Philipp E Hartrampf, Aleksander Kosmala, Sebastian E Serfling, Lena Bundschuh, Takahiro Higuchi, Constantin Lapa, Steven P Rowe, Yohji Matsusaka, Alexander Weich, Andreas K Buck, Ralph A Bundschuh, Rudolf A Werner
BACKGROUND: We aimed to evaluate the interobserver agreement rates in patients scanned with C-X-C motif chemokine receptor 4 (CXCR4)-directed PET/CT, including the rate of patients eligible for CXCR4-targeted radioligand therapy (RLT) based on scan results. METHODS: Four independent observers reviewed 50 CXCR4-targeted [68Ga]pentixafor PET/CT of patients with various solid cancers. On a visual level, the following items were assessed by each reader: overall scan impression, number of organ and lymph node (LN) metastases and number of affected organs and LN regions...
March 22, 2023: Clinical Nuclear Medicine