Parita V Patel, Sherry Livingston, Jorge L Rakela, R Todd Stravitz, Adrian Reuben, Nathan M Bass, Shannan R Tujios, Anne M Larson, Norman L Sussman, Jody A Rule, Valerie L Durkalski-Mauldin, William M Lee, Daniel R Ganger
BACKGROUND: The etiology of acute liver failure (ALF) remains one of the most important factors in determining prognosis and predicting outcomes. In a significant proportion of ALF cases, however, the etiology remains unknown and is categorized as indeterminate ALF (IND-ALF). In this study, we summarize findings from patients with IND-ALF from 32 transplant centers across the United States, and we compare laboratory, prognostic, and outcome data for patients with IND-ALF. METHODS: Between 1998 and 2019, 3364 adult patients with ALF or acute liver injury (ALI) from 32 liver transplant centers were enrolled in the ALFSG registry...
September 13, 2023: Clinical Transplantation