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Developmental Medicine and Child Neurology

journal
https://read.qxmd.com/read/30883735/treatment-and-re-habilitation-of-children-with-cerebral-palsy-in-india-a-scoping-review
#1
REVIEW
Pranay Jindal, Joy C Macdermid, Peter Rosenbaum, Briano Direzze, Amitesh Narayan, Sharada L Nayak
AIM: To describe the nature and extent of the literature addressing the medical and its re/habilitative management of cerebral palsy (CP) in India. METHOD: Online worldwide scholarly databases, research hosting directories, Indian publishing houses, and grey literature were used to identify papers published between 2005 and 2016. We retrieved 144 English language papers that described the medical and rehabilitative management of Indian children with CP. RESULTS: Quantitative, qualitative, and mixed research designs are published by a variety of health care professionals in India...
March 18, 2019: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/30883727/measuring-ambulation-with-wrist-based-and-hip-based-activity-trackers-for-children-with-cerebral-palsy
#2
Debra A Sala, Helyn E Grissom, Edward M Delsole, Mary Lynn Chu, David H Godfried, Surjya Bhattacharyya, Mara S Karamitopoulos, Alice Chu
AIM: To assess the accuracy of consumer available wrist-based and hip-based activity trackers in quantitatively measuring ambulation in children with cerebral palsy (CP). METHOD: Thirty-nine children (23 males, 16 females; mean age [SD] 9y 7mo [3y 5mo]; range 4-15y) with CP were fitted with trackers both on their wrist and hip. Each participant stood for 3 minutes, ambulated in a hallway, and sat for 3 minutes. The number of steps and distance were recorded on trackers and compared to manually counted steps and distance...
March 18, 2019: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/30883725/assessing-the-stability-of-functional-classifications-for-pediatric-disability
#3
Steven Hanna
No abstract text is available yet for this article.
March 18, 2019: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/30883719/ageing-and-epigenetics-linking-neurodevelopmental-and-neurodegenerative-disorders
#4
John M Starr
Epigenetics has classically been recognized as crucial to neurodevelopment and neurodevelopmental disorders. More recently its role in ageing processes, including neurodegenerative disorders has emerged, although far more research is required in this area, particularly in humans. Epigenetic processes that regulate gene expression comprise strata of DNA modification (e.g. methylation), histone modification (e.g. histone acetylation), and mRNA translation (e.g. by microRNAs). These strata are progressively more fluid whereby changes in DNA methylation may persist for many years whilst expression of microRNAs fluctuates over short periods...
March 18, 2019: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/30883717/health-coaching-for-parents-of-children-with-developmental-disabilities-a-systematic-review
#5
REVIEW
Tatiana Ogourtsova, Maureen O'Donnell, Wagner De Souza Silva, Annette Majnemer
AIM: To determine the level of evidence on the effectiveness of health coaching for parents of children with disabilities. METHOD: A systematic review approach, comprised of a comprehensive, librarian-guided literature search; transparent study selection and data extraction; quality assessment; and synthesis of sufficiently similar data (per population, intervention nature, and overall level of evidence for each outcome using standard definitions) was undertaken...
March 18, 2019: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/30868573/a-novel-classification-system-for-research-reporting-in-rare-and-progressive-genetic-conditions
#6
Clara D M van Karnebeek, Daniël Beumer, Colleen Pawliuk, Helly Goez, Sara Mostafavi, Gail Andrews, Rose Steele, Harold Siden
AIM: To create a classification system for severe, rare, and progressive genetic conditions for use in research reporting. METHOD: A modified Delphi consensus technique was used to create and reach agreement on a new system of condition categories. Interrater reliability was tested via two rounds of an online survey whereby physicians classified a subset of conditions using our novel system. Overall percentage agreement and agreement above chance were calculated using Fleiss' kappa (κ)...
March 14, 2019: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/30868564/microbiome-programming-of-brain-development-implications-for-neurodevelopmental-disorders
#7
REVIEW
Hans Forssberg
During the last decade, research on germ-free mice has discovered that the gut microbiome (i.e. the normal bacteria colonizing the gastrointestinal tract) can programme brain function and behaviour during early development. At the same time a growing number of clinical studies have shown altered gut microflora in children with autism spectrum disorder (ASD), in combination with altered bacterial metabolites and inflammatory cytokines being part of the gut-brain axis. This review covers the concept of the microbiome; how it is established during childhood; how it is affected by malnutrition; how it can programme the development of the brain through epigenetic mechanisms; which pathways are used from the gut to the brain; and assesses findings that suggest the gut microbiome may be involved in ASD and other neurodevelopmental disorders...
March 14, 2019: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/30868553/the-importance-of-maternal-immunity-in-psychiatry-and-neurodevelopment
#8
Gustavo Scola
No abstract text is available yet for this article.
March 14, 2019: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/30854648/submandibular-gland-botulinum-neurotoxin-a-injection-for-predicting-the-outcome-of-submandibular-duct-relocation-in-drooling-a-retrospective-cohort-study
#9
Saskia E Kok, Hans F J P van Valenberg, Karen van Hulst, Peter Jongerius, Corrie E Erasmus, Frank J A van den Hoogen
AIM: This study evaluated whether the effect of submandibular gland botulinum neurotoxin A (BoNT-A) injection can predict the outcome of submandibular duct relocation with sublingual gland excision (SMDR) in children with drooling. Furthermore, we compared the effectiveness of both procedures. METHOD: A retrospective cohort study was performed in 42 children and adolescents (25 males, 17 females; mean [SD] age at BoNT-A injection 11y [4], range 4-20y; mean [SD] age at SMDR 15y [4], range 7-23y) with cerebral palsy or another non-progressive developmental disability who had undergone both BoNT-A injection and SMDR for drooling...
March 10, 2019: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/30854645/long-term-prognosis-of-epilepsy-in-patients-with-cerebral-palsy
#10
Yoshiko Tsubouchi, Ayako Tanabe, Yoshiaki Saito, Hisashi Noma, Yoshihiro Maegaki
AIM: To assess the long-term natural course and prognosis of epilepsy in patients with cerebral palsy (CP). METHOD: We retrospectively collected data for 72 patients (36 males, 36 females) with CP who had epilepsy who visited our institutions between 1980 and 2015. The data from medical records, electroencephalography (EEG), and neuroimaging findings were reviewed. Time-to-event statistical analyses were performed to analyse the remission outcome and the Cox regression model was used for multivariate analyses...
March 10, 2019: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/30854642/navigating-the-genetic-landscape-of-childhood-epilepsy-a-new-perspective
#11
Amy Mctague
No abstract text is available yet for this article.
March 10, 2019: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/30854638/pain-coping-strategies-in-children-with-cerebral-palsy
#12
Emmanuelle Chaleat-Valayer, Fabienne Roumenoff, Rachel Bard-Pondarre, Christell Ganne, Stephane Verdun, Aurelie Lucet, Jean-Claude Bernard
AIM: To describe coping strategies in children and adolescents with cerebral palsy (CP), relative to age. METHOD: Patients were prospectively recruited from two paediatric rehabilitation centres in France. The Pediatric Pain Coping Inventory - French and Structured Pain Questionnaire were completed by an experienced professional for each child. RESULTS: One hundred and forty-two children with CP were included (80 males, 62 females; median age 12y; IQR=8-15y)...
March 10, 2019: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/30854631/developmental-profile-at-initial-presentation-in-children-with-infantile-spasms
#13
Samanmali P Sumanasena, Jithangi Wanigasinghe, Carukshi Arambepola, Shalini Sri Ranganathan, Eindrini Muhandiram
AIM: To describe the baseline developmental profile and influence of clinical and demographic factors on the developmental skills of infants diagnosed with infantile spasms. METHOD: Ninety-five infants (55 males, 40 females) newly diagnosed with infantile spasms were recruited for a cross-sectional, longitudinal study. All infants underwent Bayley Scales of Infant and Toddler Development assessments in the cognitive, receptive communication, expressive communication, and fine and gross motor developmental domains; they also underwent visual, auditory, and social behaviour assessments...
March 10, 2019: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/30834521/role-of-femoral-derotation-on-gait-after-selective-dorsal-rhizotomy-in-children-with-spastic-cerebral-palsy
#14
Anja Van Campenhout, Catherine Huenaerts, Liesbeth Poulussen, Sandra D Prinsen, Kaat Desloovere
AIM: To evaluate the long-term outcome of selective dorsal rhizotomy (SDR) on gait and the influence of previous femoral derotation osteotomy (FDO). METHOD: In a retrospective cohort study of 29 children (16 females, 13 males) with spastic diplegic cerebral palsy, 14 children received FDO before SDR, whereas 15 children with moderate or near-normal internal femoral rotation during gait received only SDR. Three-dimensional gait data were obtained pre-FDO, pre-SDR, 1 year post-SDR, and 3 to 5 years post-SDR, to study the Gait Profile Score (GPS), pelvic tilt, and knee and hip kinematics...
March 4, 2019: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/30828797/early-intervention-programmes-for-infants-at-high-risk-of-atypical-neurodevelopmental-outcome
#15
REVIEW
Betty Hutchon, Deanna Gibbs, Phillip Harniess, Sally Jary, Siew-Lian Crossley, Jane V Moffat, Neela Basu, Anna P Basu
The purpose of this review is to present a new framework, EI SMART (early intervention: sensorimotor development, attention and regulation, relationships, and therapist support) for identifying key components that could contribute to more effective interventions for infants at high risk of atypical neurodevelopmental outcome. We present a clinical consensus of current challenges and themes in early intervention, based on multidisciplinary group discussions, including parents of high-risk infants, supported by a literature review...
March 4, 2019: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/30828793/perception-of-impact-of-dravet-syndrome-on-children-and-caregivers-in-multiple-countries-looking-beyond-seizures
#16
Rima Nabbout, Stephane Auvin, Catherine Chiron, Elizabeth Thiele, Helen Cross, Ingrid E Scheffer, Amy L Schneider, Renzo Guerrini, Nicola Williamson
AIM: To assess the relevance and generalizability across countries of concepts of the impact of Dravet syndrome beyond seizures, as recognized by families. METHOD: Caregivers of children with Dravet syndrome in four countries (Australia [n=8]; USA, UK, and Italy [all n=4]) participated in 1-hour qualitative telephone interviews, identifying key Dravet syndrome concepts. Interviews were recorded, transcribed, and, where necessary, translated into English for thematic analysis...
March 4, 2019: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/30828785/important-report-on-cerebral-palsy-in-bangladesh-but-different-findings-compared-with-other-countries-need-further-exploration
#17
Carin Andrews, Angelina Kakooza-Mwesige, Ann-Christin Eliasson, Hans Forssberg
No abstract text is available yet for this article.
March 4, 2019: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/30775778/upper-limb-impairments-process-skills-and-outcome-in-children-with-unilateral-cerebral-palsy
#18
Remo N Russo, Pawel P Skuza, Myriam Sandelance, Peter Flett
AIM: To examine the relationships between upper limb impairments and independence in self-care (ISC) in children with unilateral cerebral palsy (CP). METHOD: One hundred and eight children with unilateral CP (46 females, 62 males; mean age 8y 7mo, SD 3y 9mo) recruited from a population register were assessed for upper limb muscle power, spasticity, sensation, motor control, and process skills, and for ISC as the functional outcome using structural equation modelling...
February 18, 2019: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/30762238/the-independent-role-of-neonatal-seizures-in-epilepsy-and-other-long-term-neurological-outcomes
#19
Carlotta Spagnoli, Francesco Pisani
No abstract text is available yet for this article.
February 14, 2019: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/30762227/a-bio-psycho-social-view-of-cerebral-palsy-friendships-reduce-mental-health-disorders
#20
Frank W Paulus
No abstract text is available yet for this article.
February 14, 2019: Developmental Medicine and Child Neurology
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