journal
https://read.qxmd.com/read/32960645/patient-trajectories-among-persons-hospitalized-for-covid-19-a-cohort-study
#1
Brian T Garibaldi, Jacob Fiksel, John Muschelli, Matthew L Robinson, Masoud Rouhizadeh, Jamie Perin, Grant Schumock, Paul Nagy, Josh H Gray, Harsha Malapati, Mariam Ghobadi-Krueger, Timothy M Niessen, Bo Soo Kim, Peter M Hill, M Shafeeq Ahmed, Eric D Dobkin, Renee Blanding, Jennifer Abele, Bonnie Woods, Kenneth Harkness, David R Thiemann, Mary G Bowring, Aalok B Shah, Mei-Cheng Wang, Karen Bandeen-Roche, Antony Rosen, Scott L Zeger, Amita Gupta
BACKGROUND: Risk factors for progression of coronavirus 2019 (COVID-19) to severe disease or death are underexplored in U.S. cohorts. OBJECTIVE: To determine the factors on hospital admission that are predictive of severe disease or death from COVID-19. DESIGN: Retrospective cohort analysis. SETTING: Five hospitals in the Maryland and Washington, DC, area. PATIENTS: 832 consecutive COVID-19 admissions from 4 March to 24 April 2020, with follow-up through 27 June 2020...
September 22, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32956607/primary-care-panel-size-how-you-measure-makes-a-difference
#2
LETTER
Michael F Mayo-Smith
No abstract text is available yet for this article.
September 22, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32956606/annals-graphic-medicine-silence
#3
Michael S Shen
No abstract text is available yet for this article.
September 22, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32956605/the-u-s-department-of-veterans-affairs-and-u-s-department-of-defense-guideline-for-the-management-of-dyslipidemia-is-moderate-risk-reduction-enough
#4
Alison L Bailey, Charles L Campbell
No abstract text is available yet for this article.
September 22, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32956604/risk-for-serious-infection-with-low-dose-glucocorticoids-in-patients-with-rheumatoid-arthritis-a-cohort-study
#5
Michael D George, Joshua F Baker, Kevin Winthrop, Jesse Y Hsu, Qufei Wu, Lang Chen, Fenglong Xie, Huifeng Yun, Jeffrey R Curtis
BACKGROUND: Low-dose glucocorticoids are frequently used for the management of rheumatoid arthritis (RA) and other chronic conditions, but the safety of long-term use remains uncertain. OBJECTIVE: To quantify the risk for hospitalized infection with long-term use of low-dose glucocorticoids in patients with RA receiving stable disease-modifying antirheumatic drug (DMARD) therapy. DESIGN: Retrospective cohort study. SETTING: Medicare claims data and Optum's deidentified Clinformatics Data Mart database from 2006 to 2015...
September 22, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32956603/distinguishing-high-performing-health-systems-using-a-composite-of-publicly-reported-measures-of-ambulatory-care
#6
Denis Agniel, Amelia Haviland, Paul Shekelle, Adam Scherling, Cheryl L Damberg
BACKGROUND: Payers and policymakers are rewarding high-performing health care providers on the basis of summaries of overall quality performance, and the methods they use for measuring performance are increasingly important. OBJECTIVE: To develop and evaluate a measure that ranks health care systems by ambulatory care quality. DESIGN: Systems were ranked using a composite model that summarizes individual measures of quality, accounts for their correlation, and does not require health care systems to report every measure...
September 22, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32956602/human-papillomavirus-immunization-and-the-elimination-of-cervical-carcinoma
#7
Timothy Palmer, Kate Cuschieri
No abstract text is available yet for this article.
September 22, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32956601/interventions-to-improve-statin-tolerance-and-adherence-in-patients-at-risk-for-cardiovascular-disease-a-systematic-review-for-the-2020-u-s-department-of-veterans-affairs-and-u-s-department-of-defense-guidelines-for-management-of-dyslipidemia
#8
James T Reston, Andrew Buelt, Mark P Donahue, Brian Neubauer, Elena Vagichev, Kristy McShea
BACKGROUND: Strategies to improve patients' tolerance of and adherence to statins may enhance the effectiveness of dyslipidemia treatment in those at risk for cardiovascular disease (CVD). PURPOSE: To assess the benefits and harms of interventions to improve statin adherence in patients at risk for CVD. DATA SOURCES: MEDLINE, EMBASE, PubMed, and the Cochrane Library from December 2013 through May 2019 (English language only). STUDY SELECTION: Systematic reviews (SRs), randomized controlled trials (RCTs), and cohort studies that addressed interventions for improving statin tolerance and adherence...
September 22, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32956600/prevalence-of-human-papillomavirus-and-estimation-of-human-papillomavirus-vaccine-effectiveness-in-thimphu-bhutan-in-2011-2012-and-2018-a-cross-sectional-study
#9
Iacopo Baussano, Ugyen Tshomo, Vanessa Tenet, Daniëlle A M Heideman, Tshering Wangden, Silvia Franceschi, Gary M Clifford
BACKGROUND: Bhutan implemented a national program for human papillomavirus (HPV) vaccination in 2010 involving girls aged 12 to 18 years and achieving nearly 90% coverage. OBJECTIVE: To estimate HPV vaccine effectiveness in a city in Bhutan. DESIGN: 2 cross-sectional surveys, 2011-2012 and 2018. SETTING: 2 hospitals in Thimphu, capital of Bhutan. PARTICIPANTS: Sexually active women aged 17 to 29 years: 1445 participants from the baseline survey and 1595 from the repeated survey...
September 22, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32956599/update-alert-4-risks-and-impact-of-angiotensin-converting-enzyme-inhibitors-or-angiotensin-receptor-blockers-on-sars-cov-2-infection-in-adults
#10
LETTER
Katherine Mackey, Devan Kansagara, Kathryn Vela
No abstract text is available yet for this article.
September 22, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32956598/for-the-love-of-quality
#11
Kavita K Patel
No abstract text is available yet for this article.
September 22, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32956597/management-of-dyslipidemia-for-cardiovascular-disease-risk-reduction-synopsis-of-the-2020-updated-u-s-department-of-veterans-affairs-and-u-s-department-of-defense-clinical-practice-guideline
#12
Patrick G O'Malley, Michael J Arnold, Cathy Kelley, Lance Spacek, Andrew Buelt, Sundar Natarajan, Mark P Donahue, Elena Vagichev, Jennifer Ballard-Hernandez, Amanda Logan, Lauren Thomas, Joan Ritter, Brian E Neubauer, John R Downs
DESCRIPTION: In June 2020, the U.S. Department of Veterans Affairs (VA) and U.S. Department of Defense (DoD) released a joint update of their clinical practice guideline for managing dyslipidemia to reduce cardiovascular disease risk in adults. This synopsis describes the major recommendations. METHODS: On 6 August to 9 August 2019, the VA/DoD Evidence-Based Practice Work Group (EBPWG) convened a joint VA/DoD guideline development effort that included clinical stakeholders and conformed to the Institute of Medicine's tenets for trustworthy clinical practice guidelines...
September 22, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32956596/rethinking-the-balance-of-risks-and-rewards-of-chronic-low-dose-glucocorticoids-in-rheumatoid-arthritis
#13
Dana E Orange, Bella Mehta
No abstract text is available yet for this article.
September 22, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32941059/managing-covid-19-in-a-novel-rapidly-deployable-community-isolation-quarantine-facility
#14
Ming Li Chia, Dickson Hong Him Chau, Kheng Sit Lim, Christopher Wei Yang Liu, Hiang Khoon Tan, Yan Ru Tan
Singapore is one of the most densely populated small island-states in the world. During the coronavirus disease 2019 (COVID-19) pandemic, Singapore implemented large-scale institutional isolation units called Community Care Facilities (CCFs) to combat the outbreak in the community by housing low-risk COVID-19 patients from April to August 2020. The CCFs were created rapidly by converting existing public spaces and used a protocolized system, augmented by telemedicine to enable a low health care worker-patient ratio (98 health care workers for 3200 beds), to operate these unique facilities...
September 17, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32941052/transmission-of-sars-cov-2-a-review-of-viral-host-and-environmental-factors
#15
Eric A Meyerowitz, Aaron Richterman, Rajesh T Gandhi, Paul E Sax
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic agent of coronavirus disease 2019 (COVID-19), has spread globally in a few short months. Substantial evidence now supports preliminary conclusions about transmission that can inform rational, evidence-based policies and reduce misinformation on this critical topic. This article presents a comprehensive review of the evidence on transmission of this virus. Although several experimental studies have cultured live virus from aerosols and surfaces hours after inoculation, the real-world studies that detect viral RNA in the environment report very low levels, and few have isolated viable virus...
September 17, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32931328/characteristics-of-covid-19-in-homeless-shelters-a-community-based-surveillance-study
#16
Julia H Rogers, Amy C Link, Denise McCulloch, Elisabeth Brandstetter, Kira L Newman, Michael L Jackson, James P Hughes, Janet A Englund, Michael Boeckh, Nancy Sugg, Misja Ilcisin, Thomas R Sibley, Kairsten Fay, Jover Lee, Peter Han, Melissa Truong, Matthew Richardson, Deborah A Nickerson, Lea M Starita, Trevor Bedford, Helen Y Chu
BACKGROUND: Homeless shelters are a high-risk setting for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission because of crowding and shared hygiene facilities. OBJECTIVE: To investigate SARS-CoV-2 case counts across several adult and family homeless shelters in a major metropolitan area. DESIGN: Cross-sectional, community-based surveillance study. (ClinicalTrials.gov: NCT04141917). SETTING: 14 homeless shelters in King County, Washington...
September 15, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32931327/developing-guidelines-before-during-and-after-the-covid-19-pandemic
#17
EDITORIAL
Zachary Munn, Sara Twaddle, Duncan Service, Elaine Harrow, Patrick Mbah Okwen, Holger Schünemann, Per Olav Vandvik
No abstract text is available yet for this article.
September 15, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32931326/the-covid-nma-project-building-an-evidence-ecosystem-for-the-covid-19-pandemic
#18
EDITORIAL
Isabelle Boutron, Anna Chaimani, Joerg J Meerpohl, Asbjørn Hróbjartsson, Declan Devane, Gabriel Rada, David Tovey, Giacomo Grasselli, Philippe Ravaud
No abstract text is available yet for this article.
September 15, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32926799/effectiveness-of-curcuma-longa-extract-for-the-treatment-of-symptoms-and-effusion-synovitis-of-knee-osteoarthritis-a-randomized-trial
#19
Zhiqiang Wang, Graeme Jones, Tania Winzenberg, Guoqi Cai, Laura L Laslett, Dawn Aitken, Ingrid Hopper, Ambrish Singh, Robert Jones, Jurgen Fripp, Changhai Ding, Benny Antony
BACKGROUND: Current pharmacologic therapies for patients with osteoarthritis are suboptimal. OBJECTIVE: To determine the efficacy of Curcuma longa extract (CL) for reducing knee symptoms and effusion-synovitis in patients with symptomatic knee osteoarthritis and knee effusion-synovitis. DESIGN: Randomized, double-blind, placebo-controlled trial. (Australian New Zealand Clinical Trials Registry: ACTRN12618000080224). SETTING: Single-center study with patients from southern Tasmania, Australia...
September 15, 2020: Annals of Internal Medicine
https://read.qxmd.com/read/32926798/policy-recommendations-to-promote-prescription-drug-competition-a-position-paper-from-the-american-college-of-physicians
#20
Hilary Daniel, Josh Serchen, Thomas G Cooney
The prescription drug market in the United States relies on competition to keep prices reasonable. Although many policies have been implemented to spur competition and decrease costs for patients, these policies may be outdated and should be redesigned and updated to achieve success in the current prescription drug market. In this paper, the American College of Physicians (ACP) proposes that new policies should be implemented to prevent market manipulation, help lower-cost alternatives make it to the market faster, and ensure a robust and competitive market for generic and biosimilar drugs...
September 15, 2020: Annals of Internal Medicine
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