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American Journal of Tropical Medicine and Hygiene

https://read.qxmd.com/read/38593793/distribution-and-seasonal-variation-of-phlebotomus-and-sergentomyia-sand-fly-populations-in-bhutan
#1
JOURNAL ARTICLE
Tenzin Wangdi, Sanath Senanayake, Sithar Dorjee, Tashi Tobgay, Guofa Zhou, Sachee B Piyasiri, W M Lakshika I Weerasinghe, Nadira Karunaweera
Leishmaniasis is considered one of the neglected tropical diseases in the world. Although Bhutan is a member of the visceral leishmaniasis elimination consortium in South Asia, not much attention has been accorded to the disease because of its low incidence. The vector that transmits Leishmania remains poorly understood. In this backdrop, sand-fly surveys were regularly conducted at multiple sites where leishmaniasis cases have been reported in Bhutan. Collections were made using CDC light traps and cattle-baited net traps in 15 villages from February 2019 to May 2022...
April 9, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38593792/a-mixed-methods-evaluation-of-mainstreaming-mass-drug-administration-for-schistosomiasis-and-soil-transmitted-helminthiasis-in-four-districts-of-nigeria
#2
JOURNAL ARTICLE
Emily Griswold, Abel Eigege, Emmanuel C Emukah, Jayden Pace Gallagher, Jenna Coalson, Lindsay Rakers, Bulus Mancha, Okocha Ndudi, Paul Ugbadamu, Philomena Dikedi, Happiness Poko, Jacob Danboyi, Philemon Dagwa, Vincent Anighoro, Christiana Davou Gwong, Esther Otabor, Goodluck James Amayat, Regina Ese Unukopia, Emmanuel S Miri, Gregory S Noland
In Nigeria, mass drug administration (MDA) for schistosomiasis (SCH) and soil-transmitted helminthiasis (STH) has often been coordinated with other programs that receive greater external funding. As these programs reach stop MDA milestones, SCH and STH programs will likely need to transition implementation, or "mainstream," to domestic support. A mixed-methods study was conducted in four districts before (2021) and after (2022) mainstreaming to evaluate its impact on MDA coverage. Household surveys were done in 30 villages per district pre- and post-mainstreaming...
April 9, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38593791/a-community-health-worker-day-in-rural-chiapas-mexico-in-a-nutshell
#3
JOURNAL ARTICLE
Zeus Aranda
No abstract text is available yet for this article.
April 9, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38593790/antibody-seroprevalence-to-spotted-fever-group-rickettsiae-in-miraflores-colombia-a-cross-sectional-study-in-humans-and-dogs
#4
JOURNAL ARTICLE
Lídia Gual-Gonzalez, Omar Cantillo-Barraza, Myriam E Torres, Juan C Quintero-Vélez, Manuel Medina, Stella C W Self, Melissa S Nolan
Tick-borne disease burdens are increasing globally, impacting mostly rural and vulnerable communities. Among the most important emerging tick-borne pathogens are the Rickettsia species within the spotted fever group (SFGR) because of their genetic diversity and high lethality rate. Colombia is highly affected by SFGR despite not being reportable diseases; thus, research and clinical management are neglected. Although some departments have demonstrated high seroprevalence rates, in others, such as Boyacá Department, seroprevalence is unknown...
April 9, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38593789/the-2023-dengue-outbreak-in-bangladesh-exploring-the-epidemiology-in-hospitalized-patients
#5
JOURNAL ARTICLE
Urby Saraf Anika, Muna Islam, Fatema E Nur Mou, Mrinal Saha, Aparna Deb, Rubaiya Rahman Tui, Joarder Rakeen Manzoor, Afroza Jesmin, Ayesha Martuja, Jannatul Fardous, Mohiuddin Sharif, Md Abdur Rafi, Mohammad Jahid Hasan
For the past two decades, Bangladesh has faced recurrent dengue outbreaks, with the most recent occurring in 2023. We investigated the socioeconomic, clinical, and laboratory aspects of patients diagnosed with dengue during this outbreak. This observational study was conducted from July to September 2023 at Dhaka Medical College Hospital and Chittagong Medical College Hospital, and included 450 confirmed cases of dengue. Sociodemographic information was collected via face-to-face interviews, clinical examinations, and laboratory testing, which was done within 24 hours of admission...
April 9, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38593788/risk-factor-analysis-of-cutaneous-leishmaniasis-in-sri-lanka-through-a-nationwide-survey
#6
JOURNAL ARTICLE
Rajika Dewasurendra, Nilakshi Samaranayake, Hermali Silva, Nuwani Manamperi, Upul Senerath, Sanath Senanayake, Nissanka de Silva, Panduka Karunanayake, Guofa Zhou, Nadira Karunaweera
Leishmaniasis in Sri Lanka was first reported in the early 1990s. Cutaneous leishmaniasis (CL) cases have markedly increased in recent years, demanding due attention from health authorities. The spatial distribution of CL is not homogeneous. This case-control study investigated factors that may contribute to this heterogeneous distribution through a nationwide study. Information on sociodemographic, economic, and environmental characteristics was collected from study participants (cases, n = 303; controls, n = 2,762)...
April 9, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38593787/associations-between-covid-19-and-glucose-6-phosphate-dehydrogenase-activity-in-brazil
#7
JOURNAL ARTICLE
Maria Gabriela de Almeida Rodrigues, Wuelton Marcelo Monteiro, Gisely Cardoso de Melo, Ádila Liliane Barros Dias, Marco Aurélio Sartim, Mariana Simão Xavier, Rebeca Linhares Abreu Netto, Fernando Fonseca Almeida, Djane Clarys Baía-da-Silva, José Diego Brito-Sousa, Marcus Vinicius Guimarães de Lacerda, Vanderson de Souza Sampaio
Glucose-6 phosphate dehydrogenase deficiency (G6PDd) was suggested as a risk factor for severe disease in patients with COVID-19. We evaluated clinical outcomes and glucose-6 phosphate dehydrogenase (G6PD) activity during and after illness in patients with COVID-19. This prospective cohort study included adult participants (≥ 18 years old) who had clinical and/or radiological COVID-19 findings or positive reverse transcription-polymerase chain reaction results. Epidemiological and clinical data were extracted from electronic medical records...
April 9, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38593786/performance-assessment-of-treponemal-and-nontreponemal-tests-for-the-diagnosis-of-acquired-syphilis
#8
JOURNAL ARTICLE
Ângelo Antônio Oliveira Silva, Ayla Araújo Lima, Larissa de Carvalho Medrado Vasconcelos, Rosângela Andrade de Almeida, Natália Erdens Maron de Freitas, Fernanda Lopes Habib, Talita Andrade Oliva, Miralba Freire de Carvalho Ribeiro da Silva, Isadora Cristina de Siqueira, Fred Luciano Neves Santos
There are a variety of nontreponemal test (NTT) and treponemal test (TT) kits for the serologic diagnosis of syphilis. Because of the complexity of the infection (multiple clinical stages) and the different antigens used in these kits, a systematic evaluation of the accuracy of the currently available commercial tests is warranted. Our objective was to evaluate the performance of commercially available tests for the diagnosis of syphilis infection. In this study, we analyzed one NTT (Venereal Disease Research Laboratory [VDRL] test, Wiener Laboratories, Rosario, Argentina) and two TTs (fluorescent treponemal antibody absorption [FTA-ABS] test, Euroimmun, Lübeck, Germany, and syphilis recombinant ELISA v...
April 9, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38579704/cross-talk-between-micrornas-and-dengue-virus
#9
JOURNAL ARTICLE
Nur Omar Macha, Thamil Vaani Komarasamy, Sarahani Harun, Nur Amelia Azreen Adnan, Sharifah Syed Hassan, Vinod R M T Balasubramaniam
Dengue fever (DF) is an endemic infectious tropical disease and is rapidly becoming a global problem. Dengue fever is caused by one of the four dengue virus (DENV) serotypes and is spread by the female Aedes mosquito. Clinical manifestations of DF may range from asymptomatic to life-threatening severe illness with conditions of hemorrhagic fever and shock. Early and precise diagnosis is vital to avoid mortality from DF. A different approach is required to combat DF because of the challenges with the vaccines currently available, which are nonspecific; each is capable of causing cross-reaction and disease-enhancing antibody responses against the residual serotypes...
April 2, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38579703/potential-impact-of-a-diagnostic-test-for-detecting-prepatent-guinea-worm-infections-in-dogs
#10
JOURNAL ARTICLE
Hannah Smalley, Pinar Keskinocak, Julie Swann, Christopher Hanna, Adam Weiss
Chad has seen a considerable reduction in cases of Guinea worm disease (or dracunculiasis) in domestic dogs in recent years. Tethering of dogs and application of Abate® larvicide to water sources appear to have contributed to this progress, but with 767 reported dog cases in 2021, accelerating elimination of the disease in Chad may require additional tools. We investigate the potential benefits of a hypothetical diagnostic test that could be capable of detecting prepatent infections in dogs. We adapt an agent-based simulation model for forecasting the impact of interventions on guinea worm disease in dogs to examine the interaction of multiple test factors including test accuracy, when the test can detect infection, dog selection, and dog-owner compliance with tethering recommendations...
April 2, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38579702/malaria-slide-bank-to-strengthen-and-improve-the-quality-of-malaria-diagnosis-a-national-slide-repository-in-india
#11
JOURNAL ARTICLE
Shrikant Nema, Bina Srivastava, Naseem Ahmad, Supriya Sharma, Anup R Anvikar, Manju Rahi, Amit Sharma, Praveen Kumar Bharti, Nitika Nitika
Malaria elimination is one of the top health care priorities in India, necessitating accessible and accurate diagnosis for effective treatment. A malaria slide bank in India is a collection of quality-controlled malaria-positive and -negative slides and is considered a vital asset for quality diagnosis. The collection of blood samples, preparation of blood smears, staining, quality control, molecular characterizations, and slide validation were carried out according to standard operating procedures in accordance with the WHO reference laboratory...
April 2, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38579701/unusual-iliopsoas-abscess-due-to-salmonella-typhi
#12
JOURNAL ARTICLE
Harpreet Singh, Deba Prasad Dhibhar, Suresh Selvam, Vishal Kumar, Vikas Suri, Ashish Bhalla
No abstract text is available yet for this article.
April 2, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38579700/identification-of-dominant-leptospira-serogroups-among-leptospirosis-cases-and-their-clinical-outcomes-a-prospective-hospital-based-study-in-mangaluru-india
#13
JOURNAL ARTICLE
Gillaine Vail Pinto, Kuppusamy Senthilkumar, Praveen Rai, Shama Prakash Kabekkodu, Indrani Karunasagar, Ballamoole Krishna Kumar
Leptospirosis is a reemerging zoonotic disease of worldwide significance, endemic to the southern region of India, with clinical manifestations similar to other febrile illnesses; hence, it is often misdiagnosed and underreported. Inadequate information about the disease burden and the regional circulating serogroups contributes to its neglected disease status. This study aimed to identify the infecting Leptospira serogroup in the coastal region of Mangaluru and study the clinical symptoms and outcome among leptospirosis patients...
April 2, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38579699/enteric-fever-associated-hemophagocytic-lymphohistiocytosis-a-systematic-review-of-clinical-characteristics-and-outcomes
#14
JOURNAL ARTICLE
Durga Shankar Meena, Akhilesh Kumar, Deepak Kumar, Gopal Krishana Bohra, Abhishek Purohit
Enteric fever is a major contributor to rising health care costs in developing countries. Associated disease-related complications and drug resistance further compound this problem. Hemophagocytic lymphohistiocytosis (HLH) is an uncommon complication of enteric fever with high morbidity and mortality. This systematic review aimed to evaluate the clinical characteristics and treatment outcomes in enteric fever-associated HLH syndrome. We searched major electronic databases (PubMed, Google Scholar, and Scopus) to identify the cases of enteric fever associated with HLH from inception until June 2023...
April 2, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38579698/high-efficacy-of-ivermectin-for-strongyloidiasis-treatment
#15
JOURNAL ARTICLE
Chatchawan Sengthong, Somchai Pinlaor, Manachai Yingklang, Ornuma Haonon, Chanakan Jantawong, Porntip Pinlaor, Paiboon Sithithaworn, Nuttanan Hongsrichan
Infection with Strongyloides stercoralis is often asymptomatic but can be life-threatening in immunocompromised patients, which can be prevented by ivermectin (IVM) treatment. The efficacy of IVM has been reported to have lessened over time in some regions as a consequence of prolonged use and mass treatment campaigns. Ivermectin has been used in Thailand for more than a decade; therefore, we investigated the efficacy of a single dose (200 μg/kg) of IVM against in asymptomatic strongyloidiasis in northeastern Thailand...
April 2, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38579697/systematic-review-of-impacts-of-educational-interventions-to-control-breeding-sites-of-aedes-aegypti-and-aedes-albopictus-mosquitoes
#16
JOURNAL ARTICLE
Carola Soria, Walter Ricardo Almirón, Anna M Stewart-Ibarra, Liliana Beatriz Crocco
Community participation is a critical element in the management of Aedes aegypti and Aedes albopictus breeding sites. Many educational interventions have been conducted to encourage prevention and elimination of breeding sites among different community actors, such as government-run programs for vector surveillance aimed at preventing and eliminating breeding sites at the household level within a community. Getting people involved in prevention and elimination of vector breeding sites in their communities requires communication and social mobilization strategies to promote and reinforce those prevention actions that, in turn, should be effective from the entomological standpoint...
April 2, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38579695/costing-of-a-combination-intervention-kyaterekera-addressing-sexual-risk-taking-behaviors-among-vulnerable-women-in-southern-uganda
#17
JOURNAL ARTICLE
Yesim Tozan, Joshua Kiyingi, Sooyoung Kim, Josephine Nabayinda, Flavia Namuwonge, Edward Nsubuga, Fatuma Nakabuye, Ozge Bahar Sensoy, Proscovia Nabunya, Larissa Jennings Mayo-Wilson, Mary M McKay, Susan S Witte, Fred M Ssewamala
In Uganda, women engaged in sex work (WESW) are a marginalized population at the intersection of multiple vulnerabilities. The Kyaterekera intervention is targeted at WESW in Rakai and the greater Masaka regions in Uganda and combines a traditional HIV risk-reduction approach with a savings-led economic empowerment intervention and financial literacy training. We estimated the economic costs of the Kyaterekera intervention from a program provider perspective using a prospective activity-based micro-costing method...
April 2, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38574555/case-report-profound-anemia-in-a-2-year-old-boy-associated-with-a-leech-in-the-oropharynx
#18
Jerome Koleski, Amos Kipngetich Kurgat, Emilie Tindal, Jenna Haugen
A 2-year-old boy presented to Kapsowar Mission Hospital in Kenya with a history of general tiredness associated with mild, unilateral epistaxis and one episode of hematemesis. On admission, he had a hemoglobin value of 3.5 g/dL, with a white cell count of 20.6 × 109/L. The child was examined by the physician on call, with no source of bleeding found. Later that day, after a local physician noted that the presentation could be due to an unrecognized leech infestation, a deep examination of the oropharynx was performed with a laryngoscope and revealed a leech attached deep in the oropharynx...
April 2, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38574550/systematic-review-and-geospatial-modeling-of-molecular-markers-of-resistance-to-artemisinins-and-sulfadoxine-pyrimethamine-in-plasmodium-falciparum-in-india
#19
JOURNAL ARTICLE
Minu Nain, Mehul Dhorda, Jennifer A Flegg, Apoorv Gupta, Lucinda E Harrison, Sauman Singh-Phulgenda, Sabina D Otienoburu, Eli Harriss, Praveen K Bharti, Beauty Behera, Manju Rahi, Philippe J Guerin, Amit Sharma
Surveillance for genetic markers of resistance can provide valuable information on the likely efficacy of antimalarials but needs to be targeted to ensure optimal use of resources. We conducted a systematic search and review of publications in seven databases to compile resistance marker data from studies in India. The sample collection from the studies identified from this search was conducted between 1994 and 2020, and these studies were published between 1994 and 2022. In all, Plasmodium falciparum Kelch13 (PfK13), P...
April 2, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38574549/perspectives-on-the-performance-of-the-ethiopian-vaccine-supply-chain-and-logistics-system-after-the-last-mile-delivery-initiative-a-phenomenological-study
#20
JOURNAL ARTICLE
Samson Gebremedhin, Fisseha Shiferie, Dawit A Tsegaye, Wondwossen A Alemayehu, Tamiru Wondie, Solomon Zeleke, Belete Alebachew, Jen Donofrio, Frank DelPizzo, Kidist Belete, Gashaw Andarge Biks
Uninterrupted availability of vaccines requires a robust vaccine supply chain and logistics system (VSCLS). With special focus on remote and underserved settings, we assessed the reach and bottlenecks of the Ethiopian VSCLS after the initiation of the last mile transition. We explored the perspectives of key stakeholders using a qualitative phenomenological study. More than 300 in-depth interviews and 22 focus group discussions were conducted. The study was sequentially implemented over two phases to understand the bottlenecks at national and regional (Phase I) and lower (Phase II) levels...
April 2, 2024: American Journal of Tropical Medicine and Hygiene
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