Giuseppe Guglielmini, Emanuela Falcinelli, Elisa Piselli, Anna Maria Mezzasoma, Francesca Tondi, Luisa Alfonsi, Caterina De Luca, Valeria Fino, Alessandro Favilli, Sara Parrettini, Pietro Minuz, Elisabetta Torlone, Paolo Gresele, Sandro Gerli
OBJECTIVE: Gestational diabetes mellitus (GDM) is associated with obstetrical and long-term cardiovascular complications. While platelet hyperresponsiveness in type-2 diabetes mellitus has been well-characterized and shown to play a crucial role in cardiovascular complications, this aspect has been little studied in GDM. We aimed to evaluate platelet reactivity, in vivo platelet activation, and endothelial function in GDM compared with normal pregnancy. RESEARCH DESIGN AND METHODS: Prospective case-control study including 23 GDM and 23 healthy pregnant (HP) women studied at 26-28, 34-36 weeks of gestation and 8 weeks post-partum...
April 4, 2024: American Journal of Obstetrics and Gynecology