Nhat Hung Benjamin Lam, Kiera Liblik
1. In this randomized controlled trial, among patients with recurrent kidney stones, hydrochlorothiazide did not alter the risk of symptomatic or radiographic stone recurrence.
2. Hydrochlorothiazide was associated with an increased risk of adverse events as compared to placebo.
Evidence Rating Level: 1 (Excellent)
Study Rundown: Kidney stones are a common medical condition. In many patients, these stones can be recurrent, resulting in significant distress, impaired quality of life, and healthcare burden. Calcium oxalate and calcium phosphate comprise the most common forms of kidney stones, and hypercalciuria is the most common metabolic disturbance predisposing patients to kidney stones...
March 22, 2023: 2 Minute Medicine