Jakob F B Schwensen, Wolfgang Uter, Olivier Aerts, Tove Agner, Richard Brans, Magnus Bruze, Caterina Foti, Giménez-Arnau Am, Margarida Gonçalo, Cecilia Svedman, Luca Stingeni, Mark Wilkinson, Jeanne Duus Johansen
BACKGROUND: The use of methylisothiazolinone (MI) as a preservative in cosmetic products caused an alarming increase in MI contact allergy across Europe in the 2010s. This was followed by regulations of use with a total ban on leave-on (implemented in 2017) and reduced use concentrations in rinse-off cosmetics (2018). OBJECTIVE: To follow-up on the prevalence of contact allergy to MI and the related benzisothiazolinone (BIT) and octylisothiazolinone (OIT) in consecutively patch-tested patients in Europe...
July 17, 2024: Contact Dermatitis