Journals Clinical Neurology and Neurosu...

Clinical Neurology and Neurosurgery
Juan Du, Changhua Qu, Ziwei Xu, Zhengxin Liu, Mingxuan Lv, Dan Wang, Wenshi Wei, Yu Duan, Jun Shen
OBJECTIVES: The relationship between cognitive function and frailty in moyamoya disease (MMD) remains unclear, and the underlying mechanism is poorly understood. This study aims to investigate whether white matter hyperintensities (WMHs) mediate the association between frailty and cognitive impairment in MMD. METHODS: Patients with MMD were consecutively enrolled in our study from January 2021 to May 2023. Pre-admission frailty and cognition were assessed using the Clinical Frailty Scale (CFS) and cognitive tests, respectively...
April 9, 2024: Clinical Neurology and Neurosurgery
Majid Esmaeilzadeh, Paul Bronzlik, Hüseyin Solmaz, Manolis Polemikos, Hans E Heissler, Peter Raab, Heinrich Lanfermann, Joachim K Krauss
OBJECTIVE: Ventriculoperitoneal shunt implantation has become standard treatment for cerebrospinal fluid diversion, besides endoscopic third ventriculostomy for certain indications. Postoperative X-ray radiography series of skull, chest and abdomen combined with cranial CT are obtained routinely in many institutions to document the shunt position and valve settings in adult patients. Measures to reduce postoperative radiation exposure are needed, however, there is only limited experience with such efforts...
April 8, 2024: Clinical Neurology and Neurosurgery
Mason M Richardson, Thomas Larrew, Steven Lin, Mohammed Alshareef, Joseph T Vasas, Libby Infinger, Ramin Eskandari
OBJECTIVE: Intracranial pressure (ICP) monitoring is commonly utilized for identifying pathologic ICP in cases of traumatic brain injury; however, its utility in hydrocephalic children has not been elucidated. Although patients with typical (pressure-active) hydrocephalus present with clear signs and/or symptoms and the need for cerebrospinal fluid (CSF) diversion is often clear, others may have arrested or pressure-compensated hydrocephalus with pathologic ICP elevation masked by ambiguous signs or are completely asymptomatic...
April 6, 2024: Clinical Neurology and Neurosurgery
Junjie Wu, Chao Bai, Mingbo Hu, Qi Guan, Jianglong Li, Xinping Luan, Baofeng Yan
BACKGROUND: The effectiveness of cervical perivascular sympathectomy (CPVS) in enhancing upper limb motor function in children with cerebral palsy is unclear, and the factors that influence the effectiveness of the surgery have not been documented. OBJECTIVE: To investigate the effectiveness of CPVS in enhancing upper limb motor function in children with cerebral palsy and develop a predictive chart for potential associated adverse outcomes METHODS: The study included 187 children with cerebral palsy who underwent CPVS at the Cerebral Palsy Center, Second Affiliated Hospital of Xinjiang Medical University, between January 2018 and January 2022...
April 2, 2024: Clinical Neurology and Neurosurgery
Francisco Zarra, Dhruv Nihal Gandhi, Aakriti Karki, Bipin Chaurasia
No abstract text is available yet for this article.
April 2, 2024: Clinical Neurology and Neurosurgery
Francesca Pisano, Federico Bilotta
This brief report discusses the relationship between verbal function, disorders of consciousness, and neurological follow-up after acute brain injury. It provides valuable insights for improving the accuracy and reliability of Verbal Glasgow Coma Scale scoring in clinical practice. The report addresses the need for standardized training and underlines the importance of physiological stabilization before assessment. Clarity in communication, recognition of non-verbal cues, and serial assessments are emphasized as critical factors to reduce the Verbal Glasgow Coma Scale inconsistencies...
April 2, 2024: Clinical Neurology and Neurosurgery
Hussein Algahtani, Bader Shirah, Muhammad Imran Naseer
Vacuolar protein sorting 13 homolog D (VPS13D) gene encodes a protein involved in trafficking of membrane proteins between the trans-Golgi network and the prevacuolar compartment. This study reports a novel homozygous mutation (c.12494T>C p.Ile4165Thr) in the VPS13D gene in a Saudi female diagnosed with autosomal recessive spinocerebellar ataxia type 4 (SCAR4). The patient's clinical presentation, including progressive weakness, ataxia, and numbness, aligns with SCAR4 characteristics. The comprehensive evaluation, comprising neurological examination, brain MRI, and genetic testing, revealed distinctive features consistent with autosomal recessive inheritance...
March 30, 2024: Clinical Neurology and Neurosurgery
Facundo Villamil, Guido Caffaratti, Mauro Ruella, Lucila Domecq Laplace, Ismael Calandri, Maximiliano Darakdjian, Maximiliano Nuñez, Ruben Mormandi, Andrés Cervio
OBJECTIVE: The V3 segment of the vertebral artery (V3-VA) is at risk during diverse approaches to the craniovertebral junction. Our objective is to present a system of anatomic and topographic landmarks to identify the V3-VA during the paramedian suboccipital approach (PMSOA) with the help of minimal or basic tools. MATERIAL AND METHODS: The first was a retrospective analysis of the angiotomography (CTA) of 50 patients over 18-years old, and 9 anatomical dissections...
March 29, 2024: Clinical Neurology and Neurosurgery
Raffaele De Marco, Filippo Lacatena, Fabio Cofano, Diego Garbossa, Alessandro Fiumefreddo
OBJECTIVE: Extraparenchymal localization of neurocysticercosis (NCC) is rare in non-endemic areas. A case of mixed (intraventricular, IV, and subarachnoid basal, SAB) NCC was surgically treated using the neuroendoscope and a systematic review of the literature was performed with the aim to analyze the use of this instrument in the management of the extraparenchymal forms of the parasitic disease. MATERIALS AND METHODS: Medline and Embase databases were searched for studies where the neuroendoscope was used for the management of IV/SAB NCC cysts, either for the cerebrospinal fluid diversion or cyst removal...
March 29, 2024: Clinical Neurology and Neurosurgery
Hinpetch Daungsupawong, Viroj Wiwanitkit
No abstract text is available yet for this article.
March 27, 2024: Clinical Neurology and Neurosurgery
Aoi Shiina, Daisuke Ishikawa, Kunihiko Ishizawa, Hiroo Kasahara, Yukio Fujita, Ikuko Mizuta, Tomokatsu Yoshida, Yoshio Ikeda
This report presents a case of Alexander disease showing clinical characteristics mimicking progressive supranuclear palsy (PSP). A 67-year-old woman complaining of motor disturbance exhibited severe atrophy of medulla, spinal cord, and midbrain tegmentum, as well as periventricular hyperintensity on cerebral MRI. Genetic analysis identified a novel in-frame deletion/insertion mutation in the exon 3 of the GFAP gene. Interestingly, neurological findings and decreased striatal uptake in dopamine transporter SPECT were suggestive of PSP...
March 27, 2024: Clinical Neurology and Neurosurgery
Sara Hanaei, Seyed Farzad Maroufi, Shaghayegh Sadeghmousavi, Arshia Nejati, Abolfazl Paeinmahalli, Mohammad Amin Dabbagh Ohadi, Charles Teo
BACKGROUND: Tumors in the fourth ventricle can be critical due to the small size of the fourth ventricle, which causes symptoms to be detected even in the presence of lesser mass effects. A proper surgical approach to the fourth ventricle poses challenges due to its deep location and proximity to vital compartments within the brainstem. The two commonly used approaches to these tumors are the transvermian and telovelar approaches. METHODS: A comprehensive systematic study was conducted based on a literature search of the databases...
March 26, 2024: Clinical Neurology and Neurosurgery
Ravi Krishna Kanth, Naman Agrawal, Pratik Patel, Anka Arora, Manish Chaturvedy, Sarbesh Tiwari, Divya Aggarwal, Samhita Panda
A 63-year-old man with type 2 diabetes mellitus, alcohol consumption in moderation, and three episodes of hepatic encephalopathy presented with symmetrical lower limb distal weakness, sensory ataxia, thickened palpable nerves, mood disturbances for seven years, and a family history of schizophreniform disorders. Nerve conduction studies showed demyelinating sensorimotor polyradiculoneuropathy. CSF analysis showed mild albumino-cytological dissociation. MRI brain and lumbosacral plexus showed thickened fifth cranial nerves and lumbosacral roots...
March 26, 2024: Clinical Neurology and Neurosurgery
Jiali Xu, Yuqiong Yang, Zhizhen Gao, Tao Song, Yichuan Ma, Xiaojun Yu, Changzheng Shi
OBJECTIVE: To explore the feasibility of identifying epidermal growth factor receptor (EGFR) mutation molecular subtypes in primary lesions based on the radiomics features of lung adenocarcinoma brain metastases using magnetic resonance imaging (MRI). METHODS: We retrospectively analyzed clinical, imaging, and genetic testing data of patients with lung adenocarcinoma with EGFR gene mutations who had brain metastases. Three-dimensional radiomics features were extracted from contrast-enhanced T1-weighted images...
March 26, 2024: Clinical Neurology and Neurosurgery
Jose Pablo Fernandez V, Natalia Acosta G, Tamara Flores S, Gabriela Fernández
INTRODUCTION: Ventriculoperitoneal shunt (VPS) infection is a severe complication. Early diagnosis could help to decrease morbidity and treatment costs. Lactate has been used for the diagnosis of other central nervous system infections. The aim of this study is to determine the usefulness of lactate for the diagnosis of VPS infection. METHODOLOGY: Retrospective cohort study. Lactate was measured in patients who consulted with VPS dysfunction between May 2019 and May 2022...
March 24, 2024: Clinical Neurology and Neurosurgery
Lucía Alonso-Magdalena, Olga Carmona I Codina, Elisabet Zia, Peter Sundström, Hélène Pessah-Rasmussen
BACKGROUND: Multiple sclerosis (MS) is the most common chronic demyelinating disease of the central nervous system and the major non-traumatic cause of permanent disability in young adults. Several migration studies have been performed over the years suggesting a pattern of higher disease disability in certain ethnic groups. To our knowledge, differences in disease progression in immigrants have not been studied in Sweden before. Thus, the aims of our study were to estimate the prevalence of multiple sclerosis among first-generation immigrants in the City of Malmö and to compare differences in disease severity with the native population...
March 23, 2024: Clinical Neurology and Neurosurgery
Xing Chen, Xueni Yang, Yanqing Li, Xiaomei Zhang, Yingqian Zhu, Linjing Du, Jing Cai, Xiuqun Xu
OBJECTIVES: There is a scarcity of data regarding the effects of kinesiophobia on stroke patients with hemiplegia. Therefore, this paper aims to evaluate the level of kinesiophobia experienced by stroke patients with hemiplegia in China, examine the elements that influence it, and investigate the unique psychological experience of kinesiophobia combined with a qualitative study. METHODS: This mixed study was conducted in two steps. Four approved scales were used to evaluate a total of 163 patients: (i) Tampa Scale of Kinesiophobia, (ii) Pain Catastrophizing Scale, (iii) Self-Efficacy for Exercise Scale, and (iv) Hospital Anxiety and Depression Scale...
March 22, 2024: Clinical Neurology and Neurosurgery
Vitalij Zeiser, Farjad Khalaveh, Anna Cho, Andrea Reinprecht, Johannes Herta, Karl Rössler, Christian Dorfer
BACKGROUND: Spontaneous intracerebral hemorrhage (SICH) of the elderly is a devastating form of stroke with a high morbidity and economic burden. There is still a limited understanding of the risk factors for an unfavorable outcome where a surgical therapy may be less meaningful. Thus, the aim of this study is to identify factors associated with unfavorable outcome and time to death in surgically treated elderly patients with SICH. METHODS: We performed a single-center retrospective study of 70 patients (age > 60 years) with SICH operated between 2008 and 2020...
March 22, 2024: Clinical Neurology and Neurosurgery
Juan Carlos Martinez-Gutierrez, Bryden H Dawes, Hussein A Zeineddine, William W Wroe, Salvatore A D'Amato, Hyun Woo Kim, Michael I Nahhas, Peng Roc Chen, Spiros L Blackburn, Sunil A Sheth, Ching-Jen Chen, Ashutosh Mahapatra, Ryan S Kitagawa, Mark J Dannenbaum
BACKGROUND: Septated chronic subdural hematomas (cSDH) have high rates of recurrence despite surgical evacuation. Middle meningeal artery embolization (MMAE) has emerged as a promising adjuvant for secondary prevention, yet its efficacy remains ill-defined. METHODS: This is a retrospective review of septated cSDH cases treated at our institution. The surgery-only group was derived from cases performed before 2018, and the surgery+MMAE group was derived from cases performed 2018 or later...
March 21, 2024: Clinical Neurology and Neurosurgery
Armin Karamian, Hana Farzaneh, Mojtaba Taheri, Ali Seifi
OBJECTIVE: Traumatic brain injury (TBI) and the subsequent Post-traumatic seizure (PTS) is a growing public health concern. Generally, anti-seizure drugs (ASDs) are recommended for PTS prophylaxis and treatment. This meta-analysis aimed to review the current state of knowledge and the evidence for the efficacy and safety of Levetiracetam (LEV) on the incidence of seizure in TBI patients compared to Phenytoin (PHT). METHODS: A search was carried out based on PubMed, MEDLINE, Europe PMC database, and Cochrane Library up to November 2023...
March 20, 2024: Clinical Neurology and Neurosurgery
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