Journals Clinical Neurology and Neurosu...

Clinical Neurology and Neurosurgery
Jonathan Dallas, Kristie Q Liu, Talia A Wenger, Michelle Lin, Li Ding, Frank J Attenello, William J Mack
INTRODUCTION: COVID-19 has had innumerable impacts on the healthcare system, both by worsening patient illness and impeding effective and efficient care. Further, COVID-19 has been tied to increased rates of ischemic stroke, particularly among young patients. We utilized a national database to assess associations of COVID-19 with thrombectomy rates, mortality, and discharge disposition among stroke patients. METHODS: Patients were identified from the National Inpatient Sample (NIS, 2020)...
September 15, 2023: Clinical Neurology and Neurosurgery
Jennifer Samuelsson, Alexandros Rentzos, Araz Rawshani, Adrian Karlsson, Marcus StÄleby, Daniel Nilsson
BACKGROUND: Data on de novo aneurysm formation after treatment for intracranial aneurysms remains scarce. We studied the incidence of de novo aneurysm formation in patients who had undergone aneurysm treatment more than 18 years prior to follow-up. As it is a disease affecting a younger patient population more specific guidelines are needed when planning a follow-up regime. METHODS: The rate of de novo aneurysm formation was assessed with Magnetic Resonance Angiography (MRA) follow-up >18 years after endovascular or microsurgical treatment for an intracranial aneurysm...
September 14, 2023: Clinical Neurology and Neurosurgery
Hassan K Salamatullah, Bader Bashrahil, Abdulaziz M Alghamdi, Faisal S Alsharm, Osama A Alkulli, Ziyad Alzahrani, Ahmed Alkhiri, Saeed Alghamdi, Seraj Makkawi
BACKGROUND: Alteplase is the standard medical therapy for acute ischemic stroke (AIS) patients who present within 4.5 h of symptom onset. Tenecteplase is a modified alteplase variant with pharmacological and practical advantages over alteplase. Many trials have investigated the efficacy and safety of tenecteplase against alteplase. This systematic review and meta-analysis aimed to compare the efficacy and safety of tenecteplase to alteplase across randomized controlled trials. METHOD: Medline, Embase, and Cochrane CENTRAL were used to search the related articles until February 20, 2023...
September 9, 2023: Clinical Neurology and Neurosurgery
Sarah Ming Li Tan, Shi Hui Ong, Tseng Tsai Yeo, Vincent Diong Weng Nga, Effie Chew, Pui Kit Tam, Peijing Su, Megan Bj Ng, Hui Shi Lim, Leonard Ll Yeo, Vijay K Sharma, Ching-Hui Sia, Mervyn Jun Rui Lim, Benjamin Yong-Qiang Tan
BACKGROUND: Functional recovery and return to work (RTW) after stroke are important rehabilitation goals that have significant impact on quality of life. Comparisons of functional outcomes and RTW between ischemic stroke (IS) and hemorrhagic stroke (HS), especially among young adults with stroke, have either been limited or yielded inconsistent results. We aimed to assess functional outcomes and ability to RTW in young adults with IS and HS, specifically primary spontaneous intracranial hemorrhage (SICH)...
September 7, 2023: Clinical Neurology and Neurosurgery
Jian Hu, Fan Su, Xia Ren, Lei Cao, Chenxu Wang, Wendan Mei, Yicheng Fang, Grace Tavengana, Mingfei Jiang, Huan Wu, Yufeng Wen
OBJECTIVE: Carotid plaque instability is a risk factor for ischemic stroke, and changes in serum creatinine are associated with carotid plaque. However, the relationship between serum creatinine and carotid plaque stability is not well explained. This study aimed to interpret this relationship for clinical treatment of carotid plaque. METHODS: A total of 4363 subjects aged 29-86 from December 2013 to December 2018 were included in this study. The stability of carotid plaque was determined based on ultrasound echoes and divided into two groups: carotid plaque stable group and carotid plaque unstable group...
September 7, 2023: Clinical Neurology and Neurosurgery
Yilong Zheng, Zheting Zhang, Jiashen Zhao, Kejia Teo, Vincent Diong Weng Nga, Tseng Tsai Yeo, Mervyn Jun Rui Lim
OBJECTIVE: ABO blood type has been associated with mortality among patients with cancer, but this association has thus far not been investigated among patients with brain metastases. Hence, we aimed to investigate the association between ABO blood type and mortality among patients who underwent surgical resection of brain metastases. METHODS: A single-center retrospective study of patients who underwent surgical resection of brain metastases between 2011 and 2019 was conducted...
September 7, 2023: Clinical Neurology and Neurosurgery
Anita L Kalluri, Raymond J So, Sumil K Nair, Joshua Materi, Dorothy Wang, Niranjan Behera, Michael D Kornberg, Judy Huang, Michael Lim, Chetan Bettegowda, Risheng Xu
OBJECTIVES: While patients with concomitant trigeminal neuralgia (TN) and multiple sclerosis (MS) are understood to experience a more intractable pain phenotype, whether TN pain outcomes differ by the presenting MS subtype is not well characterized. This study's objective is to compare post-operative pain and numbness outcomes following microvascular decompression (MVD) in TN patients with either relapsing-remitting MS (RRMS) or progressive MS. METHODS: We retrospectively reviewed all TN patients who underwent MVDs at our institution from 2007 to 2020...
September 7, 2023: Clinical Neurology and Neurosurgery
Dong Won Kwack, Dong Wook Kim
BACKGROUND: Hyperammonemia can occur after acute overdose or chronic use of valproic acid (VPA). Although VPA-related hyperammonemic encephalopathy (VHE) is a rare complication of VPA therapy, early recognition of VHE and identifying its risk factors are important because VHE can lead to loss of consciousness and increased seizure frequency. PURPOSE: The purpose of our study is to evaluate the risk factors of hyperammonemia in epilepsy patients during treatment with VPA therapy...
September 6, 2023: Clinical Neurology and Neurosurgery
Qianfeng Li, Faliang Duan, Ming Luo, Zhihua Luo
OBJECTIVE: Hypertensive cerebellar hemorrhage is a severe condition in neurosurgery, associated with high disability and mortality rates. The present study compares the efficacy and outcomes of neuronavigation-assisted neuroendoscopy versus conventional microscope (craniotomy) in treating patients with hypertensive cerebellar hemorrhage. METHODS: A retrospective study was conducted by analyzing medical records of patients with hypertensive cerebellar hemorrhage treated at Wuhan No...
September 4, 2023: Clinical Neurology and Neurosurgery
Ali Seifi, Mohammad Ali Ostovan
No abstract text is available yet for this article.
September 3, 2023: Clinical Neurology and Neurosurgery
Chen Xiaoquan, Lou Yuting, Miao Pu, Cheng Haiying, Wan Zheng, Wang Ye, Yang Fan, Liang Mengmeng, Feng Jianhua
Epilepsy is one of the most common disorders in children, with an incidence rate of approximately 5%. Although an increasing number of genes have been demonstrated to be pathogenic factors in epilepsy, evidence for a potential pathogenic role of ATP6V1A remains limited. Herein, the clinical and genetic data of a 5-year-old boy who experienced seizures at 9 months of age are collected. Genetic variants are screened using whole-exome sequencing (WES), and the effects of the candidate variants are further validated at both the RNA and protein levels...
September 1, 2023: Clinical Neurology and Neurosurgery
Hu He, Fei Wang, Dejun Bao, Chaoshi Niu
OBJECTIVE: To compare the prognosis of patients with spontaneous basal ganglia intracerebral hematoma treated by endoscopic evacuation, craniotomy, or puncture aspiration. METHODS: This retrospective observational study included information from patients with basal ganglia hematoma who received craniotomy, endoscopic evacuation, or puncture aspiration in the Department of Neurosurgery of the First Affiliated Hospital of USTC between January 2016 and May 2021. Patients were grouped according to their treatment method for comparison...
September 1, 2023: Clinical Neurology and Neurosurgery
Alon Doron, Tamar Eviatar-Ribak, Aya Vituri, Shimon Shahar, Firas Fahoum, Lilach Goldstein
OBJECTIVE: A nationwide vaccination operation against Coronavirus disease 2019 (COVID-19) using the BNT162b2 mRNA vaccine commenced in Israel in December 2020. People older than 60 were prioritized, and most were vaccinated shortly after. Seizures are not infrequently attributed to the vaccine despite a lack of supporting evidence. People with epilepsy (PWE) are often reluctant to get the vaccine due to concerns of seizure aggravation. We aim to examine the effect of the vaccine effort on the frequency of both new-onset seizures and recurrent seizures in PWE...
August 29, 2023: Clinical Neurology and Neurosurgery
Jia Zhang, Jinfeng Liu, Jianjun Wang, Jing Gan
BACKGROUND: To describe the clinical characteristics of anti-NMDAR encephalitis secondary to acute necrotizing encephalopathy caused by herpes simplex virus encephalitis in infants, and aid in its early recognition, diagnosis and treatment. CASE PRESENTATION: A total of 4 infants were included; all presented with fever, seizures, and progressive disturbances of consciousness and were diagnosed with herpes simplex virus (HSV-1) encephalitis. Cerebrospinal fluid (CSF) protein levels progressively increased, and the head MRI showed necrotizing encephalopathy...
August 29, 2023: Clinical Neurology and Neurosurgery
Zobia Ansari, Youmna Rafiq, Hafsa Arif, Fatima Shahid
No abstract text is available yet for this article.
August 29, 2023: Clinical Neurology and Neurosurgery
Leonardo de Barros Oliveira, Leonardo Christiaan Welling, Fabio Alex Fonseca Viegas, Luiz Roberto Cavassola Ribas, Elcio Oscar Machinski Junior, Rubens Miguel Wesselovicz, Savio Batista, Raphael Bertani, Lucca Biolcati Palavani, Nicollas Nunes Rabelo, Eberval Gadelha Figueiredo
BACKGROUND: Ventriculoatrial shunt (VAS) is considered the second option for treating hydrocephalus, but there remains a lack of robust evidence regarding its complications profile. PURPOSE: Evaluate the complications associated with VAS. METHODS: Adhering to PRISMA guidelines, the authors searched Embase, PubMed, and Web of Science databases to identify articles reporting on the complications of VAS. Eligible articles were required to report whether complications occurred in a cohort of at least four patients...
August 26, 2023: Clinical Neurology and Neurosurgery
Hyunsun Oh, Kayeong Im, Ha-Rin Yang, Hyo Jae Kim, Yong Seo Koo, Sang-Ahm Lee
PURPOSE: We evaluated long-term seizure outcomes of antiseizure medications (ASMs) and risk factors for drug resistance in patients with adult-onset epilepsy associated with cerebral cavernous malformation (CCM). MATERIALS AND METHODS: This retrospective observational study included patients newly diagnosed with adult-onset focal epilepsy associated with CCM. Patients received individualized treatments with ASMs. All patients were followed-up for at least 2 years...
August 25, 2023: Clinical Neurology and Neurosurgery
Serena Tola, Alberto Parenti, Alice Esposito, Alessandro Della Puppa
OBJECTIVE: Superficial Middle Cerebral Vein (SMCV) is an anastomotic vein frequently exposed during surgery. Changes in the pattern of cerebral venous outflow can occur in many pathological settings. We explored the hypothesis that the growth of an intracranial tumor could determine alterations in the venous outflow. We analyzed SMCV anatomical variants in patients undergoing surgery for intracranial tumors; we furthermore focused on association with histology. METHODS: We retrospectively collected data of 120 patients undergoing surgery, 60 presenting intracranial tumor and 60 presenting cerebral aneurysms (control group)...
August 25, 2023: Clinical Neurology and Neurosurgery
Marco Pavanello, Anna Ronchetti, Ida Barretta, Paolo Moretti, Gianluca Piatelli
BACKGROUND: Intrathecal baclofen therapy (ITB) is an effective treatment for reducing spasticity but can be associated with various complications, including infection and implant malfunction. METHODS: This retrospective cohort study analyzed refill reports, complications, and functional outcomes in 40 consecutive patients with intractable spasticity or dystonia undergoing ITB. RESULTS: Among the 40 patients, 8 experienced complications, including two cases of calcification of the baclofen pump pouch and surrounding tissue, a rare complication not extensively described in the literature...
August 23, 2023: Clinical Neurology and Neurosurgery
Masaya Nakagawa, Terushige Toyooka, Satoru Takeuchi, Toru Yoshiura, Arata Tomiyama, Tomoko Omura, Yohei Otsuka, Takahito Higashi, Yasushi Kobayashi, Kojiro Wada
OBJECTIVES: Patients sometimes present with high cervical internal carotid artery (ICA) stenosis. This study demonstrates the usefulness of the transstyloid approach to expose the distal ICA by dissection of the styloid diaphragm covering the distal cervical ICA for carotid endarterectomy (CEA). In particular, the possible exposure length achieved by this approach was investigated using cadaveric heads. METHODS: The procedure of the transstyloid diaphragm approach was confirmed in 10 cadaveric heads (20 sides)...
August 22, 2023: Clinical Neurology and Neurosurgery
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