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Clinical Neurology and Neurosurgery

Matthew Decker, Patricia Sacks, Joseph Abbatematteo, Edward De Leo, Meghan Brennan, Maryam Rahman
OBJECTIVE: To define the glucose values associated with an increase in complication rates in post-operative brain tumor patients. PATIENTS AND METHODS: Patients who underwent craniotomy for resection of WHO Grade III or IV glioma from 2011 to 2014 were retrospectively reviewed. Post-operative blood glucose values were recorded for post-operative day #0, #1, and #2. Medians were obtained and assessed for significance. Multivariate analysis was performed to assess patient demographics, pre-operative findings, steroid use, and blood glucose values with respect to post-operative complications and to 30-day readmission...
February 11, 2019: Clinical Neurology and Neurosurgery
Alan Villavicencio, E Lee Nelson, Sharad Rajpal, Niketna Vivek, Sigita Burneikiene
OBJECTIVE: Obesity affects not only the health of an individual but society as a whole and especially the healthcare system. Healthcare providers are faced with challenges to deliver adequate care in this resource-limited environment, assure safety, and accommodate the increasing population of overweight patients. The effects of increased body mass index (BMI) on clinical outcomes, complications, health care resource utilization, effectiveness of minimally invasive approaches, and perioperative parameters in spine surgeries have all been previously studied, but the majority of these findings are conflicting rather than conclusive...
February 11, 2019: Clinical Neurology and Neurosurgery
Noah Weingarten, Tim J Kruser, Orin Bloch
OBJECTIVES: The association of symptomatic radiation necrosis (RN) with stereotactic radiosurgery (SRS) and immune checkpoint inhibitors (ICIs) in brain metastases patients has been incompletely explored. We aim to discuss the incidence, risk factors, and prognosis of symptomatic RN in patients treated with these modalities. PATIENTS AND METHODS: We retrospectively evaluated the incidence of symptomatic RN among all patients with brain metastases treated with both SRS and an ICI at a single academic center...
February 11, 2019: Clinical Neurology and Neurosurgery
Massimo Marano, Jacopo Lanzone, Lazzaro di Biase, Alessio Pepe, Alessandro Di Santo, Vincenzo Di Lazzaro
No abstract text is available yet for this article.
February 11, 2019: Clinical Neurology and Neurosurgery
Goji Fushihara, Tomoya Kamide, Tatsuki Kimura, Ririko Takeda, Toshiki Ikeda, Yuichiro Kikkawa, Ryuichiro Araki, Hiroki Kurita
OBJECTIVE: The aim of the study was to better define the incidence of and risk factors for early seizures after repair of unruptured intracranial aneurysms in modern microsurgical techniques. PATIENTS AND METHODS: The medical records of 414 consecutive patients who underwent neck clipping of unruptured intracranial aneurysms in our institution over a 5-year period were retrospectively reviewed. Clinical and neuroimaging variables were analyzed to investigate putative predictors of perioperative seizures using multivariate logistic regression analysis...
February 8, 2019: Clinical Neurology and Neurosurgery
Veysel Burulday, Adil Doğan, Mehmet Hüseyin Akgül, Murat Alpua, Imran Çankaya
OBJECTIVE: The aim of this study was to investigate the relationship between basilar artery (BA) tortuosity, hypogenesis/agenesis of the vertebral artery (VA), and vertigo, with the use of magnetic resonance imaging (MRI). PATIENTS AND METHODS: This case-control study included patients admitted to the outpatient clinics, who were aged 18-80 years, without any known systemic diseases. All patients were evaluated with a 1.5-tesla MRI system. BA Tortuosity, VA agenesis, and VA asymmetry were noted...
February 6, 2019: Clinical Neurology and Neurosurgery
Xiaofei Wang, Chao Han, Deguang Xing, Chengwei Wang, Xuan Ding
OBJECTIVE: This study aimed to investigate the efficacy of early management for poor-grade aneurysmal subarachnoid hemorrhage (aSAH; WFNS grade IV and V), and analyze the prognostic factors. PATIENTS AND METHODS: A total of 104 consecutive patients with poor-grade aSAH from the Department of Neurosurgery, the Second Hospital of Shandong University were enrolled between January 2010 and December 2017. All these patients underwent early microsurgical clipping or endovascular coiling within three days after onset...
February 5, 2019: Clinical Neurology and Neurosurgery
Xiaodong Qin, Zhong He, Rui Yin, Yong Qiu, Zezhang Zhu
OBJECTIVE: Selecting lowest instrumented vertebra (LIV) in adolescent idiopathic scoliosis (AIS) with large lumbar curve can be difficult. Stopping the distal fusion at L3 could save more mobile lumbar segments but may increase the risk of decompensation. This study was designed to evaluate preoperative radiographic factors that were associated with the selection of either L3 or L4 as LIV in posteriorly treated AIS patients with large lumbar curve. PATIENTS AND METHODS: A total of 84 AIS patients with lumbar curve >60° were analyzed with a minimum of 2-year follow-up after posterior instrumentation with lumbar curves included in fusion...
February 5, 2019: Clinical Neurology and Neurosurgery
Yahui Zhao, Shaochen Yu, Jiaxi Li, Junlin Lu, Qian Zhang, Dong Zhang, Rong Wang, Yuanli Zhao
OBJECTIVES: Anterior cerebral artery (ACA) territory, a crucial area of intellectual development in children, is frequently involved in the progress of moyamoya disease (MMD). However, revascularization surgeries for this area are not as established as surgeries for middle cerebral artery (MCA) territory. This study aimed to describe our experience and study the effect of revascularizing ACA territory with periocranium and dural leaflets, which is referred to as 'encephalo-duro-periosteal-synangiosis (EDPS)'...
February 4, 2019: Clinical Neurology and Neurosurgery
Marie T Krüger, Yashar Naseri, Marc Hohenhaus, Ulrich Hubbe, Christoph Scholz, Jan-Helge Klingler
OBJECTIVES: The negative effects of obesity on the health and quality of life of those afflicted has become an important public concern. Previous studies have shown an association between obesity and higher rates of complications and unfavorable outcomes following spine surgery. This study is to identify peri- and postoperative complication rates as well as short-term and long-term outcomes in morbidly obese patients who underwent minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) in comparison to age-matched normal-weight patients...
February 4, 2019: Clinical Neurology and Neurosurgery
Yunwei Ou, Jinqian Dong, Liang Wu, Long Xu, Lei Wang, Baiyun Liu, Jingsheng Li, Weiming Liu
OBJECTIVE: To investigate clinical characteristics and outcomes of chronic subdural hematomas (CSDHs) in different age ranges. PATIENTS AND METHODS: A retrospective collection of data from CSDH patients ≤40 years, 41-79 years, and ≥80 years of age between August 2011 and May 2017 was performed. The differences and similarities of clinical data and outcomes among three groups were analyzed. RESULTS: A total of 1118 CSDH patients were included...
January 29, 2019: Clinical Neurology and Neurosurgery
Masashi Miyazaki, Toshinobu Ishihara, Tetsutaro Abe, Shozo Kanezaki, Naoki Notani, Masashi Kataoka, Hiroshi Tsumura
OBJECTIVE: The objective of the present study was to evaluate the effect of thoracic kyphosis formation and rotational correction by direct vertebral rotation (DVR) after the simultaneous double-rod rotation technique (SDRRT) for idiopathic scoliosis (IS). PATIENTS AND METHODS: The present study included twelve patients with IS who received SDRRT (SDRRT group) and twelve patients with IS who received DVR after SDRRT (SDRRT + DVR group). We investigated the following parameters preoperatively, postoperatively, and at postoperative 2 years: Cobb angle (PT, MT, T/L, C7-CSVL, AVT, TK (T5-12), LL(L1-S1) RSH, the angle of rotation (RAsag), percent change of RAsag and SRS22 (at postoperative 2 years only)...
January 28, 2019: Clinical Neurology and Neurosurgery
Raef F A Hafez, Osama M Fahmy, Hamdy T Hassan
OBJECTIVE: This study primarily aims to evaluate the efficacy of gamma knife surgery in controlling growth progression rate of residual clival chordoma through retrospective outcome analysis of 12 consecutive patients. PATIENTS AND METHODS: Data for 12 consecutive patients underwent GKS for post-operative residual histologically verified clival chordoma at our institution (IMC - Cairo- Egypt) from 2006 through end of 2017 were retrospectively reviewed and analyzed with mean follow-up period of 45 months (range12-120 months)...
January 25, 2019: Clinical Neurology and Neurosurgery
Erdinc Ozek, Halil Akdag, Zeynep Tosuner, Anas Abdallah, Mustafa Aziz Hatiboglu
OBJECTIVE: To assess the correlation between PHH-3 and STAT-3 in grade I and grade II meningiomas. PATIENTS AND METHODS: Medical records were retrospectively reviewed for all cranial cases which diagnosed and underwent surgery at Bezmialem Vakif University Hospital between 2012 and 2017. All cranial grade I and grade II meningioma patients constituted the core sample for this study. RESULTS: This series included 104 (69 female, 35 male) patients, with a median age of 57...
January 25, 2019: Clinical Neurology and Neurosurgery
Liping Song, Liangliang He, Qian Pei, Kejun Peng, Nan Wang, Zhaoxuan Guo, Jiaxiang Ni
OBJECTIVE: Glossopharyngeal neuralgia (GPN) is a rare disorder of the ninth cranial nerve. Percutaneous radiofrequency thermocoagulation (PRT) is an established treatment for neuropathic pain. Since PRT was first applied with GPN, only a few studies have provided detailed reports on its clinical outcomes and complications, and the number of cases was small. The aim of this study was to investigate the effects, incidence rates, and severity of adverse events of computed tomography (CT)-guided PRT in 117 patients with GPN...
January 21, 2019: Clinical Neurology and Neurosurgery
Kevin Montes, Helena Jenkinson, Onaizah B Habib, Yoshua Esquenazi, Rodrigo Hasbun
OBJECTIVES: To evaluate the utility of the corrected CSF white blood cell (WBC) count, cell index, CSF lactate, CSF glucose and a newly developed diagnostic model for the diagnosis of healthcare-associated ventriculitis or meningitis (HCAVM) in the setting of intracranial hemorrhage (ICH). PATIENTS AND METHODS: A case-control study of 111 adult patients with ICH with HCAVM (cases) or without HCAVM (controls) matched 1:2 by age, Glasgow Coma Scale (GCS), and Acute Physiology and Chronic Health Evaluation II (APACHE II) score enrolled in a large tertiary care center from 2003 to 2016...
January 21, 2019: Clinical Neurology and Neurosurgery
Fanny Xu, Anush Arakelyan, Andrew Spitzberg, Lauren Green, Paul-Henri Cesar, Anne Csere, Olive Nworie, Soma Sahai-Srivastava
OBJECTIVES: Exploratory study to investigate the effectiveness of intravenous magnesium as an abortive for status migrainosus in an outpatient infusion center, and characterize the patients who benefit from the therapy. PATIENTS & METHODS: Retrospective analysis of 234 migraine patients who received IV magnesium as a headache abortive, at the headache clinic of University of Southern California. Additional intramuscular (IM) injections for nausea (prochlorperazine, odansetron, metoclopramide) or for refractory pain (ketorolac, dexamethasone, sumatriptan, dihydroergotamine), were administered as necessary...
January 21, 2019: Clinical Neurology and Neurosurgery
Hideki Atsumi, Takatoshi Sorimachi, Mayu Kanbe, Yoichi Nonaka, Mitsunori Matsumae
OBJECTIVES: While warfarin use and the presence of the spot sign on computed tomography angiography are associated with a high frequency of hematoma enlargement and high mortality among patients with intracerebral hematomas (ICHs), the effects of various combinations of warfarin use and/or the spot sign have never been clarified. The combinations of both or either of warfarin use and/or the spot sign were used to investigate their relationships with hematoma enlargement and mortality before the introduction of prothrombin complex concentrate (PCC) treatment...
January 17, 2019: Clinical Neurology and Neurosurgery
Bing Qin, Lin Wang, Liansheng Gao, Jian Shi, Yucong Peng, Gao Chen
OBJECTIVES: The aim of this study was to analyze the clinical data concerning the loosening and tilting of the recovered bone flap after encephalo-myo-synangiosis (EMS) and explore the potential underlying mechanisms. PATIENTS AND METHODS: Clinical data of all patients who underwent an EMS procedure from January 1, 2014 to April 30, 2018 at our hospital were collected. The cases with postoperative tilting of the recovered bone flap were identified and the clinical characteristics of the patients involved were analyzed...
January 17, 2019: Clinical Neurology and Neurosurgery
Orkhan Alizada, Elife Akgun, Mehmet Yigit Akgun, Rahsan Kemerdere, Seher Naz Yeni, Taner Tanriverdi
OBJECTIVE: To see what happens on PET hypometabolism on the temporal lobe contralateral to the side of surgery in patients with bitemporal hypometabolism (BTH). PATIENTS AND METHODS: This retrospective study with prospectively defined data evaluated the pre- and post-surgical PET hypometabolism on the contralateral temporal lobe after resection of ipsilateral temporal lobe in 10 patients with BTH operated between January, 2010 and May, 2018. On PET we compared standard uptake values (SUV) and relative metabolic activities as compared to normal subjects by means of Z-scores of hypometabolism of unresected temporal lobes before and after surgery...
January 17, 2019: Clinical Neurology and Neurosurgery
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