journal
https://read.qxmd.com/read/36965003/resolving-the-aetiology-and-treatments-of-allergic-diseases
#1
EDITORIAL
Luo Zhang, Cezmi A Akdis
No abstract text is available yet for this article.
March 25, 2023: Allergy
https://read.qxmd.com/read/36961370/is-exposure-to-pollen-a-risk-factor-for-moderate-and-severe-asthma-exacerbations
#2
REVIEW
Isabella Annesi-Maesano, Lorenzo Cecchi, Biagioni Benedetta, Kian Fan Chung, Bernard Clot, Martine Collaud Coen, Gennaro D'Amato, Athanasios Damialis, Javier Dominguez-Ortega, Carmen Galàn, Stefanie Gilles, Stephen Holgate, Mohamed Jeebhay, Stelios Kazadzis, Nikolaos G Papadopoulos, Santiago Quirce, Joaquin Sastre, Fiona Tummon, Claudia Traidl-Hoffmann, Jolanta Walusiak-Skorupa, Pablo Alonso-Coello, Carlos Canelo-Aybar, Yahveth Cantero-Fortiz, David Rigau, Josefina Salazar, Francisca Verdugo-Paiva, Marek Jutel, Cezmi A Akdis, Ioana Agache
BACKGROUND: Limited number of studies have focused on the impact of pollen exposure on asthma. As a part of the EAACI Guidelines on Environment Science, this first systematic review on the relationship of pollen exposure to asthma exacerbations aimed to bridge this knowledge gap in view of implementing recommendations of prevention. METHODS: We searched electronic iPubMed, Embase, and Web of Science databases using a set of MeSH terms and related synonyms and identified 73 eligible studies that were included for systemic review...
March 24, 2023: Allergy
https://read.qxmd.com/read/36951669/disparities-and-inequalities-of-penicillin-allergy-in-the-asia-pacific-region
#3
LETTER
Philip H Li, Ruby Pawankar, Bernard Y H Thong, Hugo W F Mak, Grace Chan, Wen-Hung Chung, Juan Meng, Hye-Ryun Kang, Byung-Keun Kim, Rommel Crisenio M Lobo, Michaela Lucas, Pham Le Duy, Thushali Ranasinghe, Iris Rengganis, Ticha Rerkpattanapipat, Sonomjamts Munkhbayarlakh, Yi-Giien Tsai, Jiu-Yao Wang, Masao Yamaguchi, James Yun
No abstract text is available yet for this article.
March 23, 2023: Allergy
https://read.qxmd.com/read/36951658/anti-cd3-inhibits-circulatory-and-tissue-resident-memory-cd4-t-cells-that-drive-asthma-exacerbations-in-mice
#4
JOURNAL ARTICLE
Gurupreet S Sethi, Donald T Gracias, Rinkesh K Gupta, Daniel Carr, Haruka Miki, Ricardo Da Silva Antunes, Michael Croft
BACKGROUND: Exacerbations of asthma are thought to be strongly dependent on reactivation of allergen-induced lung tissue-resident and circulatory memory CD4 T cells. Strategies that broadly inhibit multiple T cell populations might then be useful to limit asthma. Accordingly, we tested whether targeting CD3 during exposure to inhaled allergen could prevent the accumulation of lung-localized effector memory CD4 T cells and block exacerbations of asthmatic inflammation. METHODS: House dust mite sensitized and repetitively challenged BL/6 mice were transiently treated therapeutically with F(ab')2 anti-CD3ε and memory T cell responses and lung inflammation were assessed...
March 23, 2023: Allergy
https://read.qxmd.com/read/36946297/atopic-dermatitis-correlation-of-distinct-risk-factors-with-age-of-onset-in-adulthood-compared-to-childhood
#5
JOURNAL ARTICLE
Laura Maintz, Marie-Therese Schmitz, Nadine Herrmann, Svenja Müller, Regina Havenith, Juliette Brauer, Claudio Rhyner, Anita Dreher, Eugen Bersuch, Danielle Fehr, Gertrud Hammel, Matthias Reiger, Daria Luschkova, Avidan Neumann, Claudia C V Lang, Ellen D Renner, Peter Schmid-Grendelmeier, Claudia Traidl-Hoffmann, Cezmi A Akdis, Roger Lauener, Marie-Charlotte Brüggen, Matthias Schmid, Thomas Bieber
BACKGROUND: Atopic dermatitis (AD) has long been regarded as a primarily pediatric disease. However, there is growing evidence for a high rate of adult-onset AD. We aimed to characterize factors associated with adult-onset versus (vs.) childhood-onset AD and controls. METHODS: We analyzed cross-sectional data of the CK-CARE-ProRaD cohorts Bonn, Augsburg, Davos, Zürich of 736 adult patients stratified by age of AD onset (childhood-onset <18 years: 76...
March 22, 2023: Allergy
https://read.qxmd.com/read/36946258/successful-usage-of-a-chatbot-to-standardize-and-automate-history-taking-in-hymenoptera-venom-allergy
#6
LETTER
Simon Schneider, Christine Gasteiger, Hannah Wecker, Jonas Höbenreich, Tilo Biedermann, Knut Brockow, Alexander Zink
No abstract text is available yet for this article.
March 22, 2023: Allergy
https://read.qxmd.com/read/36940306/trait-profiles-in-difficult-to-treat-asthma-clinical-impact-and-response-to-systematic-assessment
#7
JOURNAL ARTICLE
Tiffany Lin, Pham Jonathan, Eve Denton, Joy Lee, Fiona Hore-Lacy, Asger Sverrild, Stephanie Stojanovic, Tunn Ren Tay, Kavitha Garuna Murthee, Naghmeh Radhakrishna, Monique Dols, Janet Bondarenko, Janine Mahoney, Robyn E O'Hehir, Eli Dabscheck, Mark Hew
BACKGROUND: Multidisciplinary systematic assessment improves outcomes in difficult-to-treat asthma, but without clear response predictors. Using a treatable-traits framework, we stratified patients by trait profile, examining clinical impact and treatment responsiveness to systematic assessment. METHODS: We performed latent class analysis using 12 traits on difficult-to-treat asthma patients undergoing systematic assessment at our institution. We examined Asthma Control Questionnaire (ACQ-6) and Asthma Quality of Life Questionnaire (AQLQ) scores, FEV1 , exacerbation frequency, and maintenance oral corticosteroid (mOCS) dose, at baseline and following systematic assessment...
March 20, 2023: Allergy
https://read.qxmd.com/read/36934417/legends-of-allergy-gianni-marone
#8
Massimo Triggiani, Vincenzo Casolaro, Cristiana Stellato
No abstract text is available yet for this article.
March 19, 2023: Allergy
https://read.qxmd.com/read/36934403/dupilumab-associated-ocular-surface-disease-in-atopic-dermatitis-patients-clinical-characteristics-ophthalmic-treatment-response-and-conjunctival-goblet-cell-analysis
#9
JOURNAL ARTICLE
Roselie Achten, Judith Thijs, Marlot van der Wal, Chantal van Luijk, Marlies de Graaf, Daphne Bakker, Joke de Boer, Femke van Wijk, Marjolein de Bruin-Weller
BACKGROUND: Dupilumab-associated ocular surface disease (DAOSD) is frequently reported as side effect in atopic dermatitis (AD) patients. Therefore, the aim of this study was to investigate the frequency and severity of DAOSD, ophthalmic treatment response, and to learn more about the effect of dupilumab on conjunctival goblet cells (GC). METHODS: This prospective study included dupilumab-treated AD patients between February 2020 and June 2022 from the University Medical Centre Utrecht...
March 19, 2023: Allergy
https://read.qxmd.com/read/36934290/global-initiative-for-asthma-gina-30%C3%A2-years-of-promoting-evidence-based-asthma-care
#10
EDITORIAL
Arzu Yorgancıoğlu, Helen K Reddel
No abstract text is available yet for this article.
March 18, 2023: Allergy
https://read.qxmd.com/read/36929509/comparative-effectiveness-of-anti-il5-and-anti-ige-biologic-classes-in-patients-with-severe-asthma-eligible-for-both
#11
JOURNAL ARTICLE
Paul E Pfeffer, Nasloon Ali, Ruth Murray, Charlotte Ulrik, Trung N Tran, Jorge Maspero, Matthew Peters, George C Christoff, Mohsen Sadatsafavi, Carlos A Torres-Duque, Alan Altraja, Lauri Lehtimäki, Nikolaos G Papadopoulos, Sundeep Salvi, Richard W Costello, Breda Cushen, Enrico Heffler, Takashi Iwanaga, Mona Al-Ahmad, Désirée Larenas-Linnemann, Piotr Kuna, João A Fonseca, Riyad Al-Lehebi, Chin Kook Rhee, Luis Perez-de-Llano, Diahn-Warng Perng Steve, Bassam Mahboub, Eileen Wang, Celine Goh, Juntao Lyu, Anthony Newell, Marianna Alacqua, Andrey S Belevskiy, Mohit Bhutani, Leif Bjermer, Unnur Bjornsdottir, Arnaud Bourdin, Anna von Bulow, John Busby, Giorgio Walter Canonica, Borja G Cosio, Del Dorscheid, Mariana Muñoz-Esquerre, J Mark FitzGerald, Esther Garcia Gil, Peter G Gibson, Liam G Heaney, Mark Hew, Ole Hilberg, Flavia Hoyte, David J Jackson, Mariko Siyue Koh, Hsin-Kuo Ko Bruce, Jae Ha Lee, Sverre Lehmann, Cláudia Chaves Loureiro, Dóra Lúðvíksdóttir, Andrew N Menzies-Gow, Patrick Mitchell, Andriana I Papaioannou, Todor A Popov, Celeste M Porsbjerg, Laila Salameh, Concetta Sirena, Camille Taillé, Christian Taube, Yuji Tohda, Michael E Wechsler, David Price
BACKGROUND: Patients with severe asthma may present with characteristics representing overlapping phenotypes, making them eligible for more than one class of biologic. Our aim was to describe the profile of adult patients with severe asthma eligible for both anti-IgE and anti-IL5/5R and to compare the effectiveness of both classes of treatment in real life. METHODS: This was a prospective cohort study that included adult patients with severe asthma from 22 countries enrolled into the International Severe Asthma registry (ISAR) who were eligible for both anti-IgE and anti-IL5/5R...
March 17, 2023: Allergy
https://read.qxmd.com/read/36929486/severe-and-refractory-anaphylaxis-in-paediatric-intensive-care-unit
#12
LETTER
Guillaume Pouessel, Capucine Trochu, Flore Chagnon, Rémy Diesnis, Stéphane Leteurtre, Antoine Deschildre
No abstract text is available yet for this article.
March 17, 2023: Allergy
https://read.qxmd.com/read/36928862/microbes-antibodies-and-breastfeeding-as-the-trans-generational-axis-of-microbiota-maturation
#13
LETTER
Edyta Bulanda, Tomasz P Wypych
No abstract text is available yet for this article.
March 17, 2023: Allergy
https://read.qxmd.com/read/36929161/proinflammatory-polarization-of-monocytes-by-particulate-air-pollutants-is-mediated-by-induction-of-trained-immunity-in-pediatric-asthma
#14
JOURNAL ARTICLE
Hesam Movassagh, Mary Prunicki, Abhinav Kaushik, Xiaoying Zhou, Diane Dunham, Eric M Smith, Ziyuan He, German R Aleman Muench, Minyi Shi, Annika K Weimer, Shu Cao, Sandra Andorf, Amir Feizi, Michael P Snyder, Pejman Soroosh, Elizabeth D Mellins, Kari C Nadeau
BACKGROUND: The impact of exposure to air pollutants, such as fine particulate matter (PM), on the immune system and its consequences on pediatric asthma, are not well understood. We investigated whether ambient levels of fine PM with aerodynamic diameter ≤2.5 microns (PM2.5 ) are associated with alterations in circulating monocytes in children with or without asthma. METHODS: Monocyte phenotyping was performed by cytometry time-of-flight (CyTOF). Cytokines were measured using cytomtric bead array and Luminex assay...
March 16, 2023: Allergy
https://read.qxmd.com/read/36919650/prescribing-patterns-of-budesonide-formoterol-maintenance-and-reliever-therapy-in-patients-with-asthma-in-sweden
#15
LETTER
Christer Janson, Erik Melén, Sofie de Fine Licht, Gunilla Telg, Ekaterina Maslova, Trung N Tran, Filip Surmont, Fredrik Wiklund, Urban Olsson, Bright I Nwaru, Magnus Ekström
No abstract text is available yet for this article.
March 15, 2023: Allergy
https://read.qxmd.com/read/36916643/ph-sensing-shapes-immune-cell-function-the-role-of-gpr65-and-its-implications-for-allergic-disease
#16
Sabrina de Souza Ferreira, Marie Kaarup Bek, Christopher Andrew Tibbitt
No abstract text is available yet for this article.
March 14, 2023: Allergy
https://read.qxmd.com/read/36916639/immune-response-evolution-in-peanut-epicutaneous-immunotherapy-for-peanut-allergic-children
#17
JOURNAL ARTICLE
Marie Bastin, Warner W Carr, Carla M Davis, David M Fleischer, Jay A Lieberman, S Shahzad Mustafa, Thibault Helleputte, Timothée Bois, Dianne E Campbell, Todd D Green, Matthew Greenhawt
BACKGROUND: Epicutaneous immunotherapy (EPIT) with investigational Viaskin™ Peanut 250 μg (DBV712) has demonstrated statistically superior desensitization versus placebo in peanut-allergic children in clinical trials. It is unclear if serologic biomarkers predict response. METHODS: Serum-specific IgG4 and IgE (whole peanut and components) from subjects enrolled in the phase 3 PEPITES study were examined by exploratory univariate and multivariate analyses to determine trajectories and predictors of treatment response, based upon peanut protein eliciting dose (ED) at Month (M) 12 double-blind placebo-controlled food challenge...
March 14, 2023: Allergy
https://read.qxmd.com/read/36905306/quantitative-analysis-of-urinary-cytokines-in-food-allergic-and-healthy-individuals
#18
LETTER
Alexandra S Lee, Ella S Parsons, Iris Chang, Diane Dunham, R Sharon Chinthrajah, Kari C Nadeau
No abstract text is available yet for this article.
March 11, 2023: Allergy
https://read.qxmd.com/read/36905295/pm-2-5-chemical-constituents-and-allergic-rhinitis-findings-from-a-prospective-cohort-study-in-china
#19
LETTER
Peng Jia, Chuanteng Feng, Tingting Ye, Yin Shao, Shujuan Yang
No abstract text is available yet for this article.
March 11, 2023: Allergy
https://read.qxmd.com/read/36883528/il-4-drastically-decreases-deuterosomal-and-multiciliated-cells-via-alteration-in-progenitor-cell-differentiation
#20
JOURNAL ARTICLE
Hyung-Ju Cho, Youn Wook Chung, Sungmin Moon, Ju Hee Seo, Miran Kang, Jae Sung Nam, Sang Nam Lee, Chang-Hoon Kim, Augustine M K Choi, Joo-Heon Yoon
BACKGROUND: Allergic inflammation affects the epithelial cell populations resulting in goblet cell hyperplasia and decreased ciliated cells. Recent advances in single-cell RNA sequencing (scRNAseq) have enabled the identification of new cell subtypes and genomic features of single cells. In this study, we aimed to investigate the effect of allergic inflammation in nasal epithelial cell transcriptomes at the single-cell level. METHODS: We performed scRNAseq in cultured primary human nasal epithelial (HNE) cells and in vivo nasal epithelium...
March 8, 2023: Allergy
journal
journal
20009
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.