journal
https://read.qxmd.com/read/38537051/forecasting-the-effect-of-hiv-targeted-interventions-on-the-age-distribution-of-people-living-with-hiv-a-case-study-from-kenya
#41
JOURNAL ARTICLE
Melissa C Schnure, Parastu Kasaie, David W Dowdy, Becky L Genberg, Emily A Kendall, Anthony T Fojo
OBJECTIVES: Expansion of ART and increases to life expectancy have led to aging among people living with HIV (PWH). DESIGN: Kenyan decisionmakers need accurate forecasts of the age distribution of PWH to inform future policies. METHODS: We developed a model of HIV in Kenya, calibrated to historical estimates of HIV epidemiology. We forecasted changes in population size and age distribution of new HIV infections and PWH under the status quo and under scale-up of HIV services...
March 27, 2024: AIDS
https://read.qxmd.com/read/38526550/impact-of-influenza-and-pneumococcal-vaccines-on-hiv-persistence-and-immune-dynamics-during-suppressive-antiretroviral-therapy
#42
JOURNAL ARTICLE
Sara Gianella, Christy Anderson, Antoine Chaillon, Alan Wells, Magali Porrachia, Gemma Caballero, Milenka Vargas, Joseph Lonergan, Brendon Woodworth, Noah Gaitan, Stephen A Rawlings, Leticia Muttera, Liliana Harkness, Susan J Little, Susanne May, Davey Smith
OBJECTIVE: :We sought to determine if standard influenza and pneumococcal vaccines can be used to stimulate HIV reservoirs during antiretroviral therapy (ART). DESIGN: :Prospective, randomized, double-blinded, placebo-controlled, crossover trial of two clinically recommended vaccines (influenza and pneumococcal). METHODS: :Persons with HIV on ART (N = 54) were enrolled in the clinical trial. Blood was collected at baseline and days 2,4,7,14 and 30 postimmunizations...
March 25, 2024: AIDS
https://read.qxmd.com/read/38518076/concordance-between-daily-diary-reported-prep-intake-and-intraerythrocytic-tenofovir-diphosphate-tfv-dp-in-the-amsterdam-prep-demonstration-project
#43
JOURNAL ARTICLE
Eline S Wijstma, Vita W Jongen, Anders Boyd, Mark van den Elshout, Henry J C de Vries, Udi Davidovich, Peter L Anderson, Maria Prins, Elske Hoornenborg, Maarten F Schim van der Loeff
OBJECTIVE: We assessed the association and concordance between self-reported oral preexposure prophylaxis (PrEP) intake in a diary app and intraerythrocytic drug metabolite concentrations. DESIGN: AMPrEP was a prospective demonstration study providing daily and event-driven PrEP to MSM in Amsterdam, the Netherlands (2015-2020). METHODS: Participants could record their PrEP intake in a diary app. Dried blood spots (DBS) were taken at 6, 12, 24, and 48 months and analysed for tenofovir diphosphate (TFV-DP) and emtricitabine triphosphate (FTC-TP) concentrations...
March 21, 2024: AIDS
https://read.qxmd.com/read/38507586/cumulative-exposure-to-depressive-symptoms-and-all-cause-mortality-among-adults-living-with-hiv-in-kenya-nigeria-tanzania-and-uganda
#44
JOURNAL ARTICLE
Christopher G Kemp, Brian W Pence, Jennifer Velloza, Tessa Concepcion, Modhurima Moitra, Michael Iroezindu, Emmanuel Bahemana, Hannah Kibuuka, Michael Semwogerere, John Owuoth, Jonah Maswai, Rither Langat, Allahna L Esber, Nicole F Dear, Ajay Parikh, Trevor A Crowell, Julie A Ake, Christina S Polyak, Pamela Y Collins
OBJECTIVE: :We estimated the effects of cumulative exposure to depressive symptoms on risk of all-cause mortality among people living with HIV in four African countries. DESIGN: :Analysis of prospective cohort data. METHODS: :The African Cohort Study (AFRICOS) is a prospective cohort of people receiving care at twelve clinics in Kenya, Nigeria, Tanzania, and Uganda. Every six months from January 2013 to May 2020, participants underwent laboratory monitoring, structured surveys, and assessment of depressive symptom severity using the Center for Epidemiologic Studies Depression Scale (CES-D)...
March 20, 2024: AIDS
https://read.qxmd.com/read/38507584/regional-variation-in-weight-change-after-the-transition-to-dolutegravir-a-prospective-cohort-study-in-uganda-and-south-africa
#45
JOURNAL ARTICLE
Richard Migisha, Geoffrey Chen, Winnie R Muyindike, Taing Nandi Aung, Victoria Nanfuka, Nimusiima Komukama, Nomathemba Chandiwana, Gugulethu Shazi, Dessie Tien, Mahomed-Yunus S Moosa, Ravindra K Gupta, Deenan Pillay, Vincent C Marconi, Bethany Hedt-Gauthier, Willem D F Venter, Mark J Siedner, Suzanne M McCluskey, Jennifer Manne-Goehler
BACKGROUND: People with HIV (PWH) on integrase inhibitor-based regimens may be at risk of excess weight gain, but it is unclear if this risk is consistent across settings. We assessed weight change over 48 weeks among PWH who were transitioned to tenofovir disoproxil fumarate/lamivudine/dolutegravir (TLD). DESIGN: We conducted a prospective cohort study at public-sector HIV clinics in Uganda and South Africa. METHODS: Eligible participants were adults who were transitioned to TLD...
March 20, 2024: AIDS
https://read.qxmd.com/read/38507582/self-rated-health-and-hiv-outcomes-among-adults-with-diagnosed-hiv-medical-monitoring-project-united-states-2020-21
#46
JOURNAL ARTICLE
Preetam A Cholli, Kate M Buchacz, Norma S Harris, Stacy M Crim, Xin Yuan, Yunfeng Tie, Linda J Koenig, Linda Beer
OBJECTIVES: To evaluate associations between self-rated health (SRH) and care outcomes among United States adults with diagnosed HIV infection. DESIGN: We analyzed interview and medical record data collected during June 2020-May 2021 from the Medical Monitoring Project, a complex, nationally representative sample of 3,692 people with HIV (PWH). Respondents reported SRH on a 5-point Likert type scale (poor to excellent), which we dichotomized into "good or better" and "poor or fair"...
March 20, 2024: AIDS
https://read.qxmd.com/read/38507583/incidence-of-non-aids-defining-comorbidities-among-young-adults-with-perinatally-acquired-hiv-in-north-america-2000-2019
#47
JOURNAL ARTICLE
Nel Jason L Haw, Catherine R Lesko, Derek K Ng, Jennifer Lam, Raynell Lang, Mari M Kitahata, Heidi Crane, Joseph Eron, M John Gill, Michael A Horberg, Maile Karris, Mona Loutfy, Kathleen A Mcginnis, Richard D Moore, Keri Althoff, Allison Agwu
OBJECTIVE: To describe the incidence of diabetes mellitus type 2 (T2DM), hypercholesterolemia, hypertriglyceridemia, hypertension, and chronic kidney disease (CKD) from 2000 to 2019 among North American adults with perinatally-acquired HIV (PHIV) aged 18 to 30. DESIGN: Description of outcomes based on electronic health records for a cohort of 375 young adults with PHIV enrolled in routine HIV care at clinics contributing data to the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD)...
March 19, 2024: AIDS
https://read.qxmd.com/read/38499478/mortality-of-children-and-adolescents-co-infected-with-tuberculosis-and-hiv-a-systematic-review-and-meta-analysis
#48
JOURNAL ARTICLE
Fei-Hong Hu, Xiao-Lei Tang, Meng-Wei Ge, Yi-Jie Jia, Wan-Qing Zhang, Wen Tang, Lu-Ting Shen, Wei Du, Xiao-Peng Xia, Hong-Lin Chen
OBJECTIVE: Children and adolescents with HIV infection are well-known to face a heightened risk of tuberculosis. However, the exact mortality rates and temporal trends of those with HIV-TB co-infection remain unclear. We aimed to identify the overall mortality and temporal trends within this population. METHODS: PubMed, Web of Science, and Embase were employed to search for publications reporting on the mortality rates of children and adolescents with HIV-TB co-infection from inception to March 2, 2024...
March 18, 2024: AIDS
https://read.qxmd.com/read/38814721/albumin-white-blood-cell-count-and-body-mass-index-improve-discrimination-of-mortality-in-hiv-positive-individuals-erratum
#49
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
July 1, 2024: AIDS
https://read.qxmd.com/read/38814720/decay-of-coronavirus-disease-2019-mrna-vaccine-induced-immunity-in-people-with-hiv-erratum
#50
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
July 1, 2024: AIDS
https://read.qxmd.com/read/38814719/towards-a-refined-understanding-of-cerebrospinal-fluid-cxcl13-in-neurosyphilis-diagnosis-among-people-with-hiv
#51
LETTER
Ricardo de S Carvalho, Isabelle C Rangel, Fernando R A Ferry
No abstract text is available yet for this article.
July 1, 2024: AIDS
https://read.qxmd.com/read/38814718/further-considerations-on-the-use-of-cerebrospinal-fluid-c-x-c-motif-chemokine-ligand-13-in-the-diagnosis-of-neurosyphilis-among-people-with-hiv
#52
LETTER
Mattia Trunfio, Stefano Bonora, Giovanni di Perri, Andrea Calcagno
No abstract text is available yet for this article.
July 1, 2024: AIDS
https://read.qxmd.com/read/38814717/concerns-and-clarifications-regarding-the-article-virological-weight-and-drug-resistance-outcomes-among-patients-initiating-a-dolutegravir-based-first-line-art-regimen-in-zimbabwe
#53
LETTER
https://read.qxmd.com/read/38814716/prescriptions-of-generic-antiretroviral-drugs-in-three-healthcare-centers-in-the-paris-area-france
#54
JOURNAL ARTICLE
Pierre Leroy, Sylvain Diamantis, Pierre-Olivier Sellier, Gwenn Hamet, Alexandre Brun, Willy Rozenbaum, Jean-Michel Molina
In a retrospective study conducted in three hospitals in Paris, generic antiretroviral accounted for 30.2% of all prescriptions. Tenofovir disoproxil/emtricitabine (TDF/FTC) was the most prescribed generic ART (82.3% of generic prescriptions). Generic ART (gART) was more likely to be prescribed to women, to patients less than 50 years, and with recent HIV diagnosis less than 3 years. Physicians prescribed more gART if they were men, older than 55 years or worked at a university teaching hospital...
July 1, 2024: AIDS
https://read.qxmd.com/read/38814715/low-cabotegravir-trough-concentrations-without-oral-lead-in-in-patients-with-hiv-1-switching-to-long-acting-cabotegravir-and-rilpivirine
#55
JOURNAL ARTICLE
Emma Rubenstein, Myriam Diemer, Lauriane Goldwirt, Caroline Lascoux-Combe, Marie-Laure Chaix, Agathe Rami, Diane Ponscarme, Matthieu Lafaurie, Blandine Denis, Nathalie De Castro, Julien Gras, Geoffroy Liegeon, Pierre-Olivier Sellier, Laure Deville, Sylvie Chevret, Constance Delaugerre, Jean-Michel Molina
In a cohort of 72 consecutive virologically-suppressed patients with HIV-1 switching to long-acting cabotegravir and rilpivirine, we observed low cabotegravir trough concentrations 1 and 3 months after the first injection, with a significant association with no oral lead-in at 1 month [odds ratio (OR) = 6.3 [95% confidence interval (CI) 1.7-29.5], P = 0.01] and three months (OR = 5.6 [95% CI 1.3-29.7], P = 0.03), and with high BMI at 1 month (OR = 1...
July 1, 2024: AIDS
https://read.qxmd.com/read/38814714/hiv-related-gut-damage-persists-long-term-in-perinatally-acquired-hiv-and-is-associated-with-insulin-resistance
#56
LETTER
Enass A Abdel-Hameed, Sepiso K Masenga
No abstract text is available yet for this article.
July 1, 2024: AIDS
https://read.qxmd.com/read/38814713/is-early-initiation-of-antiretroviral-therapy-important
#57
EDITORIAL
Dean L Winslow
No abstract text is available yet for this article.
July 1, 2024: AIDS
https://read.qxmd.com/read/38814712/the-effect-of-care-interruptions-on-mortality-in-adults-resuming-antiretroviral-therapy
#58
JOURNAL ARTICLE
Haroon Moolla, Mary-Ann Davies, Claire Davies, Jonathan Euvrard, Hans W Prozesky, Matthew P Fox, Catherine Orrell, Per Von Groote, Leigh F Johnson
OBJECTIVE: To estimate the relative rate of all-cause mortality amongst those on antiretroviral treatment (ART) with a history of interruptions compared with those with no previous interruptions in care. DESIGN: Retrospective cohort study. METHODS: We used data from four South African cohorts participating in the International epidemiology Databases to Evaluate AIDS Southern Africa collaboration. We included adults who started ART between 2004 and 2019...
July 1, 2024: AIDS
https://read.qxmd.com/read/38691055/navigating-the-intersection-minority-stress-mental-health-and-hiv-care-in-the-philippines
#59
JOURNAL ARTICLE
Rowalt Alibudbud
No abstract text is available yet for this article.
June 1, 2024: AIDS
https://read.qxmd.com/read/38691054/dolutegravir-induced-severe-sideroblastic-anemia
#60
LETTER
Sandrine Lemoine, Maxime Bobo, Laurent Hocqueloux, Eric Legac, Thierry Prazuck
No abstract text is available yet for this article.
June 1, 2024: AIDS
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