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Archives of Disease in Childhood

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https://read.qxmd.com/read/31519552/vitamin-k-deficiency-bleeding-in-australian-infants-1993-2017-an-australian-paediatric-surveillance-unit-study
#1
Yvonne Zurynski, Cameron J Grover, Bin Jalaludin, Elizabeth J Elliott
OBJECTIVE: To undertake surveillance of vitamin K deficiency bleeding (VKDB) in Australia from 1993 to 2017, during a time of change to national recommendations and available vitamin K formulations. METHODS: Paediatricians reported cases of VKDB in infants aged <6 months and provided demographic, clinical and biochemical information via the Australian Paediatric Surveillance Unit. RESULTS: 58 cases were reported, of which 5 (9%) were early, 11 (19%) classic and 42 (72%) late VKDB...
September 13, 2019: Archives of Disease in Childhood
https://read.qxmd.com/read/31515202/developmental-delay-an-ambiguous-term-in-need-of-change
#2
Lisa Bernadette Grech
No abstract text is available yet for this article.
September 12, 2019: Archives of Disease in Childhood
https://read.qxmd.com/read/31506259/mind-the-gap-integrating-physical-and-mental-healthcare-for-children-with-functional-symptoms
#3
EDITORIAL
Isobel Heyman
No abstract text is available yet for this article.
September 10, 2019: Archives of Disease in Childhood
https://read.qxmd.com/read/31492660/child-death-review-statutory-and-operational-guidance-maximising-learning-from-child-deaths
#4
James Fraser, Vicky Sleap, Peter Sidebotham
No abstract text is available yet for this article.
September 6, 2019: Archives of Disease in Childhood
https://read.qxmd.com/read/31488402/nebulised-hypertonic-saline-in-moderate-to-severe-bronchiolitis-a-randomised-clinical-trial
#5
Raphaelle Jaquet-Pilloud, Marie-Elise Verga, Michel Russo, Mario Gehri, Jean-Yves Pauchard
OBJECTIVES: To investigate whether nebulised hypertonic saline (HS) treatment would decrease length of hospital stay (LOS) among infants with moderate-to severe-bronchiolitis compared with standard supportive care (SC). METHODS: We conducted an open, multicentre, randomised clinical trial from 1 April 2013 to 31 March 2016, in Swiss children's hospitals. Patients aged 6 weeks to 24 months with a primary diagnosis of moderate or severe bronchiolitis were included...
September 5, 2019: Archives of Disease in Childhood
https://read.qxmd.com/read/31488401/idiopathic-calcinosis-in-a-paediatric-patient
#6
Edoardo Marrani, Lisa Gamalero, Giovanni Beltrami, Chiara Caporalini, Gabriele Simonini, Rolando Cimaz, Teresa Giani
No abstract text is available yet for this article.
September 5, 2019: Archives of Disease in Childhood
https://read.qxmd.com/read/31484632/mortality-and-respiratory-support-in-x-linked-myotubular-myopathy-a-recensus-retrospective-analysis
#7
Robert J Graham, Francesco Muntoni, Imelda Hughes, Sabrina W Yum, Nancy L Kuntz, Michele L Yang, Barry J Byrne, Suyash Prasad, Rachel Alvarez, Casie A Genetti, Tmirah Haselkorn, Emma S James, Laurie B LaRusso, Mojtaba Noursalehi, Salvador Rico, Alan H Beggs
PURPOSE: Individuals with X-linked myotubular myopathy (XLMTM) who survive infancy require extensive supportive care, including ventilator assistance, wheelchairs and feeding tubes. Half die before 18 months of age. We explored respiratory support and associated mortality risk in RECENSUS, particularly among patients ≤5 years old who received respiratory support at birth; this subgroup closely matches patients in the ASPIRO trial of gene therapy for XLMTM. DESIGN: RECENSUS is an international, retrospective study of patients with XLMTM...
September 4, 2019: Archives of Disease in Childhood
https://read.qxmd.com/read/31481360/exome-sequencing-in-patients-with-antiepileptic-drug-exposure-and-complex-phenotypes
#8
Adam Jackson, Heather Ward, Rebecca Louise Bromley, Charulata Deshpande, Pradeep Vasudevan, Ingrid Scurr, John Dean, Nora Shannon, Jonathon Berg, Susan Holder, Diana Baralle, Jill Clayton-Smith
INTRODUCTION: Fetal anticonvulsant syndrome (FACS) describes the pattern of physical and developmental problems seen in those children exposed to certain antiepileptic drugs (AEDs) in utero. The diagnosis of FACS is a clinical one and so excluding alternative diagnoses such as genetic disorders is essential. METHODS: We reviewed the pathogenicity of reported variants identified on exome sequencing in the Deciphering Developmental Disorders (DDD) Study in 42 children exposed to AEDs in utero, but where a diagnosis other than FACS was suspected...
September 3, 2019: Archives of Disease in Childhood
https://read.qxmd.com/read/31473602/use-of-ct-in-children-with-minor-head-injuries-with-isolated-vomiting
#9
Helen Newsome
No abstract text is available yet for this article.
August 31, 2019: Archives of Disease in Childhood
https://read.qxmd.com/read/31473601/use-of-oral-corticosteroids-in-the-treatment-of-alopecia-areata
#10
Ben Jie Cowley, Jiawen Dong
No abstract text is available yet for this article.
August 31, 2019: Archives of Disease in Childhood
https://read.qxmd.com/read/31471281/evaluation-of-the-causal-effects-between-dopamine-infusion-changeover-and-fluctuations-in-mean-arterial-pressure-in-neonates
#11
Katherine Kirupakaran, Paula de Sousa, Celine Le Roux, Lauren Redwood, Heike Rabe
OBJECTIVE: To evaluate whether changing dopamine infusions every 12 hours and preparing these infusions 30 min before administration reduces blood pressure fluctuations in preterm and term neonates. DESIGN: This was a retrospective study using data from live patients on the neonatal unit and prospective study exploring stability of infusions in a laboratory-based neonatal ward simulation. SETTING: Single-centre study in a tertiary neonatal surgical unit in a university teaching hospital...
August 30, 2019: Archives of Disease in Childhood
https://read.qxmd.com/read/31466994/recommended-technology-to-relieve-oral-mucositis-not-yet-available-for-children-or-young-people-in-england-or-wales
#12
LETTER
Melody Redman, Katherine Harris, Jessica Elizabeth Morgan, Robert Phillips
No abstract text is available yet for this article.
August 29, 2019: Archives of Disease in Childhood
https://read.qxmd.com/read/31466993/developments-in-clinical-enteral-nutrition-fragments-from-the-archives
#13
Harriet Barraclough, John W Puntis
No abstract text is available yet for this article.
August 29, 2019: Archives of Disease in Childhood
https://read.qxmd.com/read/31466992/making-use-of-the-archives-archive
#14
EDITORIAL
Robert Scott-Jupp, Nick Brown
No abstract text is available yet for this article.
August 29, 2019: Archives of Disease in Childhood
https://read.qxmd.com/read/31466991/timing-of-voiding-cystourethrography-after-febrile-urinary-tract-infection-in-children-a-systematic-review
#15
REVIEW
Sara Mazzi, Katharina Rohner, Wesley Hayes, Marcus Weitz
BACKGROUND: Despite a trend towards early voiding cystourethrography (VCUG) after febrile urinary tract infection (fUTI) in children, clinical guidelines do not comment on the optimal timing and current practice varies considerably. OBJECTIVE: To assess whether the detection rate of vesicoureteric reflux (VUR) in children depends on the time period of VCUG procedure after onset of antibiotic therapy. METHODS: MEDLINE, EMBASE and Cochrane Controlled Trials Register electronic databases were searched for eligible studies without language or time restriction (19 November 2018)...
August 29, 2019: Archives of Disease in Childhood
https://read.qxmd.com/read/31462437/enterovirus-parechovirus-adenovirus-and-herpes-virus-type-6-viraemia-in-fever-without-source
#16
Arnaud Gregoire L'Huillier, Chiara Mardegan, Samuel Cordey, Fanny Luterbacher, Sebastien Papis, Florence Hugon, Laurent Kaiser, Alain Gervaix, Klara Posfay-Barbe, Annick Galetto-Lacour
OBJECTIVES: To evaluate the potential associations between fever without a source (FWS) in children and detection of human enterovirus (HEV), human parechovirus (HPeV), adenovirus (AdV) and human herpesvirus type 6 (HHV-6) in the plasma; and to assess whether the detection of viruses in the plasma is associated with a reduced risk of serious bacterial infection (SBI) and antibiotic use. DESIGN AND SETTING: Between November 2015 and December 2017, this prospective, single-centre, diagnostic study tested the plasma of children <3 years old with FWS...
August 28, 2019: Archives of Disease in Childhood
https://read.qxmd.com/read/31462436/frequency-of-urinary-tract-infection-in-children-with-antenatal-diagnosis-of-urinary-tract-dilatation
#17
Marco Pennesi, Stefano Amoroso, Giulia Bassanese, Stefano Pintaldi, Giulia Giacomini, Egidio Barbi
BACKGROUND: Neonates with congenital urinary tract dilatation (UTD) may have an increased risk of urinary tract infections (UTI). At present, the management of these patients is controversial and the utility of continuous antibiotic prophylaxis (CAP) remains uncertain as the literature presents contradicting evidence. The aim of this observational study was to assess UTI occurrence in children with prenatal diagnosis of urinary collecting system dilatation without antibiotic prophylaxis...
August 28, 2019: Archives of Disease in Childhood
https://read.qxmd.com/read/31462435/united-nations-convention-on-the-rights-of-the-child-in-acute-paediatrics
#18
Colin Powell
No abstract text is available yet for this article.
August 28, 2019: Archives of Disease in Childhood
https://read.qxmd.com/read/31462434/bone-and-joint-infections-in-oxford-a-10-year-retrospective-review
#19
LETTER
Movin Abeywickrema, Xinxue Liu, Dominic F Kelly, Tim Theologis, Andrew J Pollard, Seilesh Kadambari
No abstract text is available yet for this article.
August 28, 2019: Archives of Disease in Childhood
https://read.qxmd.com/read/31462433/oxygen-saturation-thresholds-in-bronchiolitis-examining-admissions
#20
Tim J van Hasselt, Bhavna Singham, Eve Bassett, Ian D Wacogne
OBJECTIVE: Examine admissions for bronchiolitis, comparing centres with oxygen saturation thresholds for admission of 90% versus 92%. DESIGN: Prospective multi-centre service evaluation, all admissions for bronchiolitis during 4-week period, November 2018. SETTING: Paediatric departments across 12 hospitals in the West Midlands, UK. PATIENTS: 320 patients aged 6 weeks-1 year, diagnosis of bronchiolitis, exclusions: chronic illness or high dependency/intensive care admission...
August 28, 2019: Archives of Disease in Childhood
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