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Shrewsbury and Telford Hospital NHS Trust staff publications
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Cervicofacial infection (CFI) is a frequently encountered presentation to Oral and Maxillofacial Departments (OMFS). The United Kingdom has recently seen cessation of all routine community dental treatment due to the Coronavirus (COVID-19) pandemic and consequently an initial modification of treatment received in secondary care. Subsequent airway difficulties and the need for level 2 High Dependency Unit (HDU) or level 3 Intensive Care Unit (ICU) is a concern to surgeons and anaesthetists alike. The availability of skilled staff and appropriate facilities can be variable...
November 2022: British Journal of Oral & Maxillofacial Surgery
Matti Jubouri, Ravi Patel, Sven Zcp Tan, Mohammed Al-Tawil, Mohamad Bashir, Damian M Bailey, Ian M Williams
BACKGROUND: Type B aortic dissection (TBAD) occurs due to an entry tear in the intimal layer of the aorta distal to the origin of the left subclavian artery where blood enters the newly formed false lumen (FL) and extends distally or proximally to form a dissection over an indeterminate length of the aorta which, over time, may eventually rupture. Thoracic endovascular aortic repair (TEVAR) aims to seal off the entry tear proximally with the stent-graft, occluding the origin of the dissection and excluding the FL...
August 2023: Annals of Vascular Surgery
Rehab Haider, Zofirah Isiaka, Shabeena Zeb, Mohit Inani, Joshua Nimrod, Gordon Wood
No abstract text is available yet for this article.
July 2022: Future Healthcare Journal
Mohit Inani, Nishita Padmanabhan, Sayed Kazi, Katherine Willmer, May Yan, Gordon Wood, Muhammad Asad, Aung Thant
No abstract text is available yet for this article.
July 2022: Future Healthcare Journal
Shabeena Zeb, Amol Sagdeo, Roshan Amarasena
No abstract text is available yet for this article.
July 2022: Clinical Medicine: Journal of the Royal College of Physicians of London
Sadie Bennett, Martin Stout, Thomas E Ingram, Keith Pearce, Timothy Griffiths, Simon Duckett, Grant Heatlie, Patrick Thompson, Judith Tweedie, Jo Sopala, Sarah Ritzmann, Kelly Victor, Judith Skipper, Benoy N Shah, Shaun Robinson, Andrew Potter, Daniel X Augustine, Claire L Colebourn
Transthoracic echocardiography (TTE) is widely utilised within many aspects of clinical practice, as such the demand placed on echocardiography services is ever increasing. In an attempt to provide incremental value for patients and standardise patient care, the British Society of Echocardiography in collaboration with the British Heart Valve Society have devised updated guidance for the indications and triaging of adult TTE requests for TTE services to implement into clinical practice.
July 13, 2022: Echo Research and Practice
Blossom Lake, Sarah Damery, Kate Jolly
BACKGROUND: Elevated body mass index (BMI) in breast cancer survivors (BCS) is associated with cancer recurrence and poorer treatment response. Guidelines recommend 5%-10% weight loss for overweight or obese BCS. OBJECTIVES: To assess effectiveness of lifestyle interventions for female BCS on weight loss, BMI, body composition, health-related quality of life (HRQoL), physical functioning, psychosocial measures, biomarkers. DESIGN: Systematic review of reviews and meta-analyses...
October 7, 2022: BMJ Open
Rammohan R, Luke Nugent, Sarang Kasture, Muthu Ganapathi
INTRODUCTION: Use of patient specific instrumentation (PSI) for performing total knee arthroplasty (TKA) has been shown to improve component positioning but there is dearth of evidence regarding clinical outcomes. The aim of our study was to report patient satisfaction and functional outcome scores of patients who underwent PSI TKAs at minimum 5 year follow up. METHODS: This is a retrospective study of a prospectively collected data of patients who underwent PSI TKAs between January 2012 and October 2015 under a single surgeon...
June 2023: Archives of Orthopaedic and Trauma Surgery
Khalid A Al-Hashimi, Umar N Said
The pathogenicity of Mycobacterium tuberculosis (M. tuberculosis) causes it to most commonly manifest within the respiratory system (pulmonary tuberculosis); however, 15% of cases undergo extra-pulmonary spread to various organs. Genitourinary tuberculosis (GUTB) is a rare form of tuberculosis infection which has a propensity to affect the genitourinary tract, primarily affecting the kidneys, epididymis, seminal vesicles and prostate; however, 0.5% of cases result in infection of the testicles. This may present unilaterally or bilaterally with varying atypical presentations, thus misleading physicians in diagnosis...
October 2021: Curēus
Shima Chundoo, Prady Naredla, Suraj Thomas
Head and neck cancer can leave patients with significant defects requiring major reconstruction. The scapula free flap remains a relatively underused flap choice. This article examines the novel use of a custom guide for a scapula free flap in mandibular reconstruction following resection. A case file was created involving a consultant surgeon, KLS advisor, and technical team based in Belgium. A computed tomography scan of the mandible was sent electronically to render a 3-dimensional model. Custom cutting guides for resection and scapula graft harvest were fabricated...
October 1, 2022: Journal of Craniofacial Surgery
Yew Fung Chin, Naing Lynn
Cryotherapy is one of the recognised ablative modalities for both primary and salvage therapy for prostate cancer. It presents an alternative, less invasive treatment for an organ-confined disease, improved preservation of surrounding tissue and a more suitable option for patients who are unfit for radical prostatectomy. Nevertheless, the currently available literature is relatively too scarce to provide definite conclusions regarding the treatment outcomes in cryotherapy. The present study aimed to review current oncological and survival outcomes in cryotherapy for primary and recurrent prostate cancer...
June 2022: Curēus
E Mullins, A Perry, J Banerjee, J Townson, D Grozeva, R Milton, N Kirby, R Playle, T Bourne, C Lees
OBJECTIVE: To assess perinatal outcomes for pregnancies affected by suspected or confirmed SARS-CoV-2 infection. METHODS: Prospective, web-based registry. Pregnant women were invited to participate if they had suspected or confirmed SARS-CoV-2 infection between 1st January 2020 and 31st March 2021 to assess the impact of infection on maternal and perinatal outcomes including miscarriage, stillbirth, fetal growth restriction, pre-term birth and transmission to the infant...
September 2022: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Elin Larsson, Annelie Brorsson, Malin Carling, Christer Johansson, Michael R Carmont, Katarina Nilsson Helander
INTRODUCTION: The incidence of Achilles tendon ruptures (ATR) has increased over the past few decades. Treatment may be individualised based upon multiple factors including age, pre-injury activity level and the separation of the ruptured tendon ends. Several studies indicate that women may have a poorer self-reported and clinical outcome compared with men, but the number of women in these studies is often small due to the different incidence of ATR between the genders. AIMS: The primary aim of this study was to evaluate whether there is a difference in self-reported outcome after an acute ATR between women and men at one to five years following injury...
October 13, 2022: BMC Musculoskeletal Disorders
Victor Lu, Maria Tennyson, Andrew Zhou, Ravi Patel, Mary D Fortune, Azeem Thahir, Matija Krkovic
INTRODUCTION: Fragility ankle fractures are traditionally managed conservatively or with open reduction internal fixation. Tibiotalocalcaneal (TTC) nailing is an alternative option for the geriatric patient. This meta-analysis provides the most detailed analysis of TTC nailing for fragility ankle fractures. METHODS: A systematic search was performed on MEDLINE, EMBASE, Cochrane Library, and Web of Science, identifying 14 studies for inclusion. Studies including patients with a fragility ankle fracture, defined according to NICE guidelines as a low-energy fracture obtained following a fall from standing height or less, that were treated with TTC nail were included...
September 19, 2022: EFORT Open Reviews
Harrypal Panesar, Ravi Patel, Harjit Dhaliwal
Uterine rupture is a rare life-threatening complication. It can occur in all 3 trimesters with the first and the second being a rarity. It mainly occurs in the third trimester or during labor in a previously scarred uterus. It is rare in an unscarred uterus. The risk fold is further enhanced by the induction and augmentation with prostaglandins and oxytocin. The clinical diagnosis at this early gestation can be a dilemma to the attending physician as in this case. (1) The patient was a holidaymaker with no documented evidence of a dating scan to suggest any evidence of an ovarian/placental pathology at that stage...
November 2022: Radiology Case Reports
H N Humphrey, A Diodato, J-C Isner, E Walker, J Lacy-Colson, B Nedjai, I R Daniels
BACKGROUND: The ORI-EGI-02 study was designed to test the hypothesis that rectal mucus collected using a novel rectal sampling device (OriCol™), contains sufficient human deoxyribonucleic acid (DNA) of the required quality for Next Generation Sequencing (NGS), for colorectal disease genetic signature discovery. METHODS: Using National Institute for Health and Care Research methodology, an internal pilot study was performed in January 2020-May 2021, at four sites in the United Kingdom, to assess the process of recruitment, consent, specimen acquisition and viability for analysis...
March 2023: Techniques in Coloproctology
Elin Larsson, Katarina Nilsson Helander, Lotta Falkheden Henning, Mervi Heiskanen, Michael R Carmont, Karin Grävare Silbernagel, Annelie Brorsson
PURPOSE: The aim of this study was to investigate how the Achilles tendon resting angle (ATRA), an indirect measurement of tendon elongation, correlates with ultrasonography (US) measurements of the Achilles tendon length 6 and 12 months after an acute ATR and relates to other clinical outcome measurements such as heel-rise height, jumping ability and patient-reported outcome measurements (PROMs). METHODS: Patients were included following acute Achilles tendon rupture (ATR)...
September 10, 2022: Knee Surgery, Sports Traumatology, Arthroscopy
David M McGoldrick, Aghiad Yassin Alsabbagh, Moinuddin Shaikh, Laura Pettit, Sunil K Bhatia
INTRODUCTION AND AIM: Sarcopenia is increasingly recognised as a poor prognostic factor in older patients undergoing cancer treatment. Recently, masseter muscle cross sectional area (MMCSA) has been shown to accurately identify sarcopenic patients. We aimed to apply this novel technique to a head and neck cohort to identify any potential relationship with survival. MATERIALS AND METHODS: A retrospective review was undertaken of patients over 65 years, diagnosed with squamous cell carcinoma of the head and neck and treated with curative intent in our unit between October 2009 and October 2017...
August 5, 2021: British Journal of Oral & Maxillofacial Surgery
Dimitrios Papoutsis
No abstract text is available yet for this article.
January 2023: BJOG: An International Journal of Obstetrics and Gynaecology
Neil Chanchlani, Simeng Lin, Marcus K Auth, Chai Leng Lee, Helena Robbins, Shi Looi, Senthil V Murugesan, Tom Riley, Cathryn Preston, Sophie Stephenson, Wendy Cardozo, Sunil A Sonwalkar, Mohammed Allah-Ditta, Lynne Mansfield, Dharmaraj Durai, Mark Baker, Ian London, Emily London, Sanjay Gupta, Alex Di Mambro, Aisling Murphy, Edward Gaynor, Kelsey D J Jones, Andrew Claridge, Shaji Sebastian, Sankaranarayanan Ramachandran, Christian P Selinger, Simon P Borg-Bartolo, Paul Knight, Michael B Sprakes, Julie Burton, Patricia Kane, Stephanie Lupton, Aimee Fletcher, Daniel R Gaya, Roghan Colbert, John Paul Seenan, Jonathan MacDonald, Lucy Lynch, Iain McLachlan, Stephanie Shields, Richard Hansen, Lisa Gervais, Mwansa Jere, Muhammad Akhtar, Karen Black, Paul Henderson, Richard K Russell, Charlie W Lees, Lauranne A A P Derikx, Melanie Lockett, Frederica Betteridge, Aminda De Silva, Arif Hussenbux, John Beckly, Oliver Bendall, James W Hart, Amanda Thomas, Ben Hamilton, Claire Gordon, Desmond Chee, Timothy J McDonald, Rachel Nice, Marian Parkinson, Helen Gardner-Thorpe, Jeff R Butterworth, Asima Javed, Sarah Al-Shakhshir, Rekha Yadagiri, Sebrene Maher, Richard C G Pollok, Tze Ng, Priscilla Appiahene, Fiona Donovan, James Lok, Rajiv Chandy, Reema Jagdish, Daniyal Baig, Zahid Mahmood, Liane Marsh, Allison Moss, Amin Abdulgader, Angus Kitchin, Gareth J Walker, Becky George, Yuen-Hui Lim, James Gulliver, Stuart Bloom, Holly Theaker, Sean Carlson, J R Fraser Cummings, Robert Livingstone, Amanda Beale, Josiah O Carter, Andrew Bell, Archibald Coulter, Jonathon Snook, Helen Stone, Nicholas A Kennedy, James R Goodhand, Tariq Ahmad
BACKGROUND: Anti-drug antibodies are associated with treatment failure to anti-TNF agents in patients with inflammatory bowel disease (IBD). AIM: To assess whether immunogenicity to a patient's first anti-TNF agent would be associated with immunogenicity to the second, irrespective of drug sequence METHODS: We conducted a UK-wide, multicentre, retrospective cohort study to report rates of immunogenicity and treatment failure of second anti-TNF therapies in 1058 patients with IBD who underwent therapeutic drug monitoring for both infliximab and adalimumab...
October 2022: Alimentary Pharmacology & Therapeutics
2023-02-16 15:44:28
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