journal
https://read.qxmd.com/read/38772788/whole-body-diffusion-weighted-magnetic-resonance-imaging-for-assessment-of-the-bone-response-rate-in-patients-with-metastatic-hormone-sensitive-prostate-cancer-receiving-enzalutamide
#1
LETTER
Alberto Dalla Volta, Francesca Valcamonico, Andrea Zivi, Giuseppe Procopio, Pierangela Sepe, Gianluca Del Conte, Nunzia Di Meo, Silvia Foti, Stefania Zamboni, Caterina Messina, Eleonora Lucchini, Anna Rizzi, Marco Ravanelli, Stefano Calza, Francesca Zacchi, Giovannino Ciccone, Nazareno Suardi, Roberto Maroldi, Davide Farina, Alfredo Berruti
No abstract text is available yet for this article.
May 20, 2024: European Urology
https://read.qxmd.com/read/38772787/performance-of-4kscore-as-a-reflex-test-to-prostate-specific-antigen-in-the-g%C3%A3-teborg-2-prostate-cancer-screening-trial
#2
JOURNAL ARTICLE
Andreas Josefsson, Marianne Månsson, Kimia Kohestani, Vasiliki Spyratou, Jonas Wallström, Mikael Hellström, Hans Lilja, Andrew Vickers, Sigrid V Carlsson, Rebecka Godtman, Jonas Hugosson
BACKGROUND AND OBJECTIVE: We investigated whether adding 4Kscore as a reflex test to prostate-specific antigen (PSA) could improve the screening algorithm for prostate cancer (PC). METHODS: In the GÖTEBORG-2 PC screening trial, 38 000men (50-60 yr) were invited to PSA testing and, if elevated, followed by magnetic resonance imaging (MRI). For 571 men with PSA ≥3.0 ng/ml and evaluable outcomes, 4Kscore was calculated. The performance using a prespecified 4Kscore cutoff of 7...
May 20, 2024: European Urology
https://read.qxmd.com/read/38762392/challenges-and-opportunities-in-establishing-appropriate-intermediate-endpoints-reflecting-patient-benefit-a-roadmap-for-research-and-clinical-application-in-nonmetastatic-prostate-cancer
#3
EDITORIAL
Sabine D Brookman-May, Marc Buyse, Stephen J Freedland, Branko Miladinovic, Ke Zhang, Wolfgang P Fendler, Felix Feng, Oliver Sartor, Christopher J Sweeney
Defining meaningful endpoints for research of early-stage high-risk prostate cancer is challenging, with established measures such as overall survival and metastasis-free survival facing limitations related to feasibility and adequate reflection of patient relevance. Developing endpoints must cater to diverse perspectives across scientific, clinical, regulatory, and patient viewpoints. Endpoints such as pathological complete response, no evidence of disease, and prevention of prostate-specific antigen relapse may reflect patient benefit by accounting for diagnostic and treatment burdens...
May 17, 2024: European Urology
https://read.qxmd.com/read/38762391/the-humanitarian-impact-of-telesurgery-and-remote-surgery-in-global-medicine
#4
EDITORIAL
Vipul Patel, Jacques Marescaux, Marcio Covas Moschovas
Telesurgery is a natural evolution of robotic surgery and has potential to address health care deficiencies in underserved areas of the globe. The same expert can reach more patients on the same day via telesurgery, and emergency procedures for neurovascular and cardiac events could be performed at the appropriate time, reducing deaths and disabilities.
May 17, 2024: European Urology
https://read.qxmd.com/read/38760293/re-alonso-garcia-ruiz-carlos-macarro-francesca-zacchi-et-al-whole-body-magnetic-resonance-imaging-as-a-treatment-response-biomarker-in-castration-resistant-prostate-cancer-with-bone-metastases-the-ipromet-clinical-trial-eur-urol-in-press-https-doi-org-10-1016
#5
LETTER
https://read.qxmd.com/read/38760292/reply-to-anwar-r-padhani-frederic-lecouvet-giuseppe-petralia-and-dow-mu-koh-s-letter-to-the-editor-re-alonso-garcia-ruiz-carlos-macarro-francesca-zacchi-et-al-whole-body-magnetic-resonance-imaging-as-a-treatment-response-biomarker-in-castration-resistant-prostate
#6
LETTER
https://read.qxmd.com/read/38755049/re-external-validation-of-the-rotterdam-prostate-cancer-risk-calculator-and-comparison-with-stockholm3-for-prostate-cancer-diagnosis-in-a-swedish-population-based-screening-cohort
#7
JOURNAL ARTICLE
Christian D Fankhauser, Marian S Wettstein, Christoph Würnschimmel, Maarten van Smeden, Noel W Clarke
No abstract text is available yet for this article.
May 15, 2024: European Urology
https://read.qxmd.com/read/38749854/risk-adjusted-screening-for-prostate-cancer-defining-the-low-risk-group-by-data-from-the-probase-trial
#8
JOURNAL ARTICLE
Agne Krilaviciute, Rudolf Kaaks, Petra Seibold, Maxime de Vrieze, Jale Lakes, Jan Philipp Radtke, Markus Kuczyk, Nina N Harke, Jürgen Debus, Christoph A Fink, Kathleen Herkommer, Jürgen E Gschwend, Valentin H Meissner, Axel Benner, Glen Kristiansen, Boris Hadaschik, Christian Arsov, Lars Schimmöller, Gerald Antoch, Frederik L Giesel, Marcus Makowski, Frank Wacker, Heinz-Peter Schlemmer, Nikolaus Becker, Peter Albers
BACKGROUND: Risk-adjusted screening for prostate cancer (PCa) aims to reduce harms by less frequent retesting, especially in men at a low risk of PCa. Definitions of low risk are based mainly on studies in men starting screening at age 55-60 yr. OBJECTIVE: To identify men at age 45 yr with a low risk of PCa. DESIGN, SETTING, AND PARTICIPANTS: A population-based, risk-adjusted PCa screening trial was conducted in Germany using baseline prostate-specific antigen (PSA) starting in young men (PROBASE)...
May 15, 2024: European Urology
https://read.qxmd.com/read/38749855/re-michael-baboudjian-romain-diamand-alessandro-uleri-et-al-does-overgrading-on-targeted-biopsy-of-magnetic-resonance-imaging-visible-lesions-in-prostate-cancer-lead-to-overtreatment-eur-urol-in-press-https-doi-org-10-1016-j-eururo-2024-02-003
#9
LETTER
https://read.qxmd.com/read/38749853/insights-into-training-standards-for-robot-assisted-surgery-and-endourology-a-perspective-for-both-urologists-and-trainees
#10
EDITORIAL
Nicholas Raison, Prokar Dasgupta, Thomas Knoll
No abstract text is available yet for this article.
May 14, 2024: European Urology
https://read.qxmd.com/read/38749852/bladder-outlet-obstruction-relief-and-symptom-improvement-following-medical-and-surgical-therapies-for-lower-urinary-tract-symptoms-suggestive-of-benign-prostatic-hyperplasia-a-systematic-review
#11
REVIEW
Massimiliano Creta, Giorgio I Russo, Naeem Bhojani, Marcus J Drake, Christian Gratzke, Benoit Peyronnet, Claus Roehrborn, Kari A O Tikkinen, Jean-Nicolas Cornu, Ferdinando Fusco
BACKGROUND AND OBJECTIVE: Symptomatic benefit and urodynamic obstruction relief represent relevant outcomes of therapies for lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH). We summarized evidence from studies concurrently assessing variations in terms of symptoms severity and invasive urodynamic measures of obstruction following medical and surgical therapies for LUTS/BPH. METHODS: We performed a systematic review of PubMed, Scopus, and Web of Science in June 2023...
May 14, 2024: European Urology
https://read.qxmd.com/read/38749851/predicting-renal-function-following-nephroureterectomy-can-impact-timing-of-systemic-chemotherapy
#12
JOURNAL ARTICLE
Carlos Munoz-Lopez, Nityam Rathi, Steven C Campbell
No abstract text is available yet for this article.
May 14, 2024: European Urology
https://read.qxmd.com/read/38749850/therapy-optimization-in-the-management-of-metastatic-hormone-sensitive-prostate-cancer-insights-from-the-arasens-study
#13
EDITORIAL
Axel S Merseburger, Simon Chowdhury, Amit Bahl
No abstract text is available yet for this article.
May 14, 2024: European Urology
https://read.qxmd.com/read/38749849/tp53-mutations-emerge-as-a-critical-biomarker-in-penile-cancer-superseding-human-papillomavirus-status
#14
EDITORIAL
Jad Chahoud, Xiaoqing Yu, Andrea Necchi, Philippe E Spiess
No abstract text is available yet for this article.
May 14, 2024: European Urology
https://read.qxmd.com/read/38744635/re-clinically-important-differences-for-pain-and-urinary-symptoms-in-urological-chronic-pelvic-pain-syndrome-a-mapp-network-study
#15
JOURNAL ARTICLE
Gopal H Badlani
No abstract text is available yet for this article.
May 13, 2024: European Urology
https://read.qxmd.com/read/38744634/re-incidence-and-survival-of-secondary-malignancies-after-external-beam-radiotherapy-for-prostate-cancer-in-the-seer-database
#16
JOURNAL ARTICLE
Joseph L Chin
No abstract text is available yet for this article.
May 13, 2024: European Urology
https://read.qxmd.com/read/38744633/re-enfortumab-vedotin-and-pembrolizumab-in-untreated-advanced-urothelial-cancer
#17
JOURNAL ARTICLE
Martina Catalano, Matteo Santoni, Giandomenico Roviello
No abstract text is available yet for this article.
May 13, 2024: European Urology
https://read.qxmd.com/read/38744632/the-role-of-microsatellite-instability-dna-mismatch-repair-deficiency-and-tumor-mutational-burden-as-biomarkers-in-predicting-response-to-immunotherapy-in-castration-resistant-prostate-cancer
#18
EDITORIAL
Niklas Klümper, Viktor Grünwald, Arndt Hartmann, Michael Hölzel, Markus Eckstein
Large trials of immune checkpoint inhibitors (ICIs) in castration-resistant prostate cancer (CRPC) have mostly failed. Biomarker-selected CRPC patients, especially those with high microsatellite instability (MSI-H), mismatch repair deficiency (dMMR), or elevated tumor mutational burden (TMB), may benefit from single-agent ICIs. Despite their rarity in CRPC (∼2-5%), identification of MSI-H, dMMR, or TMB-H could improve patient selection for immunotherapy.
May 13, 2024: European Urology
https://read.qxmd.com/read/38744631/keep-it-simple-a-proposal-for-a-new-definition-of-uncomplicated-and-complicated-urinary-tract-infections-from-the-eau-urological-infections-guidelines-panel
#19
EDITORIAL
Gernot Bonkat, Florian Wagenlehner, Jennifer Kranz
The European Association of Urology Urological Infections Guidelines Panel is proposing a new classification scheme for categorizing urinary tract infections (UTIs) into uncomplicated and complicated types. This classification would provide clarity and facilitate effective clinical management of UTIs, and acknowledges the importance of addressing clinical and sex-specific nuances in the care of individual patients.
May 13, 2024: European Urology
https://read.qxmd.com/read/38744630/underactive-bladder-according-to-the-european-association-of-urology-guidelines
#20
EDITORIAL
Michael Chancellor
No abstract text is available yet for this article.
May 13, 2024: European Urology
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