journal
https://read.qxmd.com/read/36913693/effectiveness-of-molnupiravir-and-nirmatrelvir-ritonavir-in-hospitalized-patients-with-covid-19-a-target-trial-emulation-study
#1
JOURNAL ARTICLE
Eric Yuk Fai Wan, Vincent Ka Chun Yan, Anna Hoi Ying Mok, Boyuan Wang, Wanchun Xu, Franco Wing Tak Cheng, Francisco Tsz Tsun Lai, Celine Sze Ling Chui, Xue Li, Carlos King Ho Wong, Philip Hei Li, Benjamin John Cowling, Ivan Fan Ngai Hung, Chak Sing Lau, Ian Chi Kei Wong, Esther Wai Yin Chan
BACKGROUND: Whether hospitalized patients benefit from COVID-19 oral antivirals is uncertain. OBJECTIVE: To examine the real-world effectiveness of molnupiravir and nirmatrelvir-ritonavir in hospitalized patients with COVID-19 during the Omicron outbreak. DESIGN: Target trial emulation study. SETTING: Electronic health databases in Hong Kong. PARTICIPANTS: The molnupiravir emulated trial included hospitalized patients with COVID-19 aged 18 years or older between 26 February and 18 July 2022 ( n  = 16 495)...
March 14, 2023: Annals of Internal Medicine
https://read.qxmd.com/read/36913692/overweight-and-obesity-current-clinical-challenges
#2
JOURNAL ARTICLE
Christine Laine, Christina C Wee
No abstract text is available yet for this article.
March 14, 2023: Annals of Internal Medicine
https://read.qxmd.com/read/36913691/written-by-humans-or-artificial-intelligence-that-is-the-question
#3
EDITORIAL
Michiel Schinkel, Ketan Paranjape, Prabath Nanayakkara
No abstract text is available yet for this article.
March 14, 2023: Annals of Internal Medicine
https://read.qxmd.com/read/36913690/cardiac-arrest-during-delivery-hospitalization-a-cohort-study
#4
JOURNAL ARTICLE
Nicole D Ford, Carla L DeSisto, Romeo R Galang, Elena V Kuklina, Laurence S Sperling, Jean Y Ko
BACKGROUND: Estimates of cardiac arrest occurring during delivery guide evidence-based strategies to reduce pregnancy-related death. OBJECTIVE: To investigate rate of, maternal characteristics associated with, and survival after cardiac arrest during delivery hospitalization. DESIGN: Retrospective cohort study. SETTING: U.S. acute care hospitals, 2017 to 2019. PARTICIPANTS: Delivery hospitalizations among women aged 12 to 55 years included in the National Inpatient Sample database...
March 14, 2023: Annals of Internal Medicine
https://read.qxmd.com/read/36913689/annals-video-summary-effect-of-yoga-on-frailty-in-older-adults-a-systematic-review
#5
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
March 14, 2023: Annals of Internal Medicine
https://read.qxmd.com/read/36913688/cardiac-amyloidosis
#6
REVIEW
Michelle Weisfelner Bloom, Peter D Gorevic
Amyloidosis is a pathologic and clinical condition resulting from the accumulation of insoluble aggregates of misfolded proteins in tissues. Extracellular deposition of amyloid fibrils in the myocardium leads to cardiac amyloidosis, which is often overlooked as a cause of diastolic heart failure. Although cardiac amyloidosis was previously believed to have a poor prognosis, recent advances in diagnosis and treatment have emphasized the importance of early recognition and changed management of this condition...
March 14, 2023: Annals of Internal Medicine
https://read.qxmd.com/read/36913687/effect-of-yoga-on-frailty-in-older-adults-a-systematic-review
#7
REVIEW
Julia Loewenthal, Kim E Innes, Margalit Mitzner, Carol Mita, Ariela R Orkaby
BACKGROUND: Yoga, a multicomponent mind-body practice, improves several domains of physical and psychological health and may affect frailty in older adults. PURPOSE: To evaluate the available trial evidence on the effect of yoga-based interventions on frailty in older adults. DATA SOURCES: MEDLINE, EMBASE, and Cochrane Central from their inception to 12 December 2022. STUDY SELECTION: Randomized controlled trials evaluating the effect of yoga-based interventions, including at least 1 session of physical postures, on a validated frailty scale or single-item markers of frailty in adults aged 65 years or older...
March 14, 2023: Annals of Internal Medicine
https://read.qxmd.com/read/36913686/erythema-gyratum-repens-secondary-to-pulmonary-tuberculosis
#8
JOURNAL ARTICLE
Caitlin A Contag, Nolan Maloney, Ralph Tayyar, Maria Alexandrova Aleshin, Roberto Andres Novoa, Dora Yukwai Ho
No abstract text is available yet for this article.
March 14, 2023: Annals of Internal Medicine
https://read.qxmd.com/read/36913685/annals-graphic-medicine-opinion-someone-does-not-belong
#9
JOURNAL ARTICLE
Rachel Weber
No abstract text is available yet for this article.
March 14, 2023: Annals of Internal Medicine
https://read.qxmd.com/read/36877978/what-is-the-current-role-of-an-over-the-scope-clip-used-as-first-line-endoscopic-hemostasis-in-patients-with-nonvariceal-upper-gastrointestinal-bleeding
#10
JOURNAL ARTICLE
Alan N Barkun, Ali A Alali
No abstract text is available yet for this article.
March 7, 2023: Annals of Internal Medicine
https://read.qxmd.com/read/36877977/in-adults-receiving-mechanical-ventilation-selective-decontamination-of-the-digestive-tract-reduces-hospital-mortality
#11
JOURNAL ARTICLE
Naomi P O'Grady
Hammond NE, Myburgh J, Seppelt I, et al. Association between selective decontamination of the digestive tract and in-hospital mortality in intensive care unit patients receiving mechanical ventilation: a systematic review and meta-analysis. JAMA. 2022;328:1922-34. 36286098.
March 7, 2023: Annals of Internal Medicine
https://read.qxmd.com/read/36877976/in-adults-with-delirium-in-the-icu-haloperidol-did-not-increase-number-of-days-alive-out-of-the-hospital-at-90-d
#12
JOURNAL ARTICLE
Michael Tanner
Andersen-Ranberg NC, Poulsen LM, Perner A, et al. Haloperidol for the treatment of delirium in ICU patients. N Engl J Med. 2022;387:2425-35. 36286254.
March 7, 2023: Annals of Internal Medicine
https://read.qxmd.com/read/36877975/in-symptomatic-af-cryoballoon-ablation-reduced-progression-to-persistent-af-vs-antiarrhythmic-therapy-at-3-y
#13
JOURNAL ARTICLE
Nigel S Tan
Andrade JG, Deyell MW, Macle L, et al. Progression of atrial fibrillation after cryoablation or drug therapy. N Engl J Med. 2023;388:105-16. 36342178.
March 7, 2023: Annals of Internal Medicine
https://read.qxmd.com/read/36877974/in-ckd-once-daily-empagliflozin-reduced-progression-of-kidney-disease-or-cv-death-at-2-y
#14
JOURNAL ARTICLE
Y Diana Kwong, Chi-Yuan Hsu
EMPA-KIDNEY Collaborative Group; Herrington WG, Staplin N, Wanner C, et al. Empagliflozin in patients with chronic kidney disease. N Engl J Med. 2023;388:117-27. 36331190.
March 7, 2023: Annals of Internal Medicine
https://read.qxmd.com/read/36877973/sglt2-inhibitors-reduce-adverse-renal-and-cv-outcomes-in-patients-with-or-without-diabetes
#15
JOURNAL ARTICLE
Tejas Patel
Nuffield Department of Population Health Renal Studies Group; SGLT2 inhibitor Meta-Analysis Cardio-Renal Trialists' Consortium. Impact of diabetes on the effects of sodium glucose co-transporter-2 inhibitors on kidney outcomes: collaborative meta-analysis of large placebo-controlled trials. Lancet. 2022;400:1788-801. 36351458.
March 7, 2023: Annals of Internal Medicine
https://read.qxmd.com/read/36877972/antihypertensive-therapy-reduced-incident-dementia-vs-placebo-at-a-median-4-3-y
#16
JOURNAL ARTICLE
Chirag Bavishi
Peters R, Xu Y, Fitzgerald O, et al. Blood pressure lowering and prevention of dementia: an individual patient data meta-analysis. Eur Heart J. 2022;43:4980-90. 36282295.
March 7, 2023: Annals of Internal Medicine
https://read.qxmd.com/read/36877971/in-acute-hf-in-the-ed-a-risk-based-management-algorithm-vs-usual-care-reduced-a-composite-clinical-outcome-at-30-d
#17
JOURNAL ARTICLE
Mitchell Levine
Lee DS, Straus SE, Farkouh ME, et al. Trial of an intervention to improve acute heart failure outcomes. N Engl J Med. 2023;388:22-32. 36342109.
March 7, 2023: Annals of Internal Medicine
https://read.qxmd.com/read/36877970/in-adults-with-acute-hf-high-intensity-care-vs-usual-care-reduced-a-composite-of-death-or-hf-readmission-at-180-d
#18
JOURNAL ARTICLE
Mitchell Levine
Mebazaa A, Davison B, Chioncel O, et al. Safety, tolerability and efficacy of up-titration of guideline-directed medical therapies for acute heart failure (STRONG-HF): a multinational, open-label, randomised, trial. Lancet. 2022;400:1938-52. 36356631.
March 7, 2023: Annals of Internal Medicine
https://read.qxmd.com/read/36877969/in-af-underdosing-of-doacs-was-not-linked-to-reduced-bleeding
#19
JOURNAL ARTICLE
Andrew Dunn
Caso V, de Groot JR, Sanmartin Fernandez M, et al. Outcomes and drivers of inappropriate dosing of non-vitamin K antagonist oral anticoagulants (NOACs) in patients with atrial fibrillation: a systematic review and meta-analysis. Heart. 2023;109:178-85. 36316100.
March 7, 2023: Annals of Internal Medicine
https://read.qxmd.com/read/36877968/in-advanced-progressive-ckd-discontinuing-ras-inhibitors-did-not-improve-egfr-at-3-y
#20
JOURNAL ARTICLE
Donald Molony, Andrew Horvit, Dia Waguespack
Bhandari S, Mehta S, Khwaja A, et al. Renin-angiotensin system inhibition in advanced chronic kidney disease. N Engl J Med. 2022;387:2021-32. 36326117.
March 7, 2023: Annals of Internal Medicine
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