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Acta Anaesthesiologica Scandinavica

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https://read.qxmd.com/read/30761530/post-extubation-continuous-positive-airway-pressure-improves-oxygenation-after-pediatric-laparoscopic-surgery-a-randomized-controlled-trial
#1
Hala S Abdel-Ghaffar, Hamdy A Youseff, Fatma A Abdelal, Mohamed A Osman, Jehan A Sayed, Mohamed Amir Fathy Riad, Marwa M Abdel-Rady
BACKGROUND: Effects of intraoperative recruitment maneuvers (RMs) on oxygenation and pulmonary compliance are lost during recovery if high inspired oxygen and airway suctioning are used. We investigated the effect of post-extubation noninvasive CPAP mask application on the alveolar arterial oxygen difference [(A-a) DO2 ] after pediatric laparoscopic surgery. METHODS: Sixty patients (1-6 years) were randomly allocated to three groups of 20 patients, to receive zero end-expiratory pressure (ZEEP group), RM with decremental PEEP titration only (RM group), or followed with post-extubation CPAP for 5 minutes (RM-CPAP group)...
February 14, 2019: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/30734281/multivariable-models-using-administrative-data-and-biomarkers-to-adjust-for-case-mix-in-the-icu
#2
Miklos Lipcsey, Anna Aronsson, Anders Larsson, Henrik Renlund, Rolf Gedeborg
BACKGROUND: Routinely collected laboratory biomarkers could improve control of confounding from disease severity in non-interventional studies of general intensive care unit (ICU) patients. Their ability to predict both short- and long-term mortality was evaluated. METHODS: The performance of age, sex, Charlson co-morbidity index, and baseline values of ten predefined blood biomarkers as predictors of 30-day and 1-year mortality was evaluated in 5505 general ICU stays...
February 8, 2019: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/30729510/endotracheal-tube-cuff-pressure-changes-during-manual-cuff-pressure-control-manoeuvres-a-call-for-continuous-cuff-pressure-regulation
#3
LETTER
Bert Maertens, Stijn Blot
No abstract text is available yet for this article.
February 6, 2019: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/30729503/response-to-the-letter-by-drs-bothma-and-schlimp-regarding-our-manuscript-iatrogenic-cerebral-gas-embolism-a-systematic-review-of-case-reports
#4
LETTER
Dyveke S Hatling, Anne Høgset, Anne Berit Guttormsen, Bernd Müller
No abstract text is available yet for this article.
February 6, 2019: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/30729498/incidence-of-severe-critical-events-in-paediatric-anaesthesia-in-scandinavia-secondary-analysis-of-anaesthesia-practice-in-children-observational-trial-apricot
#5
Tom G Hansen, Wenche Bakken Børke, Mika H Isohanni, Albert Castellheim
BACKGROUND: The Anaesthesia PRactice In Children Observational Trial (APRICOT) in 261 European hospitals revealed a 5.2% incidence of severe critical events in the perioperative period and wide variability in practice. METHODS: A sub-analysis of the Scandinavian data was undertaken to investigate differences from the rest of Europe in the incidence and nature of perioperative severe critical events and to attempt to identify areas for quality improvement. FINDINGS: In the Scandinavian cohorts of 1520 paediatric patients out of 31 127 patients, the overall incidence of perioperative severe critical events was lower than the rest of Europe (4...
February 6, 2019: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/30729495/empirical-metronidazole-for-patients-with-severe-bacterial-infection-a-systematic-review-with-meta-analysis-and-trial-sequential-analysis
#6
REVIEW
Marie Warrer Petersen, Anders Perner, Andreas Bender Jonsson, Marjan Bahador, Fredrik Sjövall, Morten Hylander Møller
BACKGROUND: Metronidazole is the preferred empirical anti-anaerobic agent for patients with suspected anaerobic infection. The balance between benefits and harms of empirical metronidazole is unclear. We aimed to assess patient-important benefits and harms of empirical metronidazole vs placebo/no treatment in adult patients with severe bacterial infection of any origin. METHODS: We conducted a systematic review with meta-analysis and trial sequential analysis of randomized clinical trials assessing empirical metronidazole vs placebo/no treatment in adult hospitalized patients with severe bacterial infection...
February 6, 2019: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/30701545/measuring-pain-physiological-and-self-rated-measurements-in-relation-to-pain-stimulation-and-anxiety
#7
Hanne Storm, Anders Günther, Peter Victor Sackey, Jens Bernhardsson, Anna Bjärtå
INTRODUCTION: The aim of the present study was to investigate how emotions influence pain, measured by one subjective self-rated measure, the numeric rating scale (NRS), and one objective physiological measure, the number of skin conductance responses (NSCR). METHOD: Eighteen volunteers were exposed to conditions with pictorial emotional stimuli (neutral, positive, negative), authentic ICU-sound (noise, no-noise) and electrical stimulation (pain, no-pain) individually titrated to induce moderate pain...
January 31, 2019: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/30701537/dexmedetomidine-for-the-management-of-delirium-in-critically-ill-patients-a-protocol-for-a-systematic-review
#8
REVIEW
Mathias Maagaard, Marija Barbateskovic, Anders Perner, Janus C Jakobsen, Jørn Wetterslev
BACKGROUND: Delirium is a common complication in critically ill patients and carries an increased risk of mortality and morbidity. Dexmedetomidine can potentially treat delirium by diminishing predisposing factors. The evidence regarding the use of dexmedetomidine in the management of delirium is conflicting. This protocol aims to identify the beneficial and harmful effects of dexmedetomidine in the management of delirium. METHODS: This protocol uses the recommendations of the Cochrane Collaboration, the Preferred Report Items of Systematic reviews with Meta-Analysis Protocols, and the eight-step assessment procedure suggested by Jakobsen and colleagues...
January 31, 2019: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/30701544/reporting-and-interpreting-missing-health-related-quality-of-life-data-in-intensive-care-trials-protocol-for-a-systematic-review
#9
REVIEW
Maj-Brit Nørregaard Kjaer, Martin Bruun Madsen, Morten Hylander Møller, Ingrid Egerod, Anders Perner
BACKGROUND: Health-related quality of life is often used as a patient-important outcome in randomized clinical trials in the intensive care unit setting. Missing data are a challenge in randomized clinical trials as they hamper the interpretation of the results, but the extent and handling of missing health-related quality of life data are unknown. Therefore, we aim to describe and evaluate the extent, pattern, and handling of missing health-related quality of life data in randomized clinical trials conducted in the intensive care unit setting...
January 30, 2019: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/30697688/diaphragm-sparing-effect-of-the-infraclavicular-subomohyoid-block-vs-low-volume-interscalene-block-a-randomized-blinded-study
#10
Ahmad M Taha, Nagib A Yurdi, Mohamed I Elahl, Ahmed M Abd-Elmaksoud
BACKGROUND: Both low volume interscalene and infraclavicular-subomohyoid blocks were suggested to provide shoulder analgesia with low risk of phrenic nerve block. The aim of this study was to compare the frequency of the phrenic nerve block between these two techniques. METHOD: Seventy-two patients scheduled for shoulder arthroscopy were included in this randomized controlled blind study. Before induction of general anesthesia, patients received low volume interscalene block using 5 mL of ropivacaine 0...
January 30, 2019: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/30690713/predictive-performance-of-a-new-pharmacokinetic-model-for-propofol-in-underweight-patients-during-target-controlled-infusion
#11
Jung-Min Yi, Il Doh, Seok-Hwan Lee, Soo-Young Kim, Yong-Hun Lee, Eun-Kyung Lee, Soo-Han Lee, Byung-Moon Choi, Gyu-Jeong Noh
BACKGROUND: In a previous study, the modified Marsh and Schnider models respectively showed negatively- and positively-biased predictions in underweight patients. To overcome this drawback, we developed a new pharmacokinetic propofol model-the Choi model-for use in underweight patients. In the present study, we evaluated the predictive performance of the Choi model. METHODS: Twenty underweight patients undergoing elective surgery received propofol via TCI using the Choi model...
January 28, 2019: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/30676644/trustworthy-systematic-reviews-can-journals-do-more
#12
LETTER
Ethan Butler, Anders Granholm, Anders Aneman
No abstract text is available yet for this article.
January 24, 2019: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/30676641/target-controlled-infusion-for-special-populations-how-different-is-different-enough
#13
EDITORIAL
Douglas J Eleveld
No abstract text is available yet for this article.
January 24, 2019: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/30675717/can-we-trust-power-analysis-on-post-hoc-studies-a-paradigm-from-out-of-hospital-cardiac-arrest
#14
LETTER
Michele C Vassallo, Fabiana Tartamella, Pradipta Bahkta
No abstract text is available yet for this article.
January 24, 2019: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/30675715/iatrogenic-cerebral-gas-embolism-pneumocephalus-and-the-concept-of-retrograde-cerebral-venous-gas-embolism
#15
LETTER
Pieter A Bothma, Christoph J Schlimp
No abstract text is available yet for this article.
January 23, 2019: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/30671925/dexmedetomidine-for-the-prevention-of-delirium-in-critically-ill-patients-a-protocol-for-a-systematic-review
#16
REVIEW
Mathias Maagaard, Marija Barbateskovic, Anders Perner, Janus Christian Jakobsen, Jørn Wetterslev
BACKGROUND: Delirium is a common complication in critically ill patients and carries an increased risk of mortality and morbidity. Dexmedetomidine can potentially prevent delirium by diminishing predisposing factors. The evidence regarding the use of dexmedetomidine in preventing delirium is conflicting. This protocol aims to identify the beneficial and harmful effects of dexmedetomidine in the prevention of delirium. METHODS: This protocol uses the recommendations of the Cochrane Collaboration, the Preferred Report Items of Systematic Reviews with Meta-Analysis Protocols, and the eight-step assessment procedure suggested by Jakobsen and colleagues...
January 23, 2019: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/30656651/clinical-practice-guideline-on-atraumatic-pencil-point-vs-conventional-needles-for-lumbar-puncture-endorsement-by-the-scandinavian-society-of-anaesthesiology-and-intensive-care-medicine
#17
REVIEW
Marius Rehn, Michelle S Chew, Klaus T Olkkola, Kristinn Ö Sverrison, Arvi Yli-Hankala, Morten Hylander Møller
The Scandinavian Society of Anaesthesiology and Intensive Care Medicine Clinical Practice Committee endorses the BMJ Rapid Recommendation clinical practice guideline on atraumatic (pencil-point) vs conventional needles for lumbar puncture. This includes the strong recommendation for the use of atraumatic needles for lumbar puncture in all patients regardless of age or indication.
January 17, 2019: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/30656648/a-1-year-perspective-on-goal-directed-therapy-in-elderly-with-hip-fracture-secondary-outcomes
#18
Erzsebet Bartha, Thomas Davidson, Hans E Berg, Sigridur Kalman
BACKGROUND: We have previously reported inconclusive results from a randomized controlled trial in elderly with hip-fracture comparing intra-operative goal-directed therapy with routine fluid treatment. Now we aimed to describe and compare secondary outcomes at 4 months and 1 year follow-up and to analyze the cost-effectiveness. METHODS: Patients with hip fracture (age ≥70) were randomized for GDT or routine fluid treatment (RFT). The secondary outcomes were long-term survival, complications, number of hospital readmissions, and quality of life (EQ-5D) changes...
January 17, 2019: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/30656639/short-and-long-term-mortality-in-major-non-cardiac-surgical-patients-admitted-to-the-intensive-care-unit
#19
Sarah Ekeloef, Lau C Thygesen, Ismail Gögenur
BACKGROUND: The aim of this register-based cohort study was to characterize patients admitted to the intensive care unit (ICU) following non-cardiac surgery and identify risk factors associated with 30-days, 90-days and 1-year mortality after ICU admission. METHODS: Patients aged 18+ years admitted to the intensive care unit within 30-days of non-cardiac surgery at four Capital Region hospitals in Denmark between January 2005 and December 2014 were included. Patients were identified through the Danish National Patient Register...
January 17, 2019: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/30656637/fentanyl-or-placebo-with-ketamine-for-emergency-department-rapid-sequence-intubation-the-fakt-study-protocol
#20
Ian Ferguson, James Milligan, Alex Buttfield, Shamus Shepherd, Brian Burns, Cliff Reid, Anders Aneman, Ian Harris
BACKGROUND: Some critically ill patients require rapid sequence intubation in the emergency department, and ketamine is one sedative agent employed, due to its relative haemodynamic stability. Tachycardia and hypertension are frequent side effects, and in less stable patients, shock can be unmasked or exacerbated. The use of fentanyl as a co-induction agent may lead to a smoother haemodynamic profile post-induction, which may lead to reduced mortality in this critically ill cohort. This randomised controlled trial aims to compare the effect of administering fentanyl vs placebo in a standardised induction regimen with ketamine and rocuronium on (a) the percentage of patients in each group with a systolic blood pressure outside the range of 100-150 mm Hg within 10 minutes of induction, (b) the laryngoscopic view, and (c) 30-day mortality...
January 17, 2019: Acta Anaesthesiologica Scandinavica
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