JOURNAL ARTICLE
REVIEW
Add like
Add dislike
Add to saved papers

Pseudomembranous colitis in children.

This review presents the microbiology, management and prevention of pseudomembranous colitis (PMC) in children. PMC is commonly associated with prior antibiotic exposure and hospitalization. It is caused almost exclusively by toxins produced by Clostridium difficile. The clinical spectrum of this disease may range from a mild, non-specific diarrhea to severe colitis with toxic megacolon, perforation, and death. PMC may affect all age groups, although a lower incidence has been noted in children. Ampicillin, amoxicillin, the second- and third-generation cephalosporins and clindamycin are the drugs most frequently associated with development of PMC, although nearly all antimicrobials have been implicated as causes of diarrhea and colitis. Discontinuation of antibiotics and supportive therapy usually lead to resolution of this disorder. Administration of oral vancomycin or other therapeutic regimens may be needed.

Full text links

We have located links that may give you full text access.
Can't access the paper?
Try logging in through your university/institutional subscription. For a smoother one-click institutional access experience, please use our mobile app.

For the best experience, use the Read mobile app

Mobile app image

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

By using this service, you agree to our terms of use and privacy policy.

Your Privacy Choices Toggle icon

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app