qxmd.com/read/38925882/age-stratified-patterns-in-clinical-presentation-treatment-and-outcomes-in-acute-pericarditis-a-retrospective-cohort-study
#6
JOURNAL ARTICLE
Valentino Collini, Luca Siega Vignut, Federico Angriman, Gioia Braidotti, Marzia De Biasio, Massimo Imazio
BACKGROUND: There are limited data on acute pericarditis according to different age groups. The aim of this study is to investigate the role of age-related features in clinical characteristics, management, and outcomes of acute pericarditis, with a focus on the geriatric population. METHODS: Patients with a first episode of acute pericarditis were consecutively enrolled between January 2014 and June 2022, and divided into four groups according to age (G1: 18-35 years; G2: 35-55 years; G3: 55-75 years; G4: >75 years)...
June 26, 2024: Heart
https://read.qxmd.com/read/38925881/intracoronary-thrombolysis-in-st-elevation-myocardial-infarction-a-systematic-review-and-meta-analysis
#7
JOURNAL ARTICLE
Rajan Rehan, Sohaib Virk, Christopher C Y Wong, Freda Passam, Jamie Layland, Anthony Keech, Andy Yong, Harvey D White, William Fearon, Martin Ng
BACKGROUND: Despite restoration of epicardial blood flow in acute ST-elevation myocardial infarction (STEMI), inadequate microcirculatory perfusion is common and portends a poor prognosis. Intracoronary (IC) thrombolytic therapy can reduce microvascular thrombotic burden; however, contemporary studies have produced conflicting outcomes. OBJECTIVES: This meta-analysis aims to evaluate the efficacy and safety of adjunctive IC thrombolytic therapy at the time of primary percutaneous coronary intervention (PCI) among patients with STEMI...
June 26, 2024: Heart
https://read.qxmd.com/read/38906683/enzyme-replacement-therapy-in-fabry-cardiomyopathy-an-incomplete-treatment
#8
EDITORIAL
Kathleen Nicholls
No abstract text is available yet for this article.
June 21, 2024: Heart
https://read.qxmd.com/read/38849151/long-term-prognosis-of-low-high-sensitivity-cardiac-troponin-t-in-the-emergency-department-compared-with-the-general-population
#9
JOURNAL ARTICLE
Love Cyon, Erik Kadesjö, Gustaf Edgren, Andreas Roos
BACKGROUND: Long-term prognosis associated with low-high-sensitivity cardiac troponin T (hs-cTnT) concentrations in patients with chest pain is unknown. We investigated these prognostic implications compared with the general population. METHODS: All first visits to seven emergency departments (ED)s in Sweden were included from 9 December 2010 to 31 August, 2017 by patients presenting with chest pain and at least one hs-cTnT measured. Patients with myocardial injury (any hs-cTnT >14 ng/L), including patients with myocardial infarction (MI) were excluded...
June 7, 2024: Heart
https://read.qxmd.com/read/38816063/evidence-of-cardiomyopathy-associated-with-marfan-syndrome-in-children
#10
JOURNAL ARTICLE
Justin Weigand, Sara Stephens-Novy, Shagun Sachdeva, Tam T Doan, Abigail Yasso, Shaine A Morris
OBJECTIVE: Marfan syndrome (MFS)-associated cardiomyopathy, defined as ventricular dilation and dysfunction unexplained by volume loading, is not well defined in children. This study evaluated ventricular size and function in paediatric MFS using cardiac MRI (cMRI). METHODS: This retrospective cohort study examined patients with MFS <19 years old at first cMRI. Left ventricular (LV) ejection fraction (EF) <55% was considered abnormal, as were z-scores >2...
May 30, 2024: Heart
https://read.qxmd.com/read/38802128/integrating-machine-learning-approach-to-identify-sleep-disordered-breathing-in-hypertrophic-cardiomyopathy
#11
EDITORIAL
Tae-Min Rhee, Hyung-Kwan Kim
No abstract text is available yet for this article.
May 27, 2024: Heart
https://read.qxmd.com/read/38802127/bridging-the-gap-understanding-sex-differences-in-low-density-lipoprotein-cholesterol-control-through-the-lens-of-integrated-data-analysis-and-behavioural-sciences
#12
EDITORIAL
https://read.qxmd.com/read/38768982/automatic-detection-of-cardiac-conditions-from-photos-of-electrocardiogram-captured-by-smartphones
#13
JOURNAL ARTICLE
Chun-Ka Wong, Yuk Ming Lau, Hin Wai Lui, Wai Fung Chan, Wing Chun San, Mi Zhou, Yangyang Cheng, Duo Huang, Wing Hon Lai, Yee Man Lau, Chung Wah Siu
BACKGROUND: Researchers have developed machine learning-based ECG diagnostic algorithms that match or even surpass cardiologist level of performance. However, most of them cannot be used in real-world, as older generation ECG machines do not permit installation of new algorithms. OBJECTIVE: To develop a smartphone application that automatically extract ECG waveforms from photos and to convert them to voltage-time series for downstream analysis by a variety of diagnostic algorithms built by researchers...
May 20, 2024: Heart
https://read.qxmd.com/read/38754969/modelled-impact-of-virtual-fractional-flow-reserve-in-patients-undergoing-coronary-angiography-virtu-4
#14
JOURNAL ARTICLE
Mina Ghobrial, Hazel Haley, Rebecca Gosling, Daniel James Taylor, James Richardson, Kenneth Morgan, David Barmby, Javaid Iqbal, Arvindra Krishnamurthy, Rajender Singh, Dwayne Conway, Ian Hall, Zulfiquar Adam, Nigel Wheeldon, Ever D Grech, Robert F Storey, Alexander Rothman, Gillian Payne, Muhammad Naeem Tahir, Simon Smith, Justin Cooke, Steven Hunter, Neil Cartwright, Syed Sadeque, Norman Paul Briffa, Abdallah Al-Mohammad, Laurence O'Toole, Dominic Rogers, Patricia V Lawford, David R Hose, Julian Gunn, Paul D Morris
BACKGROUND: The practical application of 'virtual' (computed) fractional flow reserve (vFFR) based on invasive coronary angiogram (ICA) images is unknown. The objective of this cohort study was to investigate the potential of vFFR to guide the management of unselected patients undergoing ICA. The hypothesis was that it changes management in >10% of cases. METHODS: vFFR was computed using the Sheffield VIRTUheart system, at five hospitals in the North of England, on 'all-comers' undergoing ICA for non-ST-elevation myocardial infarction acute coronary syndrome (ACS) and chronic coronary syndrome (CCS)...
May 16, 2024: Heart
https://read.qxmd.com/read/38772575/heart-s-hidden-battle-understanding-erdheim-chester-disease
#15
EDITORIAL
Ryosuke Sato, Frauke Czepluch, Stephan von Haehling
No abstract text is available yet for this article.
May 15, 2024: Heart
https://read.qxmd.com/read/38772573/future-applications-of-incidental-detection-of-thoracic-and-coronary-calcium-for-atherosclerotic-cardiovascular-disease-events-prediction
#16
EDITORIAL
Craig Balmforth, Marc R Dweck
No abstract text is available yet for this article.
May 15, 2024: Heart
https://read.qxmd.com/read/38749654/fabry-disease-development-and-progression-of-left-ventricular-hypertrophy-despite-long-term-enzyme-replacement-therapy
#17
JOURNAL ARTICLE
Niccolo Maurizi, Albina Nowak, Christiane Gruner, Mehdi Namdar, Christian Schmied, Alessandra Pia Porretta, Guillaume Barbey, Veronique Monzambani, Pierre Monney, Frédéric Barbey
BACKGROUND: Enzyme replacement therapy (ERT) may halt or attenuate disease progression in patients with Anderson-Fabry disease (AFD). However, whether left ventricular hypertrophy (LVH) can be prevented by early therapy or may still progress despite ERT over a long-term follow-up is still unclear. METHODS: Consecutive patients with AFD from the Independent Swiss-Fabry Cohort receiving ERT who were at least followed up for 5 years were included. Cardiac progression was defined as an increase of >10 g/m2 in left ventricular mass index (LVMI) between the first and the last available follow-up transthoracic echocardiography...
May 15, 2024: Heart
https://read.qxmd.com/read/38729636/urinary-proteomic-signature-of-mineralocorticoid-receptor-antagonism-by-spironolactone-evidence-from-the-homage-trial
#18
JOURNAL ARTICLE
Yu-Ling Yu, Justyna Siwy, De-Wei An, Arantxa González, Tine Hansen, Agnieszka Latosinska, Pierpaolo Pellicori, Susana Ravassa, Beatrice Mariottoni, Job Aj Verdonschot, Fozia Ahmed, Johannes Petutschnigg, Patrick Rossignol, Stephane Heymans, Joe J Cuthbert, Nicolas Girerd, Andrew L Clark, Peter Verhamme, Tim S Nawrot, Stefan Janssens, John G Cleland, Faiez Zannad, Javier Diez, Harald Mischak, João Pedro Ferreira, Jan A Staessen
OBJECTIVE: Heart failure (HF) is characterised by collagen deposition. Urinary proteomic profiling (UPP) followed by peptide sequencing identifies parental proteins, for over 70% derived from collagens. This study aimed to refine understanding of the antifibrotic action of spironolactone. METHODS: In this substudy (n=290) to the Heart 'Omics' in Ageing Study trial, patients were randomised to usual therapy combined or not with spironolactone 25-50 mg/day and followed for 9 months...
May 9, 2024: Heart
https://read.qxmd.com/read/38627022/thoracic-versus-coronary-calcification-for-atherosclerotic-cardiovascular-disease-events-prediction
#19
JOURNAL ARTICLE
Keishi Ichikawa, Rui Wang, Robyn L McClelland, Venkat S Manubolu, Shriraj Susarla, Duo Lee, Leili Pourafkari, Hooman Fazlalizadeh, Jairo Aldana Bitar, Rick Robin, April Kinninger, Sion Roy, Wendy S Post, Matthew Budoff
UNLABELLED: This study compared the prognostic value of quantified thoracic artery calcium (TAC) including aortic arch on chest CT and coronary artery calcium (CAC) score on ECG-gated cardiac CT. METHODS: A total of 2412 participants who underwent both chest CT and ECG-gated cardiac CT at the same period were included in the Multi-Ethnic Study of Atherosclerosis Exam 5. All participants were monitored for incident atherosclerotic cardiovascular disease (ASCVD) events...
April 23, 2024: Heart
https://read.qxmd.com/read/38649264/sarcopenia-and-aortic-valve-disease
#20
REVIEW
Manish Kumar, Anthony Pettinato, Feria Ladha, Jacob E Earp, Varun Jain, Shivaraj Patil, Daniel T Engelman, Peter F Robinson, Mohamad B Moumneh, Parag Goyal, Abdulla A Damluji
Valvular heart disease, including calcific or degenerative aortic stenosis (AS), is increasingly prevalent among the older adult population. Over the last few decades, treatment of severe AS has been revolutionised following the development of transcatheter aortic valve replacement (TAVR). Despite improvements in outcomes, older adults with competing comorbidities and geriatric syndromes have suboptimal quality of life outcomes, highlighting the cumulative vulnerability that persists despite valve replacement...
April 22, 2024: Heart
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