journal
https://read.qxmd.com/read/36931716/haemodynamic-and-metabolic-adaptations-in-coronary-microvascular-disease
#1
JOURNAL ARTICLE
Samer Noaman, David M Kaye, Shane Nanayakkara, Anthony M Dart, Andy S C Yong, Martin Ng, Donna Vizi, Stephen J Duffy, Nicholas Cox, William Chan
OBJECTIVE: We aimed to evaluate the microcirculatory resistance (MR) and myocardial metabolic adaptations at rest and in response to increased cardiac workload in patients with suspected coronary microvascular dysfunction (CMD). METHODS: Patients with objective ischaemia and/or myocardial injury and non-obstructive coronary artery disease underwent thermodilution-derived microcirculatory assessment and transcardiac blood sampling during graded exercise with adenosine-mediated hyperaemia...
March 17, 2023: Heart
https://read.qxmd.com/read/36928243/elective-ascending-aortic-aneurysm-repair-outcomes-in-a-nationwide-us-cohort
#2
JOURNAL ARTICLE
Sebastian E Beyer, Eric A Secemsky, Kamal Khabbaz, Brett J Carroll
OBJECTIVE: To quantify contemporary outcomes following elective ascending aortic aneurysm repair, to determine risk factors for adverse events and to evaluate difference by institutional surgical volume. METHODS: We included all elective hospitalisations of adult patients with an ascending aortic aneurysm who underwent aneurysm repair in the Nationwide Readmissions Database between 2016 and 2019. The primary outcome was a composite of in-hospital mortality, stroke (ischaemic and non-ischaemic) and myocardial infarction (MI)...
March 16, 2023: Heart
https://read.qxmd.com/read/36928242/role-of-percutaneous-coronary-intervention-in-the-modern-day-management-of-chronic-coronary-syndrome
#3
REVIEW
Timothy Cartlidge, Mila Kovacevic, Eliano Pio Navarese, Gerald Werner, Vijay Kunadian
Contemporary randomised trials of percutaneous coronary intervention (PCI) in chronic coronary syndrome (CCS) demonstrate no difference between patients treated with a conservative or invasive strategy with respect to all-cause mortality or myocardial infarction, although trials lack power to test for individual endpoints and long-term follow-up data are needed. Open-label trials consistently show greater improvement in symptoms and quality of life among patients with stable angina treated with PCI. Further studies are awaited to clarify this finding...
March 16, 2023: Heart
https://read.qxmd.com/read/36928241/one-year-quality-of-life-outcomes-of-cardiac-arrest-survivors-by-initial-defibrillation-provider
#4
JOURNAL ARTICLE
Brian Haskins, Ziad Nehme, Emily Andrew, Stephen Bernard, Peter Cameron, Karen Smith
OBJECTIVE: To assess the long-term functional and health-related quality-of-life (HRQoL) outcomes for out-of-hospital cardiac arrest (OHCA) survivors stratified by initial defibrillation provider. METHODS: This retrospective study included adult non-traumatic OHCA with initial shockable rhythms between 2010 and 2019. Survivors at 12 months after arrest were invited to participate in structured telephone interviews. Outcomes were identified using the Glasgow Outcome Scale-Extended (GOS-E), EuroQol-5 Dimension (EQ-5D), 12-Item Short Form Health Survey and living and work status-related questions...
March 16, 2023: Heart
https://read.qxmd.com/read/36918267/left-atrial-phasic-function-physiology-clinical-assessment-and-prognostic-value
#5
REVIEW
Aaisha Ferkh, Amy Clark, Liza Thomas
Left atrial (LA) phasic function provides significant insights into the pathophysiology of cardiovascular disease. LA function is described in three phases: reservoir (atrial filling, during systole), conduit (passive emptying, during early diastole) and contractile (active emptying, during late diastole). LA phasic function can be evaluated by different imaging modalities, and a variety of techniques including volumetric analysis, deformation (strain) and Doppler methods. LA phasic function (particularly LA reservoir strain) is more sensitive and provides earlier detection of LA dysfunction than alterations in LA volume...
March 14, 2023: Heart
https://read.qxmd.com/read/36918266/primary-prevention-of-cardiovascular-disease-in-women-with-a-mediterranean-diet-systematic-review-and-meta-analysis
#6
JOURNAL ARTICLE
Anushriya Pant, Sarah Gribbin, Daniel McIntyre, Ritu Trivedi, Simone Marschner, Liliana Laranjo, Mamas A Mamas, Victoria Flood, Clara K Chow, Sarah Zaman
BACKGROUND: Dietary modification is a cornerstone of cardiovascular disease (CVD) prevention. A Mediterranean diet has been associated with a lower risk of CVD but no systematic reviews have evaluated this relationship specifically in women. OBJECTIVE: To determine the association between higher versus lower adherence to a Mediterranean diet and incident CVD and total mortality in women. METHODS: A systematic search of Medline, Embase, CINAHL, Scopus, and Web of Science (2003-21) was performed...
March 14, 2023: Heart
https://read.qxmd.com/read/36914251/severe-aortic-stenosis-and-the-need-for-the-right-treatment-in-the-right-place-at-the-right-time
#7
EDITORIAL
Zulfiqar Ali, Aidan W Flynn
No abstract text is available yet for this article.
March 13, 2023: Heart
https://read.qxmd.com/read/36914250/sex-specific-trajectories-of-molecular-cardiometabolic-traits-from-childhood-to-young-adulthood
#8
JOURNAL ARTICLE
Linda M O'Keeffe, Kate Tilling, Joshua A Bell, Patrick T Walsh, Matthew A Lee, Deborah A Lawlor, George Davey Smith, Patricia M Kearney
BACKGROUND: The changes which typically occur in molecular causal risk factors and predictive biomarkers for cardiometabolic diseases across early life are not well characterised. METHODS: We quantified sex-specific trajectories of 148 metabolic trait concentrations including various lipoprotein subclasses from age 7 years to 25 years. Data were from 7065 to 7626 offspring (11 702 to14 797 repeated measures) of the Avon Longitudinal Study of Parents and Children birth cohort study...
March 13, 2023: Heart
https://read.qxmd.com/read/36914249/exercise-and-arrhythmogenic-cardiomyopathy-all-things-in-moderation
#9
EDITORIAL
Graham Bevan, Babak Nazer
No abstract text is available yet for this article.
March 13, 2023: Heart
https://read.qxmd.com/read/36914248/trajectories-of-lipoproteins-and-molecular-cardiometabolic-traits-by-sex-from-childhood-to-adulthood
#10
EDITORIAL
Carolina G Downie, Xinruo Zhang
No abstract text is available yet for this article.
March 13, 2023: Heart
https://read.qxmd.com/read/36914247/role-of-computed-tomography-cardiac-angiography-in-acute-chest-pain-syndromes
#11
REVIEW
Charlotte Greer, Michelle C Williams, David E Newby, Philip D Adamson
Use of CT coronary angiography (CTCA) to evaluate chest pain has rapidly increased over the recent years. While its utility in the diagnosis of coronary artery disease in stable chest pain syndromes is clear and is strongly endorsed by international guidelines, the role of CTCA in the acute setting is less certain. In the low-risk setting, CTCA has been shown to be accurate, safe and efficient but inherent low rates of adverse events in this population and the advent of high-sensitivity troponin testing have left little room for CTCA to show any short-term clinical benefit...
March 13, 2023: Heart
https://read.qxmd.com/read/36898707/holistic-approach-to-drug-therapy-in-a-patient-with-heart-failure
#12
JOURNAL ARTICLE
Paul Forsyth, Janine Beezer, Joanne Bateman
Heart failure (HF) is a growing global public health problem affecting at least 26 million people worldwide. The evidence-based landscape for HF treatment has changed at a rapid rate over the last 30 years. International guidelines for the management of HF now recommend the use of four pillars in all patients with reduced ejection fraction: angiotensin receptor neprilysin inhibitors or ACE inhibitors, beta blockers, mineralocorticoid receptor antagonists and sodium-glucose co-transporter-2 inhibitors...
March 10, 2023: Heart
https://read.qxmd.com/read/36898706/expert-consensus-recommendations-for-the-provision-of-infective-endocarditis-services-updated-guidance-from-the-joint-british-societies
#13
JOURNAL ARTICLE
Jonathan A T Sandoe, Fozia Ahmed, Parthiban Arumugam, Achyut Guleri, Carolyne Horner, Philip Howard, John Perry, Bernard D Prendergast, Ralph Schwiebert, Richard Paul Steeds, Richard Watkin, Olaf Wendler, John B Chambers
Infective endocarditis (IE) remains a difficult condition to diagnose and treat and is an infection of high consequence for patients, causing long hospital stays, life-changing complications and high mortality. A new multidisciplinary, multiprofessional, British Society for Antimicrobial Chemotherapy (BSAC)-ledWorking Party was convened to undertake a focused systematical review of the literature and to update the previous BSAC guidelines relating delivery of services for patients with IE. A scoping exercise identified new questions concerning optimal delivery of care, and the systematic review identified 16 231 papers of which 20 met the inclusion criteria...
March 10, 2023: Heart
https://read.qxmd.com/read/36898705/expanding-perspective-considering-opioids-in-the-management-of-dyspnoea-in-end-stage-heart-failure
#14
EDITORIAL
Kathryn A Schlenker, Jill M Steiner
No abstract text is available yet for this article.
March 10, 2023: Heart
https://read.qxmd.com/read/36898704/prognostic-models-for-heart-failure-in-patients-with-type-2-diabetes-a-systematic-review-and-meta-analysis
#15
JOURNAL ARTICLE
Georgios Kostopoulos, Ioannis Doundoulakis, Konstantinos A Toulis, Thomas Karagiannis, Apostolos Tsapas, Anna-Bettina Haidich
OBJECTIVE: To provide a systematic review, critical appraisal, assessment of performance and generalisability of all the reported prognostic models for heart failure (HF) in patients with type 2 diabetes (T2D). METHODS: We performed a literature search in Medline, Embase, Central Register of Controlled Trials, Cochrane Database of Systematic Reviews and Scopus (from inception to July 2022) and grey literature to identify any study developing and/or validating models predicting HF applicable to patients with T2D...
March 10, 2023: Heart
https://read.qxmd.com/read/36898703/time-to-scale-up-access-to-cost-effective-home-based-digitally-supported-models-of-rehabilitation-delivery
#16
EDITORIAL
Rod Taylor, Heather Lynne Fraser
No abstract text is available yet for this article.
March 10, 2023: Heart
https://read.qxmd.com/read/36889907/evolution-and-triggers-of-defibrillator-shocks-in-patients-with-arrhythmogenic-right-ventricular-cardiomyopathy
#17
JOURNAL ARTICLE
Nadine Molitor, Daniel Hofer, Tolga Çimen, Alessio Gasperetti, Deniz Akdis, Sarah Costa, Rolf Jenni, Alexander Breitenstein, Thomas Wolber, Stephan Winnik, Siv Fokstuen, Guan Fu, Argelia Medeiros-Domingo, Frank Ruschitzka, Corinna Brunckhorst, Firat Duru, Ardan M Saguner
INTRODUCTION: Implantable cardioverter-defibrillators (ICDs) can prevent sudden cardiac death due to ventricular arrhythmias in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC). The aim of our study was to assess the cumulative burden, evolution and potential triggers of appropriate ICD shocks during long-term follow-up, which may help to reduce and further refine individual arrhythmic risk in this challenging disease. METHODS: This retrospective cohort study included 53 patients with definite ARVC according to the 2010 Task Force Criteria from the multicentre Swiss ARVC Registry with an implanted ICD for primary or secondary prevention...
March 8, 2023: Heart
https://read.qxmd.com/read/36882327/interventional-management-of-out-of-hospital-cardiac-arrest
#18
JOURNAL ARTICLE
Nicole Karam, Christian Spaulding
No abstract text is available yet for this article.
March 7, 2023: Heart
https://read.qxmd.com/read/36878673/comparative-effect-of-varenicline-and-nicotine-patches-on-preventing-repeat-cardiovascular-events
#19
JOURNAL ARTICLE
Annelies L Robijn, Kristian B Filion, Mark Woodward, Benjumin Hsu, Clara K Chow, Sallie-Anne Pearson, Louisa Jorm, Michael O Falster, Alys Havard
OBJECTIVE: To determine the comparative effectiveness of postdischarge use of varenicline versus prescription nicotine replacement therapy (NRT) patches for the prevention of recurrent cardiovascular events and mortality and whether this association differs by sex. METHODS: Our cohort study used routinely collected hospital, pharmaceutical dispensing and mortality data for residents of New South Wales, Australia. We included patients hospitalised for a major cardiovascular event or procedure 2011-2017, who were dispensed varenicline or prescription NRT patches within 90day postdischarge...
March 6, 2023: Heart
https://read.qxmd.com/read/36878672/likelihood-reclassification-by-an-acoustic-based-score-in-suspected-coronary-artery-disease
#20
JOURNAL ARTICLE
Laust Dupont Rasmussen, Simon Winther, Salma Raghad Karim, Jelmer Westra, Jane Kirk Johansen, Hanne Maare Søndergaard, Osama Hammid, Emelyne Sevestre, Yoshinobu Onuma, Mette Nyegaard, June Anita Ejlersen, Evald Christiansen, Ashkan Eftekhari, Niels Ramsing Holm, Samuel Emil Schmidt, Morten Bøttcher
OBJECTIVE: Validation studies of the 2019 European Society of Cardiology pretest probability model (ESC-PTP) for coronary artery disease (CAD) report that 35%-40% of patients have low pretest probability (ESC-PTP 5% to <15%). Acoustic detection of coronary stenoses could potentially improve clinical likelihood stratification. Aims were to (1) investigate the diagnostic performance of an acoustic-based CAD score and (2) study the reclassification potential of a dual likelihood strategy by the ESC-PTP and a CAD score...
March 6, 2023: Heart
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