Mary S Anthony, Susan D Reed, Mary Anne Armstrong, Darios Getahun, Jennifer L Gatz, Catherine W Saltus, Xiaolei Zhou, Juliane Schoendorf, Debbie A Postlethwaite, Tina Raine-Bennett, Michael J Fassett, Jeffrey F Peipert, Mary E Ritchey, Laura E Ichikawa, Richard Lynen, Amy L Alabaster, Maqdooda Merchant, Vicki Y Chiu, Jiaxiao M Shi, Fagen Xie, Siu L Hui, Jinyi Wang, Shannon Hunter, Jennifer Bartsch, Ann-Kathrin Frenz, Giulia Chillemi, Theresa M Im, Harpreet S Takhar, Alex Asiimwe
BACKGROUND: Intrauterine devices (IUDs) are effective and safe, long-acting reversible contraceptives, but risk of uterine perforation occurs with an estimated incidence of 1-2 per 1,000 insertions. EURAS-IUD, a European prospective observational study that enrolled 61,448 participants (2006-2012), found that women breastfeeding at the time of device insertion or with the device inserted ≤36 weeks postpartum had higher risk of uterine perforation. APEX-IUD (Association of uterine Perforation and EXpulsion of IUD) is a Food and Drug Administration-mandated study designed to reflect current United States clinical practice...
January 15, 2021: American Journal of Obstetrics and Gynecology