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Annals of Surgery

Elisa Bannone, Stefano Andrianello, Giovanni Marchegiani, Claudio Bassi
No abstract text is available yet for this article.
March 8, 2019: Annals of Surgery
Maura E Sullivan, Yoon Soo Park, Kathy Liscum, Ajit K Sachdeva, Patrice Gabler Blair, Melissa Gesbeck, Georges Bordage
OBJECTIVE: To assess the readiness of entering residents for clinical responsibilities, the American College of Surgeons (ACS) Division of Education developed the "Entering Resident Readiness Assessment" (ACS-ERRA) Program. SUMMARY BACKGROUND: ACS-ERRA is an online formative assessment that uses a key features approach to measure clinical decision-making skills and focuses on cases encountered at the beginning of residency. Results can be used to develop learning plans to address areas that may need reinforcement...
March 8, 2019: Annals of Surgery
Joseph DiNorcia, Sander S Florman, Brandy Haydel, Parissa Tabrizian, Richard M Ruiz, Goran B Klintmalm, Srinath Senguttuvan, David D Lee, C Burcin Taner, Elizabeth C Verna, Karim J Halazun, Maarouf Hoteit, Matthew H Levine, William C Chapman, Neeta Vachharajani, Federico Aucejo, Mindie H Nguyen, Marc L Melcher, Amit D Tevar, Abhinav Humar, Constance Mobley, Mark Ghobrial, Trevor L Nydam, Beth Amundsen, James F Markmann, Jennifer Berumen, Alan W Hemming, Alan N Langnas, Carol A Carney, Debra L Sudan, Johnny C Hong, Joohyun Kim, Michael A Zimmerman, Abbas Rana, Michael L Kueht, Christopher M Jones, Thomas M Fishbein, Daniela Markovic, Ronald W Busuttil, Vatche G Agopian
MINI: In a large, multicenter study of patients undergoing liver transplantation for hepatocellular carcinoma, complete pathologic response (cPR) to pretransplant locoregional therapy (LRT) portended significantly superior overall and recurrence-free survival. Multivariable predictors of cPR included age, sex, liver disease diagnosis, MELD, AFP, NLR, radiographic Milan status, and number of LRT treatments. OBJECTIVE: The aim of the study was to determine the rate, predictors, and impact of complete pathologic response (cPR) to pretransplant locoregional therapy (LRT) in a large, multicenter cohort of hepatocellular carcinoma (HCC) patients undergoing liver transplantation (LT)...
March 5, 2019: Annals of Surgery
Michael S Hu, Zeshaan N Maan, Tripp Leavitt, Wan Xing Hong, Robert C Rennert, Clement D Marshall, Mimi R Borrelli, Ted N Zhu, Mikaela Esquivel, Andrew Zimmermann, Adrian McArdle, Michael T Chung, Deshka S Foster, Ruth Ellen Jones, Geoffrey C Gurtner, Amato J Giaccia, H Peter Lorenz, Irving L Weissman, Michael T Longaker
OBJECTIVE: The aim of this study was to determine the interaction of full thickness excisional wounds and tumors in vivo. SUMMARY OF BACKGROUND DATA: Tumors have been described as wounds that do not heal due to similarities in stromal composition. On the basis of observations of slowed tumor growth after ulceration, we hypothesized that full thickness excisional wounds would inhibit tumor progression in vivo. METHODS: To determine the interaction of tumors and wounds, we developed a tumor xenograft/allograft (human head and neck squamous cell carcinoma SAS/mouse breast carcinoma 4T1) wound mouse model...
February 27, 2019: Annals of Surgery
Dimitri Dorcaratto, Guido Mazzinari, Maricarmen Fernandez, Elena Muñoz, Marina Garcés-Albir, Joaquin Ortega, Luis Sabater
MINI: Systematic review and meta-analysis on the effect of postoperative complications on oncologic results after colorectal cancer liver metastasis resection. The results based on data from 41 studies (12,817 patients) evidence the increased risk of mortality and recurrence for patients experiencing postresection complications. OBJECTIVE: To study the effect of postoperative complications (POC) on overall survival (OS) and disease-free survival (DFS) after surgical resection of colorectal liver metastases (CRLM)...
February 27, 2019: Annals of Surgery
Anthony J Hesketh, Aurora D Pryor
No abstract text is available yet for this article.
February 27, 2019: Annals of Surgery
Steven M Strasberg
No abstract text is available yet for this article.
February 27, 2019: Annals of Surgery
Patricia Sánchez-Velázquez, Xavier Muller, Giuseppe Malleo, Joon-Seong Park, Ho-Kyoung Hwang, Niccolò Napoli, Ammar A Javed, Yosuke Inoue, Nassiba Beghdadi, Marit Kalisvaart, Emanuel Vigia, Carrie D Walsh, Brendan Lovasik, Juli Busquets, Chiara Scandavini, Fabien Robin, Hideyuki Yoshitomi, Tara M Mackay, Olivier R Busch, Hermien Hartog, Stefan Heinrich, Ana Gleisner, Julie Perinel, Michael Passeri, Nuria Lluis, Dimitri A Raptis, Christoph Tschuor, Christian E Oberkofler, Michelle L DeOliveira, Henrik Petrowsky, John Martinie, Horacio Asbun, Mustapha Adham, Richard Schulick, Hauke Lang, Bas Groot Koerkamp, Marc G Besselink, Ho-Seong Han, Masaru Miyazaki, Cristina R Ferrone, Carlos Fernández-Del Castillo, Keith D Lillemoe, Laurent Sulpice, Karim Boudjema, Marco Del Chiaro, Joan Fabregat, David A Kooby, Peter Allen, Harish Lavu, Charles J Yeo, Eduardo Barroso, Keith Roberts, Paolo Muiesan, Alain Sauvanet, Akio Saiura, Christopher L Wolfgang, John L Cameron, Ugo Boggi, Dong-Sup Yoon, Claudio Bassi, Milo A Puhan, Pierre-Alain Clavien
OBJECTIVE: To use the concept of benchmarking to establish robust and standardized outcome references after pancreatico-duodenectomy (PD). BACKGROUND: Best achievable results after PD are unknown. Consequently, outcome comparisons among different cohorts, centers or with novel surgical techniques remain speculative. METHODS: This multicenter study analyzes consecutive patients (2012-2015) undergoing PD in 23 international expert centers in pancreas surgery...
February 27, 2019: Annals of Surgery
Alfred Adiamah, Pavel Skořepa, Arved Weimann, Dileep N Lobo
MINI: This meta-analysis of 16 randomized controlled trials reporting on 1387 patients has shown that preoperative immune-enhancing nutrition significantly reduces infectious complications, but not noninfectious complications, in patients undergoing surgery for gastrointestinal cancer.This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons...
February 26, 2019: Annals of Surgery
Sivesh K Kamarajah, Christopher J Sonnenday, Clifford S Cho, Timothy L Frankel, Filip Bednar, Theodore S Lawrence, Hari Nathan
INTRODUCTION: There is conflicting evidence for the benefit of adjuvant radiotherapy (RT) after resection of pancreatic ductal adenocarcinoma (PDAC), especially for margin-negative (R0) resections. We aimed to evaluate the association of adjuvant RT with survival after R0 resection of PDAC. METHODS: Using National Cancer Database (NCDB) data from 2004 to 2013, we identified patients with R0 resection of nonmetastatic PDAC. Patients with neoadjuvant radiotherapy and chemotherapy and survival <6 months were excluded...
February 25, 2019: Annals of Surgery
Eivind Gottlieb-Vedi, Joonas H Kauppila, George Malietzis, Magnus Nilsson, Sheraz R Markar, Jesper Lagergren
OBJECTIVE: Evaluate the existing literature comparing long-term survival after minimally invasive esophagectomy (MIE) and open esophagectomy (OE), and conduct a meta-analysis based on relevant studies. BACKGROUND: It is unknown whether the choice between MIE and OE influences the long-term survival in esophageal cancer. METHODS: A systematic electronic search for articles was performed in Medline, Embase, Web of Science, and Cochrane Library for studies comparing long-term survival after MIE and OE...
February 21, 2019: Annals of Surgery
James J Jung, Steven Yule, Sylvain Boet, Peter Szasz, Pansy Schulthess, Teodor Grantcharov
OBJECTIVE: To validate the Non-Technical Skills for Surgeons (NOTSS) system for assessment of the collective surgical teams' nontechnical skills after observing recordings of actual OR environment. BACKGROUND: The NOTSS system is a widely accepted tool to measure nontechnical skills of individual surgeons, and has mostly been used in the simulated setting. Surgical procedures are rarely performed by a single surgeon, but by a surgical team of attending surgeons, surgical assistants, and surgical trainees...
February 21, 2019: Annals of Surgery
Frédérique M U Mol, Robbert C Maatman, Luuke E G H De Joode, Percy Van Eerten, Marc R Scheltinga, Rudi Roumen
OBJECTIVE: The aim of this study was to discuss patient history and subjective findings at physical examination in a large case series to validate a proposed comprehensive set of major and minor diagnostic criteria. SUMMARY BACKGROUND DATA: Chronic abdominal pain in some patients is caused by the anterior cutaneous nerve entrapment syndrome (ACNES). ACNES is a clinical diagnosis as no functional testing or imaging modalities are available up to date. METHODS: This study retrospectively analyzed prospectively obtained data from consecutive patients who received the diagnosis ACNES during evaluation at the SolviMáx Center of Excellence for Abdominal Wall and Groin Pain, Eindhoven, The Netherlands, between June 1, 2011 and September 1, 2016...
February 20, 2019: Annals of Surgery
Simon S Evers, Alfor G Lewis, Cindy Tong, Yikai Shao, Rafael Alvarez, Elika Ridelman, Bethany Grant, Randy J Seeley
MINI: The data shows that surgery-induced gastric volume reduction by excision, plication, or contraction of gastric tissue is related to increased gastric emptying rate and increased GLP-1 response. However, unlike others suggested, increased GLP-1 responses are not related to improved glucose tolerance. The data reveals that a threshold of >75% reduction of gastric volume is necessary to induce long-term sustained weight loss with accompanied improvements of glucose tolerance. This most likely requires excising gastric tissue...
February 20, 2019: Annals of Surgery
Sepideh Gholami, Nancy E Kemeny, Taryn M Boucher, Mithat Gönen, Andrea Cercek, T Peter Kingham, Vinod Balachandran, Peter Allen, Ronald DeMatteo, Jeffrey Drebin, William Jarnagin, Michael D'Angelica
MINI: Patients with colorectal liver metastases and available KRAS data treated with resection and with or without adjuvant hepatic artery infusion chemotherapy were retrospectively evaluated. Adjuvant hepatic artery infusion was independently associated with improved outcomes regardless of KRAS mutational status. Adjuvant hepatic artery infusion may mitigate the worse outcomes seen in patients with resectable KRAS-MUT CRLM. OBJECTIVE: To investigate the impact of adjuvant hepatic artery infusion (HAI) in relation to KRAS mutational status in patients with resected colorectal cancer liver metastases (CRLM)...
February 19, 2019: Annals of Surgery
Yoshinaga Okugawa, Yuji Toiyama, Akira Yamamoto, Tsunehiko Shigemori, Shozo Ide, Takahito Kitajima, Hiroyuki Fujikawa, Hiromi Yasuda, Junichiro Hiro, Shigeyuki Yoshiyama, Takeshi Yokoe, Susumu Saigusa, Koji Tanaka, Yumiko Shirai, Minako Kobayashi, Masaki Ohi, Toshimitsu Araki, Donald C McMillan, Chikao Miki, Ajay Goel, Masato Kusunoki
MINI: In the present study, we systemically and comprehensively evaluated the prognostic significance of a combination of inflammatory factors using preoperative blood examination, and focused on the potential feasibility of our newly developed lymphocyte-CRP ratio (LCR) as a prognostic biomarker in CRC patients. We have firstly identified that a combination of lymphocytic counts along with CRP levels, which we defined as LCR, is a more reliable indicator of poor prognosis compared with other combinations of inflammatory markers, in CRC patients...
February 16, 2019: Annals of Surgery
David A Etzioni, Cynthia Lessow, Liliana G Bordeianou, Hiroko Kunitake, Sarah E Deery, Evie Carchman, Christina M Papageorge, George Fuhrman, Rachel V Seiler, James Ogilvie, Elizabeth B Habermann, Yu-Hui H Chang, Samuel R Money
MINI: We compared administrative data and National Surgical Quality Improvement Program data regarding the presence of 12 patient-level comorbidities. The level of disagreement between these data sources raises concerns regarding their ability to generate an accurate/unbiased estimate of patient-level risk. OBJECTIVE: To characterize agreement between administrative and registry data in the determination of patient-level comorbidities. BACKGROUND: Previous research finds poor agreement between these 2 types of data in the determination of outcomes...
February 16, 2019: Annals of Surgery
Adam Attaar, James D Luketich, Matthew J Schuchert, Daniel G Winger, Inderpal S Sarkaria, Katie S Nason
OBJECTIVE: The aim of the study was to determine whether prolonged air leak (PAL) is associated with postoperative morbidity and mortality following pulmonary resection after adjusting for differences in baseline characteristics using propensity score analysis. SUMMARY BACKGROUND DATA: Patients with PAL after lung resection have worse outcomes than those without PAL. However, adverse postoperative outcomes may also be secondary to baseline risk factors, such as poor lung function...
February 15, 2019: Annals of Surgery
Timothy H Mungroop, Sjors Klompmaker, Ulrich F Wellner, Ewout W Steyerberg, Andrea Coratti, Mathieu D'Hondt, Matteo de Pastena, Safi Dokmak, Igor Khatov, Olivier Saint-Marc, Uwe Wittel, Mohammed Abu Hilal, David Fuks, Ignasi Poves, Tobias Keck, Ugo Boggi, Marc G Besselink
MINI: Minimally invasive pancreatoduodenectomy (MIPD) may be associated with an increased risk of postoperative pancreatic fistula. In this study, the alternative Fistula Risk Score (a-FRS) was validated in a pan-European cohort of 952 patients undergoing MIPD and performed well after minor adjustment, in both open and MIPD. OBJECTIVE: The aim of the study was to validate and optimize the alternative Fistula Risk Score (a-FRS) for patients undergoing minimally invasive pancreatoduodenectomy (MIPD) in a large pan-European cohort...
February 13, 2019: Annals of Surgery
Hyuk-Joon Lee, Woo Jin Hyung, Han-Kwang Yang, Sang Uk Han, Young-Kyu Park, Ji Yeong An, Wook Kim, Hyoung-Il Kim, Hyung-Ho Kim, Seung Wan Ryu, Hoon Hur, Seong-Ho Kong, Gyu Seok Cho, Jin-Jo Kim, Do Joong Park, Keun Won Ryu, Young Woo Kim, Jong Won Kim, Joo-Ho Lee, Min-Chan Kim
OBJECTIVE: The aim of the study was to evaluate the short-term outcomes of KLASS-02-RCT, a multicenter randomized controlled trial comparing laparoscopic distal gastrectomy (LDG) with D2 lymphadenectomy with open distal gastrectomy (ODG). SUMMARY BACKGROUND DATA: Although several benefits of laparoscopic gastric cancer surgery have been reported, strong evidence is still limited, especially in locally advanced gastric cancer which requires extensive lymph node dissection...
February 9, 2019: Annals of Surgery
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