Gastrointestinal Endoscopy

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.

BACKGROUND AND AIMS: Prophylactic application of a hemoclip has been suggested as an alternative to the use of an endoloop for the prevention of postpolypectomy bleeding (PPB) when resecting large, pedunculated colorectal polyps. Therefore, this multicenter, randomized controlled trial investigated the efficacy of prophylactic hemoclip application to reduce PPB during the resection of large pedunculated polyps. METHODS: Large pedunculated polyps (≥10 mm in head diameter) were eligible for inclusion...

BACKGROUND AND AIMS: Studies evaluating the role of routine second-look endoscopy in patients with acute upper gastrointestinal bleeding (UGIB) due to peptic ulcer disease (PUD) have reported conflicting results. This meta-analysis evaluates the usefulness of routine second-look endoscopy in these patients. METHODS: We reviewed several databases from inception to September 15, 2020 to identify randomized controlled trials (RCTs) that compared routine second-look endoscopy with no planned second-look endoscopy in patients with acute UGIB due to PUD...

BACKGROUND AND AIMS: Patient-reported experience measures (PREMs) assessing the tolerability of endoscopic procedures are scarce. In this study, we designed and validated a PREM to assess tolerability of endoscopy using conscious sedation. METHODS: The patient-reported scale for tolerability of endoscopic procedures (PRO-STEP) consists of questions within 2 domains and is administered to outpatients at discharge from the endoscopy unit. Domain 1 (intraprocedural) consists of 2 questions regarding discomfort/pain and awareness, whereas Domain 2 (postprocedural) consists of 4 questions including pain, nausea, distention and either throat or anal pain...

BACKGROUND AND AIMS: Major limitations of conventional EMR (C-EMR) include high rates of polyp recurrence and low en-bloc resection rates, especially for lesions >20 mm in size. Underwater EMR (U-EMR) has emerged as an alternate technique for en-bloc resection of larger lesions. We conducted a systematic review and meta-analysis comparing efficacy and safety of the 2 techniques. METHODS: Multiple databases were searched through June 2020 for studies that compared outcomes of U-EMR and C-EMR for colorectal lesions...

BACKGROUND AND AIMS: Portal pressure can be used to identify subjects with chronic liver disease who have progressed to cirrhosis. Portal pressure can also provide accurate prognostication for patients with cirrhosis. However, there are no practical means for assessment of portal pressure. Although it is well-established that gastric mucosal blood supply increases in patients with cirrhosis, this has been difficult to reproducibly quantify. Our group developed a novel spectroscopic technology called spatially resolved subdiffuse reflectance spectroscopy (SRSRS) that enables quantification of mucosal microcirculation...

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BACKGROUND AND AIMS: Gastroparesis (GP) is a multifactorial disease associated with a large burden on the healthcare systems. Pyloric-directed therapies including G-POEM can be effective improve patient quality of life and symptom severity. We report on the safety and efficacy of G-POEM and its impact on the quality of life of patients managed at a large referral center. METHODS: Consecutive patients with confirmed GP referred for G-POEM due to failure of medical therapy were included...

BACKGROUND AND AIMS: Buried Barrett's mucosa is defined as intestinal metaplasia that is "buried" under the normal-appearing squamous epithelium. This can occur in Barrett's esophagus with or without previous endoscopic therapy. Dysplasia and neoplasia within buried Barrett's mucosa have also been reported. However, endoscopic features of buried Barrett's mucosa have not been described. At our tertiary referral center for Barrett's esophagus, several endoscopic features have been observed in patients who were found to have buried Barrett's mucosa on histology...

BACKGROUND AND AIMS: To determine the incidence, risk factors, and treatment outcomes of Dieulafoy's lesion of the upper gastrointestinal tract (UDL) hemorrhage among adult patients in the United States. METHODS: UDL and non-Dieulafoy upper gastrointestinal bleeding (UGIB) were identified from the Nationwide Inpatient Sample and Nationwide Readmission Database using ICD-10-CM and PCS codes. Multivariate logistic (binary) and linear (continuous) regressions were used to model dependent variables...

BACKGROUND AND AIMS: Duodenal mucosal resurfacing (DMR) is an endoscopic intervention in which the duodenal mucosa is ablated by hydrothermal energy. DMR improves glycemic control in patients with type 2 diabetes (T2D), most likely by altered duodenal signaling leading to insulin sensitization. We studied whether we could discontinue insulin use in T2D patients by combining DMR with glucagon-like peptide-1 receptor agonism (GLP-1RA) and lifestyle counseling. METHODS: Single-arm, single-center feasibility study in 16 insulin treated T2D patients (HbA1c ≤8...

There is a growing body of literature on the importance of provider gender on patient-related metrics, including satisfaction, adherence, follow-up, and health-related outcomes. Studies have shown that female patients are more likely to factor gender when choosing their physicians than male patients, and are much more likely to choose female physicians when provided the option of selecting providers. Early studies in this field have consistently demonstrated a significant gender preference for female endoscopists by female patients...

BACKGROUND AND AIMS: To compare the efficacy and safety between endoscopic radiofrequency ablation (RFA) and stent placement alone in patients with unresectable extrahepatic biliary cancer (EBC). METHODS: In this randomized controlled trial, patients with locally advanced or metastatic cholangiocarcinoma (CCA) or ampullary cancer (AC) who were unsuitable for surgery were recruited from 3 tertiary centers. Eligible patients were randomly assigned to the RFA plus plastic stent placement (RFA group) or the plastic stent placement alone group (stent placement alone group) in a 1:1 ratio...

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No abstract text is available yet for this article.

BACKGROUND AND AIMS: Although molecular analysis of pancreatic cyst fluid may aid pancreatic cyst classification, clinical practice remains highly variable. Therefore, we performed a systematic review and meta-analysis to evaluate the diagnostic performance of K-ras and G-nas mutations in EUS-acquired pancreatic cyst fluid for diagnosis of intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic lesions (MCLs). METHODS: Individualized searches were developed in accordance with PRISMA and MOOSE guidelines and meta-analysis analyzed according to the Cochrane Diagnostic Test Accuracy working group methodology...