journal
https://read.qxmd.com/read/38634312/ethnic-density-and-first-episode-psychosis-in-the-british-pakistani-population-findings-from-the-east-lancashire-early-intervention-service
#1
JOURNAL ARTICLE
Robert Qi, Masood Qureshi, Nadeem Gire, Imran B Chaudhry, Victoria Vass, Jason C McIntyre, Kaylee Barlow, Richard P Bentall, Ross G White, Nusrat Husain
BACKGROUND: Elevated risk of psychosis for ethnic minority groups has generally been shown to be mitigated by high ethnic density. However, past survey studies examining UK Pakistani populations have shown an absence of protective ethnic density effects, which is not observed in other South Asian groups. AIMS: To assess the ethnic density effect at a local neighbourhood level, in the UK Pakistani population in East Lancashire. METHOD: Data was collected by the East Lancashire Early Intervention Service, identifying all cases of first episode psychosis (FEP) within their catchment area between 2012 and 2020...
April 18, 2024: British Journal of Psychiatry
https://read.qxmd.com/read/38629297/dissonance-in-the-face-of-alzheimer-s-disease-breakthroughs-clinician-and-lay-stakeholder-acceptance-concerns-and-willingness-to-pay-for-emerging-disease-modifying-therapies
#2
JOURNAL ARTICLE
Irina Kinchin, Sharon Walsh, Rachel Dinh, Margaret Kapuwa, Sean P Kennelly, Ann-Marie Miller, Ann Nolan, Sean O'Dowd, Laura O'Philbin, Suzanne Timmons, Iracema Leroi
BACKGROUND: Introducing new disease-modifying therapies (DMTs) for Alzheimer's disease demands a fundamental shift in diagnosis and care for most health systems around the world. Understanding the views of health professionals, potential patients, care partners and taxpayers is crucial for service planning and expectation management about these new therapies. AIMS: To investigate the public's and professionals' perspectives regarding (1) acceptability of new DMTs for Alzheimer's disease; (2) perceptions of risk/benefits; (3) the public's willingness to pay (WTP)...
April 17, 2024: British Journal of Psychiatry
https://read.qxmd.com/read/38602168/dosage-effects-of-psychodynamic-and-schema-therapy-in-people-with-comorbid-depression-and-personality-disorder-four-arm-pragmatic-randomised-controlled-trial
#3
JOURNAL ARTICLE
Marit Kool, Henricus Van, Arnoud Arntz, Anna Bartak, Jaap Peen, Linda Dil, Katinka de Boer, Jack Dekker
BACKGROUND: Higher intensity of psychotherapy might improve treatment outcome in depression, especially in those with comorbid personality disorder. AIMS: To compare the effects of 25 individual sessions (weekly) of two forms of psychotherapy - short-term psychoanalytic supportive psychotherapy (SPSP) and schema therapy - with the same treatments given for 50 sessions (twice weekly) in people with depression and personality disorder. Trial registration: NTR5941...
April 11, 2024: British Journal of Psychiatry
https://read.qxmd.com/read/38602159/impaired-topology-and-connectivity-of-grey-matter-structural-networks-in-major-depressive-disorder-evidence-from-a-multi-site-neuroimaging-data-set
#4
JOURNAL ARTICLE
Jing-Yi Long, Kun Qin, Nanfang Pan, Wen-Liang Fan, Yi Li
BACKGROUND: Major depressive disorder (MDD) has been increasingly understood as a disruption of brain connectome. Investigating grey matter structural networks with a large sample size can provide valuable insights into the structural basis of network-level neuropathological underpinnings of MDD. AIMS: Using a multisite MRI data-set including nearly 2000 individuals, this study aimed to identify robust topology and connectivity abnormalities of grey matter structural network linked to MDD and relevant clinical phenotypes...
April 11, 2024: British Journal of Psychiatry
https://read.qxmd.com/read/38584324/towards-precision-in-the-diagnostic-profiling-of-patients-leveraging-symptom-dynamics-as-a-clinical-characterisation-dimension-in-the-assessment-of-major-depressive-disorder
#5
JOURNAL ARTICLE
Omid V Ebrahimi, Denny Borsboom, Ria H A Hoekstra, Sacha Epskamp, Edoardo G Ostinelli, Jojanneke A Bastiaansen, Andrea Cipriani
BACKGROUND: International guidelines present overall symptom severity as the key dimension for clinical characterisation of major depressive disorder (MDD). However, differences may reside within severity levels related to how symptoms interact in an individual patient, called symptom dynamics. AIMS: To investigate these individual differences by estimating the proportion of patients that display differences in their symptom dynamics while sharing the same overall symptom severity...
April 8, 2024: British Journal of Psychiatry
https://read.qxmd.com/read/38584319/associations-between-multimorbidity-and-neuropathology-in-dementia-consideration-of-functional-cognitive-disorders-psychiatric-illness-and-dementia-mimics
#6
JOURNAL ARTICLE
Calum A Hamilton, Fiona E Matthews, Johannes Attems, Paul C Donaghy, Daniel Erskine, John-Paul Taylor, Alan J Thomas
BACKGROUND: Multimorbidity, the presence of two or more health conditions, has been identified as a possible risk factor for clinical dementia. It is unclear whether this is due to worsening brain health and underlying neuropathology, or other factors. In some cases, conditions may reflect the same disease process as dementia (e.g. Parkinson's disease, vascular disease), in others, conditions may reflect a prodromal stage of dementia (e.g. depression, anxiety and psychosis). AIMS: To assess whether multimorbidity in later life was associated with more severe dementia-related neuropathology at autopsy...
April 8, 2024: British Journal of Psychiatry
https://read.qxmd.com/read/38563223/the-potential-unintended-consequences-of-mental-health-act-reforms-in-england-and-wales-on-people-with-intellectual-disability-and-or-autism-commentary-mckinnon-et-al
#7
JOURNAL ARTICLE
Iain McKinnon, Patrick Keown
No abstract text is available yet for this article.
April 2, 2024: British Journal of Psychiatry
https://read.qxmd.com/read/38497099/neurocognitive-skills-and-vulnerability-for-psychosis-in-depression-and-across-the-psychotic-spectrum-findings-from-the-pronia-consortium-corrigendum
#8
JOURNAL ARTICLE
Carolina Bonivento, Lana Kambeitz-Ilankovic, Eleonora Maggioni, Stefan Borgwardt, Rebekka Lencer, Eva Meisenzahl, Joseph Kambeitz, Stephan Ruhrmann, Raimo K R Salokangas, Alessandro Bertolino, Alexandra Stainton, Julian Wenzel, Christos Pantelis, Stephen J Wood, Rachel Upthegrove, Nikolaos Koutsouleris, Paolo Brambilla
No abstract text is available yet for this article.
March 18, 2024: British Journal of Psychiatry
https://read.qxmd.com/read/38494743/the-effect-of-flexible-cognitive-behavioural-therapy-and-medical-treatment-including-antidepressants-on-post-traumatic-stress-disorder-and-depression-in-traumatised-refugees-pragmatic-randomised-controlled-clinical-trial-corrigendum
#9
JOURNAL ARTICLE
Caecilie Böck Buhmann, Merete Nordentoft, Morten Ekstroem, Jessica Carlsson, Erik Lykke Mortensen
No abstract text is available yet for this article.
March 18, 2024: British Journal of Psychiatry
https://read.qxmd.com/read/38433599/medical-assistance-in-dying-for-mental-illness-a-complex-intervention-requiring-a-correspondingly-complex-evaluation-approach
#10
REVIEW
Hamer Bastidas-Bilbao, David Castle, Mona Gupta, Vicky Stergiopoulos, Lisa D Hawke
Medical assistance in dying for mental illness as a sole underlying medical condition (MAiD MI-SUMC) is a controversial and complex policy in terms of psychosocial and ethical medical practice implications. We discuss the status of MAiD MI-SUMC in Canada and argue for the use of the UK Medical Research Council's framework on complex interventions in programme evaluations of MAiD MI-SUMC. It is imperative to carefully and rigorously evaluate the implementation of MAiD MI-SUMC to ensure an understanding of the multiple facets of implementation in contexts permeated by unique social, economic, cultural and historical influences, with a correspondingly diverse array of outcomes...
March 4, 2024: British Journal of Psychiatry
https://read.qxmd.com/read/38356396/the-usability-and-reliability-of-a-smartphone-application-for-monitoring-future-dementia-risk-in-ageing-uk-adults
#11
JOURNAL ARTICLE
Graham Reid, Philip Vassilev, Jessica Irving, Triin Ojakäär, Liron Jacobson, Erin G Lawrence, Jenny Barnett, Malika Tapparel, Ivan Koychev
BACKGROUND: The rising number of dementia diagnoses and imminent adoption of disease-modifying treatments necessitate innovative approaches to identify individuals at risk, monitor disease course and intervene non-pharmacologically earlier in the disease course. Digital assessments of dementia risk and cognitive function have the potential to outperform traditional in-person assessments in terms of their affordability, accuracy and longitudinal tracking abilities. However, their accessibility and reliability in older adults is unclear...
February 15, 2024: British Journal of Psychiatry
https://read.qxmd.com/read/38356355/protecting-and-promoting-editorial-independence
#12
JOURNAL ARTICLE
Kamaldeep Bhui, Aileen O'Brien, Rachel Upthegrove, Alexander C Tsai, Mustafa Soomro, Giles Newton-Howes, Matthew R Broome, Andrew Forrester, Patricia Casey, Anne M Doherty, William Lee, Kenneth R Kaufman
We argue that editorial independence, through robust practice of publication ethics and research integrity, promotes good science and prevents bad science. We elucidate the concept of research integrity, and then discuss the dimensions of editorial independence. Best practice guidelines exist, but compliance with these guidelines varies. Therefore, we make recommendations for protecting and strengthening editorial independence.
February 15, 2024: British Journal of Psychiatry
https://read.qxmd.com/read/38347829/borderline-intellectual-functioning-and-psychosis-adult-psychiatric-morbidity-survey-evidence-corrigendum
#13
JOURNAL ARTICLE
A Hassiotis, M Noor, P Bebbington, A Ali, J Wieland, T Qassem
No abstract text is available yet for this article.
February 13, 2024: British Journal of Psychiatry
https://read.qxmd.com/read/38344814/the-impact-of-reduced-routine-community-mental-healthcare-on-people-from-minority-ethnic-groups-during-the-covid-19-pandemic-qualitative-study-of-stakeholder-perspectives
#14
JOURNAL ARTICLE
Catherine Winsper, Rahul Bhattacharya, Kamaldeep Bhui, Graeme Currie, Dawn Edge, David Ellard, Donna Franklin, Paramjit Gill, Steve Gilbert, Noreen Khan, Robin Miller, Zahra Motala, Vanessa Pinfold, Harbinder Sandhu, Swaran P Singh, Scott Weich, Domenico Giacco
BACKGROUND: Enduring ethnic inequalities exist in mental healthcare. The COVID-19 pandemic has widened these. AIMS: To explore stakeholder perspectives on how the COVID-19 pandemic has increased ethnic inequalities in mental healthcare. METHOD: A qualitative interview study of four areas in England with 34 patients, 15 carers and 39 mental health professionals from National Health Service (NHS) and community organisations (July 2021 to July 2022)...
February 12, 2024: British Journal of Psychiatry
https://read.qxmd.com/read/38328972/association-of-cognitive-reserve-with-the-risk-of-dementia-in-the-uk-biobank-role-of-polygenic-factors
#15
JOURNAL ARTICLE
Wenzhe Yang, Jiao Wang, Abigail Dove, Michelle M Dunk, Xiuying Qi, David A Bennett, Weili Xu
BACKGROUND: It remains unclear whether cognitive reserve can attenuate dementia risk among people with different genetic predispositions. AIMS: We aimed to examine the association between cognitive reserve and dementia, and further to explore whether and to what extent cognitive reserve may modify the risk effect of genetic factors on dementia. METHOD: Within the UK Biobank, 210 631 dementia-free participants aged ≥60 years were followed to detect incident dementia...
February 8, 2024: British Journal of Psychiatry
https://read.qxmd.com/read/38328941/predictors-of-primary-care-psychological-therapy-outcomes-for-depression-and-anxiety-in-people-living-with-dementia-evidence-from-national-healthcare-records-in-england
#16
JOURNAL ARTICLE
Georgia Bell, Celine El Baou, Rob Saunders, Joshua E J Buckman, Georgina Charlesworth, Marcus Richards, Caroline Fearn, Barbara Brown, Shirley Nurock, Stuart Michael, Paul Ware, Natalie L Marchant, Elisa Aguirre, Miguel Rio, Claudia Cooper, Stephen Pilling, Amber John, Joshua Stott
BACKGROUND: Psychological therapies can be effective in reducing symptoms of depression and anxiety in people living with dementia (PLWD). However, factors associated with better therapy outcomes in PLWD are currently unknown. AIMS: To investigate whether dementia-specific and non-dementia-specific factors are associated with therapy outcomes in PLWD. METHOD: National linked healthcare records were used to identify 1522 PLWD who attended psychological therapy services across England...
February 8, 2024: British Journal of Psychiatry
https://read.qxmd.com/read/38270148/assessment-of-perinatal-anxiety-diagnostic-accuracy-of-five-measures
#17
JOURNAL ARTICLE
Susan Ayers, Rose Coates, Andrea Sinesi, Helen Cheyne, Margaret Maxwell, Catherine Best, Stacey McNicol, Louise R Williams, Nazihah Uddin, Una Hutton, Grace Howard, Judy Shakespeare, James J Walker, Fiona Alderdice, Julie Jomeen
BACKGROUND: Anxiety in pregnancy and after giving birth (the perinatal period) is highly prevalent but under-recognised. Robust methods of assessing perinatal anxiety are essential for services to identify and treat women appropriately. AIMS: To determine which assessment measures are most psychometrically robust and effective at identifying women with perinatal anxiety (primary objective) and depression (secondary objective). METHOD: We conducted a prospective longitudinal cohort study of 2243 women who completed five measures of anxiety and depression (Generalized Anxiety Disorder scale (GAD) two- and seven-item versions; Whooley questions; Clinical Outcomes in Routine Evaluation (CORE-10); and Stirling Antenatal Anxiety Scale (SAAS)) during pregnancy (15 weeks, 22 weeks and 31 weeks) and after birth (6 weeks)...
January 25, 2024: British Journal of Psychiatry
https://read.qxmd.com/read/38268114/what-impact-could-the-legalisation-of-recreational-cannabis-have-on-the-health-of-the-uk-lessons-from-the-rest-of-the-world
#18
JOURNAL ARTICLE
Emmert Roberts
Several jurisdictions across the globe have introduced legislation to legally permit the sale and consumption of recreational cannabis. This editorial considers current evidence from the rest of the world and asks how this might inform the possible consequences of 'legalisation' models in the UK.
January 25, 2024: British Journal of Psychiatry
https://read.qxmd.com/read/38470304/the-experience-of-felt-presence-in-a-general-population-sample
#19
JOURNAL ARTICLE
Sanne G Brederoo, Ben Alderson-Day, Janna N de Boer, Mascha M J Linszen, Iris E C Sommer
Felt presence is a widely occurring experience, but remains under-recognised in clinical and research practice. To contribute to a wider recognition of the phenomenon, we aimed to assess the presentation of felt presence in a large population sample ( n = 10 447) and explore its relation to key risk factors for psychosis. In our sample 1.6% reported experiencing felt presence in the past month. Felt presence was associated with visual and tactile hallucinations and delusion-like thinking; it was also associated with past occurrence of adverse events, loneliness and poor sleep...
April 2024: British Journal of Psychiatry
https://read.qxmd.com/read/38470303/mental-health-of-heterosexual-women-married-to-homosexual-men-a-major-but-neglected-issue
#20
JOURNAL ARTICLE
Azeem Kaleem
No abstract text is available yet for this article.
April 2024: British Journal of Psychiatry
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