Journals Clinical Neurology and Neurosu...

Clinical Neurology and Neurosurgery
Shiqiang Yang, Yanwei Liu, Shiqiang Wang, Hua Peng, Feilong Yang, Xuhui Hui, Anqiang Yang
BACKGROUND: The prognosis of patients with thalamic hemorrhage is poor, and their long-term neurological impairment is heavy, which seriously affects their work and life.To comparatively analyse the efficacy and prognosis of patients with moderate hemorrhage in the thalamic region who underwent conservative treatment, stereotactic puncture surgery and neuroendoscopic surgery. METHOD: This study retrospectively analyzed hospitalization data from 139 adult patients with moderate-volume cerebral hemorrhage in the thalamo-endocapsular region...
April 24, 2024: Clinical Neurology and Neurosurgery
Anika Maí Jóhannsdóttir, Christian Bonde Pedersen, Sune Munthe, Frantz Rom Poulsen, Bjarni Jóhannsson
OBJECTIVE: Several radiological markers have been linked to clinical improvement after shunt surgery for idiopathic normal pressure hydrocephalus (iNPH). However, iNPH has no pathognomonic feature, and patients are still diagnosed as probable, possible, or unlikely cases based on clinical symptoms, imaging findings, and invasive supplementary tests. The predictive value of the disproportionately enlarged subarachnoid space hydrocephalus (DESH) score is not yet conclusively determined, but it might offer a more accurate diagnostic method...
April 23, 2024: Clinical Neurology and Neurosurgery
Ting Zhao, Meng Li, Qiuyue Yan, Juxian Gu, Lige Liu
OBJECTIVE: Acute cerebral infarction (ACI) contributes to disability and death accross the globe. Remote ischemic preconditioning (RIPC) reduces cerebral infarct size and improves neurological function in ACI. We conducted this research to reveal the effects of RIPC intervention on serum levels of microRNA-582-5p (miR-582-5p)/high mobility group box-1 protein (HMGB1), inflammation, oxidative stress and neurological function in patients with ACI. METHODS: In this study, 158 patients with ACI were prospectively selected and randomized into the control (administered symptomatic medication alone) and the RIPC (underwent RIPC of the limbs based on medication) groups, with their clinical baseline data documented...
April 21, 2024: Clinical Neurology and Neurosurgery
Korgün Ökmen, Şule Balk, Gökberk Kürşat Ülker
OBJECTIVE: Transcranial Doppler ultrasound (TDUS), computed tomography angiography (CTA), and transcranial Doppler ultrasound to detect cerebral blood flow are among the adjunctive tests in diagnosing brain death. This study aimed to investigate the effectiveness of orbital doppler ultrasound (ODUS). METHODS: This prospective, single-blind study included 66 patients for whom brain death was to be diagnosed. Primary outcome measures were ODUS measurements, Ophthalmic artery peak systolic velocity (PSV), end-diastolic velocity (EDV), and resistive indices (RI) measurements recorded during the brain death determination process...
April 21, 2024: Clinical Neurology and Neurosurgery
Aysenur Onalan
No abstract text is available yet for this article.
April 21, 2024: Clinical Neurology and Neurosurgery
Mingle Chen, Aoqi Liu, Yanwei Dang, Ning Wang, Zhitao Zhang, Huayun Chen, Chao Zhang, Sai Du, Xudong Ding, Chuhua Fu
OBJECTIVE: Accurate localization and real-time guidance technologies for cerebral hematomas are essential for minimally invasive procedures, including minimally invasive hematoma puncture and drainage, as well as neuroendoscopic-assisted hematoma removal. This study aims to evaluate the precision and safety of a self-developed laser-guided device in localizing and guiding hematoma punctures in minimally invasive surgery for intracerebral hemorrhage (ICH). METHODS: We present the components of the device and its operational procedures...
April 21, 2024: Clinical Neurology and Neurosurgery
Bharath M M, Mahesh Jhadav, Vivek Singh, Vimal Kumar Paliwal
Thunderclap headache is a sudden severe headache with onset to peak within one minute. Multiple excruciating, short-lived thunderclap headaches over a few days to weeks are highly suggestive of reversible cerebral vasoconstriction syndrome (RCVS). RCVS can be primary or secondary to several factors, but it is rarely described after neuro-endovascular procedures using onyx material. A 10-year-old child presented with RCVS heralded by recurrent thunderclap headache following endovascular embolization of pial arteriovenous malformation with onyx material (contains organic solvent dimethyl sulfoxide)...
April 20, 2024: Clinical Neurology and Neurosurgery
Areeba Shoaib, Fariha Arif, Maryam Khan, Tehreem Fatima, Shayan Marsia
OBJECTIVE: To assess the comparative efficacy of dexamethasone (DXM) as monotherapy in comparison to surgery among the patients of chronic subdural hematoma (CSDH). METHODS: We searched MEDLINE, PUBMED, EMBASE, and Cochrane Central Register of Controlled Trials databases from inception till September 2023. Data was extracted, pooled and analyzed from all the studies that assessed the comparative efficacy of DXM as monotherapy in contrast with surgery as the primary treatment of CSDH...
April 18, 2024: Clinical Neurology and Neurosurgery
Carlos Alberto Rodríguez Aceves, María Elena Córdoba Mosqueda, Mariano Socolovsky, Pablo Calvo Calleja, Gustavo Schenone
Attempts at body contour modifications have led to the use of different alloplastic materials that can irreversibly damage health and risk patients' lives. These modeling substances can induce a general autoimmune inflammatory response, producing a very heterogeneous clinical spectrum ranging from mild and severe systemic to local symptoms that sometimes affect peripheral nerves. We report a unique case of a tumor-like sciatic nerve impairment produced months after the injection of a modeling substance into the buttocks for esthetic purposes...
April 17, 2024: Clinical Neurology and Neurosurgery
Sohail Adnan, Sadaf Nawab, Shafi Ullah Khan, Farid Hussain
INTRODUCTION: It is still uncertain if higher thresholds on National Institute of Health Stroke Scale (NIHSS) are better predictors of large infarctions than the conventional 6-point cutoff. METHODS: We used 6-point and higher NIHSS thresholds including 8, 9, and 10-point to predict relative infarct areas, expressed as percentage of the affected hemisphere on axial brain computed tomography images, beginning at 5% with 5% increments each time until reaching the 40% cutoff for large infarctions, or achieving 100% sensitivity...
April 12, 2024: Clinical Neurology and Neurosurgery
Xiaodi Hao, Mingfang Zhu, Zhengyu Sun, Penghui Li, Qi Meng, Leilei Tan, Chen Chen, Yakun Zhang, Lihua Yang, Jiewen Zhang, Yue Huang
BACKGROUND: Stroke-induced heart syndrome is a feared complication of ischemic stroke, that is commonly encountered and has a strong association with unfavorable prognosis. More research is needed to explore underlying mechanisms and inform clinical decision making. This study aims to explore the relationship between the early systemic immune-inflammation (SII) index and the cardiac complications after acute ischemic stroke. METHODS: Consecutive patients with acute ischemic stroke were prospectively collected from January 2020 to August 2022 and retrospectively analyzed...
April 12, 2024: Clinical Neurology and Neurosurgery
Oumaima Zoulou, Moncef Maiouak, Samira El Fakir, Nabil Tachfouti, Zouhayr Souirti
PURPOSE: This study aimed to determine the factors associated with quality of life (QOL) in adult patients living with epilepsy in Morocco. METHODS: 110 patients with epilepsy aging 18 years old were interviewed using the standard and validated Moroccan version of the Quality of Life in Epilepsy inventory with 31 items (QOLIE-31). Descriptive statistics, one-way ANOVA, and multivariate regression were used for data analysis. RESULTS: The mean age of the patients was 35...
April 8, 2024: Clinical Neurology and Neurosurgery
Kerim-Hakan Sitoci-Ficici, Christoph Sippl, Anna Prajsnar, Safwan Saffour, Stefan Linsler
The sellar region, though uncommon for metastatic spread, may become more prevalent due to longer survival of patients with metastatic malignancies. Compression of adjacent vital anatomy can cause disabling symptoms and endocrine disturbances, leading to significant morbidity METHODS: This study analyzed sellar pathologies treated via endonasal approach from January 2011 to December 2021 to assess the incidence of sellar metastases. Patient demographics, presenting symptoms, radiological and histological findings, management, and outcomes were evaluated RESULTS: Among 334 patients treated during the study period, eight (2...
April 8, 2024: Clinical Neurology and Neurosurgery
Mary Angeline Luz U Hernandez, Eric Dennis C Legaspi, Kathleen Joy O Khu
BACKGROUND: Adult idiopathic occlusion of foramen of Monro (AIOFM) is a rare condition that results in hydrocephalus, and bilateral presentation is even rarer. Here we report a case of idiopathic bilateral stenosis of the foramen of Monro in an adult patient and performed a systematic literature review on the current treatment options and outcomes. METHODS: We performed a systematic review of SCOPUS, Science Direct, and PubMed databases in accordance with PRISMA guidelines...
April 7, 2024: Clinical Neurology and Neurosurgery
Hunter J Rice, Marta Bento Fernandes, Vineet Punia, Clio Rubinos, Adithya Sivaraju, Sahar F Zafar
OBJECTIVE: Post-hospitalization follow-up visits are crucial for preventing long-term complications. Patients with electrographic epileptiform abnormalities (EA) including seizures and periodic and rhythmic patterns are especially in need of follow-up for long-term seizure risk stratification and medication management. We sought to identify predictors of follow-up. METHODS: This is a retrospective cohort study of all patients (age ≥ 18 years) admitted to intensive care units that underwent continuous EEG (cEEG) monitoring at a single center between 01/2016-12/2019...
April 6, 2024: Clinical Neurology and Neurosurgery
Shanhu Xu, Susu Yu, Baojie Mao, Jiahu Yang, Peiyi Jiang, Shu Wan, Fengli Fu
OBJECTIVES: We aimed to determine whether asymptomatic carotid artery stenosis (ACS) induced cognitive impairments were related to the cholinergic hyperintensity pathway. METHODS: This cross-sectional study included patients with moderate-to-severe ACS, who were categorized into mild cognitive impairment (MCI) and normal cognition groups on the basis of Montreal Cognitive Assessment (MoCA) scores. The cholinergic pathway hyperintensity scale (CHIPS), Fazekas, and medial temporal atrophy (MTA) scores were assessed...
April 6, 2024: Clinical Neurology and Neurosurgery
Timoleon Siempis, Spyridon Voulgaris, George A Alexiou
No abstract text is available yet for this article.
April 6, 2024: Clinical Neurology and Neurosurgery
Mason M Richardson, Thomas Larrew, Steven Lin, Mohammed Alshareef, Joseph T Vasas, Libby Infinger, Ramin Eskandari
OBJECTIVE: Intracranial pressure (ICP) monitoring is commonly utilized for identifying pathologic ICP in cases of traumatic brain injury; however, its utility in hydrocephalic children has not been elucidated. Although patients with typical (pressure-active) hydrocephalus present with clear signs and/or symptoms and the need for cerebrospinal fluid (CSF) diversion is often clear, others may have arrested or pressure-compensated hydrocephalus with pathologic ICP elevation masked by ambiguous signs or are completely asymptomatic...
May 2024: Clinical Neurology and Neurosurgery
Ohju Fujita, Shigemasa Hayashi, Ryosuke Oshima, Tomoki Matsuyama, Hiroaki Tamai
No abstract text is available yet for this article.
April 2, 2024: Clinical Neurology and Neurosurgery
Junjie Wu, Chao Bai, Mingbo Hu, Qi Guan, Jianglong Li, Xinping Luan, Baofeng Yan
BACKGROUND: The effectiveness of cervical perivascular sympathectomy (CPVS) in enhancing upper limb motor function in children with cerebral palsy is unclear, and the factors that influence the effectiveness of the surgery have not been documented. OBJECTIVE: To investigate the effectiveness of CPVS in enhancing upper limb motor function in children with cerebral palsy and develop a predictive chart for potential associated adverse outcomes METHODS: The study included 187 children with cerebral palsy who underwent CPVS at the Cerebral Palsy Center, Second Affiliated Hospital of Xinjiang Medical University, between January 2018 and January 2022...
April 2, 2024: Clinical Neurology and Neurosurgery
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