Ruibin Zhang, Guihua Jiang, Junzhang Tian, Yingwei Qiu, Xue Wen, Andrew Zalesky, Meng Li, Xiaofen Ma, Junjing Wang, Shumei Li, Tianyue Wang, Changhong Li, Ruiwang Huang
Neuroimaging studies suggested that drug addiction is linked to abnormal brain functional connectivity. However, little is known about the alteration of brain white matter (WM) connectivity in addictive drug users and nearly no study has been performed to examine the alterations of brain WM connectivity in heroin-dependent individuals (HDIs). Diffusion tensor imaging (DTI) offers a comprehensive technique to map the whole brain WM connectivity in vivo. In this study, we acquired DTI datasets from 20 HDIs and 18 healthy controls and constructed their brain WM structural networks using a deterministic fibre tracking approach...
May 2016: Addiction Biology