Journals Acta Anaesthesiologica Scandin...

Acta Anaesthesiologica Scandinavica
Mikael Barbu, Anders Hjärpe, Andreas Martinsson, Göran Dellgren, Sven-Erik Ricksten, Lukas Lannemyr, Aldina Pivodic, Amar Taha, Anders Jeppsson
BACKGROUND: Cardiopulmonary bypass (CPB) ensures tissue oxygenation during cardiac surgery. New technology allows continuous registration of CPB variables during the operation. The aim of the present investigation was to study the association between CPB management and the risk of postoperative acute kidney injury (AKI). METHODS: This observational study based on prospectively registered data included 2661 coronary artery bypass grafting and/or valve patients operated during 2016-2020...
December 9, 2023: Acta Anaesthesiologica Scandinavica
Eliisa Nissilä, Raili Suojaranta, Marja Hynninen, Sebastian Dahlbacka, Johanna Hästbacka
BACKGROUND: We investigated the prevalence and effects of hazardous alcohol consumption on perioperative complications in cardiac surgery patients. Preoperative hazardous alcohol consumption has been associated with an increased risk of postoperative complications in noncardiac patient populations. METHODS: We retrospectively collected data from the Finnish Intensive Care Consortium database and electronic patient records on all cardiac surgery patients treated in the intensive care units (ICUs) of Helsinki University Hospital (n = 919) during 2017...
November 28, 2023: Acta Anaesthesiologica Scandinavica
Neeliya Anton Joseph, Lone Musaeus Poulsen, Mathias Maagaard, Simon Tholander, Helle Birgitte Scharling Pedersen, Charlotte Georgi-Jensen, Ole Mathiesen, Nina C Andersen-Ranberg
BACKGROUND: Delirium is a clinical condition characterized by an acute change in brain function and is frequently observed in critically ill patients. The condition has been associated with negative outcomes, making it crucial to identify patients who are at risk. Two recent prediction models have been developed to estimate the risk of delirium in intensive care unit (ICU) patients; the prediction model for delirium (PRE-DELIRIC) and the early prediction model for delirium (E-PRE-DELIRIC)...
November 27, 2023: Acta Anaesthesiologica Scandinavica
Liva Thoft Jensen, Lars Lundstrøm, Ana Kowark, Mark Coburn, Jacob Steinmetz
BACKGROUND: Elderly surgical patients have a high risk of postoperative complications. However, patients exhibit considerable diversity in health and functional status; thus, identifying the fragile may be necessary when selecting surgical candidates. We aimed to compare the prevalence of frailty in patients ≥90 years with patients aged 80-89. Second, we assessed the association between frailty and all-cause 30-day mortality. METHODS: We performed a planned secondary analysis of the peri-interventional outcome study in the elderly (POSE), including 9497 patients (≥80 years) undergoing any surgical and nonsurgical procedures in 177 European centres from October 2017 to December 2018...
November 21, 2023: Acta Anaesthesiologica Scandinavica
Tine Sylvest Meyhoff, Anders Granholm, Peter Buhl Hjortrup, Praleene Sivapalan, Theis Lange, Jon Henrik Laake, Maria Cronhjort, Stephan M Jakob, Maurizio Cecconi, Marek Nalos, Marlies Ostermann, Manu L N G Malbrain, Morten Hylander Møller, Anders Perner
BACKGROUND: Albumin administration is suggested in patients with sepsis and septic shock who have received large volumes of crystalloids. Given lack of firm evidence, clinical practice variation may exist. To address this, we investigated if patient characteristics or trial site were associated with albumin use in septic shock. METHODS: We conducted a post-hoc study of the CLASSIC international, randomised clinical trial of fluid volumes in septic shock. Associations between selected baseline variables and trial site with albumin use during ICU stay were assessed in Cox models considering death, ICU discharge, and loss-to-follow-up as competing events...
November 17, 2023: Acta Anaesthesiologica Scandinavica
Christoffer L Madsen, Bonna Leerhøy, Lars N Jørgensen, Christian S Meyhoff, Ahmad Sajadieh, Helena Domínguez
BACKGROUND AND AIM: Scarce data exist on the true incidence of postoperative atrial fibrillation (POAF) after acute abdominal surgery and associated outcomes. The current study aimed to identify the frequencies of clinically recognized POAF and associated complications, along with their risk factors. METHODS: This study was a prospective, single-center cohort study of unselected adult patients referred for acute abdominal surgery during a 3-month period. Through careful review, demographics, comorbidity, and surgical characteristics were prospectively drawn from medical charts...
November 17, 2023: Acta Anaesthesiologica Scandinavica
Sezin Aydemir, Hatice Betul Gemici Karaaslan, Ulviye Mustu, Oguzhan Tin, Ali Ekber Hakalmaz, Rahsan Ozcan, Senol Emre, Pinar Kendigelen, Ayse Cigdem Tutuncu, Ayca Kiykim, Haluk Cokugras
BACKGROUND: There are few studies of perioperative hypersensitivity reactions in children. The diagnosis of perioperative hypersensitivity reactions may be under estimated because it is difficult to recognize the reactions. Anaphylaxis may go unnoticed because of patient unconsciousness. Urticaria may be missed due to sterile drapes. The aim of this study was to prospectively evaluate perioperative hypersensitivity reactions. METHODS: In this prospective study, patients with suspected perioperative hypersensitivity reactions aged 0-18 years who underwent surgery at the Department of Pediatric Surgery, Cerrahpasa Faculty of Medicine, between 2019 and 2021 were investigated...
November 14, 2023: Acta Anaesthesiologica Scandinavica
Iren Sellbrant, Bengt Nellgård, Jon Karlsson, Johanna Albert, Jan G Jakobsson
BACKGROUND: Wrist fracture is one of most common fractures frequently requiring surgical anaesthesia. There is limited information related to the anaesthetic practice and quality including 30-day mortality associated with wrist fracture in Sweden in recent years. AIM: The aim of the present register-based study was to investigate the anaesthesia techniques used and quality indices including 30-day mortality associated with wrist fracture surgery in Sweden during the period 2018-2021...
November 12, 2023: Acta Anaesthesiologica Scandinavica
Jens L Temberg, Sanja Pisljagic, Mathias T Steensbaek, Sina Yousef, Lana Chafranska, Kai H W Lange, Christian Rothe, Anders K Nørskov, Mathias Maagaard, Lars H Lundstrøm
INTRODUCTION: This protocol describes a systematic review and meta-analysis to evaluate the clinical effects of mixing short- and long-acting local anaesthetics in peripheral nerve blocks. Clinicians often combine short- and long-acting local anaesthetics to achieve a briefer onset time. However, this may come with a prize, namely a shorter total duration of the block, which is of clinical importance. OBJECTIVE: This systematic review aims to strengthen the knowledge of the clinical effects associated with this practice...
November 10, 2023: Acta Anaesthesiologica Scandinavica
Thomas C Rollinson, Luke A McDonald, Joleen Rose, Glenn Eastwood, Rahul Costa-Pinto, Lucy Modra, Akinori Maeda, Zoe Bacolas, James Anstey, Samantha Bates, Scott Bradley, Jodi Dumbrell, Craig French, Angaj Ghosh, Kimberley Haines, Tim Haydon, Carol Hodgson, Jennifer Holmes, Nina Leggett, Forbes McGain, Cara Moore, Kathleen Nelson, Jeffrey Presneill, Hannah Rotherham, Simone Said, Meredith Young, Peinan Zhao, Andrew Udy, Anis Chaba, Rinaldo Bellomo, Ary Serpa Neto
BACKGROUND: Prone positioning may improve oxygenation in acute hypoxemic respiratory failure and was widely adopted in COVID-19 patients. However, the magnitude and timing of its peak oxygenation effect remain uncertain with the optimum dosage unknown. Therefore, we aimed to investigate the magnitude of the peak effect of prone positioning on the PaO2 :FiO2 ratio during prone and secondly, the time to peak oxygenation. METHODS: Multi-centre, observational study of invasively ventilated adults with acute hypoxemic respiratory failure secondary to COVID-19 treated with prone positioning...
November 9, 2023: Acta Anaesthesiologica Scandinavica
Anna R Lundén, Pekka Tarkkila
BACKGROUND: We compared analgesia with an ultrasound (US)-guided serratus anterior plane block (SAPB) to thoracic epidural analgesia (EA) with continuous local anaesthetic infusion in patients with unilateral multiple traumatic rib fractures. EA often carries contraindications in patients with multiple rib fractures (MRFs), whereby having alternative effective methods to treat rib fracture pain remains important to patient care. Thus, we hypothesised that both regional anaesthetic techniques would provide effective pain relief...
November 7, 2023: Acta Anaesthesiologica Scandinavica
Sanja Pisljagic, Jens L Temberg, Mathias T Steensbaek, Sina Yousef, Mathias Maagaard, Lana Chafranska, Kai H W Lange, Christian Rothe, Lars H Lundstrøm, Anders K Nørskov
BACKGROUND: Current methods of anaesthesia used for closed reduction of distal radial fractures may be insufficient for pain relief and muscle relaxation, potentially compromising reduction quality and patient satisfaction. Peripheral nerve blocks have already been implemented for surgery of wrist fractures and may provide optimal conditions for closed reduction due to complete motor and sensory blockade of the involved nerves. However, existing literature on peripheral nerve blocks for closed reduction is sparse, and no updated systematic review or meta-analysis exists...
November 6, 2023: Acta Anaesthesiologica Scandinavica
Roberta Sudy, Domitille Dereu, Na Lin, Isabelle Pichon, Ferenc Petak, Walid Habre, Gergely Albu
BACKGROUND: Lung volume loss is a major risk factor for postoperative respiratory complications after general anaesthesia and mechanical ventilation. We hypothesise that spontaneous breathing without pressure support may enhance the risk for atelectasis development. Therefore, we aimed at characterising whether pressure support prevents changes in lung function in patients breathing spontaneously through laryngeal mask airway. METHODS: In this randomised controlled trial, adult female patients scheduled for elective gynaecological surgery in lithotomy position were randomly assigned to the continuous spontaneous breathing group (CSB, n = 20) or to the pressure support ventilation group (PSV, n = 20) in a tertiary university hospital...
November 3, 2023: Acta Anaesthesiologica Scandinavica
Anne Louise de Barros Garioud, Lars Peter Kloster Andersen, Aksel Karl Georg Jensen, Hien Quoc Do, Janus Christian Jakobsen, Lars Broksø Holst, Lars Simon Rasmussen, Arash Afshari
BACKGROUND: Emergence agitation and delirium in children remain a common clinical challenge in the post-anesthetic care unit. Preoperative oral melatonin has been suggested as an effective preventive drug with a favorable safety profile. The oral bioavailability of melatonin, however, is low. Therefore, the MELA-PAED trial aims to investigate the efficacy and safety of intraoperative intravenous melatonin for the prevention of emergence agitation in pediatric surgical patients. METHODS: MELA-PAED is a randomized, double-blind, parallel two-arm, multi-center, superiority trial comparing intravenous melatonin with placebo...
October 30, 2023: Acta Anaesthesiologica Scandinavica
Steven A Frost, Kathleen Brennan, David Sanchez, Joan Lynch, Sonja Hedges, Yu Chin Hou, Masar El Sayfe, Sharon-Ann Shunker, Tony Bogdanovski, Leanne Hunt, Evan Alexandrou, Kaye Rolls, Danielle Ni Chroinin, Anders Aneman
BACKGROUND: Delirium is an acute disorder of attention and cognition with an incidence of up to 70% in the adult intensive care setting. Due to the association with significantly increased morbidity and mortality, it is important to identify who is at the greatest risk of an acute episode of delirium while being cared for in the intensive care. The objective of this study was to determine the ability of the cumulative deficit frailty index and clinical frailty scale to predict an acute episode of delirium among adults admitted to the intensive care...
October 30, 2023: Acta Anaesthesiologica Scandinavica
Anders C Feyling, Patrick D Kamalo, Terje Hanche-Olsen, Singatiya S Chikumbanje, Aina S Zsidek, Erica Ponzi, Johan Raeder
PURPOSE: The objective of this study was to compare the efficacy of a low-cost heat-preserving method in preventing intraoperative hypothermia with that of forced-air warming in a resource-limited setting. METHODS: In this randomized controlled non-inferiority trial, we recruited children younger than 12 years scheduled for cranial neurosurgery in a large East-African hospital. Patients were block-randomized by age to intraoperative warming measures using Hibler's method (intervention) or warm air (comparator)...
October 26, 2023: Acta Anaesthesiologica Scandinavica
Marie Warrer Munch, Anders Granholm, Jan Maláska, Jan Stašek, Pablo O Rodriguez, Tyler Pitre, Rebecca Wilson, Jelena Savović, Bram Rochwerg, Adam Svobodnik, Milan Kratochvíl, Manuel Taboada, Vivekanand Jha, Bharath Kumar Tirupakuzhi Vijayaraghavan, Sheila Nainan Myatra, Balasubramanian Venkatesh, Anders Perner, Morten Hylander Møller
BACKGROUND: The optimal dose of dexamethasone for severe/critical COVID-19 is uncertain. We compared higher versus standard doses of dexamethasone in adults with COVID-19 and hypoxia. METHODS: We searched PubMed and trial registers until 23 June 2023 for randomised clinical trials comparing higher (>6 mg) versus standard doses (6 mg) of dexamethasone in adults with COVID-19 and hypoxia. The primary outcome was mortality at 1 month. Secondary outcomes were mortality closest to 90 days; days alive without life support; and the occurrence of serious adverse events/reactions (SAEs/SARs) closest to 1 month...
October 26, 2023: Acta Anaesthesiologica Scandinavica
Pedro Hilton de Andrade Filho, Joao Manoel Silva
No abstract text is available yet for this article.
October 25, 2023: Acta Anaesthesiologica Scandinavica
Christine N Svendsen, Gine L Glargaard, Lars H Lundstrøm, Charlotte V Rosenstock, Anne C Haug, Arash Afshari, Rasmus Hesselfeldt, Camilla Strøm
BACKGROUND: Few clinical studies investigate technical skill performance in experienced clinicians. METHODS: We undertook a prospective observational study evaluating procedural skill competence in consultant anaesthetists who performed flexible bronchoscopic intubation (FBI) under continuous ventilation through a second-generation supraglottic airway device (SAD). Airway management was recorded on video and performance evaluated independently by three external assessors...
October 25, 2023: Acta Anaesthesiologica Scandinavica
Stine Fjendbo Galili, Lone Nikolajsen, Bodil Hammer Bech, Hans Kirkegaard, Jette Ahrensberg
BACKGROUND: Patients with a daily use of opioids have a higher risk of insufficient pain treatment during hospitalization than other patients. This study aimed to examine whether as-needed opioid doses (PRN) were adequately adjusted when patients were admitted to the emergency department (ED) with pain. METHODS: Patients, with a daily use of opioids, who received PRN opioid within the first 3 h after admission at the ED at Aarhus University Hospital, Denmark, were prospectively included from February 2021 to June 2021...
October 25, 2023: Acta Anaesthesiologica Scandinavica
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