Acta Paediatrica

AIM: to evaluate the incidence and outcome of secondary Immune thrombocytopenia (ITP) in a large cohort of pediatric Spanish patients. METHODS: a retrospective observational study was conducted in two pediatric University hospitals in Spain between 2009 and 2019, which included children from 4 months to 18-year-old diagnosed with ITP. Data were recorded from clinical charts: gender, age at diagnosis, coexisting condition and associated characteristics, outcome and treatment...

AIM: To examine the contributions of specific neuro-cognitive skills to behaviour problems in children born very preterm. METHODS: We assessed children born <30 weeks' gestation or <1500g at age 7 years using subtests of the Wechsler Intelligence Scale for Children Fourth Edition, performance and questionnaire-based measures of executive function, and Child Behavior Checklist and Teacher Rating Form. We evaluated the contributions of IQ and executive function to behaviour problems and the moderating effect of sex using multiple regression...

I would like to thank Peny and Valind (1) for raising a number of issues with regard to my recent paper in Acta Paediatrica, which was based on parental reports of what appeared to be long COVID in Sweden (2). The parents approached a number of medical professionals, including me, following discussions on social media about how their children were experiencing worrying ongoing symptoms during the current COVID-19 pandemic.

We read with interest the article by Jonas F. Ludvigsson published in Acta Pediatrica 1 . While it is amongst the first articles published on an interesting and timely topic there are several issues with this case series that warrants further discussion and calls into the question the findings. Firstly, the author state that the clinical report is solely based on the reports from the parents of each of the five children described - what measures were taken to validate these reports by asking for copies of medical notes or through contact with the treating physicians?...

AIM: To assess the clinical picture underlying apparent life threatening events (ALTEs) occurring in infants with achondroplasia and provide guidance for evaluation after an event. METHODS: A population of 477 individuals with achondroplasia was retrospectively reviewed and information regarding possible ALTEs were recorded in a REDCap database. RESULTS: ALTEs occurred in the first year of life in 18 of 477 individuals (3.8%). Most (14/18, 78%) occurred in the first six months of life and presented as episodes of apnea and/or seizures...

In their letter, Meyer et al. cite the fact that propofol is not registered for use in infants less than one month of age.2 We are well aware of this fact. This does not only apply to propofol but is the case for a substantial amount of drugs used in the neonatal population. In a recent survey, Flint et al. showed that 23% of drug prescriptions were off-label in relation to neonatal age and over half of all newborns admitted to the neonatal intensive care unit (NICU) received at least one off-label drug.

It is estimated that around 26,000 people live without a residence permit in Denmark and that 9% of undocumented migrants in Europe are younger than 18 years (1, 2). According to Danish law, undocumented children have the right to same health services including non-acute healthcare as children who are Danish residents. However, in practice this is not possible as routine healthcare requires legal registration with the authorities and also because most Danish healthcare professionals are not aware of how to get financial approval...

In their prospepective study in very preterm neonates, De Kort et al. analysed the effects of different propofol starting doses as premedication for endotracheal intubation on blood pressure (1.0 mg/kg (n = 30), 1.5 mg/kg (n = 23) or 2.0 mg/kg (n = 26)) [1]. The authors demonstrated that propofol caused a dose-dependent profound and protracted drop in blood pressure which was mainly dependent on the initial propofol starting dose rather than the cumulative propofol dose.

Although children seem to be less affected than adults by COVID-19, Italianpaediatric hospitals have had to significantly reorganise services to deal with the pandemic. These include thetertiary-level Gaslini Children's Hospital in Genoa, which handles around 35,000 emergency room (ER) visits per year. The Government lockdown has dramatically reduced ER admissions and delayed programmed admissions (1).

Although COVID-19 tends to affect older people more severely, women of reproductive age are not spared. Based on perinatal COVID-19 data we express concerns about theoretical adverse consequences particularly to the offspring, in the framework of non-communicable diseases, which develop slowly across the life-course. The trajectory of risk commences early, in adolescence and the pre/peri-conceptional period to the first years of life.

No abstract text is available yet for this article.

No abstract text is available yet for this article.

AIM: To evaluate health-related quality of life, mental health and treatment-related stress responses in children with primary antibody deficiency and both their parents. METHODS: Children and their parents completed the standardised questionnaires Pediatric Quality of life Inventory, Strength and Difficulties Questionnaire and Impact of Event Scale. Parents also completed standardised questionnaires regarding their own mental health and quality of life. The results were compared to those of healthy children, kidney transplanted children and children in remission from acute lymphoblastic leukaemia...

The 2020 recommendations from the International Liaison Committee on Resuscitation is an improved version of the 2015 version. The algorithm and 15 procedures are unchanged from 2015, but there are six procedures with new or changed recommendations. One new recommendation is for there to be briefing/debriefing following neonatal resuscitation. Procedures with changed suggestions/recommendations are: suctioning of non-vigorous infants delivered through meconium-stained amniotic fluid, sustained inflation of preterm infants, optimizing epinephrine (adrenaline), vascular access, and discontinuing resuscitative efforts...

Italy was the first western country to be seriously affected by COVID-19. As hospitals became overwhelmed with cases in spring 2020, we saw a parallel decrease in admissions for other medical conditions, even serious and critical diseases (1). The tertiary Santobono-Pausilipon children's hospital in Naples provides the only 24/7 endoscopy paediatric service in the Campania Region in southern Italy. In 2019, we handled 1,247 emergency department visits due to ingestion of caustic substances or foreign bodies...

During neurally adjusted ventilatory assist (NAVA) both the timing and degree of ventilatory assist are controlled by the patient's respiratory center (1) resulting in improved synchrony and lower peak inspiratory pressures and lower oxygen requirements compared with conventional ventilation in low birth weight infants (2,3). However, there are no randomized controlled trials yet available evaluating the effects of NAVA ventilation on the neurodevelopmental outcomes, nor are there studies reporting the use of NAVA ventilation as a standard neonatal intensive care unit practice in extremely preterm infants...

AIM: Separating infants and their parents after a Caesarean section is still the routine care worldwide. This study investigated three caregiving models on the wakefulness and physiological parameters of full-term infants after an elective Caesarean section. METHODS: Newborn infants born in a Chilean public hospital in 2009-12 were randomised to three groups: cot, fathers' arms or skin-to-skin contact with their father. They were assessed at 15-minute intervals, from 45 to 120 minutes after the Caesarean section...

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.