B J van der Wilk, B M Eyck, M Doukas, M C W Spaander, E J Schoon, K K Krishnadath, L E Oostenbrug, S M Lagarde, B P L Wijnhoven, L H J Looijenga, K Biermann, J J B van Lanschot
BACKGROUND: Active surveillance has been proposed for patients with oesophageal cancer in whom there is a complete clinical response after neoadjuvant chemoradiotherapy (nCRT). However, endoscopic biopsies have limited negative predictive value in detecting residual disease. This study determined the location of residual tumour following surgery to improve surveillance and endoscopic strategies. METHODS: The present study was based on patients who participated in the prospective preSANO trial with adenocarcinoma or squamous cell carcinoma of the oesophagus or oesophagogastric junction treated in four Dutch hospitals between 2013 and 2016...
December 2020: British Journal of Surgery