John R de Almeida, Jie Susie Su, Mirko Manojlovic Kolarski, Tra Truong, Ilan Weinreb, Bayardo Perez-Ordonez, Stephen M Smith, Ali Hosni, Snehal Patel, Cristina Valero, Bin Xu, Ronald Ghossein, Nora Katabi, Jonathan Clark, Tsu-Hui Hubert Low, Ruta Gupta, Evan M Graboyes, Joel Davies, Mary Richardson, Vishu Pasham, Rachel Jester, David P Goldstein, Shao Hui Huang, Wei Xu, Brian O'Sullivan
BACKGROUND: For oral cavity squamous cell carcinoma (OSCC), extent of extranodal extension (ENE) (minor, ≤2 mm; major, >2 mm) is differentially prognostic, whereas limitations exist with the 8th edition of American Joint Committee on Cancer/International Union Against Cancer TNM N-classification (TNM-8-N). METHODS: Resected OSCC patients at four centers were included and extent of ENE was recorded. Thresholds for optimal overall survival (OS) discrimination of lymph node (LN) features were established...
September 26, 2023: Cancer