Annals of Surgery

Nicolas A Brozzi, Matthias Loebe, Fouad Ghazi Souki, Thiago Beduschi, Ali Ghodzisad, Akin Tekin, Astrid Nicolau-Raducu, Rodrigo M Vianna
INTRODUCTION: Complexity of combined heart-liver transplantation has resulted in low adoption rates. We report a case series of adult patients receiving en-bloc heart-liver transplantation (HLTx), describe technical aspects, and discuss benefits of the technique. METHODS: Retrospective review of patients receiving en-bloc HLTx over 18 months, with clinical follow up to 1 year. Primary outcomes included postoperative mortality and major complications. Secondary outcomes included 1-year survival, cardiac or hepatic allograft rejection, and infection...
January 14, 2020: Annals of Surgery
Mary Shen, Joceline V Vu, Michael J Englesbe
No abstract text is available yet for this article.
January 6, 2020: Annals of Surgery
Yuming Jiang, Cheng Jin, Heng Yu, Jia Wu, Chuanli Chen, Qingyu Yuan, Weicai Huang, Yanfeng Hu, Yikai Xu, Zhiwei Zhou, George A Fisher, Guoxin Li, Ruijiang Li
OBJECTIVE: We aimed to develop a deep learning-based signature to predict prognosis and benefit from adjuvant chemotherapy using preoperative computed tomography (CT) images. BACKGROUND: Current staging methods do not accurately predict the risk of disease relapse for patients with gastric cancer. METHODS: We proposed a novel deep neural network (S-net) to construct a CT signature for predicting disease-free survival (DFS) and overall survival in a training cohort of 457 patients, and independently tested it in an external validation cohort of 1158 patients...
January 6, 2020: Annals of Surgery
Sheraz Markar, Giola Santoni, John Maret-Ouda, Miia Artama, Martti Färkkilä, Elsebeth Lynge, Eero Pukkala, Eivind Ness-Jensen, My von Euler-Chelpin, Jesper Lagergren
OBJECTIVE: To test the hypothesis that higher hospital volume decreases endoscopic and surgical re-intervention rates after antireflux surgery. BACKGROUND: Antireflux surgery for gastro-esophageal reflux disease is followed by varying rates of re-interventions. Whether hospital volume influences re-intervention rates is uncertain. METHODS: This population-based cohort study used nationwide data from Denmark, Finland, and Sweden for patients having undergone primary antireflux surgery...
January 6, 2020: Annals of Surgery
Luis Sabater, Javier Padillo
No abstract text is available yet for this article.
January 6, 2020: Annals of Surgery
Omeed Moaven, Clancy J Clark, Gregory B Russell, Konstantinos I Votanopoulos, Russell Howerton, Edward A Levine, Perry Shen
OBJECTIVE: To identify the survival benefit of different adjuvant approaches and factors influencing their efficacy after upfront resection of pancreatic ductal adenocarcinoma (PDAC). SUMMARY BACKGROUND DATA: The optimal adjuvant approach for PDAC remains controversial. METHODS: Patients from the National Cancer Database who underwent upfront PDAC resection from 2010 to 2014 were analyzed to determine clinical outcomes of different adjuvant treatment approaches, stratified according to pathologic characteristics...
January 6, 2020: Annals of Surgery
Alexey Kamenskiy, Paul Aylward, Anastasia Desyatova, Matthew DeVries, Christopher Wichman, Jason MacTaggart
BACKGROUND: Aortic elasticity creates a cushion that protects the heart from pressure injury, and a recoil that helps perfuse the coronary arteries. TEVAR has become first-line therapy for many aortic pathologies including trauma, but stent-grafts stiffen the aorta and likely increase LV afterload. OBJECTIVE: Test the hypothesis that trauma TEVAR is associated with LV mass increase and adverse off-target aortic remodeling. METHODS: Computed Tomography Angiography (CTA) scans of 20 trauma TEVAR patients (17 M/3 F) at baseline [age 34...
January 3, 2020: Annals of Surgery
Marcel Autran Machado, Marcel C Machado
No abstract text is available yet for this article.
January 3, 2020: Annals of Surgery
Jared M Wohlgemut, George Ramsay, Dwayne Boyers, Jan O Jansen
OBJECTIVE: To calculate the current and projected financial burden of EGS hospital admissions in a single-payer healthcare system. SUMMARY OF BACKGROUND DATA: EGS is an important acute care service, which demands significant healthcare resources. EGS admissions and associated costs have increased over time, associated with an aging demographic. The National Health Service is the sole provider of emergency care in Scotland. METHODS: Principal, high and low Scottish population projections were obtained for 2016 until 2041...
January 3, 2020: Annals of Surgery
David M Shahian
No abstract text is available yet for this article.
December 31, 2019: Annals of Surgery
Abeed H Chowdhury, Alfred Adiamah, Anisa Kushairi, Dileep N Lobo
No abstract text is available yet for this article.
December 31, 2019: Annals of Surgery
Silvio Nadalin, Ivan Capobianco
No abstract text is available yet for this article.
December 31, 2019: Annals of Surgery
Xiang-Dong Wu, Di Wu, Yong Liu, Wei Huang
No abstract text is available yet for this article.
December 31, 2019: Annals of Surgery
Giampaolo Perri, Laura Prakash, Wei Qiao, Gauri R Varadhachary, Robert Wolff, David Fogelman, Michael Overman, Shubham Pant, Milind Javle, Eugene J Koay, Joseph Herman, Michael Kim, Naruhiko Ikoma, Ching-Wei Tzeng, Jeffrey E Lee, Matthew H G Katz
OBJECTIVE: We sought to determine whether postoperative chemotherapy after preoperative therapy and pancreatectomy for pancreatic ductal adenocarcinoma (PDAC) prolongs survival. BACKGROUND: Data to support administering postoperative chemotherapy to patients who received preoperative therapy are lacking. METHODS: All patients with PDAC who underwent pancreatectomy after preoperative therapy between 2010 and July 2017 at The University of Texas MD Anderson Cancer Center were identified...
December 31, 2019: Annals of Surgery
Ian E Brown
No abstract text is available yet for this article.
December 27, 2019: Annals of Surgery
Osama Moussa, Maddalena Ardissino, Alice Tang, Laura Lazzari, Ophelia Millar, Paul Ziprin, Ara Darzi, Omar Khan, Peter Collins, Sanjay Purkayastha
OBJECTIVE: The aim of this study is to evaluate the effect of bariatric surgery on long-term risk of VTEs in a large cohort of patients with obesity. BACKGROUND: Obesity is a well-established risk factor for VTEs, such as pulmonary embolism and deep vein thrombosis. The rising prevalence of obesity and its associated co-morbidities, including VTE, represent a growing public health issue. METHODS: A nested, retrospective matched cohort study was designed and conducted on prospectively collected national electronic healthcare records data from the Clinical Practice Research Datalink...
December 17, 2019: Annals of Surgery
Xuefeng Leng, Wenwu He, Hong Yang, Yuping Chen, Chengchu Zhu, Wentao Fang, Zhentao Yu, Weimin Mao, Jiaqing Xiang, Zhijian Chen, Haihua Yang, Jiaming Wang, Qingsong Pang, Xiao Zheng, Hui Liu, Huanjun Yang, Tao Li, Xu Zhang, Qun Li, Geng Wang, Teng Mao, Xufeng Guo, Ting Lin, Mengzhong Liu, Jianhua Fu, Yongtao Han
OBJECTIVE: To determine the prognostic impact of pathologic lymph node (LN) status and investigate risk factors of recurrence in esophageal squamous cell carcinoma (ESCC) patients with pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (NCRT). SUMMARY BACKGROUND DATA: There are no large-scale prospective study data regarding ypN status and recurrence after pCR in ESCC patients receiving NCRT. METHODS: The NEOCRTEC5010 trial was a prospective multicenter trial that compared the survival and safety of NCRT plus surgery (S) with S in patients with locally advanced ESCC...
December 17, 2019: Annals of Surgery
Suk Kyun Hong, Sunho Choe, Nam-Joon Yi, Aesun Shin, Eun Kyung Choe, Kyung Chul Yoon, Kwang-Woong Lee, Kyung-Suk Suh
OBJECTIVE: To evaluate the long-term mortality of Korean live liver donors using data from a national donor registry by comparing it with the mortality of the general population. SUMMARY OF BACKGROUND DATA: Although live liver donors generally have a healthy status, their long-term mortality has not been properly addressed in a large donor registry. METHODS: Data of 10,116 live liver donors were drawn from a mandated national registry of Korean live liver donors between 2000 and 2015...
December 16, 2019: Annals of Surgery
Siva Raja, Thomas W Rice, Sudish C Murthy, Usman Ahmad, Marie E Semple, Eugene H Blackstone, Hemant Ishwaran
OBJECTIVE: The aim of this study was to assess the effect on survival of extent of lymphadenectomy during esophagectomy for patients undergoing multimodality (neoadjuvant) therapy for adenocarcinoma of the esophagus and esophagogastric junction using Worldwide Esophageal Cancer Collaboration data. SUMMARY BACKGROUND DATA: Previous worldwide data demonstrated that optimum lymphadenectomy during esophagectomy alone for esophageal cancer provides accurate staging and maximum survival...
December 16, 2019: Annals of Surgery
Giuseppe Malleo, Laura Maggino, Carlos Fernandez-Del Castillo, Roberto Salvia
No abstract text is available yet for this article.
December 16, 2019: Annals of Surgery
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