journal
https://read.qxmd.com/read/36226713/intensive-care-management-of-liver-transplant-recipients
#1
JOURNAL ARTICLE
Jody C Olson, Ram Subramanian, Constantine J Karvellas
PURPOSE OF REVIEW: Liver transplantation remains the only definitive treatment for advanced liver disease and liver failure. Current allocation schemes utilized for liver transplantation mandate a 'sickest first' approach, thus most liver transplants occur in patients with severe systemic illness. For intensive care providers who care for liver transplant recipients, a foundation of knowledge of technical considerations of orthotopic liver transplantation, basic management considerations, and common complications is essential...
October 14, 2022: Current Opinion in Critical Care
https://read.qxmd.com/read/36226709/covid-19-dealing-with-ventilator-shortage
#2
JOURNAL ARTICLE
Alessandro Santini, Antonio Messina, Elena Costantini, Alessandro Protti, Maurizio Cecconi
PURPOSE OF REVIEW: To describe different strategies adopted during coronavirus disease 2019 pandemic to cope with the shortage of mechanical ventilators. RECENT FINDINGS: Short-term interventions aimed to increase ventilator supply and decrease demand. They included: redistributing and centralizing patients, repurposing operating rooms into intensive care units (ICUs) and boosting ventilator production and using stocks and back-ups; support by the critical care outreach team to optimize treatment of patients in the ward and permit early discharge from the ICU, ethical allocation of mechanical ventilators to patients who could benefit more from intensive treatment and short term ICU trials for selected patients with uncertain prognosis, respectively...
October 14, 2022: Current Opinion in Critical Care
https://read.qxmd.com/read/36226706/transfusion-management-in-the-trauma-patient
#3
JOURNAL ARTICLE
Joshua Dilday, Meghan R Lewis
PURPOSE OF REVIEW: Transfusion of blood products is lifesaving in the trauma ICU. Intensivists must be familiar with contemporary literature to develop the optimal transfusion strategy for each patient. RECENT FINDINGS: A balanced ratio of red-blood cells to plasma and platelets is associated with improved mortality and has therefore become the standard of care for resuscitation. There is a dose-dependent relationship between units of product transfused and infections...
October 14, 2022: Current Opinion in Critical Care
https://read.qxmd.com/read/36226720/quality-safety-and-implementation-science-in-acute-kidney-care
#4
REVIEW
Oleksa G Rewa, Kianoush Kashani
PURPOSE OF REVIEW: Quality and safety are important themes in acute kidney care (AKC). There have been many recent initiatives highlighting these aspects. However, for these to become part of clinical practice, a rigorous implementation science methodology must be followed. This review will present these practices and will highlight recent initiatives in acute kidney injury (AKI), kidney replacement therapy (KRT) and recovery from AKI. RECENT FINDINGS: The 22nd Acute Disease Quality Initiative (ADQI) focused on achieving a framework for improving AKI care...
December 1, 2022: Current Opinion in Critical Care
https://read.qxmd.com/read/36226716/surging-icu-during-covid-19-pandemic-an-overview
#5
JOURNAL ARTICLE
Yaseen M Arabi, Sheila Nainan Myatra, Suzana M Lobo
PURPOSE OF REVIEW: The coronavirus disease 2019 (COVID-19) pandemic has posed great challenges to intensive care units (ICUs) across the globe. The objective of this review is to provide an overview on how ICU surging was managed during COVID-19 pandemic, with a special focus on papers published in the last 18 months. RECENT FINDINGS: From the onset of the COVID-19 pandemic, it was apparent that the biggest challenge was the inequity of access to an adequately equipped and staffed ICU bed...
October 12, 2022: Current Opinion in Critical Care
https://read.qxmd.com/read/36226707/impact-of-icu-strain-on-outcomes
#6
JOURNAL ARTICLE
Abhijit Duggal, Kusum S Mathews
PURPOSE OF REVIEW: Acute surge events result in health capacity strain, which can result in deviations from normal care, activation of contingencies and decisions related to resource allocation. This review discusses the impact of health capacity strain on patient centered outcomes. RECENT FINDINGS: This manuscript discusses the lack of validated metrics for ICU strain capacity and a need for understanding the complex interrelationships of strain with patient outcomes...
October 12, 2022: Current Opinion in Critical Care
https://read.qxmd.com/read/36194146/covid-19-associated-aki
#7
JOURNAL ARTICLE
Kenki Matsumoto, John R Prowle
PURPOSE OF REVIEW: While it is now widely established acute kidney injury (AKI) is a common and important complication of coronavirus disease (COVID-19) disease, there is marked variability in its reported incidence and outcomes. This narrative review provides a mid-2022 summary of the latest epidemiological evidence on AKI in COVID-19. RECENT FINDINGS: Large observational studies and meta-analyses report an AKI incidence of 28-34% in all inpatients and 46-77% in intensive care unit (ICU)...
October 4, 2022: Current Opinion in Critical Care
https://read.qxmd.com/read/36194128/intra-abdominal-hypertension-and-abdominal-compartment-syndrome
#8
JOURNAL ARTICLE
Jan J De Waele
PURPOSE OF REVIEW: Intra-abdominal hypertension (IAH) has been acknowledged as an important contributor to organ dysfunction in critically ill patients, both in surgical and medical conditions. As our understanding of the pathophysiology evolves, risk factors are better recognized, preventive measures can now be implemented and therapeutic interventions tailored to the physiology of the patient. In the current review, we want to highlight developing insights in the epidemiology and treatment of patients with IAH and ACS...
October 4, 2022: Current Opinion in Critical Care
https://read.qxmd.com/read/36170383/pragmatic-platform-trials-to-improve-the-outcome-of-patients-with-acute-kidney-injury
#9
JOURNAL ARTICLE
Roberta T Tallarico, Ary S Neto, Matthieu Legrand
PURPOSE OF REVIEW: There is an important need for diagnostic strategies and treatment among patients with acute kidney injury (AKI). Classical randomized clinical trials have generated relevant results in AKI but are associated with shortcomings, such as high costs and sometimes lack of generalizability. In this minireview, we discuss the value and limits of pragmatic trials and platform trials for AKI research. RECENT FINDINGS: The implementation of pragmatic and platform trials in critical care settings has generated relevant clinical evidence impacting clinical practice...
September 29, 2022: Current Opinion in Critical Care
https://read.qxmd.com/read/36170062/fundamental-drivers-of-nurses-experiences-of-icu-surging-during-the-coronavirus-disease-2019-covid-19-pandemic
#10
JOURNAL ARTICLE
Ruth Endacott, Stijn Blot
PURPOSE OF REVIEW: Nurses working in intensive care units have been heavily impacted by the coronavirus disease 2019 (COVID-19) pandemic. This review summarizes the current state of the evidence regarding intensive care nurses experience of the pandemic. RECENT FINDINGS: The pandemic has had an impact on: nursing workload, the organization of nurse staffing, experiences of staff redeployed into ICU, nurses' perceptions of the safety and quality of patient care, and staff health...
September 29, 2022: Current Opinion in Critical Care
https://read.qxmd.com/read/36044290/subphenotypes-of-acute-kidney-injury-in-children
#11
JOURNAL ARTICLE
Katja M Gist, Dana Fuhrman, Natalja Stanski, Shina Menon, Danielle E Soranno
PURPOSE OF REVIEW: The purpose of this review is to describe acute kidney injury (AKI) phenotypes in children. RECENT FINDINGS: AKI is a heterogenous disease that imposes significant morbidity and mortality on critically ill and noncritically ill patients across the age spectrum. As our understanding of AKI and its association with outcomes has improved, it is becoming increasingly apparent that there are distinct AKI subphenotypes that vary by cause or associated conditions...
September 29, 2022: Current Opinion in Critical Care
https://read.qxmd.com/read/36302199/neurotrauma
#12
JOURNAL ARTICLE
Grace Niziolek, Danielle K Sandsmark, Jose L Pascual
PURPOSE OF REVIEW: This review will highlight the latest research relevant to the clinical care of traumatic brain injury (TBI) patients over the last 2 years while underscoring the implications of these advances in the understanding of diagnosis, treatment, and prognosis of TBI. RECENT FINDINGS: Brain tissue oxygenation monitoring can identify hypoperfusion as an adjunct to intracerebral pressure monitoring. Multiple biomarker assays are now available to help clinicians screen for mild TBI and biomarker elevations correlate with the size of intracranial injury...
December 1, 2022: Current Opinion in Critical Care
https://read.qxmd.com/read/36302198/coronavirus-disease-2019-aftermath-psychological-trauma-in-icu-healthcare-workers
#13
REVIEW
Sarah Wahlster, Christiane Hartog
PURPOSE OF REVIEW: We aim to describe the extent of psychological trauma and moral distress in healthcare workers (HCW) working in the intensive care unit (ICU) during the coronavirus disease 2019 (COVID-19) pandemic. Specifically, we review reports on prevalence of mental health symptoms, highlight vulnerable populations and summarize modifiable risk factors associated with mental health symptoms in ICU HCW. RECENT FINDINGS: The pandemic has resulted in a multitude of closely intertwined professional and personal challenges for ICU HCW...
December 1, 2022: Current Opinion in Critical Care
https://read.qxmd.com/read/36302197/lung-transplantation-in-patients-with-lung-disease-secondary-to-coronavirus-disease-2019-infection
#14
REVIEW
Diego Avella, Ankit Bharat
PURPOSE OF REVIEW: In this article, we describe preoperative patient selection and outcomes of patients with lung disease secondary to infection from COVID-19 who receive lung transplantation. RECENT FINDINGS: Lung transplants for patients with lung disease secondary to infection from COVID-19 have been performed successfully in over 200 patients in the United States. The preoperative course of these patients is somewhat atypical in comparison with patients who have had lung transplants related to chronic lung diseases, where there are more traditional indications for lung transplants...
December 1, 2022: Current Opinion in Critical Care
https://read.qxmd.com/read/36302196/selection-criteria-and-triage-in-extracorporeal-membrane-oxygenation-during-coronavirus-disease-2019
#15
REVIEW
Pasquale Nardelli, Anna Mara Scandroglio, Maria Elena De Piero, Silvia Mariani, Roberto Lorusso
PURPOSE OF REVIEW: Coronavirus disease 2019 (COVID-19) pandemic changed the way we had to approach hospital- and intensive care unit (ICU)-related resource management, especially for demanding techniques required for advanced support, including extracorporeal membrane oxygenation (ECMO). RECENT FINDINGS: Availability of ICU beds and ECMO machines widely varies around the world. In critical conditions, such a global pandemic, the establishment of contingency capacity tiers might help in defining to which conditions and subjects ECMO can be offered...
December 1, 2022: Current Opinion in Critical Care
https://read.qxmd.com/read/36302195/providing-respiratory-and-ventilation-care-in-the-face-of-shifting-evidence-current-opinion-in-critical-care
#16
REVIEW
Benedetta Giammarioli, Karen E A Burns, Bhakti K Patel, Michael C Sklar
PURPOSE OF REVIEW: To review the clinical problem and noninvasive treatments of hypoxemia in critically-ill patients with coronavirus disease 2019 pneumonia and describe recent advances in evidence supporting bedside decision making. RECENT FINDINGS: High-flow nasal oxygen and noninvasive ventilation, along with awake prone positioning are potentially helpful therapies for acute hypoxemic respiratory failure. High-flow nasal oxygen therapy has been widely implemented as a form of oxygen support supported by prepandemic randomized controlled trials showing possible benefit over noninvasive ventilation...
December 1, 2022: Current Opinion in Critical Care
https://read.qxmd.com/read/36302194/fluid-balance-in-pediatric-critically-ill-patients-with-and-without-kidney-dysfunction
#17
REVIEW
Zaccaria Ricci, Erica Bjornstad
PURPOSE OF REVIEW: The issues of fluid balance and fluid overload are currently considered crucial aspects of pediatric critically ill patients' care. RECENT FINDINGS: This review describes current understanding of fluid management in critically ill children in terms of fluid balance and fluid overload and its effects on patients' outcomes. The review describes current evidence surrounding definitions, monitoring, and treatment of positive fluid balance. In particular, the review focuses on specific patient conditions, including perioperative cardiac surgery, severe acute respiratory failure, and extracorporeal membrane oxygenation therapy, as the ones at highest risk of developing fluid overload and poor clinical outcomes...
December 1, 2022: Current Opinion in Critical Care
https://read.qxmd.com/read/36302193/editorial-renal-system-section-in-current-opinion-in-critical-care-pathways-forward-for-innovation-in-acute-kidney-injury
#18
JOURNAL ARTICLE
Sean M Bagshaw
No abstract text is available yet for this article.
December 1, 2022: Current Opinion in Critical Care
https://read.qxmd.com/read/35950719/acute-mesenteric-ischaemia
#19
REVIEW
Annika Reintam Blaser, Alastair Forbes, Martin Björck
PURPOSE OF REVIEW: To summarize the recent evidence on acute mesenteric ischaemia (AMI). RECENT FINDINGS: The overall incidence of AMI is below 10/100 000 person years but increases exponentially with age. The overall mortality of AMI remains high, exceeding 50%, despite continuing progress and increasing availability of imaging and endovascular interventions. However, patients with (early) revascularization have significantly better outcomes. The majority of patients surviving the acute event are still alive at 1 year, but evidence on quality of life is scarce...
December 1, 2022: Current Opinion in Critical Care
https://read.qxmd.com/read/35942680/subphenotypes-of-acute-kidney-injury-in-adults
#20
REVIEW
Suvi T Vaara, Lui G Forni, Michael Joannidis
PURPOSE OF REVIEW: Acute kidney injury is a heterogeneous syndrome and as such is associated with multiple predisposing conditions and causes all of which affect outcomes. Such heterogeneity may conceal the potential benefit of therapies when generally applied to patients with acute kidney injury (AKI). The discovery of pathophysiology-based subphenotypes could be of benefit in allocating current and future therapies to specific groups. RECENT FINDINGS: Clinical subphenotypes group patients into categories according to predisposing factors, disease severity, and trajectory...
December 1, 2022: Current Opinion in Critical Care
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