journal
https://read.qxmd.com/read/38763498/bilateral-corneal-and-conjunctival-melanosis
#21
JOURNAL ARTICLE
Adam Wylęgała, Jacek Pająk, Edward Wylęgała
No abstract text is available yet for this article.
May 17, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38763497/an-evidence-based-approach-to-diagnosing-patients-presenting-with-orbital-inflammatory-syndromes-an-american-ophthalmological-society-thesis
#22
JOURNAL ARTICLE
Michael K Yoon, Jonathan E Lu
PURPOSE: The initial management of patients presenting with orbital inflammatory syndromes (OIS) varies - with some pursuing a diagnostic workup while others treat without any testing. The evidence behind this rationale is limited. A review of patients with orbital inflammation is performed with analysis of diagnostic testing to develop a workflow for such patients. DESIGN: A retrospective review of patients presenting with acute orbital inflammation at a single institution from 2011 - 2020 was conducted...
May 17, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38762092/choroidal-nevi-in-children-size-growth-and-topographic-distribution
#23
JOURNAL ARTICLE
Yağmur Seda Yeşiltaş, Nakul Singh, Zackery Oakey, Jacquelyn Wrenn, Arun D Singh
PURPOSE: To explore size, growth, and topographic distribution of choroidal nevi in children to gain insights into choroidal nevogenesis. DESIGN: Retrospective consecutive case series using pediatric clinic - and population - study data, comparing to adult data. METHODS: Clinical data from Cole Eye Institute (CEI) database (December 2005-January 2023) was derived from a retrospective consecutive case series of 20 children (< 20 years) with choroidal nevi...
May 16, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38762091/association-between-cardiovascular-health-and-retinopathy-in-us-adults-from-nhanes-2005-2008
#24
JOURNAL ARTICLE
Xiangliang Liu, Yu Chang, Yuguang Li, Yingrui Liu, Naifei Chen, Jiuwei Cui
PURPOSE: Investigating the relationship between cardiovascular health (CVH) and retinopathy in the adult population of the United States. DESIGN: The cross-sectional study Methods: The study utilized samples, including the diabetes population, from the National Health and Nutrition Examination Survey (NHANES) conducted between 2005 and 2008 (N= 4,249), to assess cardiovascular health (CVH) using the Life's Essential 8 (LE8) assessment. Retinopathy are determined through imaging assessment by professionals independently grading fundus photographs...
May 16, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38754801/diagnostic-accuracy-of-optic-nerve-head-and-macula-oct-parameters-for-detecting-glaucoma-in-eyes-with-and-without-high-axial-myopia
#25
JOURNAL ARTICLE
Jasmin Rezapour, Evan Walker, Akram Belghith, Christopher Bowd, Massimo A Fazio, Anuwat Jiravarnsirikul, Leslie Hyman, Jost B Jonas, Robert N Weinreb, Linda M Zangwill
PURPOSE: To characterize structural differences and assess the diagnostic accuracy of optic nerve head (ONH) and macula optical coherence tomography (OCT) parameters to detect glaucoma in eyes with and without high axial myopia. DESIGN: Cross-sectional study METHODS: 368 glaucoma and 411 healthy eyes with no axial myopia, 393 glaucoma and 271 healthy eyes with mild axial myopia and 124 glaucoma and 85 healthy eyes with high axial myopia were included. Global and sectoral peripapillary retinal nerve fiber layer thickness (pRNFLT), Bruch's membrane opening minimum rim width (BMO-MRW), ganglion cell inner plexiform layer thickness (GCIPLT), and macula RNFLT (mRNFLT) were compared and the diagnostic accuracy for glaucoma detection was evaluated using adjusted area under the receiver operating characteristic curve (AUC)...
May 14, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38754800/arterial-stiffness-and-incident-glaucoma-a-large-population-based-cohort-study
#26
JOURNAL ARTICLE
Angela L Beros, John D Sluyter, Alun D Hughes, Bernhard Hametner, Siegfried Wassertheurer, Prof Robert Kr Scragg
PURPOSE: To investigate whether arterial stiffness, assessed oscillometrically, is associated with incident glaucoma in the Vitamin D Assessment (ViDA) Study cohort, aged 50-84 years. DESIGN: Prospective, population-based cohort study METHODS: : Arterial stiffness was assessed in 4713 participants without known glaucoma (mean±SD age = 66±8 years) from 5 April 2011 to 6 November 2012 by way of aortic PWV (aPWV), estimated carotid-femoral PWV (ePWV) and aortic PP (aPP)...
May 14, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38740237/polygenic-prediction-of-keratoconus-and-its-measures-cross-sectional-and-longitudinal-analyses-in-community-based-young-adults
#27
JOURNAL ARTICLE
Samantha Sze-Yee Lee, Santiago Diaz-Torres, Weixiong He, Seyhan Yazar, Elsie Chan, Elaine W Chong, Puya Gharahkhani, Stuart MacGregor, Gareth Lingham, David A Mackey
AIM: This study evaluates the performance of a multitrait polygenic risk score (PRS) in an independent cohort to predict incident or progression of keratoconus. DESIGN: Prospective cross-sectional and cohort study METHODS: Setting: Single-centre; Study population: 1,478 community-based young adults (18-30 years; 51% female), including 609 (52% female) who returned for an 8-year follow-up; Observation procedures: Scheimpflug imaging (Pentacam, Oculus), genotyping and development of a multitrait PRS previously validated to predict keratoconus in older adults...
May 11, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38735449/recurrence-characteristics-on-optical-coherence-tomography-and-treatments-of-reis-b%C3%A3-cklers-corneal-dystrophy-after-phototherapeutic-keratectomy-or-penetrating-keratoplasty-recurrence-characteristics-and-treatments-of-rbcd
#28
JOURNAL ARTICLE
Dewei Li, Le Tian, Xiaochuan Wang, Feifei Zhang, Ting Liu, Yanling Dong, Ping Lin, Dongfang Li, Dapeng Sun, Min Chen
PURPOSE: To evaluate the recurrence characteristics on optical coherence tomography and clinical outcomes after phototherapeutic keratectomy (PTK) or penetrating keratoplasty (PKP) in patients with Reis-Bücklers corneal dystrophy (RBCD). DESIGN: Retrospective interventional case series. METHODS: Seventeen patients with RBCD (31 eyes, including six surgery-naïve eyes and 25 surgical eyes) received 44 surgical interventions from 1996 through 2022...
May 10, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38734527/corrigendum-to-yilmaz-yc-hayat-sc-ipek-sc-analysis-of-corneal-and-lens-densitometry-changes-in-patients-with-type-1-diabetes-mellitus-am-j-ophthalmol-2023-oct-254-23-30
#29
Yusuf Cem Yilmaz, Serife Ciloglu Hayat, Sefik Can Ipek
No abstract text is available yet for this article.
May 10, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38729865/corrigendum-to-wu-w-kang-x-fang-w-et-al-clinical-diagnostic-and-treatment-characteristics-of-orbital-liposarcoma-am-j-ophthalmol-2024-262-134-140
#30
Wei Wu, Xin Kang, Wei Fang, Yueyue Li, Rui Ma, Mingshen Ma, Yan Hei, Qi Wang, Xiaoyi Wang, Xuetao Mu, Shuixi Zhao, Xinji Yang
No abstract text is available yet for this article.
May 9, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38719133/pathogenesis-of-central-serous-chorioretinopathy-and-the-link-between-choroidal-hyperpermeability-and-rpe-pump-reversal
#31
JOURNAL ARTICLE
Federica Fossataro, Claudia Fossataro, Neda Abraham, Yousef Fouad, Sarah Mrejen, Anna Cs Tan, Shilo Voichaski, David Sarraf
PURPOSE: To describe 6 cases of acute central serous chorioretinopathy (CSCR) and the response to laser treatment, focusing on the underlying pathogenic mechanism. METHODS: Multimodal imaging from 6 eyes of 6 patients with acute and recurrent CSCR were reviewed including fundus autofluorescence (FAF), fluorescein angiography (FA), indocyanine green angiography (ICGA) and optical coherence tomography (OCT) at baseline and after laser therapy. RESULTS: In 3 out of the 6 cases with acute CSCR, the hyporeflective lucency sign was identified with cross sectional and en face OCT and co-localized with an intense active inkblot retinal pigment epithelium (RPE) leak on FA...
May 6, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38719132/repeatability-and-agreement-of-4-biometers-measuring-corneal-astigmatism-in-eyes-with-irregular-corneal-astigmatism-component
#32
JOURNAL ARTICLE
Lan Wang, Xu Shao, Jin-Ling Fu, Jing-Jing Hu, Kai-Jing Zhou, Ran Li, A-Yong Yu
PURPOSE: To investigate the repeatability and agreement of corneal astigmatism measurements in eyes with irregular corneal astigmatism component (ICAC) using four devices: IOLMaster 700 biometer, Lenstar 900 biometer, iTrace, and Pentacam. DESIGN: Prospective cross-sectional reliability analysis. METHODS: Sixty-four eyes (52 patients) with ICAC were examined three times using the four devices. The eye with ICAC in this study is defined as the cornea has a certain degree of irregular astigmatism (asymmetric and/or skewed bowtie pattern of corneal topography according to corneal topography classification), accompanied with total corneal higher-order aberrations in the 4 mm zone of 0...
May 6, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38719131/correlation-between-blue-fundus-autofluorescence-and-sd-oct-measurements-of-geographic-atrophy-in-dry-age-related-macular-degeneration
#33
JOURNAL ARTICLE
Justis P Ehlers, Conor McConville, Sari Yordi, Hasan Cetin, Yavuz Cakir, Gagan Kalra, Reem Amine, Jon Whitney, Victoria Whitmore, Michelle Bonnay, Jamie Reese, Julie Clark, Liansheng Zhu, Don Luo, Glenn J Jaffe, Sunil K Srivastava
PURPOSE: To compare fundus autofluorescence (FAF) and spectral domain-optical coherence tomography (OCT) measurements of geographic atrophy (GA) area and to analyze lesion area changes measured by SD-OCT in GATHER1. DESIGN: An assessment reliability analysis using prospective, randomized, double-masked phase 2/3 clinical trial data. METHODS: GATHER1 examined the efficacy and safety of avacincaptad pegol (ACP) for GA treatment. A post hoc analysis was performed to identify correlations between FAF- and OCT-based measurements of GA...
May 6, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38710352/pediatric-and-adolescent-traumatic-macular-hole-a-systematic-review
#34
REVIEW
Youssef Ah Helmy, Ayman G ElNahry, Ola El Zein, Suzanne Charbaji, Yoshihiro Yonekawa, Hana A Mansour, Hashem Abu Serhan, Mutaz Al-Nawaflh, Maurizio Battaglia Parodi, Basil K Williams, Ahmad M Mansour
PURPOSE: The optimal management of pediatric traumatic macular holes (TMH) is unclear from lack of prospective randomized trials. The literature is divided into early (≤1month post-trauma), delayed (>1month) pars plana vitrectomy (PPV), and observation. Our aim is to find which group can achieve superior spectacle corrected visual acuity (VA), visual gain, and time for hole closure. DESIGN: Systematic Review. METHODS: This systematic review was registered with PROSPERO (ID:CRD42022383134)...
May 4, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38705553/association-of-retinal-thickness-at-month-1-post-treatment-with-later-thickness-and-visual-acuity-in-central-vein-occlusion
#35
JOURNAL ARTICLE
Ingrid U Scott, Neal L Oden, Michael S Ip, Paul C VanVeldhuisen, Barbara A Blodi
PURPOSE: To investigate the association of retinal thickness 1 month post-randomization (1 month after first study injection with aflibercept or bevacizumab) with later retinal thickness, visual acuity, and number of treatments in eyes with central or hemiretinal vein occlusion enrolled in the SCORE2 trial. DESIGN: Cohort study using data from a randomized multicenter clinical trial. METHODS: Analysis included 350 SCORE2 participants through 2 years of follow-up...
May 3, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38705552/causal-links-between-systemic-disorders-and-keratoconus-in-european-population
#36
JOURNAL ARTICLE
Xiaxue Chen, Lanlan Chen
PURPOSE: The objective of this study was to establish the presence of a causal linkage between prevalent systemic diseases and keratoconus (KC). DESIGN: Mendelian randomization (MR) analysis. METHODS: After an exhaustive screening process, genetic variants linked to various systemic diseases were identified as instrumental variables at the genome-wide significance level. Subsequently, MR analyses were conducted to elucidate their potential causal connection with KC (N = 26,742)...
May 3, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38705551/accuracy-of-toric-intraocular-lens-formulas-with-measured-posterior-corneal-astigmatism-of-different-orientations
#37
JOURNAL ARTICLE
Stephen Stewart, Tun Kuan Yeo, Salissou Moutari, Richard McNeely, Jonathan E Moore
PURPOSE: To assess whether the use of measured posterior corneal astigmatism (PCA) values improves the prediction accuracy of toric intraocular lens power formulas, compared to predicted PCA values, when the orientation of the steep axis of PCA is non-vertical. DESIGN: Retrospective observational cohort study METHODS: 418 eyes of 344 patients were included in the study. Prediction errors (PE) for postoperative refractive astigmatism at 4 weeks postoperatively were determined using vector analysis and compared for the following toric intraocular lens power formulas: Barrett Toric with predicted posterior corneal astigmatism (PPCA); Barrett Toric with measured posterior corneal astigmatism (MPCA); EVO Toric PPCA; EVO Toric MPCA; Holladay I with Abulafia-Koch regression...
May 3, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38703802/progression-or-aging-a-deep-learning-approach-for-distinguishing-glaucoma-progression-from-age-related-changes-in-oct-scans
#38
JOURNAL ARTICLE
Sayan Mandal, Alessandro A Jammal, Davina Malek, Felipe A Medeiros
PURPOSE: To develop deep learning (DL) algorithm to detect glaucoma progression using optical coherence tomography (OCT) images, in the absence of a reference standard. DESIGN: Retrospective cohort study. METHODS: Glaucomatous and healthy eyes with ≥5 reliable peripapillary OCT (Spectralis, Heidelberg Engineering) circle scans were included. A weakly supervised time-series learning model, called Noise Positive-Unlabeled (Noise-PU) DL was developed to classify whether sequences of OCT B-scans showed glaucoma progression...
May 2, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38703801/reduction-of-optic-disc-microvasculature-and-retinal-nerve-fiber-layer-thinning-in-patients-with-glaucoma
#39
JOURNAL ARTICLE
Min Hee Suh, Robert N Weinreb, Linda M Zangwill, Evan Walke
PURPOSE: To assess the relationship between the change of optic disc vessel density (ODVD) and retinal nerve fiber layer (RNFL) thinning in primary open-angle glaucoma (POAG) patients. DESIGN: Retrospective case series. METHODS: For 105 POAG patients, ≥ 5 consecutive optical coherence tomography (OCT) and OCT angiography (OCTA) images were obtained during ≥ 2 years of follow-up. Based on enface OCTA imaging, ODVD was calculated as the ratio of pixels occupied by vessels below the internal limiting membrane within the temporal area of the optic cup, and ODVD reduction was determined when there was a statistically significant negative slope (P < 0...
May 2, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38703800/accuracy-of-modern-intraocular-lens-formulas-in-highly-myopic-eyes-implanted-with-plate-haptic-intraocular-lenses
#40
JOURNAL ARTICLE
Er Mo, Zexin Chen, Ke Feng, Zehui Zhu, Jialin Xu, Chenyuan Zhu, Pingjun Chang, Jin Li, Yun-E Zhao
PURPOSE: To evaluate the predictive accuracy of modern intraocular lens (IOL) formulas and axial length (AL) adjusted traditional IOL formulas, including Wang-Koch and Cooke-modified AL (CMAL) method, in long eyes with plate-haptic IOLs, and to compare refractive prediction error variances with C-loop IOLs. DESIGN: Retrospective consecutive case series study. METHODS: Data from 391 eyes with Zeiss 509M and 302 eyes with Alcon SN6CWS implants in highly myopic patients, following cataract surgery from January 2019 to November 2023, were collected...
May 2, 2024: American Journal of Ophthalmology
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