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Bruce Baird Struminger, Sanjeev Arora
No abstract text is available yet for this article.
May 21, 2019: Annals of Internal Medicine
#2
Coleman Drake, Yuehan Zhang, Krisda H Chaiyachati, Daniel Polsky
No abstract text is available yet for this article.
May 21, 2019: Annals of Internal Medicine
#3
Bohan Lin, Wendy K Chung
Pharmacogenetics may help physicians deliver individualized treatments based on how a person's genes affect a drug's effects and metabolism. This information can help prevent adverse events or improve drug efficacy by enabling the physician to optimize dosage or to avoid a medication with adverse reactions and to prescribe an alternative therapy. This article discusses the current clinical utility of pharmacogenetic testing in the context of a patient who requires anticoagulation with warfarin.
May 21, 2019: Annals of Internal Medicine
#4
Michael D George, Joshua F Baker, Kevin Winthrop, Evo Alemao, Lang Chen, Sean Connolly, Jesse Y Hsu, Teresa A Simon, Qufei Wu, Fenglong Xie, Shuo Yang, Jeffrey R Curtis
Background: Patients with rheumatoid arthritis (RA) are at increased risk for infection after arthroplasty, yet risks of specific biologic medications are unknown. Objective: To compare risk for postoperative infection among biologics and to evaluate the risk associated with glucocorticoids. Design: Retrospective cohort study. Setting: Medicare and Truven MarketScan administrative data from January 2006 through September 2015...
May 21, 2019: Annals of Internal Medicine
#5
Siddhartha Singh, James S Goodwin, Jie Zhou, Yong-Fang Kuo, Ann B Nattinger
Background: Whether readmission rates vary by primary care physician (PCP) is unknown, although federal policy holds PCPs accountable for reducing readmissions. Objective: To determine whether 30-day readmission rates vary by PCP. Design: Retrospective cohort study using marginal models and multilevel logistic regression with 100% of data on Texas Medicare claims from 2008 to 2015. Setting: Texas. Participants: Patients discharged alive between 1 January 2008 and 30 November 2015 who had a PCP in the prior year and whose PCP had at least 50 admissions in the study period...
May 21, 2019: Annals of Internal Medicine
#6
Bheeshma Ravi, Gillian Hawker
No abstract text is available yet for this article.
May 21, 2019: Annals of Internal Medicine
#7
Prevalence, Recognition of Work-Relatedness, and Effect on Work of Low Back Pain Among U.S. Workers.
Sara E Luckhaupt, James M Dahlhamer, Gabriella T Gonzales, Ming-Lun Lu, Matthew Groenewold, Marie Haring Sweeney, Brian W Ward
No abstract text is available yet for this article.
May 14, 2019: Annals of Internal Medicine
#8
M Hong Nguyen, Cornelius J Clancy, A William Pasculle, Peter G Pappas, George Alangaden, George A Pankey, Bryan H Schmitt, Altaf Rasool, Melvin P Weinstein, Raymond Widen, Diana R Hernandez, Donna M Wolk, Thomas J Walsh, John R Perfect, Mollie N Wilson, Eleftherios Mylonakis
Background: Blood cultures, the gold standard for diagnosing bloodstream infections (BSIs), are insensitive and limited by prolonged time to results. The T2Bacteria Panel (T2 Biosystems) is a direct-from-blood, nonculture test that identifies the most common ESKAPE bacteria (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Escherichia coli). Objective: To assess performance of the T2Bacteria Panel in diagnosing suspected BSIs in adults...
May 14, 2019: Annals of Internal Medicine
#9
Ronald Laracuente, Marc Paul Waase, Isha Kalia, Arthur A M Wilde, Wendy K Chung
Sudden death in a family is associated with serious anxiety among family members. Assessing the cause of death may help determine the risk for other family members, thus alleviating some anxiety. In some cases, the cause of death may be evident on autopsy; however, in cases of arrhythmias, standard autopsy will not reveal the cause of death. Evaluation of the circumstances of death, medical history of the deceased, and results of genetic testing may reveal a diagnosis. Once a diagnosis is made, relatives should receive genetic testing and clinical assessment to stratify their risk...
May 14, 2019: Annals of Internal Medicine
#10
Mollie Kotzen
No abstract text is available yet for this article.
May 14, 2019: Annals of Internal Medicine
#11
David A Weinrib, Gerald A Capraro
No abstract text is available yet for this article.
May 14, 2019: Annals of Internal Medicine
#12
Susan J Bersoff-Matcha, Christine Chamberlain, Christian Cao, Cindy Kortepeter, William H Chong
Background: Use of sodium-glucose cotransporter-2 (SGLT2) inhibitors has been associated with Fournier gangrene (FG), a rare urologic emergency characterized by necrotizing infection of the external genitalia, perineum, and perianal region. Objective: To describe and compare reported cases of FG in diabetic adults receiving treatment with SGLT2 inhibitors or other antiglycemic agents. Design: Descriptive case series. Setting: U...
May 7, 2019: Annals of Internal Medicine
#13
Ali Duarte-García, Eric L Matteson, Nilay D Shah
No abstract text is available yet for this article.
May 7, 2019: Annals of Internal Medicine
#14
Joshua D Wallach, Harlan M Krumholz
No abstract text is available yet for this article.
May 7, 2019: Annals of Internal Medicine
#15
Michael Rahbek Schmidt, Lars Søndergaard
No abstract text is available yet for this article.
May 7, 2019: Annals of Internal Medicine
#16
Deborah Stiles, Paul S Appelbaum
Patients and research participants have indicated that privacy of their genetic test results is an important concern, particularly with respect to insurance coverage. Internists and other physicians whose patients ask about legal protections for information generated by genome sequencing for clinical purposes can provide both reassurance and caution. Protections for medical information in general, as well as laws in some states that provide additional safeguards for genetic data, should reassure patients that this information will remain private...
May 7, 2019: Annals of Internal Medicine
#17
Emmanuelle Le Moigne, Serge Timsit, Douraied Ben Salem, Romain Didier, Yannick Jobic, Nicolas Paleiron, Raphael Le Mao, Thierry Joseph, Clément Hoffmann, Angelina Dion, Jean Rousset, Grégoire Le Gal, Karine Lacut, Christophe Leroyer, Dominique Mottier, Francis Couturaud
Background: Pulmonary embolism (PE) is associated with increased risk for ischemic stroke, but the underlying mechanism remains unclear. The authors hypothesized that paradoxical embolism through patent foramen ovale (PFO) should be the main mechanism. Objective: To determine the frequency of recent ischemic stroke in patients with symptomatic PE according to whether PFO was detected. Design: Prospective cohort study with masked assessment of stroke outcomes...
May 7, 2019: Annals of Internal Medicine
#18
Athina Tatsioni, Fotini B Karassa, Steven N Goodman, Deborah A Zarin, Daniele Fanelli, John P A Ioannidis
No abstract text is available yet for this article.
May 7, 2019: Annals of Internal Medicine
#19
Vidyulata Kamath, Bruce Leff
No abstract text is available yet for this article.
April 30, 2019: Annals of Internal Medicine
#20
Mary E Reed, Jie Huang, Rahul Parikh, Andrea Millman, Dustin W Ballard, Irwin Barr, Craig Wargon
No abstract text is available yet for this article.
April 30, 2019: Annals of Internal Medicine
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