journal

Annals of Internal Medicine

journal
https://read.qxmd.com/read/32634024/how-to-quantify-and-interpret-treatment-effects-in-comparative-clinical-studies-of-covid-19
#1
Zachary R McCaw, Lu Tian, Jason L Vassy, Christine Seel Ritchie, Chien-Chang Lee, Dae Hyun Kim, Lee-Jen Wei
Clinical trials of treatments for coronavirus disease 2019 (COVID-19) draw intense public attention. More than ever, valid, transparent, and intuitive summaries of the treatment effects, including efficacy and harm, are needed. In recently published and ongoing randomized comparative trials evaluating treatments for COVID-19, time to a positive outcome, such as recovery or improvement, has repeatedly been used as either the primary or key secondary end point. Because patients may die before recovery or improvement, data analysis of this end point faces a competing risk problem...
July 7, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32628533/analysis-of-response-data-for-assessing-treatment-effects-in-comparative-clinical-studies
#2
Bo Huang, Lu Tian, Zachary R McCaw, Xiaodong Luo, Enayet Talukder, Mace Rothenberg, Wanling Xie, Toni K Choueiri, Dae Hyun Kim, Lee-Jen Wei
In comparative studies, treatment effect is often assessed using a binary outcome that indicates response to the therapy. Commonly used summary measures for response include the cumulative and current response rates at a specific time point. The current response rate is sometimes called the probability of being in response (PBIR), which regards a patient as a responder only if they have achieved and remain in response at present. The methods used in practice for estimating these rates, however, may not be appropriate...
July 7, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32628532/association-between-oral-corticosteroid-bursts-and-severe-adverse-events-a-nationwide-population-based-cohort-study
#3
Tsung-Chieh Yao, Ya-Wen Huang, Sheng-Mao Chang, Shun-Yu Tsai, Ann Chen Wu, Hui-Ju Tsai
BACKGROUND: Long-term use of oral corticosteroids has known adverse effects, but the risk from brief oral steroid bursts (≤14 days) is largely unknown. OBJECTIVE: To examine the associations between steroid bursts and severe adverse events, specifically gastrointestinal (GI) bleeding, sepsis, and heart failure. DESIGN: Self-controlled case series. SETTING: Entire National Health Insurance Research Database of medical claims records in Taiwan...
July 7, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32628531/clinical-benefits-harms-and-cost-effectiveness-of-breast-cancer-screening-for-survivors-of-childhood-cancer-treated-with-chest-radiation-a-comparative-modeling-study
#4
Jennifer M Yeh, Kathryn P Lowry, Clyde B Schechter, Lisa R Diller, Oguzhan Alagoz, Gregory T Armstrong, John M Hampton, Wendy Leisenring, Qi Liu, Jeanne S Mandelblatt, Diana L Miglioretti, Chaya S Moskowitz, Kevin C Oeffinger, Amy Trentham-Dietz, Natasha K Stout
BACKGROUND: Surveillance with annual mammography and breast magnetic resonance imaging (MRI) is recommended for female survivors of childhood cancer treated with chest radiation, yet benefits, harms, and costs are uncertain. OBJECTIVE: To compare the benefits, harms, and cost-effectiveness of breast cancer screening strategies in childhood cancer survivors. DESIGN: Collaborative simulation modeling using 2 Cancer Intervention and Surveillance Modeling Network breast cancer models...
July 7, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32628530/burst-case-scenario-why-shorter-may-not-be-any-better-when-it-comes-to-corticosteroids
#5
Beth I Wallace, Akbar K Waljee
No abstract text is available yet for this article.
July 7, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32628529/autologous-hematopoietic-stem-cell-transplantation-for-susac-syndrome
#6
LETTER
Jose G Ruiz de Morales, Miguel Cordero-Coma, Montserrat Rovira, Sara Calleja-Antolin, Gerard Espinosa, Natalia de Las Heras
No abstract text is available yet for this article.
July 7, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32628537/obesity-and-covid-19-in-new-york-city-a-retrospective-cohort-study
#7
LETTER
Parag Goyal, Joanna Bryan Ringel, Mangala Rajan, Justin J Choi, Laura C Pinheiro, Han A Li, Graham T Wehmeyer, Mark N Alshak, Assem Jabri, Edward J Schenck, Ruijun Chen, Michael J Satlin, Thomas R Campion, Musarrat Nahid, Maria Plataki, Katherine L Hoffman, Evgeniya Reshetnyak, Nathaniel Hupert, Evelyn M Horn, Fernando J Martinez, Roy M Gulick, Monika M Safford
No abstract text is available yet for this article.
July 6, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32628536/qualitative-assessment-of-rapid-system-transformation-to-primary-care-video-visits-at-an-academic-medical-center
#8
Malathi Srinivasan, Steven Asch, Stacie Vilendrer, Samuel Crandall Thomas, Rika Bajra, Linda Barman, Lauren Michelle Edwards, Heather Filipowicz, Lena Giang, Olivia Jee, Megan Mahoney, Ian Nelligan, Anuradha Jayant Phadke, Elise Torres, Maja Artandi
BACKGROUND: The coronavirus disease 2019 pandemic spurred health systems across the world to quickly shift from in-person visits to safer video visits. OBJECTIVE: To seek stakeholder perspectives on video visits' acceptability and effect 3 weeks after near-total transition to video visits. DESIGN: Semistructured qualitative interviews. SETTING: 6 Stanford general primary care and express care clinics at 6 northern California sites, with 81 providers, 123 staff, and 97 614 patient visits in 2019...
July 6, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32628535/regulatory-t-cells-for-treating-patients-with-covid-19-and-acute-respiratory-distress-syndrome-two-case-reports
#9
LETTER
Douglas E Gladstone, Bo Soo Kim, Kathy Mooney, Andrew H Karaba, Franco R D'Alessio
No abstract text is available yet for this article.
July 6, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32628534/clinical-validity-of-serum-antibodies-to-sars-cov-2-a-case-control-study
#10
Giorgio Caturegli, Joshua Materi, Brittney M Howard, Patrizio Caturegli
BACKGROUND: The clinical utility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies remains undefined. OBJECTIVE: To determine the clinical validity and utility of SARS-CoV-2 antibodies. DESIGN: Case-control study. SETTING: First month of testing for coronavirus disease 2019 (COVID-19) by using a nucleic acid amplification test (NAAT) on nasopharyngeal swabs at the Johns Hopkins Hospital, Baltimore, Maryland (11 066 persons)...
July 6, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32614641/annals-graphic-medicine-how-the-virus-stole-anatomy
#11
Stefan Tigges, Patricia J Ward
No abstract text is available yet for this article.
July 2, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32614640/reopening-colleges-and-universities-during-the-covid-19-pandemic
#12
Mark S Wrighton, Steven J Lawrence
No abstract text is available yet for this article.
July 2, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32614639/urgent-issues-facing-immigrant-physicians-in-the-united-states-in-the-covid-19-era
#13
EDITORIAL
Vivekanand Tiwari, Abhishek Bhardwaj, Bhavin Sonani, Atul C Mehta
No abstract text is available yet for this article.
July 2, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32614638/how-to-safely-reopen-colleges-and-universities-during-covid-19-experiences-from-taiwan
#14
Shao-Yi Cheng, C Jason Wang, April Chiung-Tao Shen, Shan-Chwen Chang
Reopening colleges and universities during the coronavirus disease 2019 (COVID-19) pandemic poses a special challenge worldwide. Taiwan is one of the few countries where schools are functioning normally. To secure the safety of students and staff, the Ministry of Education in Taiwan established general guidelines for college campuses. The guidelines delineated creation of a task force at each university; school-based risk screening based on travel history, occupation, contacts, and clusters; measures on self-management of health and quarantine; general hygiene measures (including wearing masks indoors); principles on ventilation and sanitization; regulations on school assemblies; a process for reporting suspected cases; and policies on school closing and make-up classes...
July 2, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32598226/extreme-risk-protection-orders-in-washington-a-statewide-descriptive-study
#15
Ali Rowhani-Rahbar, M Alex Bellenger, Lauren Gibb, Heather Chesnut, Madison Lowry-Schiller, Emma Gause, Miriam J Haviland, Frederick P Rivara
BACKGROUND: In the United States, 74% of homicides and 51% of suicides involve firearms. Using extreme risk protection order (ERPO) laws, petitioners can request restricting firearm access for individuals (known as "respondents") who pose harm a risk to themselves or others. OBJECTIVE: To characterize respondents and circumstances of ERPOs. DESIGN: Descriptive study. SETTING: State of Washington. PARTICIPANTS: All ERPO respondents during 8 December 2016 to 10 May 2019...
June 30, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32598225/the-right-diabetes-medication-for-the-right-patient-for-the-right-outcome-can-a-network-meta-analysis-help-us-decide
#16
Christine G Lee, William T Cefalu
No abstract text is available yet for this article.
June 30, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32598224/thank-you-for-your-service-from-the-sidelines-of-the-pandemic
#17
Niharika Sathe
No abstract text is available yet for this article.
June 30, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32598223/different-interpretations-of-the-same-genetic-data
#18
LETTER
Jeffrey A SoRelle, Amber P Gemmell, Theodora S Ross
No abstract text is available yet for this article.
June 30, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32598222/extreme-risk-protection-orders-in-washington-a-tool-for-reducing-the-lethality-of-dangerous-behaviors
#19
Shannon Frattaroli, Nathan A Irvin
No abstract text is available yet for this article.
June 30, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32598221/united
#20
Ami L DeWaters
No abstract text is available yet for this article.
June 30, 2020: Annals of Internal Medicine
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