journal
https://read.qxmd.com/read/37170922/efficacy-and-safety-of-dupilumab-in-patients-with-severe-chronic-hand-eczema-with-inadequate-response-or-intolerance-to-alitretinoin-a-randomized-double-blind-placebo-controlled-phase-iib-proof-of-concept-study
#21
JOURNAL ARTICLE
Angelique N Voorberg, Esmé Kamphuis, Wietske A Christoffers, Marie L A Schuttelaar
BACKGROUND: Effective treatment options for patients with chronic hand eczema (CHE) are scarce. Dupilumab is licensed for the treatment of moderate-to-severe atopic dermatitis and has shown promising results on hand eczema in other studies. OBJECTIVE: To evaluate the efficacy and safety of dupilumab in adult patients with severe CHE (subtypes recurrent vesicular HE or chronic fissured HE) with an inadequate response/intolerance to alitretinoin, or when alitretinoin is medically inadvisable...
May 12, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37167296/prediction-of-response-to-dupilumab-treatment
#22
EDITORIAL
DirkJan Hijnen, Jill Olydam
No abstract text is available yet for this article.
May 11, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37162019/do-saad-become-a-new-method-of-assessing-the-psychological-burden-of-alopecia-areata
#23
JOURNAL ARTICLE
Taisuke Ito, Reiko Kageyama
No abstract text is available yet for this article.
May 10, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37162007/incidence-and-prevalence-of-generalised-pustular-psoriasis-in-multi-ethnic-johor-bahru-malaysia-a-population-based-cohort-study-using-routinely-captured-electronic-health-records-in-teleprimary-care-tpc%C3%A2-clinical-information-system-from-2010-to-2020
#24
JOURNAL ARTICLE
Siew Eng Choon, Alison K Wright, Christopher E M Griffiths, Kit Wan Wong, Kwee Eng Tey, Yee Ting Lim, Keow Yin Chua, Darren M Ashcroft
BACKGROUND: There is limited understanding of the epidemiology of generalised pustular psoriasis (GPP) internationally, with no population-based estimates of GPP in Southeast Asia. OBJECTIVES: To determine the incidence and prevalence of GPP in the Malaysian population and characterise its flares and trigger factors. METHODS: A population-based cohort study using the Teleprimary Care database between January 2010 and December 2020. We identified 230 dermatologist-confirmed GPP cases by ICD-10 diagnostic codes...
May 10, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37155595/rethinking-caucasian-a-push-towards-more-equitable-language-in-dermatology
#25
JOURNAL ARTICLE
Jeanette R Comstock, Olushola L Akinshemoyin Vaughn, Idowu Olugbade, Beth A Drolet
No abstract text is available yet for this article.
May 8, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37155583/efficacity-and-safety-of-dupilumab-in-bullous-pemphigoid-a-retrospective-multicentric-study-of-36-patients
#26
JOURNAL ARTICLE
Parna Moghadam, Emmanuelle Tancrede, Jean-David Bouaziz, Julien Kallout, Christophe Bedane, Edouard Begon, Isabelle Bourgault-Villada, Andreea Calugareanu, Olivier Dereure, Fatma Jendoubi, Anne Pham-Ledard, Saskia Ingen-Housz-Oro, Catherine Picard-Dahan, Manuelle Viguier, Thibault Mahevas, Marie Jachiet, Estelle Charvet, Charles Cassius, Marina Alexandre, Clémence Lepelletier
No abstract text is available yet for this article.
May 8, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37151092/can-brepocitinib-be-formulated-into-an-effective-topical-therapy-to-treat-mild-to-moderate-chronic-plaque-psoriasis
#27
EDITORIAL
William C Cranwell, Rodney D Sinclair
No abstract text is available yet for this article.
May 8, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37146166/mpox-an-updated-review-of-dermatological-manifestations-in-the-current-outbreak
#28
JOURNAL ARTICLE
Carlo Alberto Maronese, Gianluca Avallone, Italo Francesco Aromolo, Cristina Beatrice Spigariolo, Eleonora Quattri, Stefano Ramoni, Carlo Giovanni Carrera, Angelo Valerio Marzano
Monkeypox (mpox) is a disease caused by a double-stranded DNA orthopoxvirus discovered in 1958. In 2022 an outbreak on an unprecedented scale marked its transition from neglected, zoonotic disease circulating almost exclusively within African borders to sexually transmitted infection (STI) of international concern. Although phylogenetic evidence suggests progressive evolution from the strain associated with the 2018 outbreak in Nigeria, epidemiological links with previous cases are still incompletely elucidated...
May 5, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37146163/from-the-genetic-characterization-to-new-potential-therapeutic-options-targeting-bcl-xl-in-merkel-carcinoma
#29
EDITORIAL
Thibault Kervarrec
No abstract text is available yet for this article.
May 5, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37146088/a-comparison-of-the-efficacy-of-skindex-16-and-skindex-29-in-dermatomyositis
#30
JOURNAL ARTICLE
Joshua Dan, Grant Sprow, Josef Concha, Jay Patel, Nilesh Kodali, DeAnna Diaz, Thomas Vazquez, Victoria P Werth
No abstract text is available yet for this article.
May 5, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37144735/validation-of-microrna-liquid-biopsy-for-diagnosis-and-risk-stratification-of-invasive-cutaneous-melanoma
#31
JOURNAL ARTICLE
Ryan Van Laar, Babak Latif, Sam King, Christopher Love, Nadine Taubenheim, Esha Kalanooriya, Wandi Wang, Mirette Saad, Ingrid Winship, Anthony Azzi, Alister Lilleyman, Tony Landgren
IMPORTANCE: Non-invasive molecular biomarkers are needed to improve the early, accurate and precise diagnosis of invasive cutaneous melanoma. OBJECTIVE: To independently validate a previously-identified circulating microRNA signature of melanoma (MEL38). Secondly, to develop of a complementary microRNA signature, optimized for prognostication. DESIGN, SETTING & PARTICIPANTS: MicroRNA expression profiling was performed on plasma samples from a multi-centre observational case-control study, involving patients with primary or metastatic melanoma, melanoma in-situ, non-melanoma skin cancer, or benign nevi...
May 5, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37143371/worst-area-local-hidradenitis-suppurativa-activity-and-severity-index-revised-w-hasi-r-a-study-evaluating-construct-validity
#32
JOURNAL ARTICLE
Gretchen Bellefeuille, Briana Paiewonsky, Bisma Khalid, Rebecca L Freese, Michelle A Lowes, Joslyn S Kirby, Afsaneh Alavi, Noah Goldfarb
No abstract text is available yet for this article.
May 5, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37140010/impact-of-house-dust-mite-in-vitiligo-skin-environmental-contribution-to-increased-cutaneous-immunity-and-melanocyte-detachment
#33
JOURNAL ARTICLE
Hanene Bzioueche, Katia Boniface, Claire Drullion, Sandrine Marchetti, Bérengère Chignon-Sicard, Laura Sormani, Stéphane Rocchi, Julien Senechal, Thierry Passeron, Meri K Tulic
BACKGROUND: Vitiligo is an autoimmune skin disorder characterized by loss of melanocytes. Protease-mediated disruption of junctions between keratinocytes and/or keratinocyte intrinsic dysfunction may directly contribute to melanocyte loss. House dust mite (HDM), an environmental allergen with potent protease activity, contributes to respiratory and gut disease but also to atopic dermatitis and rosacea. OBJECTIVE: To verify if HDM can contribute to melanocyte detachment in vitiligo and if so, by which mechanism(s)...
May 4, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37140007/immune-checkpoint-inhibitor-bullous-pemphigoid-is-characterized-by-interleukin-4-and-interleukin-13-expression-and-responds-to-dupilumab-treatment
#34
JOURNAL ARTICLE
William D Shipman, Katelyn Singh, Jeffrey M Cohen, Jonathan Leventhal, William Damsky, Mary M Tomayko
No abstract text is available yet for this article.
May 4, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37132498/does-the-understanding-of-signalling-pathways-pave-the-way-to-therapies-for-keratinisation-disorders
#35
EDITORIAL
Hans C Hennies
No abstract text is available yet for this article.
May 3, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37132472/covid-19-and-the-skin-three-years-on-long-term-impacts-emerging-trends-and-clinical-practice
#36
JOURNAL ARTICLE
Esther E Freeman, Ignacio Garcia-Doval, Luigi Naldi, Rod J Hay
No abstract text is available yet for this article.
May 3, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37132470/a-centre-based-ambulatory-care-concept-for-hidradenitis-suppurativa-improves-disease-activity-burden-and-patient-satisfaction-results-from-the-randomised-controlled-trial-esmail
#37
JOURNAL ARTICLE
Michael Schultheis, Petra Staubach, Georgios Nikolakis, Lukas Schollenberger, Melanie Mauch, Marion Burckhardt, Marcus Heise, Marina Zamsheva, Alexandra Strobel, Gero Langer, Falk Bechara, Uwe Kirschner, Katharina Hennig, Christian Kunte, Matthias Goebeler, Stephan Grabbe
BACKGROUND: Hidradenitis suppurativa is an inflammatory disease of the inverse skin regions that occurs particularly in young women and affects approximately 1% of the population. Outpatient care is often inadequate and usually cannot prevent progression. OBJECTIVE: The aim of the EsmAiL trial was to evaluate whether an innovative care concept can decrease disease activity and burden, as well as improve patient satisfaction. METHODS: EsmAiL was conducted as a two-arm, multicentre, prospective randomised controlled trial including 553 adults with HS...
May 3, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37132464/buried-dermal-interrupted-or-vertical-mattress-what-to-prefer-for-dermal-layer-suturing-of-surgical-skin-wounds
#38
JOURNAL ARTICLE
Suman Patra, Thoyiib Paramal Karat, Maninder Kaur
No abstract text is available yet for this article.
May 3, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37129990/correction-to-local-cutaneous-refractoriness-to-sun-exposure-following-omalizumab-injections-in-solar-urticaria
#39
(no author information available yet)
No abstract text is available yet for this article.
May 2, 2023: British Journal of Dermatology
https://read.qxmd.com/read/37120724/dupilumab-improves-patient-reported-symptoms-and-health-related-quality-of-life-in-children-aged-6-11-years-with-severe-atopic-dermatitis
#40
JOURNAL ARTICLE
Carsten Flohr, Alan D Irvine, Michael J Cork, Eric L Simpson, Andreas Wollenberg, Mette Deleuran, Amy Praestgaard, Ryan B Thomas, Ana B Rossi
No abstract text is available yet for this article.
April 30, 2023: British Journal of Dermatology
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