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Heart: Official Journal of the British Cardiac Society

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https://read.qxmd.com/read/30898850/atrial-fibrillation-what-do-we-know-about-screening-and-what-do-we-not-know-about-treatment
#1
EDITORIAL
Sean D Pokorney, Renato D Lopes
No abstract text is available yet for this article.
March 21, 2019: Heart: Official Journal of the British Cardiac Society
https://read.qxmd.com/read/30898849/external-continuous-ecg-versus-loop-recording-for-atrial-fibrillation-detection-in-patients-who-had-a-stroke
#2
Michala Herskind Sejr, Ole May, Dorte Damgaard, Birgitte Forsom Sandal, Jens Cosedis Nielsen
BACKGROUND: Detection of atrial fibrillation (AF) in patients who had ischaemic stroke and transient ischaemic attack (IS/TIA) is recommended. We aimed to compare external loop recording (ELR) against simultaneous continuous ECG recording for AF detection in patients who had acute IS/TIA and determine sensitivity, specificity and positive predictive value of AF detection using ELR. We hypothesised ELR to detect 15% fewer patients with AF than continuous ECG recording. METHODS: In this prospective cohort study, we included 1412 patients who had acute IS/TIA without prior AF...
March 21, 2019: Heart: Official Journal of the British Cardiac Society
https://read.qxmd.com/read/30877239/implications-of-the-local-haemodynamic-forces-on-the-phenotype-of-coronary-plaques
#3
Christos V Bourantas, Thomas Zanchin, Antonis Sakellarios, Alexios Karagiannis, Anantharaman Ramasamy, Kyohei Yamaji, Masanori Taniwaki, Dik Heg, Aris Moschovitis, Dimitrios Fotiadis, Lampros Mihalis, Andreas Baumbach, Ryo Torii, Patrick Serruys, Hector M Garcia-Garcia, Stephan Windecker, Lorenz Räber
AIM: To examine the effect of endothelial shear stress (ESS) on the dynamic changes in plaque phenotype. METHODS: Patients with myocardial infarction that had intravascular ultrasound-virtual histology (IVUS-VH) and optical coherence tomography (OCT) at baseline and 13-month follow-up were studied. The IVUS-VH data were used to reconstruct the nonculprit vessels, and in the obtained models the ESS was estimated in 3 mm segments. Plaque morphology was derived in each segment from IVUS-VH and OCT...
March 15, 2019: Heart: Official Journal of the British Cardiac Society
https://read.qxmd.com/read/30872386/cardiovascular-risk-in-159-934-frequent-blood-donors-while-addressing-the-healthy-donor-effect
#4
Karlijn Peffer, Martin den Heijer, Wim L A M de Kort, André L M Verbeek, Femke Atsma
OBJECTIVE: To investigate whether regular blood donation decreases cardiovascular risk. METHODS: All 159 934 Dutch whole-blood donors with an active donation career of at least 10 years were categorised into sex-specific donation tertiles based on the number of donations during this 10-year qualification period. Cardiovascular endpoints were based on hospital discharge diagnoses and death certificates from Dutch Hospital Data and Statistics Netherlands and occurring after the 10-year qualification period...
March 14, 2019: Heart: Official Journal of the British Cardiac Society
https://read.qxmd.com/read/30867148/antithrombotic-therapy-in-patients-undergoing-transcatheter-aortic-valve-implantation
#5
REVIEW
Vincent Johan Nijenhuis, Jorn Brouwer, Lars Søndergaard, Jean-Philippe Collet, Erik Lerkevang Grove, Jurrien Maria Ten Berg
This review provides a comprehensive overview of the available data on antithrombotic therapy after transcatheter aortic valve implantation (TAVI). In the absence of large randomised clinical trials, clinical practice is leaning towards evidence reported in other populations. Due to the greater risk of major bleeding associated with oral anticoagulation using a vitamin-K antagonist (VKA), antiplatelet therapy (APT) may be considered as the first-line treatment of patients undergoing TAVI. Overall, single rather than dual APT is preferred...
March 13, 2019: Heart: Official Journal of the British Cardiac Society
https://read.qxmd.com/read/30862643/sst2-a-new-kid-on-the-block-for-patients-with-achd
#6
EDITORIAL
Oktay Tutarel
No abstract text is available yet for this article.
March 12, 2019: Heart: Official Journal of the British Cardiac Society
https://read.qxmd.com/read/30862642/aortic-valve-area-too-important-for-splendid-isolation
#7
EDITORIAL
Jan Minners
No abstract text is available yet for this article.
March 12, 2019: Heart: Official Journal of the British Cardiac Society
https://read.qxmd.com/read/30842207/proprotein-convertase-subtilisin-kexin-9-inhibitors-in-reducing-cardiovascular-outcomes-a-systematic-review-and-meta-analysis
#8
Heyue Du, Xiaodan Li, Na Su, Ling Li, Xiaoting Hao, Haihui Gao, Joey Sum-Wing Kwong, Per Olav Vandvik, Xueli Yang, Imola Nemeth, Mordi R Ify, Qianrui Li, Longhao Zhang, Li Rao, Chim C Lang, Jianshu Li, Haoming Tian, Sheyu Li
BACKGROUND: To evaluate the effects of proprotein convertase subtilisin/kexin 9 (PCSK9) inhibitors on major adverse cardiovascular events (MACE). METHODS: Our systematic review included randomised controlled trials if they studied PCSK9 inhibitors in patients for primary and/or secondary prevention of cardiovascular diseases or with hypercholesterolaemia/hyperlipidaemia. Dichotomous variables from individual studies were pooled by relative risks (RR) and their 95% CIs using the random-effect model...
March 6, 2019: Heart: Official Journal of the British Cardiac Society
https://read.qxmd.com/read/30826773/calculated-plasma-volume-status-and-outcomes-in-patients-undergoing-coronary-bypass-graft-surgery
#9
Annette Marie Maznyczka, Mohamad Fahed Barakat, Bassey Ussen, Amit Kaura, Huda Abu-Own, Fadi Jouhra, Hannah Jaumdally, George Amin-Youssef, Niki Nicou, Max Baghai, Ranjit Deshpande, Olaf Wendler, Shyam Kolvekar, Darlington O Okonko
OBJECTIVES: Congestion is associated with worse outcomes in critically ill surgical patients but can be difficult to quantify noninvasively. We hypothesised that plasma volume status (PVS), estimated preoperatively using a validated formula that enumerates percentage change from ideal plasma volume (PV), would provide incremental prognostic utility after coronary artery bypass graft (CABG) surgery. METHODS: In this retrospective cohort study, patients who underwent CABG surgery (1999-2010) were identified from a prospectively collected database...
March 2, 2019: Heart: Official Journal of the British Cardiac Society
https://read.qxmd.com/read/30826772/global-lessons-from-deaths-from-heart-failure-in-uk-hospitals
#10
EDITORIAL
Lisa J Anderson, Iain B Squire, Martin R Cowie
No abstract text is available yet for this article.
March 2, 2019: Heart: Official Journal of the British Cardiac Society
https://read.qxmd.com/read/30826771/non-invasive-measurements-of-arterial-function-what-when-why-should-we-use-them
#11
Zoe Dong Yang Sun, Joseph Cheriyan
No abstract text is available yet for this article.
March 2, 2019: Heart: Official Journal of the British Cardiac Society
https://read.qxmd.com/read/30826770/fenestration-in-the-fontan-circulation-as-a-strategy-for-chronic-cardioprotection
#12
Hirofumi Saiki, Seiko Kuwata, Yoichi Iwamoto, Hirotaka Ishido, Mio Taketazu, Satoshi Masutani, Takashi Nishida, Hideaki Senzaki
BACKGROUND: Fenestration in the Fontan circulation potentially liberates patients from factors leading to cardiovascular remodelling, through stable haemodynamics with attenuated venous congestion. We hypothesised that a fenestrated Fontan procedure would possess chronic haemodynamic advantages beyond the preload preservation. METHODS: We enrolled 35 patients with fenestrated Fontan with a constructed pressure-volume relationship under dobutamine (DOB) infusion and/or transient fenestration occlusion (TFO)...
March 2, 2019: Heart: Official Journal of the British Cardiac Society
https://read.qxmd.com/read/30824479/acute-mitral-regurgitation
#13
REVIEW
Nozomi Watanabe
The diagnosis of acute mitral regurgitation (MR) is often missed or delayed because the clinical presentation is substantially different from that in patients with chronic MR. Management of acute MR depends on the specific aetiology of valve dysfunction and there is a lack of consensus on the optimal therapeutic approach in many patients. In particular, management of secondary MR due to acute ischaemia is challenging because of unique mechanisms of valve incompetence compared with chronic ischaemic MR. Another clinical challenge is management of acute MR due to transient systolic anterior motion of the mitral valve in the acute phase of Takotsubo cardiomyopathy, which commonly resolves within a few weeks...
March 1, 2019: Heart: Official Journal of the British Cardiac Society
https://read.qxmd.com/read/30824478/interpretation-of-a-coronary-angiogram
#14
Leah Raj, David Shavelle, Anilkumar Mehra
CLINICAL INTRODUCTION: A 42 year-old man with hypertension, hyperlipidaemia and tobacco abuse presented with typical chest pain. The pain was located in the substernal area, described as squeezing, non-radiating and awoke him from sleep. The pain was not associated with shortness of breath, abdominal pain, nausea and diaphoresis. On physical examination, blood pressure was 171/115 mm Hg, heart rate was 60 beats/min, heart sounds were normal without murmur, lung fields were clear and there was no peripheral oedema...
March 1, 2019: Heart: Official Journal of the British Cardiac Society
https://read.qxmd.com/read/30819763/cardiovascular-risk-factors-and-disease-among-non-european-immigrants-living-in-catalonia
#15
Miguel Cainzos-Achirica, Emili Vela, Montse Cleries, Usama Bilal, Josepa Mauri, Maria Jesus Pueyo, Alba Rosas, Cristina Enjuanes, Michael J Blaha, Alka M Kanaya, Josep Comin-Colet
OBJECTIVE: To describe the prevalence and incidence of cardiovascular risk factors, established cardiovascular disease (CVD) and cardiovascular medication use, among immigrant individuals of diverse national origins living in Catalonia (Spain), a region receiving large groups of immigrants from all around the world, and with universal access to healthcare. METHODS: We conducted a population-based analysis including >6 million adult individuals living in Catalonia, using the local administrative healthcare databases...
February 28, 2019: Heart: Official Journal of the British Cardiac Society
https://read.qxmd.com/read/30792241/living-alone-and-cardiovascular-disease-outcomes
#16
Sumeet Gandhi, Shaun G Goodman, Nicola Greenlaw, Ian Ford, Paula McSkimming, Roberto Ferrari, Yangsoo Jang, Marco Antonio Alcocer-Gamba, Kim Fox, Jean-Claude Tardif, Michal Tendera, Paul Dorian, Gabriel Steg, Jacob Allan Udell
OBJECTIVE: To evaluate cardiovascular (CV) outcomes in outpatients with coronary artery disease (CAD) living alone compared with those living with others. METHODS: The prospeCtive observational LongitudinAl RegIstry oF patients with stable coronarY artery disease (CLARIFY) included outpatients with stable CAD. CLARIFY enrolled participants in 45 countries from November 2009 to July 2010, with 5 years of follow-up. Living arrangement was documented at baseline. The primary outcome was a composite of major adverse cardiovascular events (MACEs) defined as CV death, myocardial infarction (MI) and stroke...
February 21, 2019: Heart: Official Journal of the British Cardiac Society
https://read.qxmd.com/read/30792240/pregnancy-in-women-with-pre-existent-ischaemic-heart-disease-a-systematic-review-with-individualised-patient-data
#17
REVIEW
Heleen Lameijer, Luke J Burchill, Lucia Baris, Titia Pe Ruys, Jolien W Roos-Hesselink, Barbara J M Mulder, Candice K Silversides, Dirk J van Veldhuisen, Petronella G Pieper
INTRODUCTION: Studies on pregnancy risk in women with ischaemic heart disease (IHD) have mainly excluded pregnancies in women with pre-existent IHD. There is a need for better information about the pregnancy risks in these women and their offspring. METHODS: We performed a systematic review searching the PubMed/MEDLINE public database for pregnancy in women with pre-existent IHD analysing the cardiac, obstetric and fetal/neonatal outcome of pregnancy in women with pre-existing IHD...
February 21, 2019: Heart: Official Journal of the British Cardiac Society
https://read.qxmd.com/read/30792239/arrhythmogenic-cardiomyopathies-acs-diagnosis-risk-stratification-and-management
#18
Alexandros Protonotarios, Perry M Elliott
No abstract text is available yet for this article.
February 21, 2019: Heart: Official Journal of the British Cardiac Society
https://read.qxmd.com/read/30792238/epidemiology-and-long-term-outcome-in-outpatients-with-chronic-heart-failure-in-northwestern-europe
#19
Hanna Fröhlich, Niklas Rosenfeld, Tobias Täger, Kevin Goode, Syed Kazmi, Torstein Hole, Hugo A Katus, Dan Atar, John G F Cleland, Stefan Agewall, Andrew L Clark, Lutz Frankenstein, Morten Grundtvig
OBJECTIVE: To describe the epidemiology, long-term outcomes and temporal trends in mortality in ambulatory patients with chronic heart failure (HF) with reduced (HFrEF), mid-range (HFmrEF) or preserved ejection fraction (HFpEF) from three European countries. METHODS: We identified 10 312 patients from the Norwegian HF Registry and the HF registries of the universities of Heidelberg, Germany, and Hull, UK. Patients were classified according to baseline left ventricular ejection fraction (LVEF) and time of enrolment (period 1: 1995-2005 vs period 2: 2006-2015)...
February 21, 2019: Heart: Official Journal of the British Cardiac Society
https://read.qxmd.com/read/30792237/risk-of-cardiac-and-sudden-death-with-and-without-revascularisation-of-a-coronary-chronic-total-occlusion
#20
Cosmo Godino, Alessia Giannattasio, Andrea Scotti, Luca Baldetti, Carlo Andrea Pivato, Andrea Munafò, Alberto Cappelletti, Alessandro Beneduce, Francesco Melillo, Mauro Chiarito, Giuseppe Biondi Zoccai, Giacomo Frati, Gabriele Fragasso, Lorenzo Azzalini, Mauro Carlino, Matteo Montorfano, Alberto Margonato, Antonio Colombo
OBJECTIVE: The aim of this study is to evaluate the long-term risk of cardiac death and sudden cardiac death (SCD) and/or sustained ventricular arrhythmias (SVAs) in patients with coronary chronic total occlusions (CTO) revascularised versus those with CTO not revascularised by percutaneous coronary intervention (PCI). METHODS: From a cohort of 1357 CTO-PCI patients, 1162 patients who underwent CTO PCI attempt were included in this long-term analysis: 837 patients were revascularised by PCI (CTO-R group) and 325 were not revascularised (CTO-NR group)...
February 21, 2019: Heart: Official Journal of the British Cardiac Society
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