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Contact Dermatitis

Eva Oppel, Stefanie Kamann, Franz-Xaver Reichl, Christof Högg
BACKGROUND: Glucose monitoring systems, eg Freestyle Libre (Abott) and Dexcom (Nintamed) more and more replace conventional blood sugar measurement. However, many patients experienced adverse skin reactions such as severe allergic contact dermatitis (ACD). Finally, in August 2017 the culprit allergen in Freestyle Libre, isobornyl acrylate (IBOA), was identified. OBJECTIVES: After developing ACD it is not recommended to use their glucose monitoring system anymore...
February 19, 2019: Contact Dermatitis
Myriam Mamodaly, Olivier Dereure, Nadia Raison-Peyron
A 61-year-old patient was referred for a one-year history of relapsing itchy erythematous and vesicular lesions on the dorsa of the hands progressively extending to the neck, the neckline and the face (fig 1).
February 18, 2019: Contact Dermatitis
Nadia Raison-Peyron, Agnès Roulet, Olivier Dereure
A 56-year-old female patient was referred for itchy face dermatitis of a few months duration (fig 1). She had had allergic contact dermatitis to cheap jewellery and to an antifungal cream (Kétoderm) and was regularly using cosmetics for vascular rosacea. This article is protected by copyright. All rights reserved.
February 18, 2019: Contact Dermatitis
Linda J Bingham, Mei M Tam, Amanda M Palmer, Jennifer L Cahill, Rosemary L Nixon
BACKGROUND: Lavender is commonly used in aromatherapy and in a broad range of personal and household products. It has been identified as a contact sensitizer and has been reported to cause allergic contact dermatitis (ACD). OBJECTIVES: To report our experience with contact allergy and ACD to lavender and to raise awareness of lavender as a potential contact allergen. METHOD: A retrospective database review was performed of patients attending patch testing clinics at the Skin and Cancer Foundation, Victoria, Australia, from January 1, 1993 to December 31, 2017...
February 18, 2019: Contact Dermatitis
Kate Wicks, Clare Stretton, Amy Popple, Lorna Beresford, Jason Williams, Gavin Maxwell, John P Gosling, Ian Kimber, Rebecca J Dearman
BACKGROUND: There is considerable interest in understanding the immunological variables that have the greatest influence on the effectiveness of sensitization by contact allergens, particularly in the context of developing new paradigms for risk assessment of novel compounds OBJECTIVES: To examine the relationship between patch test score for 3 different contact allergens and the characteristics of T-cell responses. PATIENTS/MATERIALS/METHODS: A total of 192 patients with confirmed nickel, p-phenylenediamine (PPD) or methylisothiazolinone allergy were recruited from the Contact Dermatitis Investigation Unit at Salford Royal Hospital...
February 18, 2019: Contact Dermatitis
Martin Mowitz, Anne Herman, Marie Baeck, Marléne Isaksson, Annarita Antelmi, Nils Hamnerius, Ann Pontén, Magnus Bruze
BACKGROUND: Isobornyl acrylate (IBOA) has recently been identified as one sensitizer in the FreeStyle Libre glucose sensor. Analyses by gas chromatography-mass spectrometry (GC-MS) have indicated the presence of N,N-dimethylacrylamide (DMAA) in the sensor. MATERIAL AND METHODS: Seven patients were referred for patch testing after developing skin reactions when using FreeStyle Libre. All patients were patch-tested with IBOA and DMAA. Two patients were tested with adhesive patches which had been removed from the sensors "as is" and two patients were tested with acetone extracts of materials from the sensor...
February 18, 2019: Contact Dermatitis
Pauline Machet, Diane Marcé, Youssef Ziyani, Marion Dumont, Hélène Cornillier, Annie-Pierre Jonville-Bera, Laurent Machet
Immediate hypersensitivity reactions to iodinated contrast media (ICM) are rare and occur within 1 hour after infusion, but also up to 7 days later. This article is protected by copyright. All rights reserved.
February 14, 2019: Contact Dermatitis
Khaoula Ameur, Monia Youssef, Hichem Belhadjali, Yosra Soua, Mouna Korbi, Mohamed A Henchi, Jameleddine Zili
Acute generalized exanthematous pustulosis (AGEP) is a severe eruption characterized by numerous non-follicular sterile pustules on an erythematous background. AGEP is mostly caused by systemic drugs mainly antibiotics. Others causes of AGEP, such as contact with mercury, spider bites and viral infection had been described.1 This article is protected by copyright. All rights reserved.
February 12, 2019: Contact Dermatitis
Monica Corazza, Valeria Scuderi, Giulia Toni, Antonio Ascari Raccagni, Alessandro Borghi
Phytotherapeutic remedies can be responsible for allergic and irritant contact dermatitis and even chemical burns (1). We report a case of irritant contact dermatitis due to alcoholic extract from Juglans regia leaves. This article is protected by copyright. All rights reserved.
February 11, 2019: Contact Dermatitis
Eriko Shinkawa, Ken Washio, Saori Tatsuoka, Atsushi Fukunaga, Kazuhiko Sakaguchi, Chikako Nishigori
FreeStyle Libre (Abbott Diabetes Care, Witney, UK) is a novel glucose sensor that enables the monitoring of interstitial glucose levels 24 hours a day [1], however, it contains the allergen isobornyl acrylate (IBOA; CAS no. 5888-33-5) [2]. This article is protected by copyright. All rights reserved.
February 7, 2019: Contact Dermatitis
Andac Salman, Gizem Demir, Ozlem Apti
Methylchloroisothiazolinone/methylisothiazolinone (MCI/MI, eg Kathon CG), and MI are widely available preservatives mainly used in cosmetic and household products. Following a worldwide increase in contact allergy to MCI/MI and MI, regulatory measures have been implemented.1 Although a decrease in contact sensitization has been reported, MCI/MI and MI are still a frequent cause of contact dermatitis and unexpected sources of exposure may be encountered in clinical practice.2 Herein, we report three children with allergic contact dermatitis due to MCI/MI and/or MI following exposure to a homemade play material called "slime"...
February 6, 2019: Contact Dermatitis
Nils Hamnerius, Ann Pontén, Jonas Björk, Christina Persson, Ola Bergendorff
BACKGROUND: Dermatitis caused by occupational contact allergy to rubber additives like diphenylguanidine (DPG) in medical gloves is a hazard in healthcare workers. The exposure time to medical gloves as well as the number of gloves used per day vary. Use of alcoholic skin disinfectants before glove donning is mandatory. OBJECTIVES: The aim of the study was to assess if skin exposure to the rubber accelerator DPG released from glove material is influenced by alcoholic hand disinfectants, time and pH...
February 6, 2019: Contact Dermatitis
Francisco Gil, Margarida Rato, Ana Monteiro, Joana Parente, João Aranha
Allergic reactions to tin were previously reported in the literature (1,2). True cases of allergic contact dermatitis, however, are very rare. This article is protected by copyright. All rights reserved.
February 3, 2019: Contact Dermatitis
Ewa Young, Klaus E Andersen, Magnus Bruze, Ana Giménez-Arnau, Katrine Ross-Hansen, Jeanne D Johansen, Jakob Torp Madsen, Erik Zimerson, Cecilia Svedman
BACKGROUND: It is discussed if routinely patch testing p-phenylenediamine (PPD) 1.0 % petrolatum is safe due to the risk of patch test sensitization. Late appearing patch test reactions may reflect patch test sensitization, but may also be due to a low degree of pre-existing sensitization. OBJECTIVES: The aim of this study was to follow the positive patch test reactions to PPD and its salt PPD-dihydrochloride (PPD-DHC) to characterize reaction patterns concerning time and dose in PPD-sensitized individuals...
January 26, 2019: Contact Dermatitis
Coline Jaulent, Olivier Dereure, Nadia Raison-Peyron
A 33-year-old female with a history of atopic dermatitis and seasonal rhino-conjunctivitis was referred to investigate eczema. The atopic dermatitis had been active since infancy, then ceased during her teenage years but relapsed starting with the age of 25, mainly on the hands. She reported a recent flare up of inflammatory skin lesions on her chest, arms and face after applying a moisturizing cream to attenuate atopic skin-related dryness on these areas. This article is protected by copyright. All rights reserved...
January 25, 2019: Contact Dermatitis
Sanjeev Handa, Geeti Khullar, Arnab Pal, Parul Kamboj, Dipankar De
BACKGROUND: There are no Indian studies on the association between filaggrin mutations and any dermatosis, including hand eczema. OBJECTIVES: To determine the prevalence of filaggrin mutations in Indian hand eczema patients and examine associations between such mutation and any etiologic type of hand eczema. MATERIALS AND METHODS: A total of 163 patients and 86 controls were included. Patients were categorized into etiologic subtypes of hand eczema, filaggrin polymorphisms (S2889X, 2282del4, R501X and Q2417X) determined in patients and controls and correlated with subtypes...
January 25, 2019: Contact Dermatitis
K Nichol, R Copes, K Kersey, J Eriksson, Dorothy L Holness
BACKGROUND: Healthcare workers are at an increased risk for occupational contact dermatitis due to wet work exposure. Early detection and management improves outcomes. While several diagnostic tools are available, none are appropriate for rapid screening. OBJECTIVES: To assess the validity and feasibility of the Hand Dermatitis Screening Tool in the acute healthcare sector. METHODS: Screening of 508 employees at three hospitals in Ontario, Canada was done using the Hand Dermatitis Screening Tool either by an occupational health nurse (OHN, N=225) or by self-administration (N=283)...
January 24, 2019: Contact Dermatitis
Yassaman Alipour Tehrany, Sandrine Quenan, Aurélie Bugey, Pierre Piletta
Homemade slime is a new growing toy trend among children. We report 2 cases of hand dermatitis due to slime with analytical detection of isothiazolinones in slime and glue. This article is protected by copyright. All rights reserved.
January 24, 2019: Contact Dermatitis
Bertrand S Y Lian, John P McFadden, Shan X Lee
A 27-year-old Caucasian woman presented with an annular dermatitis on the flexor aspect of her right wrist. She had originally developed dermatitis on her left wrist, as she thought due to an allergic reaction to a metal watch and watch strap which she had recently acquired. This article is protected by copyright. All rights reserved.
January 24, 2019: Contact Dermatitis
Victoria H Arrandale, Dorothy L Holness
BACKGROUND: Patch testing is the key diagnostic test for diagnosing allergic contact dermatitis, but there is limited information about the use of patch testing at the population level. OBJECTIVES: To utilize Ontario Health Insurance Plan (OHIP) data to analyse trends in the rate of patch testing in Ontario. METHODS: Patch test billing data submitted to the OHIP between 1992 and 2014 was analysed. Two patch test billing codes were investigated, one for work-related testing (G198) and one for non-work-related testing (G206)...
January 24, 2019: Contact Dermatitis
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