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LETTER
Ilaria Cavazzana, Micaela Fredi, Franco Franceschini
No abstract text is available yet for this article.
July 15, 2019: Annals of the Rheumatic Diseases
#2
Johan Rönnelid, Fabricio Espinosa-Ortega, Ingrid E Lundberg
No abstract text is available yet for this article.
July 15, 2019: Annals of the Rheumatic Diseases
#3
Frances Humby, Myles Lewis, Michael J Townsend, Costantino Pitzalis
No abstract text is available yet for this article.
July 13, 2019: Annals of the Rheumatic Diseases
#4
LETTER
Maya H Buch, Andrew Melville, Dennis G McGonagle
No abstract text is available yet for this article.
July 13, 2019: Annals of the Rheumatic Diseases
#5
Ronghan Liu, Yuehong Chen, Wenyu Fu, Shuya Wang, Yazhou Cui, Xiangli Zhao, Zi-Ning Lei, Aubryanna Hettinghouse, Jody Liu, Chao Wang, Chen Zhang, Yufei Bi, Guozhi Xiao, Zhe-Sheng Chen, Chuan-Ju Liu
OBJECTIVE: Tumour necrosis factor alpha (TNF-α) signalling plays a central role in the pathogenesis of various autoimmune diseases, particularly inflammatory arthritis. This study aimed to repurpose clinically approved drugs as potential inhibitors of TNF-α signalling in treatment of inflammatory arthritis. METHODS: In vitro and in vivo screening of an Food and Drug Administration (FDA)-approved drug library; in vitro and in vivo assays for examining the blockade of TNF actions by fexofenadine: assays for defining the anti-inflammatory activity of fexofenadine using TNF-α transgenic (TNF-tg) mice and collagen-induced arthritis in DBA/1 mice...
July 13, 2019: Annals of the Rheumatic Diseases
#6
LETTER
Manouk de Hooge, Floris A van Gaalen, Thomas Renson, Ann-Sophie De Craemer, Marleen G van de Sande, Roberta Ramonda, Karen Minde Fagerli, Lennart T H Jacobsson, Désirée van der Heijde, Dirk Elewaut, Filip Van den Bosch
No abstract text is available yet for this article.
July 13, 2019: Annals of the Rheumatic Diseases
#7
LETTER
Anthony G Wilson, John Sherwin, Emma R Dorris
No abstract text is available yet for this article.
July 12, 2019: Annals of the Rheumatic Diseases
#8
Jørgen Guldberg-Møller, Rene Lindholm Cordtz, Lars Erik Kristensen, Lene Dreyer
OBJECTIVE: To investigate time-trends and cumulative incidence of joint surgery among patients with psoriatic arthritis (PsA) compared with the general population. METHODS: In this nationwide register-based cohort study, The Danish National Patient Registry was used to identify incident PsA patients. The 5-year incidence rates (IR) and incidence rate ratios (IRR) of joint surgery were calculated in four calendar-period defined cohorts. Each patient was matched with ten non-PsA individuals from the general population cohort (GPC)...
July 12, 2019: Annals of the Rheumatic Diseases
#9
Izumi Kurata, Isao Matsumoto, Ayako Ohyama, Atsumu Osada, Hiroshi Ebe, Hoshimi Kawaguchi, Shunta Kaneko, Yuya Kondo, Hiroto Tsuboi, Azusa Tomioka, Hiroyuki Kaji, Takayuki Sumida
OBJECTIVE: An increased proportion of circulating follicular helper T (Tfh) cells was reported in rheumatoid arthritis (RA), but it remains uncertain how Tfh cells affect antibody hyposialylation. We investigated the regulation of autoantibody hyposialylation by Tfh cells in RA using murine model. METHODS: Behaviours of Tfh cells and their function on B cell promotion were analysed. Change of arthritogenicity and sialylation of autoantibodies during the course of arthritis was examined by mass spectrometry...
July 12, 2019: Annals of the Rheumatic Diseases
#10
Lina Odqvist, Zala Jevnikar, Rebecca Riise, Lisa Öberg, Magdalena Rhedin, Dag Leonard, Linda Yrlid, Sonya Jackson, Johan Mattsson, Sambit Nanda, Philip Cohen, Axel Knebel, Simon Arthur, Kristofer Thörn, Elisabet Svenungsson, Andreas Jönsen, Iva Gunnarsson, Karolina Tandre, Andrei Alexsson, Alf Kastbom, Solbritt Rantapää-Dahlqvist, Maija-Leena Eloranta, Ann-Christine Syvänen, Anders Bengtsson, Patrik Johansson, Johanna K Sandling, Christopher Sjöwall, Lars Rönnblom, Barry Collins, Outi Vaarala
OBJECTIVES: Genetic variations in TNFAIP3 (A20) de-ubiquitinase (DUB) domain increase the risk of systemic lupus erythematosus (SLE) and rheumatoid arthritis. A20 is a negative regulator of NF-κB but the role of its DUB domain and related genetic variants remain unclear. We aimed to study the functional effects of A20 DUB-domain alterations in immune cells and understand its link to SLE pathogenesis. METHODS: CRISPR/Cas9 was used to generate human U937 monocytes with A20 DUB-inactivating C103A knock-in (KI) mutation...
July 12, 2019: Annals of the Rheumatic Diseases
#11
Bianca Bech, Jette Primdahl, Astrid van Tubergen, Marieke Voshaar, Heidi A Zangi, Lurdes Barbosa, Carina Boström, Boryana Boteva, Francesco Carubbi, Françoise Fayet, Ricardo J O Ferreira, Kirsten Hoeper, Agnes Kocher, Marja Leena Kukkurainen, Vivienne Lion, Patricia Minnock, Antonella Moretti, Mwidimi Ndosi, Milena Pavic Nikolic, Michael Schirmer, Hana Smucrova, Jenny de la Torre-Aboki, Jennifer Waite-Jones, Yvonne van Eijk-Hustings
To update the European League Against Rheumatism (EULAR) recommendations for the role of the nurse in the management of chronic inflammatory arthritis (CIA) using the most up to date evidence. The EULAR standardised operating procedures were followed. A task force of rheumatologists, health professionals and patients, representing 17 European countries updated the recommendations, based on a systematic literature review and expert consensus. Higher level of evidence and new insights into nursing care for patients with CIA were added to the recommendation...
July 12, 2019: Annals of the Rheumatic Diseases
#12
LETTER
Guillaume Coiffier, Sandrine Jousse-Joulin, Divi Cornec, Ronan Garlantézec, Aurore Bleuzen, Elisabeth Diot, Patrick Jego, Alice Ballerie, Alain Lescoat
No abstract text is available yet for this article.
July 12, 2019: Annals of the Rheumatic Diseases
#13
LETTER
Shih-Wei Lai, Yu-Hung Kuo, Kuan-Fu Liao
No abstract text is available yet for this article.
July 12, 2019: Annals of the Rheumatic Diseases
#14
Francesca Minoia, Francesca Bovis, Sergio Davì, AnnaCarin Horne, Michel Fischbach, Michael Frosch, Adam Huber, Marija Jelusic, Sujata Sawhney, Deborah K McCurdy, Clóvis A Silva, Donato Rigante, Erbil Unsal, Nicolino Ruperto, Alberto Martini, Randy Q Cron, Angelo Ravelli
OBJECTIVE: To develop and validate a diagnostic score that aids in identifying macrophage activation syndrome (MAS) in patients with systemic juvenile idiopathic arthritis (sJIA). METHODS: The clinical and laboratory features of 362 patients with sJIA-associated MAS and 404 patients with active sJIA without evidence of MAS were collected in a multinational collaborative project. Eighty percent of the study population was used to develop the score and the remaining 20% constituted the validation sample...
July 11, 2019: Annals of the Rheumatic Diseases
#15
LETTER
Rachel Knevel, Tom Wj Huizinga
No abstract text is available yet for this article.
July 11, 2019: Annals of the Rheumatic Diseases
#16
Antonis Fanouriakis, George Bertsias, Dimitrios T Boumpas
No abstract text is available yet for this article.
July 11, 2019: Annals of the Rheumatic Diseases
#17
Yusuke Kawamura, Hirofumi Nakaoka, Akiyoshi Nakayama, Yukinori Okada, Ken Yamamoto, Toshihide Higashino, Masayuki Sakiyama, Toru Shimizu, Hiroshi Ooyama, Keiko Ooyama, Mitsuo Nagase, Yuji Hidaka, Yuko Shirahama, Kazuyoshi Hosomichi, Yuichiro Nishida, Ippei Shimoshikiryo, Asahi Hishida, Sakurako Katsuura-Kamano, Seiko Shimizu, Makoto Kawaguchi, Hirokazu Uemura, Rie Ibusuki, Megumi Hara, Mariko Naito, Mikiya Takao, Mayuko Nakajima, Satoko Iwasawa, Hiroshi Nakashima, Keizo Ohnaka, Takahiro Nakamura, Blanka Stiburkova, Tony R Merriman, Masahiro Nakatochi, Sahoko Ichihara, Mitsuhiro Yokota, Tappei Takada, Tatsuya Saitoh, Yoichiro Kamatani, Atsushi Takahashi, Kokichi Arisawa, Toshiro Takezaki, Keitaro Tanaka, Kenji Wakai, Michiaki Kubo, Tatsuo Hosoya, Kimiyoshi Ichida, Ituro Inoue, Nariyoshi Shinomiya, Hirotaka Matsuo
OBJECTIVE: The first ever genome-wide association study (GWAS) of clinically defined gout cases and asymptomatic hyperuricaemia (AHUA) controls was performed to identify novel gout loci that aggravate AHUA into gout. METHODS: We carried out a GWAS of 945 clinically defined gout cases and 1003 AHUA controls followed by 2 replication studies. In total, 2860 gout cases and 3149 AHUA controls (all Japanese men) were analysed. We also compared the ORs for each locus in the present GWAS (gout vs AHUA) with those in the previous GWAS (gout vs normouricaemia)...
July 8, 2019: Annals of the Rheumatic Diseases
#18
Pomme B M Poppelaars, Lilian H D van Tuyl, Maarten Boers
No abstract text is available yet for this article.
July 8, 2019: Annals of the Rheumatic Diseases
#19
Mandana Nikpour, Molla Huq, Shereen Oon
No abstract text is available yet for this article.
July 8, 2019: Annals of the Rheumatic Diseases
#20
LETTER
Nabiha Sbeih, Alexis Mathian, Marc Pineton de Chambrun, Raphael Lhote, Noël Zahr, Micheline Pha, Fleur Cohen-Aubart, Julien Haroche, Miguel Hié, Sophie Jouffroy, Neila Benameur, Hervé Devilliers, Zahir Amoura
No abstract text is available yet for this article.
July 8, 2019: Annals of the Rheumatic Diseases
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