BJU International

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OBJECTIVES: to apply a new evidence-gathering methodology, called reverse systematic review (RSR), to analyze the influence of different continence classification criteria on urinary continence rates among open (RRP), laparoscopic (LRP) and robotic (RARP) radical prostatectomy. MATERIALS AND METHODS: a search was carried out in 8 databases between 2000 and 2020 through Systematic Reviews (SR) studies referring RRP, LRP or RARP (80 SR). All references used in these SR were captured referring to 910 papers in a global database called EVIDENCE...

OBJECTIVE: To evaluate the performance of risk calculators (RCs) predicting lymph node invasion (LNI) and extraprostatic extension (EPE) in men undergoing transperineal MRI/TRUS-fusion template saturation biopsy (TTSB) and conventional systematic transrectal TRUS-guided biopsy (SB). PATIENTS AND METHODS: RCs were tested in a consecutive cohort of 645 men undergoing radical prostatectomy with extended pelvic lymph node dissection between 2005 and 2019. TTSB was performed in 230 (35...

Prostate cancer is a major health concern in Sub-Saharan Africa (SSA), with high incidence and mortality rates. However, the widely used prostate-specific antigen (PSA) screening is not readily available or affordable in SSA. Alternative screening strategies, such as risk stratification approaches and cost-effective PSA tests, are being explored to target high-risk individuals and improve access to screening. Diagnosis of prostate cancer in SSA is challenging due to the lack of access to diagnostic tools and limited healthcare resources...

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BACKGROUND: China has a large population and complex geographical environment, which is lead to a large number of urolithiasis patients. However, there is a dearth of comprehensive investigations of urolithiasis prevalence. Consequently, This study aimed to estimate the pooled prevalence , as well as the spatial and temporal distribution, urolithiasis among subjects in China. METHODS AND MATERIALS: We conducted a comprehensive search of both Chinese and English databases to retrieve literature pertaining to the prevalence of urolithiasis in the indigenous Chinese population...

OBJECTIVES: To identify and explore barriers to, and enablers of active surveillance (AS) in men with low-risk prostate cancer (LRPC), as perceived by prostate cancer clinicians. SUBJECTS AND METHODS: Urologists and radiation oncologists in Australia and New Zealand were purposively sampled for a cross-section on gender and practice setting (metropolitan/regional; public/private). Using a grounded theory approach, semi-structed interviews were conducted with participants...

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No abstract text is available yet for this article.

OBJECTIVE: To compare the outcome and morbidity of B-TUEP and ThuLEP to HoLEP in treatment of large symptomatic benign prostatic obstruction (BPO) through non inferiority randomized controlled trial (NCT03916536). PATIENTS AND METHODS: 155 patients were recruited from a single center between February 2019 and August 2020. All had BPO with a prostate size > 80cc. The cases were randomly assigned to HoLEP, ThuLEP or B-TUEP using computer generated random tables in 1:1:1 ratio...

INTRODUCTION: Preoperative nuclear medicine renal scintigraphy (NMRS) is often used to predict estimated glomerular filtration (eGFR) after nephrectomy by estimating preoperative split renal function. We sought to determine whether a simple point-of-care measurement system estimating renal parenchymal volume using tools ubiquitously available could be used to replace NMRS in current clinical practice. MATERIALS/METHODS: We performed a retrospective review of patients who underwent abdominal cross-sectional imaging (CT/MRI) and mercaptoacetyltriglycine nuclear medicine renal scintigraphy (NMRS) prior to total nephrectomy at a single institution...

PURPOSE: Intrarenal pressure (IRP) is thought to play a role in complications following ureteroscopy. This area is poorly studied because of the difficulty in routinely measuring IRP. We report on our first-in-human experience using the LithoVue EliteTM ureteroscope (Boston Scientific). METHODS: A single-arm retrospective observational analysis was performed in 50 consecutive patients undergoing ureteroscopic lithotripsy using the LithoVue Elite™ system with pressure sensing capability between April 2022-February 2023 at two centres...

BACKGROUND: The demand for methodological rigour in preclinical studies is increasing since the research reproducibility and transparency in the medico-scientific field are being questioned. As a result, we investigated the prevalence and the trends of essential study design elements in preclinical urological studies, as well as key factors which may improve methodological rigour. METHODS AND RESULTS: PubMed was searched to include preclinical urological studies published between July 2007 to June 2021...

OBJECTIVE: To provide an update on the association between preoperative membranous urethral length (MUL) and postoperative urinary incontinence (UI) in men who undergo robot assisted radical prostatectomy (RARP) / robot assisted laparoscopic prostatectomy (RALP). MATERIALS: UI is common after RARP / RALP, and early recovery of continence is one of the most important functional outcomes following surgery. MUL has been identified as a factor associated with continence recovery following RARP / RALP...

OBJECTIVES: To evaluate the pressures range generated in the human renal collecting system during ureteroscopy, in a large patient sample, and to investigate a relationship between IRP and outcome. PATIENTS AND METHODS: A prospective multi-institutional study was conducted, with ethics board approval; February 2022-March 2023. Recruitment was of 120 consecutive consenting adult patients undergoing semi-rigid ureteroscopy and/or flexible ureterorenoscopy for urolithiasis or diagnostic purposes...

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OBJECTIVE: To assess whether a diagnostic pathway in which Prostate-specific membrane antigen (PSMA) positron-emission tomography (PET)/CT is used as single imaging modality is feasible to guide targeted biopsy and to detect clinically significant prostate cancer (csPCa) in biopsy-naïve men at high-risk of disease. PATIENTS AND METHODS: Sixty men with a prostate-specific antigen (PSA)-level of 20-50 ng/ml underwent 18 F-PSMA(DCFPyL)-PET/CT prior to prostate biopsies in this prospective, non-randomized cohort study...

No abstract text is available yet for this article.

No abstract text is available yet for this article.

OBJECTIVES: To compare the performance of currently available biopsy decision support tools incorporating magnetic resonance imaging (MRI) findings in predicting clinically significant prostate cancer (csPCa). PATIENTS AND METHODS: We retrospectively included men who underwent prostate MRI and subsequent targeted and/or systematic prostate biopsies in two large European centres. Available decision support tools were identified by a PubMed search. Performance was assessed by calibration, discrimination, decision curve analysis (DCA) and numbers of biopsies avoided vs...