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American Journal of Respiratory and Critical Care Medicine

https://read.qxmd.com/read/33835905/update-in-covid-19
#1
Sanjay H Chotirmall, Lindsay M Leither, Başak Çoruh, Louisa L Y Chan, Anthony M Joudi, Samuel M Brown, Benjamin D Singer, Nitin Seam
No abstract text is available yet for this article.
April 9, 2021: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/33835902/opioid-use-increases-the-risk-of-delirium-in-critically-ill-adults-independently-of-pain
#2
Matthew S Duprey, Sandra M A Dijkstra-Kersten, Irene J Zaal, Becky A Briesacher, Jane S Saczynski, John L Griffith, John W Devlin, Arjen J C Slooter
RATIONALE: It is unclear whether opioid use increases the risk of ICU delirium. Prior studies have not accounted for confounding including daily severity of illness, pain and competing events that may preclude delirium detection. OBJECTIVES: To evaluate the association between ICU opioid exposure, opioid dose, and delirium occurrence. METHODS: In consecutive adults admitted >24 hours to the ICU, daily mental status was classified as awake without delirium, delirium, or unarousable...
April 9, 2021: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/33835901/are-adults-with-copd-vulnerable-to-air-pollution-and-cardiovascular-risk
#3
C Arden Pope Iii
No abstract text is available yet for this article.
April 9, 2021: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/33835899/update-in-interstitial-lung-disease-2020
#4
Anna J Podolanczuk, Alyson W Wong, Shigeki Saito, Joseph A Lasky, Christopher J Ryerson, Oliver Eickelberg
No abstract text is available yet for this article.
April 9, 2021: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/33835896/overnight-oximetry-derived-pulse-rate-variability-predicts-stroke-risk-in-patients-with-obstructive-sleep-apnea
#5
AbdelKebir Sabil, Chloé Gervès-Pinquié, Margaux Blanchard, Mathieu Feuilloy, Wojciech Trzepizur, François Goupil, Thierry Pigeanne, Emmanuel Oger, Jean-Marc Girault, Frédéric Gagnadoux
No abstract text is available yet for this article.
April 9, 2021: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/33831329/exposing-pre-copd-when-physiology-matters
#6
J Alberto Neder, Juan Pablo de-Torres, Denis E O'Donnell
No abstract text is available yet for this article.
April 8, 2021: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/33831326/pre-copd-towards-the-limits-of-the-spirometric-funnel
#7
Emiel F M Wouters
No abstract text is available yet for this article.
April 8, 2021: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/33831325/asthma-with-a-smoking-history-and-pre-copd
#8
Neil C Thomson
No abstract text is available yet for this article.
April 8, 2021: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/33831319/reply-to-thomson-to-neder-et-al-and-to-wouters
#9
MeiLan K Han, Alvar Agusti, Bartolome R Celli, Gerard J Criner, David M G Halpin, Nicolas Roche, Alberto Papi, Robert A Stockley, Jadwiga Wedzicha, Claus F Vogelmeier
No abstract text is available yet for this article.
April 8, 2021: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/33826879/the-site-of-airway-collapse-in-sleep-apnea-its-associations-with-disease-severity-and-obesity-and-implications-for-mechanical-interventions
#10
Chung Man Sung, Shi Nee Tan, Min-Ho Shin, Jongho Lee, Hong Chan Kim, Sang Chul Lim, Hyung Chae Yang
No abstract text is available yet for this article.
April 7, 2021: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/33826872/cleaving-the-acute-respiratory-distress-syndrome-into-treatable-traits-a-role-for-caspase-1
#11
Lieuwe Dj Bos, Julie A Bastarache
No abstract text is available yet for this article.
April 7, 2021: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/33826869/is-glycemic-control-the-secret-to-tuberculosis-control
#12
Sophie Huddart, Rada M Savic, Adithya Cattamanchi
No abstract text is available yet for this article.
April 7, 2021: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/33823122/long-term-outcomes-in-intensive-care-unit-patients-with-delirium-a-population-based-cohort-study
#13
Kirsten M Fiest, Andrea Soo, Chel Hee Lee, Daniel J Niven, E Wesley Ely, Christopher J Doig, Henry T Stelfox
RATIONALE: Delirium is common in the intensive care unit (ICU) and portends worse ICU and hospital outcomes. The effect of delirium in the ICU on post-hospital discharge mortality and health resource utilization is less well known. OBJECTIVES: To estimate mortality and health resource utilization 2.5-years post-hospital discharge in critically ill patients admitted to ICU. METHODS: Population-based, propensity-score matched, retrospective cohort study of adult patients admitted to one of fourteen medical-surgical ICUs from January 1, 2014 to June 30, 2016...
April 6, 2021: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/33823118/ecmo-for-covid-19-associated-severe-ards-in-chile-a-nationwide-incidence-and-cohort-study
#14
Rodrigo A Diaz, Jerónimo Graf, José M Zambrano, Carolina Ruiz, Juan A Espinoza, Sebastian I Bravo, Pablo A Salazar, Juan C Bahamondes, Luis B Castillo, Abraham Ij Gajardo, Andrés Kursbaum, Leonila L Ferreira, Josefa Valenzuela, Roberto E Castillo, Rodrigo A Pérez-Araos, Marcela Bravo, Andrés F Aquevedo, Mauricio G González, Rodrigo Pereira, Leandro Ortega, César Santis, Paula A Fernández, Vilma Cortés, Rodrigo A Cornejo
RATIONALE: The role and needs of extracorporeal membrane oxygenation (ECMO) at a population-level during the COVID-19 pandemic have not been completely established. OBJECTIVES: To identify the cumulative incidence for ECMO use in the first pandemic wave and to describe the Nationwide Chilean cohort of ECMO-supported COVID-19 patients. METHODS: We conducted a population-based study from March 3 to August 31, 2020, using linked data from National agencies...
April 6, 2021: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/33823116/machine-learning-for-early-lung-cancer-identification-using-routine-clinical-and-laboratory-data
#15
Michael K Gould, Brian Z Huang, Martin C Tammemagi, Yaron Kinar, Ron Shiff
RATIONALE: Most lung cancers are diagnosed at an advanced stage. Pre-symptomatic identification of high-risk individuals can prompt earlier intervention and improve long-term outcomes. OBJECTIVE: To develop a model to predict a future diagnosis of lung cancer based on routine clinical and laboratory data, using machine-learning. METHODS: We assembled 6,505 non-small cell lung cancer (NSCLC) cases and 189,597 contemporaneous controls and compared the accuracy of a novel machine-learning model to a modified version of the well-validated PLCOm2012 risk model, using the area under the receiver operating characteristic curve (AUC), sensitivity and diagnostic odds ratio (OR) as measures of model performance...
April 6, 2021: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/33798036/mortality-from-pulmonary-hypertension-in-the-pediatric-cardiac-intensive-care-unit
#16
Emily Morell, Micheal Gaies, Jeffrey R Fineman, John Charpie, Rohit Rao, Jun Sasaki, Wenying Zhang, Garrett Reichle, Mousumi Banerjee, Sarah Tabbutt
RATIONALE: Patients with pulmonary hypertension admitted to pediatric cardiac intensive care units are at high risk of mortality. OBJECTIVES: We identified factors associated with mortality in cardiac critical care admissions with pulmonary hypertension. METHODS: We evaluated pulmonary hypertension medical admissions to Pediatric Cardiac Critical Care Consortium (PC4) institutions over five years. Pulmonary hypertension was standardly defined in the clinical registry by diagnosis and/or receipt of intensive care-level pulmonary vasodilator therapy...
April 2, 2021: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/33798018/within-city-variation-in-reactive-oxygen-species-from-fine-particle-air-pollution-and-covid-19
#17
David M Stieb, Greg J Evans, Teresa M To, Pascale S J Lakey, Manabu Shiraiwa, Marianne Hatzopoulou, Laura Minet, Jeffrey R Brook, Richard T Burnett, Scott A Weichenthal
RATIONALE: Evidence linking outdoor air pollution with COVID-19 incidence and mortality is largely based on ecological comparisons between regions that may differ in factors such as access to testing and control measures that may not be independent of air pollution concentrations. Moreover, studies have yet to focus on key mechanisms of air pollution toxicity such as oxidative stress. OBJECTIVES: To conduct a within-city analysis of spatial variations in COVID-19 incidence and the estimated generation of reactive oxygen species (ROS) in lung lining fluid attributable to fine particulate matter (PM2...
April 2, 2021: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/33794131/protocolized-post-extubation-respiratory-support-to-prevent-reintubation-a-randomized-clinical-trial
#18
Jonathan D Casey, Erin M Vaughan, Bradley D Lloyd, Peter A Billas, Karen E Jackson, Eric J Hall, Alexandra H Toporek, Kevin G Buell, Ryan M Brown, Roger K Richardson, J Craig Rooks, Reagan B Buie, Li Wang, Christopher J Lindsell, E Wesley Ely, Wesley H Self, Gordon R Bernard, Todd W Rice, Matthew W Semler
RATIONALE: Respiratory support (non-invasive ventilation or high flow nasal cannula) applied at the time of extubation has been reported to reduce reintubation rates, but concerns regarding effectiveness have limited uptake into practice. OBJECTIVES: To determine if providing post-extubation respiratory support to all patients undergoing extubation in a medical ICU would decrease the incidence of reintubation. METHODS: We conducted a pragmatic, two-armed, cluster-crossover trial of adults undergoing extubation from invasive mechanical ventilation between October 1, 2017 and March 31, 2019 in the medical intensive care unit of an academic medical center...
April 1, 2021: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/33789070/surrogate-markers-for-pulmonary-hypertension-may-inform-prognosis-in-lung-cancer
#19
Lindsay M Forbes, Sue Gu, David B Badesch
No abstract text is available yet for this article.
March 31, 2021: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/33789069/a-proposed-revision-of-the-stepwise-treatment-algorithm-in-asthma
#20
Richard Beasley, Pepa Bruce, Lee Hatter, Irene Braithwaite, Alex Semprini, Ciléin Kearns, Mark Weatherall, Ian D Pavord
No abstract text is available yet for this article.
March 31, 2021: American Journal of Respiratory and Critical Care Medicine
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