journal
https://read.qxmd.com/read/38610102/long-term-follow-up-of-neutrophil-activation-after-severe-to-critical-sars-cov-2-infection-a-longitudinal-study
#1
JOURNAL ARTICLE
Simon Valentin, Veronique Regnault, Jean-Louis Gueant, Bruno Ribeiro Baptista, Thery Abel, Patrick Lacolley, Frederic Schlemmer, Ari Chaouat, François Chabot, Rosa-Maria Gueant-Rodriguez
No abstract text is available yet for this article.
April 12, 2024: Allergy
https://read.qxmd.com/read/38590291/sm17-a-new-il-17rb-targeting-antibody-ameliorates-disease-progression-in-a-mouse-model-of-atopic-dermatitis
#2
LETTER
Lik Hang Lam, Weimin Li, Wai Chung Wu, Kai Cheung Chow, Wai Yin Dennis Au, Guolin Xu, Ge Wang, Xuchen Qian, Ka Man Ng, Shaik Abdullah Nawabjan, Muthu Iswarya Gandhi Sethuraman, Wai Yan Choi, Billy Kwok Chong Chow, Shui On Leung, Chin Wai Hui
No abstract text is available yet for this article.
April 9, 2024: Allergy
https://read.qxmd.com/read/38588176/preventive-allergen-immunotherapy-with-inhalant-allergens-in-children
#3
REVIEW
Varsha Dwivedi, Sonja Kopanja, Klara Schmidthaler, Justyna Sieber, Christina Bannert, Zsolt Szépfalusi
The efficacy and safety of preventive allergen immunotherapy (pAIT) in children are currently under investigation. Here, we provide an overview of pAIT with respiratory allergens concerning the prevention of new sensitizations, allergic disease onset and progression as well as further immunomodulatory effects. Three databases were searched for clinical pAIT studies in children. Selected publications were reviewed for preventive outcomes according to prevention level (primary, secondary, and tertiary), allergen type, administration route, dose, and treatment duration...
April 8, 2024: Allergy
https://read.qxmd.com/read/38587051/medical-algorithm-diagnosis-and-treatment-of-drug-reaction-with-eosinophilia-and-systemic-symptoms-in-adult-patients
#4
Marie-Charlotte Brüggen, Stephan Traidl, Yasutaka Mitamura, Sarah Walsh, Lars E French, Nicholas Gulati, Elizabeth Phillips, Emanual Maverakis, Saskia Ingen-Housz-Oro
No abstract text is available yet for this article.
April 8, 2024: Allergy
https://read.qxmd.com/read/38581259/am-301-a-barrier-forming-nasal-spray-versus-saline-spray-in-seasonal-allergic-rhinitis-a-randomized-clinical-trial
#5
JOURNAL ARTICLE
Sven Becker, Sachin Deshmukh, Ferdinandus De Looze, Veronica Francardo, Jessie Lee, Anthony McGirr, Zachary Nathan, Christopher Rook, Thomas Meyer
RATIONALE: Saline nasal sprays are frequently used in the management of seasonal allergic rhinitis (SAR) for the cleansing and clearing of aeroallergens from the nasal cavity. Also using a drug-free approach, AM-301 nasal spray is forming a thin film barrier on the nasal mucosa to prevent contact with allergens, trap them, and facilitate their discharge. A clinical trial compared the efficacy, safety, and tolerability of AM-301 and saline spray in SAR. METHODS: A total of 100 patients were randomized 1:1 to self-administer AM-301 or saline 3 × daily for 2 weeks...
April 6, 2024: Allergy
https://read.qxmd.com/read/38577792/prior-respiratory-syncytial-viral-infection-contributes-to-severe-covid-19-illness-a-nationwide-cohort-study
#6
LETTER
Hwan Jin Lee, Min Ji Kim, Jong Seung Kim, Yong Chul Lee, Jae Seok Jeong
No abstract text is available yet for this article.
April 5, 2024: Allergy
https://read.qxmd.com/read/38573073/extracellular-vesicle-mirnas-drive-aberrant-macrophage-responses-in-nsaid-exacerbated-respiratory-disease
#7
JOURNAL ARTICLE
Franziska Hartung, Pascal Haimerl, Sonja Schindela, Veronika Mussack, Benedikt Kirchner, Fiona D R Henkel, Ulrike Bernhardt, Ulrich M Zissler, Rachel Santarella-Mellwig, Michael Pfaffl, Carsten B Schmidt-Weber, Adam M Chaker, Julia Esser-von Bieren
BACKGROUND: Extracellular vesicles (EVs) have been implicated in the pathogenesis of asthma, however, how EVs contribute to immune dysfunction and type 2 airway inflammation remains incompletely understood. We aimed to elucidate roles of airway EVs and their miRNA cargo in the pathogenesis of NSAID-exacerbated respiratory disease (N-ERD), a severe type 2 inflammatory condition. METHODS: EVs were isolated from induced sputum or supernatants of cultured nasal polyp or turbinate tissues of N-ERD patients or healthy controls by size-exclusion chromatography and characterized by particle tracking, electron microscopy and miRNA sequencing...
April 4, 2024: Allergy
https://read.qxmd.com/read/38573058/patterns-of-allergen-recognition-in-ligustrum-polysensitized-patients-an-immunoproteomics-approach
#8
LETTER
Raúl Porras-Gutiérrez-de-Velasco, Blessy Maruthukunnel-Mani, Juan Carlos Vizuet-de-Rueda, Josaphat Miguel Montero-Vargas, Luis M Teran
No abstract text is available yet for this article.
April 4, 2024: Allergy
https://read.qxmd.com/read/38563695/eaaci-guidelines-on-environmental-science-for-allergy-and-asthma-the-impact-of-short-term-exposure-to-outdoor-air-pollutants-on-asthma-related-outcomes-and-recommendations-for-mitigation-measures
#9
JOURNAL ARTICLE
Ioana Agache, Isabella Annesi-Maesano, Lorenzo Cecchi, Benedetta Biagioni, Kian Fan Chung, Bernard Clot, Gennaro D'Amato, Athanasios Damialis, Stefano Del Giacco, Javier Dominguez-Ortega, Carmen Galàn, Stefanie Gilles, Stephen Holgate, Mohamed Jeebhay, Stelios Kazadzis, Kari Nadeau, Nikolaos Papadopoulos, Santiago Quirce, Joaquin Sastre, Fiona Tummon, Claudia Traidl-Hoffmann, Jolanta Walusiak-Skorupa, Marek Jutel, Cezmi A Akdis
The EAACI Guidelines on the impact of short-term exposure to outdoor pollutants on asthma-related outcomes provide recommendations for prevention, patient care and mitigation in a framework supporting rational decisions for healthcare professionals and patients to individualize and improve asthma management and for policymakers and regulators as an evidence-informed reference to help setting legally binding standards and goals for outdoor air quality at international, national and local levels. The Guideline was developed using the GRADE approach and evaluated outdoor pollutants referenced in the current Air Quality Guideline of the World Health Organization as single or mixed pollutants and outdoor pesticides...
April 2, 2024: Allergy
https://read.qxmd.com/read/38563683/targeting-il-13-with-tralokinumab-normalizes-type-2-inflammation-in-atopic-dermatitis-both-early-and-at-2%C3%A2-years
#10
JOURNAL ARTICLE
Emma Guttman-Yassky, Kenji Kabashima, Delphine Staumont-Salle, Walter K Nahm, Sylvia Pauser, Joel Correa Da Rosa, Britta Cathrina Martel, Daniel Elenius Madsen, Mads Røpke, Petra Arlert, Louise Steffensen, Andrew Blauvelt, Kristian Reich
BACKGROUND: Tralokinumab is a monoclonal antibody that specifically neutralizes interleukin (IL)-13, a key driver of skin inflammation and barrier abnormalities in atopic dermatitis (AD). This study evaluated early and 2-year impacts of IL-13 neutralization on skin and serum biomarkers following tralokinumab treatment in adults with moderate-to-severe AD. METHODS: Skin biopsies and blood samples were evaluated from a subset of patients enrolled in the Phase 3 ECZTRA 1 (NCT03131648) and the long-term extension ECZTEND (NCT03587805) trials...
April 2, 2024: Allergy
https://read.qxmd.com/read/38558416/algorithms-in-allergy-diagnosis-pathogenesis-and-treatment-of-chronic-spontaneous-urticaria
#11
Allen P Kaplan, Marta Ferrer
No abstract text is available yet for this article.
April 1, 2024: Allergy
https://read.qxmd.com/read/38553995/ige-mediated-allergic-diseases-are-associated-with-alzheimer-s-disease
#12
LETTER
Andrzej Bozek, Magdalena Krupka-Olek, Aleksandra Kawczyk Krupka
No abstract text is available yet for this article.
March 30, 2024: Allergy
https://read.qxmd.com/read/38551028/patients-values-and-preferences-for-health-states-in-allergic-rhinitis-an-artificial-intelligence-supported-systematic-review
#13
REVIEW
Jan Brozek, Ewa Borowiack, Ewelina Sadowska, Artur Nowak, Bernardo Sousa-Pinto, Rafael José Vieira, Antonio Bognanni, Juan Jose Yepes Nuñez, Yuan Zhang, Torsten Zuberbier, Jean Bousquet, Holger J Schünemann
BACKGROUND: Allergic rhinitis (AR) impacts patients' physical and emotional well-being. Assessing patients' values and preferences (V&P) related to AR is an essential part of patient-centered care and of the guideline development process. We aimed to systematically summarize the information about patients' V&P on AR and its symptoms and impact on daily life. METHODS: We conducted systematic review in a MEDLINE, Embase, PsychInfo, and CINAHL databases. We included studies which quantitatively assessed patients' V&P for specific outcomes in AR by assessing utilities, applying discrete choice approaches, or rating and ranking outcomes...
March 29, 2024: Allergy
https://read.qxmd.com/read/38534020/environmental-exposures-drive-the-development-of-allergic-diseases
#14
EDITORIAL
Luo Zhang, Cezmi A Akdis
No abstract text is available yet for this article.
March 27, 2024: Allergy
https://read.qxmd.com/read/38532561/interleukin-31-transcription-in-a-canine-model-of-acute-atopic-dermatitis-does-not-correlate-with-t-cell-infiltration
#15
LETTER
Nicky Craig, Kim Ahrens, Rachel Wilkes, Tanja Opriessnig, Deborah V Hoyle, Barry Bradford, Scott Maxwell, Jorge Del Pozo, Maciej Parys, Takanori Kitamura, Rosanna Marsella
No abstract text is available yet for this article.
March 26, 2024: Allergy
https://read.qxmd.com/read/38532556/mast-cell-activation-identified-through-urine-mediators
#16
JOURNAL ARTICLE
Matthew P Giannetti, Grace Godwin, Julia Middlesworth, Andrew Espeland, Jennifer Nicoloro-SantaBarbara, Mariana Castells
No abstract text is available yet for this article.
March 26, 2024: Allergy
https://read.qxmd.com/read/38525846/response-to-correspondence-to-short-course-subcutaneous-treatment-with-pq-grass-strongly-improves-symptom-and-medication-scores-in-grass-allergy
#17
LETTER
P J de Kam, S Zielen, J A Bernstein, U Berger, M Berger, M Cuevas, D Cypcar, A Fuhr-Horst, W A Greisner, M Jandl, S Laßmann, M Worm, J Matz, E Sher, C Smith, G C Steven, R Mösges, M H Shamji, L DuBuske, F Borghese, K Oluwayi, T Zwingers, M Seybold, O Armfield, M D Heath, S J Hewings, M F Kramer, M A Skinner
No abstract text is available yet for this article.
March 25, 2024: Allergy
https://read.qxmd.com/read/38523510/chicken-meat-allergy-in-children-complex-sensitization-profiles-with-newly-described-allergen-candidates
#18
JOURNAL ARTICLE
T Guiddir, H Sénéchal, M A Selva, R Couderc, I Swoboda, C Hilger, A Kuehn, Y Chantran, S Yen-Nicolaÿ, T Vrai, G Ruellou, B Baudin, P Poncet, A Nemni
No abstract text is available yet for this article.
March 25, 2024: Allergy
https://read.qxmd.com/read/38516981/lupin-a-potential-hidden-food-anaphylaxis-allergen-an-alert-from-the-allergy-vigilance-network%C3%A2
#19
JOURNAL ARTICLE
Guillaume Pouessel, Dominique Sabouraud-Leclerc, Pascale Beaumont, Amandine Divaret-Chauveau, Eléna Bradatan, Pascale Dumond, Yasemin Karaca, Jean-Marie Renaudin, Carine Metz-Favre, Delphine Delalande, Anne-Karine Correard, Sélina Tscheiller, Xavier Van der Brempt
No abstract text is available yet for this article.
March 22, 2024: Allergy
https://read.qxmd.com/read/38483174/nasal-allergen-neutralizing-antibodies-correlate-closely-with-tolerated-intranasal-allergen-challenge-dose-following-grass-pollen-subcutaneous-immunotherapy-in-patients-with-local-allergic-rhinitis
#20
JOURNAL ARTICLE
Ibon Eguiluz-Gracia, Rebecca V Parkin, Janice A Layhadi, Elizabeth Palmer, Xun Meng, Rongfei Zhu, Umit Sahiner, Stephen R Durham, Maria Jose Torres, Cristobalina Mayorga, Carmen Rondon, Mohamed H Shamji
BACKGROUND: Local allergic rhinitis (LAR) is defined by chronic nasal symptoms, absence of atopy, positive nasal allergen challenge (NAC) and a good response to subcutaneous allergen immunotherapy (SCIT). We sought to investigate SCIT capacity to induce local and systemic blocking antibodies in LAR patients. METHODS: A RDBPC study of grass SCIT was performed, with participants receiving either SCIT (Group A; n = 10) or placebo (Group B; n = 14) in the first 6 months...
March 14, 2024: Allergy
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