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European Radiology

Aiguo Han, Yingzhen N Zhang, Andrew S Boehringer, Michael P Andre, John W Erdman, Rohit Loomba, Claude B Sirlin, William D O'Brien
OBJECTIVES: To assess inter-platform reproducibility of ultrasonic attenuation coefficient (AC) and backscatter coefficient (BSC) estimates in adults with known/suspected nonalcoholic fatty liver disease (NAFLD). METHODS: This HIPAA-compliant prospective study was approved by an institutional review board; informed consent was obtained. Participants with known/suspected NAFLD were recruited and underwent same-day liver examinations with clinical ultrasound scanner platforms from two manufacturers...
February 19, 2019: European Radiology
Akitaka Fujisaki, Takatoshi Aoki, Hidekuni Narimatsu, Chie Kuwahara, Atsushi Nozaki, Kunitaka Menuki, Akinori Sakai, Yukunori Korogi
The original version of this article, published on 03 September 2018, unfortunately contained a mistake.
February 19, 2019: European Radiology
Miguel Paja, Jose Luis Del Cura, Rosa Zabala, Igone Korta, Aitziber Ugalde, José I López
OBJECTIVE: To evaluate the performance of core-needle biopsy (CNB) in thyroid using a cohort of patients in which it was used as first choice. METHODS: Our institutional review board approved this retrospective study. We reviewed all CNB performed in our center over a period of 11 years. Ultrasound-guided CNBs were performed using a spring-loaded 18-gauge biopsy needle. We used a classification with four diagnostic categories for CNB results: insufficient, benign, follicular lesion (indeterminate), and malignant...
February 19, 2019: European Radiology
Sebastian N Nagel, Ingo G Steffen, Stefan Schwartz, Bernd Hamm, Thomas Elgeti
OBJECTIVE: The aim of this study was to compare the age-dependent diagnostic performance of clinical scores and D-dimer testing to identify patients with suspected pulmonary embolism (PE). METHODS: Consecutive patients with suspected PE referred from the emergency department for computed tomography pulmonary angiography (CTPA) were retrospectively evaluated. Diagnostic scores (classic Wells score (WS), modified WS, simplified WS, revised Geneva score (GS), simplified GS, and YEARS score) were calculated from medical records...
February 19, 2019: European Radiology
Axel Meineke, Christian Rubbert, Lino M Sawicki, Christoph Thomas, Yan Klosterkemper, Elisabeth Appel, Julian Caspers, Oliver T Bethge, Patric Kröpil, Gerald Antoch, Johannes Boos
OBJECTIVES: To evaluate machine learning (ML) to detect chest CT examinations with dose optimization potential for quality assurance in a retrospective, cross-sectional study. METHODS: Three thousand one hundred ninety-nine CT chest examinations were used for training and testing of the feed-forward, single hidden layer neural network (January 2016-December 2017, 60% male, 62 ± 15 years, 80/20 split). The model was optimized and trained to predict the volumetric computed tomography dose index (CTDIvol ) based on scan patient metrics (scanner, study description, protocol, patient age, sex, and water-equivalent diameter (DW ))...
February 19, 2019: European Radiology
Brian H H Lang, Yu-Cho Woo, Keith Wan-Hang Chiu
OBJECTIVE: High-intensity focused ultrasound (HIFU) ablation is a promising treatment for benign thyroid nodules but single application is less effective in larger-sized nodules. We aimed to assess the efficacy and safety of two sequential applications in larger-sized nodules. METHODS: Fifty patients underwent ablation of a large-sized nodule (baseline volume ≥ 20 mL and diameter ≤ 50 mm). Thirty-one (62.0%) patients underwent single application (group I) while 19 (38...
February 18, 2019: European Radiology
Tian-Ying Jia, Jun-Feng Xiong, Xiao-Yang Li, Wen Yu, Zhi-Yong Xu, Xu-Wei Cai, Jing-Chen Ma, Ya-Cheng Ren, Rasmus Larsson, Jie Zhang, Jun Zhao, Xiao-Long Fu
OBJECTIVES: The tyrosine kinase inhibitor (TKI)-sensitive mutations of the epidermal growth factor receptor (EGFR) gene is essential in the treatment of lung adenocarcinoma. To overcome the difficulty of EGFR gene test in situations where surgery and biopsy samples are too risky to obtain, we tried a noninvasive imaging method using radiomics features and random forest models. METHODS: Five hundred three lung adenocarcinoma patients who received surgery-based treatment were included in this study...
February 18, 2019: European Radiology
Mariana M Lamacie, Christian P Houbois, Andreas Greiser, Marie-Pierre Jolly, Paaladinesh Thavendiranathan, Bernd J Wintersperger
OBJECTIVES: To validate deformable registration algorithms (DRAs) for cine balanced steady-state free precession (bSSFP) assessment of global longitudinal strain (GLS) and global circumferential strain (GCS) using harmonic phase (HARP) cardiovascular magnetic resonance as standard of reference (SoR). METHODS: Seventeen patients and 17 volunteers underwent short axis stack and 2-/4-chamber cine bSSFP imaging with matching slice long-axis and mid-ventricular spatial modulation of magnetization (SPAMM) myocardial tagging...
February 15, 2019: European Radiology
Corinne Balleyguier, Julia Arfi-Rouche, Bruno Boyer, Emilien Gauthier, Valerie Helin, Ara Loshkajian, Stephane Ragusa, Suzette Delaloge
OBJECTIVES: Radiologists' visual assessment of breast mammographic density (BMD) is subject to inter-observer variability. We aimed to develop and validate a new automated software tool mimicking expert radiologists' consensus assessments of 2D BMD, as per BI-RADS V recommendations. METHODS: The software algorithm was developed using a concept of Manhattan distance to compare a patient's mammographic image to reference mammograms with an assigned BMD category. Reference databases were built from a total of 2289 pairs (cranio-caudal and medio-lateral oblique views) of 2D full-field digital mammography (FFDM)...
February 15, 2019: European Radiology
Yaou Liu, Di Dong, Liwen Zhang, Yali Zang, Yunyun Duan, Xiaolu Qiu, Jing Huang, Huiqing Dong, Frederik Barkhof, Chaoen Hu, Mengjie Fang, Jie Tian, Kuncheng Li
OBJECTIVE: To develop and validate an individual radiomics nomogram for differential diagnosis between multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD). METHODS: We retrospectively collected 67 MS and 68 NMOSD with spinal cord lesions as a primary cohort and prospectively recruited 28 MS and 26 NMOSD patients as a validation cohort. Radiomic features were extracted from the spinal cord lesions. A prediction model for differentiating MS and NMOSD was built by combining the radiomic features with several clinical and routine MRI measurements...
February 15, 2019: European Radiology
Julien Ognard, Brieg Dissaux, Karim Haioun, Michel Nonent, Jean-Christophe Gentric, Douraïed Ben Salem
This technical note describes a novel CT scan protocol that includes a non-enhanced CT, dynamic CTA, and perfusion of the whole brain and CTA of the carotid arteries using a 320-row area detector CT scanner, with a unique contrast injection and acceptable radiation exposure dose in patients presenting with acute ischemic stroke. The acquisition parameters and reconstruction parameters will be discussed including the use of model-based iterative reconstruction (MBIR), time summing (tMIP), and subtraction techniques to optimize the results of this protocol...
February 15, 2019: European Radiology
Xiaohong Ma, Jingwei Wei, Dongsheng Gu, Yongjian Zhu, Bing Feng, Meng Liang, Shuang Wang, Xinming Zhao, Jie Tian
OBJECTIVES: To develop and validate a radiomics nomogram for preoperative prediction of microvascular invasion (MVI) in patients with hepatocellular carcinoma (HCC). METHODS: The study included 157 patients with histologically confirmed HCC with or without MVI, and 110 patients were allocated to the training dataset and 47 to the validation dataset. Baseline clinical factor (CF) data were collected from our medical records, and radiomics features were extracted from the artery phase (AP), portal venous phase (PVP) and delay phase (DP) of preoperatively acquired CT in all patients...
February 15, 2019: European Radiology
Dong Ho Lee, Jeong Min Lee, Pyo Nyun Kim, Yun-Jin Jang, Tae Wook Kang, Hyunchul Rhim, Jung Wook Seo, Young Joon Lee
OBJECTIVES: To evaluate and compare clinical outcomes of two different radiofrequency ablation (RFA) methods for locally recurred hepatocellular carcinoma (LrHCC) after locoregional treatment. METHODS: Our institutional review board approved this study with a waiver of informed consent. A total of 313 patients previously treated with transarterial chemoembolization (TACE) (n = 167) and RFA (n = 146) with a single LrHCC ≤ 3 cm was included from five tertiary referral hospitals...
February 15, 2019: European Radiology
Shan-Shan Lu, Xuan Zhang, Xiao-Quan Xu, Yue-Zhou Cao, Lin Bo Zhao, Qiang-Hui Liu, Fei-Yun Wu, Sheng Liu, Hai-Bin Shi
OBJECTIVES: To compare collateral status on single-phase CT angiography (sCTA) and multiphase CT angiography (mCTA) and their ability to predict a target mismatch on CT perfusion (CTP) and clinical outcome in patients with acute ischemic stroke (AIS). METHODS: Seventy-three AIS patients with stroke onset between 5 and 15 h or with unclear onset time and occlusions in the M1/M2 segment of the middle cerebral artery and/or intracranial internal carotid artery underwent head non-contrast CT and CTP...
February 14, 2019: European Radiology
Amandine Crombé, Nicolas Alberti, Nicolas Villard, Frank Pilleul, Xavier Buy, François Le Loarer, Michèle Kind
OBJECTIVES: SMARCA4-deficient thoracic sarcoma (SMARCA4-DTS) is a recently identified aggressive subtype of sarcoma. The aim of this study was to characterize the CT imaging features of SMARCA4-DTS. METHODS: From June 2011 to May 2017, 21 adult patients with histologically proven SMARCA4-DTS were identified in the radiological database of 2 French sarcoma reference centers with at least one chest CT scan available. The locations, sizes, heterogeneity, margin definitions, and local extensions of the tumors were reported together with their impact on surrounding organs and regional and distant metastases...
February 14, 2019: European Radiology
Liang Jiang, Yu-Chen Chen, Hong Zhang, Mingyang Peng, Huiyou Chen, Wen Geng, Quan Xu, Xindao Yin, Yuehu Ma
PURPOSE: Fluid-attenuated inversion recovery vascular hyperintensity (FVH) is frequently found in stroke patients after intracranial arterial occlusion, but the prognostic value of FVH findings is unclear. We assessed whether FVH is associated with cerebral collateral status and functional outcome in patients with acute stroke patients receiving endovascular therapy. METHODS: FVH score, American Society of Interventional and Therapeutic Neuroradiology (ASITN) grade, the functional outcome at 3 months (modified Rankin Scale (mRS)), and other clinical data were collected for 37 acute stroke patients with large vessel occlusion (LVO) receiving MRI before and after endovascular therapy...
February 14, 2019: European Radiology
Pallavi Pandey, Ankur Pandey, Nannan Shao, Farnaz Najmi Varzaneh, Mounes Aliyari Ghasabeh, Manijeh Zharghampour, Pegah Khoshpouri, Daniel Fouladi, John Eng, Anne Marie O'Broin-Lennon, Marcia Canto, Ralph H Hruban, Ihab R Kamel
OBJECTIVES: To evaluate the added value of diffusion-weighted imaging (DWI) on MRI in differentiating serous from mucin-producing pancreatic cystic neoplasms (PCNs). METHODS: One hundred seventeen patients with PCN measuring ≥ 10 mm were included. Three readers independently evaluated MRI with and without the use of apparent diffusion coefficient (ADC). Logistic regression was used to analyze whether confidence scores were different with the use of different image sets...
February 14, 2019: European Radiology
Adrian P Brady, Christoph D Becker
No abstract text is available yet for this article.
February 14, 2019: European Radiology
Sameer Bhargava, Lars Andreas Akslen, Ida Rashida Khan Bukholm, Solveig Hofvind
OBJECTIVES: To explore performance measures among non-immigrants and immigrants attending BreastScreen Norway. METHODS: We analysed data from 2,951,375 screening examinations among non-immigrants and 153,026 among immigrants from 1996 to 2015. Immigrants were categorised into high- and low-incidence countries according to the incidence of breast cancer in their birth country. Performance measures, including attendance and recall rates, rates of screen-detected cancer (SDC) and interval breast cancer (IBC), positive predictive value (PPV) and histopathological tumour characteristics, were analysed...
February 14, 2019: European Radiology
Alexis Laugerette, Benedikt J Schwaiger, Kevin Brown, Lena C Frerking, Felix K Kopp, Kai Mei, Thorsten Sellerer, Jan Kirschke, Thomas Baum, Alexandra S Gersing, Daniela Pfeiffer, Alexander A Fingerle, Ernst J Rummeny, Roland Proksa, Peter B Noël, Franz Pfeiffer
OBJECTIVES: To develop and evaluate a method for areal bone mineral density (aBMD) measurement based on dual-layer spectral CT scout scans. METHODS: A post-processing algorithm using a pair of 2D virtual mono-energetic scout images (VMSIs) was established in order to semi-automatically compute the aBMD at the spine similarly to DXA, using manual soft tissue segmentation, semi-automatic segmentation for the vertebrae, and automatic segmentation for the background...
February 13, 2019: European Radiology
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