Journals Clinical Neurology and Neurosu...

Clinical Neurology and Neurosurgery
Hrvoje Saric, Sanda Pavelin, Lidia Gavic, Kristian Jerkovic, Antonija Tadin, Ivan Galic, Zeljko Saric, Daniel Jerkovic
OBJECTIVE: Eagle syndrome or styloid process syndrome is a clinical condition of complex aetiology. Since, as a consequence of vascular compression,due to the length of the styloid process and its nearness to the internal carotid artery,it can lead to vertigo. Vertigo may be the only symptom of stylocarotid syndrome and it is extremely challenging diagnose.To the best of our knowledge, this is the first study that measures the lengths of styloid process on the Croatian population's,and possible influence of styloid process length on isolated vertigo of unknown aetiology...
November 25, 2022: Clinical Neurology and Neurosurgery
Nuray Can Usta, Cavit Boz, Murat Terzi
OBJECTIVES: The incidence of early onset multiple sclerosis (EOMS) is increasing. We therefore aimed to compare the demographic, clinical, and magnetic resonance imaging features of early onset and adult onset multiple sclerosis patients. Furthermore, the effects of age of onset were evaluated for patients who reached an expanded disability status scale (EDSS) scores of six. PATIENTS AND METHODS: This was a retrospective study of MS patient medical charts between 1977 and 2021, which were registered in the MS database...
November 23, 2022: Clinical Neurology and Neurosurgery
Salvatore J Palumbo, John W Francfort, George V Kakoulides, Brian J McHugh, Michael F McIntyre
The authors report a case in which an acute thrombosis of a pre-existing arterial stent occurs in a patient's lower extremity during a lumbar spinal fusion surgery. The event was detected by acute changes in somatosensory evoked potentials (SSEPs) which were being monitored during the procedure. The neurophysiology technologist reported a 10 % increased latency and 50 % loss of amplitude in the left posterior tibial nerve recordings. While still in the operating room, further investigation, including doppler and arteriogram, demonstrated a complete occlusion of one of the two contiguous stents within the superficial femoral artery (SFA)...
November 22, 2022: Clinical Neurology and Neurosurgery
Frederic Sampedro, Arnau Puig-Davi, Saul Martinez-Horta, Javier Pagonabarraga, Andrea Horta-Barba, Ignacio Aracil-Bolaños, Jaime Kulisevsky
BACKGROUND: Cognitive and neuropsychiatric disturbances in Parkinson's disease are as common and as disabling as its well-known motor symptoms. Even though several neural substrates for these symptoms have been suggested, to which extent these symptoms reflect cortical neurodegeneration in Parkinson's disease remains to be fully elucidated. METHODS: In a representative sample of 44 Parkinson's disease patients, the data about the following symptoms was recorded: cognitive performance, apathy, depression and anxiety...
November 21, 2022: Clinical Neurology and Neurosurgery
Aladine A Elsamadicy, Mani Ratnesh S Sandhu, Benjamin C Reeves, Josiah J Z Sherman, Samuel Craft, Mica Williams, John H Shin, Daniel M Sciubba
OBJECTIVE: As the population ages, increasing attention has been placed on identifying risk factors for poor surgical outcomes in the elderly. The aim of this study was to assess the impact of geriatric status on inpatient narcotic consumption and healthcare resource utilization in patients undergoing spinal fusion for adult spinal deformity. METHODS: A retrospective study was performed using the Premier Healthcare Database (2016-2017). All adult patients who underwent thoracic/thoracolumbar fusion for spine deformity were identified using ICD-10-CM codes...
November 19, 2022: Clinical Neurology and Neurosurgery
Madoka Imamura, Masafumi Nozoe, Hiroki Kubo, Shinichi Shimada
OBJECTIVE: Sarcopenia is associated with poor outcomes in patients with stroke. This study aimed to investigate the association between premorbid sarcopenia and neurological deterioration (ND) in patients with acute ischemic stroke. To the best of our knowledge, there have been no studies on this topic. METHODS: In this prospective longitudinal study, we assessed premorbid sarcopenia using the SARC-F questionnaire, and the incidence of ND was defined by an increase of ≥ 1 point on the National Institutes of Health Stroke Scale (NIHSS) or the occurrence of any new neurological symptoms/signs...
November 17, 2022: Clinical Neurology and Neurosurgery
Elisabetta Pupillo, Giancarlo Logroscino, Gianluigi Forloni
No abstract text is available yet for this article.
November 17, 2022: Clinical Neurology and Neurosurgery
Majid Reza Farrokhi, Seyed Reza Mousavi, Reza Rafieossadat
Idiopathic spinal cord herniation (ISCH) most commonly occurs through a ventral dural defect at the midthoracic levels with a predilection to affect middle-aged females. It can have various presentations, the most common of which are Brown-Séquard syndrome and spastic paraparesis. Due to its rarity in clinical practice, the diagnosis of ISCH can be challenging to physicians unfamiliar with this entity. We report an exceedingly rare case of ISCH at the C7-T1 intervertebral disc level in a 44-year-old male presenting with eight months of isolated unilateral sensory symptoms...
November 15, 2022: Clinical Neurology and Neurosurgery
Mohamad El Haj, Ahmed A Moustafa, Philippe Allain, Guillaume Chapelet
BACKGROUND: Verbal fluency tasks are widely used to assess cognitive and linguistic abilities in older adults. In this study, we investigated whether pupillometry can be used to measure verbal fluency in healthy older adults. METHODS: We invited 45 older adults (Mean age = 66.55 years, SD = 4.32) to perform a verbal fluency task, which involves generating as many words as possible beginning with the letter "P" for a duration of one minute. We also invited participants to perform a control task, which involves counting aloud for one minute...
November 15, 2022: Clinical Neurology and Neurosurgery
Meng Dong, Hongfei Tai, Shuo Yang, Xiaozhen Gao, Hua Pan, Zaiqiang Zhang
OBJECTIVE: Antibodies against nodal-paranodal junction proteins have been detected in some patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), which is a crucial step to define the most effective treatment strategies. In this paper, we tested the positive rates of these antibodies in CIDP and characterized the clinical and electrophysiological features of the antibodies-positive patients. METHODS: We prospectively recruited 47 patients with CIDP...
November 14, 2022: Clinical Neurology and Neurosurgery
Ruihong Liu, Yihuan Huang, Chunyi Li, Ping Wang, Yiming Wang, Lei Zhang
BACKGROUND AND PURPOSE: PPP2R5D mutations are known to cause neurodevelopmental disorders in an autosomal-dominant manner. To date, the vast majority of the reported cases in the literature have been sporadic with de novo mutations. There are no data regarding PPP2R5D mutation penetrance. We aimed to unravel the underlying genetic defects in 3 generations of a family affected by intellectual disability, neurodevelopmental delay, and facial dysmorphology. METHODS: We performed detailed clinical examinations and whole-exome sequencing in the family...
November 13, 2022: Clinical Neurology and Neurosurgery
Kai Quan, Yingjun Liu, Yun Wang, Yanlong Tian, Bin Xu, Peiliang Li, Peixi Liu, Yuan Shi, Liuxun Hu, Geng Xu, Jianfeng Luo, Jianping Song, Wei Zhu
BACKGROUND: Optimal treatment of patients with high Spetzler-Martin (S-M) grade brain arteriovenous malformations (BAVMs) remains controversial. Few studies have investigated outcomes in such patients treated in a hybrid operating room (hOR). OBJECTIVE: To examine outcomes of one-stop hybrid BAVM treatment in patients with high-grade lesions. METHODS: We prospectively enrolled patients with high-grade BAVMs (S-M grade ≥3) aged 18-65 years who underwent one-stop hybrid BAVM treatment at our hospital between October 2016 and March 2021...
November 12, 2022: Clinical Neurology and Neurosurgery
Kyril L Cole, Alexander J Kassicieh, Kavelin Rumalla, Syed Faraz Kazim, Rachel Thommen, Matthew Conlon, Meic H Schmidt, Christian A Bowers
STUDY DESIGN: Retrospective analysis of a prospectively maintained database. OBJECTIVES: To evaluate the effects of interhospital transfer (IHT) status, age, and frailty on postoperative outcomes in patients who underwent spine surgery. METHODS: The National Surgical Quality Improvement Program (NSQIP) database was queried for patients who underwent spine surgeries from 2015 to 2019 (N = 295,875). Univariate and multivariable analyses were utilized to analyze the effect of IHT on postoperative outcomes and the contribution of baseline frailty status (mFI-5 score stratified into "pre-frail", "frail", and "severely frail") on outcomes in IHT patients...
November 11, 2022: Clinical Neurology and Neurosurgery
Paola Suarez-Meade, Lina Marenco-Hillembrand, David Sabsevitz, Lela Okromelidze, B S Blake Perdikis, Wendy J Sherman, Alfredo Quinones-Hinojosa, Erik H Middlebrooks, Kaisorn L Chaichana
INTRODUCTION: There is a general lack of consensus on both anatomic definition and function of Broca's area, often localized to the pars triangularis (pT) and pars opercularis (pOp) of the left inferior frontal gyrus (IFG). Given the belief that this region plays a critical role in expressive language functions, resective surgery is often avoided to preserve function. However, the putative role of Broca's area in speech production has been recently challenged. The current study aims to investigate the plausibility of glioma resection and neurological outcomes in "Broca's area"...
November 11, 2022: Clinical Neurology and Neurosurgery
Sarah Christina Reitz, Janina Lemmer-Etzrodt, Michael Eibach, Ferdinand Bohmann, Fee Keil, Nazife Dinc, Nikhil Thakur, Jun-Suk Kang, Lutz Weise, Volker Seifert, Marcus Czabanka, Simon Baudrexel, Johanna Quick-Weller
OBJECTIVES: Deep brain stimulation (DBS) is a safe and effective treatment option for patients with movement disorders as Parkinson's disease, essential tremor and dystonia[1]. For many of these patients the need for imaging may arise in the following years after implantation. The study's aim was to get an overview of the amount of patients with a DBS system who needed an MRI after successful implantation, and if they did, whether the imaging led to a surgical consequence. MATERIALS AND METHODS: In this retrospective descriptive work patients were included if they had their DBS implantation for at least 12 months at the time of analysis...
November 9, 2022: Clinical Neurology and Neurosurgery
Ilaria Guarracino, Tamara Ius, Giada Pauletto, Marta Maieron, Serena D'Agostini, Miran Skrap, Barbara Tomasino
OBJECTIVE: The wide use of brain MRI has led to an increased diagnosis of incidental low-grade gliomas (LGGs). There is no consensus regarding the surgical treatment of incidental LGGs, nor even when we deal with a young woman who wants to plan a pregnancy. We performed a literature review on the topic of cognitive testing and pregnancy in LGGs. Results on the patients' cognitive status are poorly addressed: if, after surgery, neuropsychological deficits were to arise, this would greatly complicate the management of a child by a mother who is an oncological patient, and, moreover, has developed cognitive alterations that may compromise the abilities to look after a baby...
November 8, 2022: Clinical Neurology and Neurosurgery
Li Li, Song Luo
OBJECTIVE: This reseaech aimed to analyze the polymorphism of SOCS3 gene in patients with acute cerebral infarction (ACI), and to explore its relationship with disease progression. METHODS: A total of 310 patients with ACI were categorized into mild stroke group and moderate to severe stroke group according to the National Institute of Stroke Scale (NIHSS) score at admission. Based on NIHSS scores at 7 days after admission, patients were further divided into advanced group and non-advanced group...
November 7, 2022: Clinical Neurology and Neurosurgery
Andrea Cuschieri, Nicole Borg, Christian Zammit
BACKGROUND: At the turn of the 21st century, closed-loop deep brain stimulation (CL-DBS) systems have emerged as promising neuromodulatory treatment strategies, that integrate real-time feedback based on the brain's condition to fine-tune the stimulation being applied. CL-DBS promises numerous advantages over open-loop deep brain stimulation (OL-DBS) systems. However, no up-to-date review articles are available which characterise the clinical outcomes of CL-DBS therapy. METHODS: A systematic literature search was conducted in seven major databases with various keywords relating to CL-DBS, for non-randomised cohort studies, finalised clinical trials, case reports, and nonrandomised control trials published between 2011 and 2021...
November 6, 2022: Clinical Neurology and Neurosurgery
Jes Jose, Rohan Magoon
No abstract text is available yet for this article.
November 5, 2022: Clinical Neurology and Neurosurgery
Marcelo Bedoya-Sommerkamp, Jesús Medina-Ranilla, Victor Chau-Rodríguez, Bárbara Málaga-Espinoza, Alejandro L Escalaya, Jorge G Burneo
The Headache and Neurologic Deficits with cerebrospinal fluid Lymphocytosis syndrome (HaNDL) is a rare, benign and self-limited entity of unknown cause, diagnosed by exclusion. It usually presents with neurological deficits such as hemiparesthesia, dysphasia and hemiparesis. However, seizures are not usually associated with the clinical spectrum of this syndrome. Here we report a case of a 35 year-old male patient with multiple episodes of moderate-severe headaches with transient hemiparesthesia, dysarthria, confusion, visual hallucinations, disinhibited behavior, and a bilateral tonic-clonic seizure...
November 5, 2022: Clinical Neurology and Neurosurgery
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