Marie-Léa Gauci, Cynthia Aristei, Jurgen C Becker, Astrid Blom, Veronique Bataille, Brigitte Dreno, Veronique Del Marmol, Ana M Forsea, Maria C Fargnoli, Jean-Jacques Grob, Fabio Gomes, Axel Hauschild, Christoph Hoeller, Catherine Harwood, Nicole Kelleners-Smeets, Roland Kaufmann, Aimilios Lallas, Josep Malvehy, David Moreno-Ramirez, Ketty Peris, Giovanni Pellacani, Philippe Saiag, Alexander J Stratigos, Ricardo Vieira, Iris Zalaudek, Alexander C J van Akkooi, Paul Lorigan, Claus Garbe, Céleste Lebbé
Merkel cell carcinoma (MCC) is a rare skin cancer, accounting for less than 1% of all cutaneous malignancies. It is found predominantly in white populations and risk factors include advanced age, ultraviolet exposure, male sex, immunosuppression, such as AIDS/HIV infection, haematological malignancies or solid organ transplantation, and Merkel cell polyomavirus infection. MCC is an aggressive tumour with 26% of cases presenting lymph node involvement at diagnosis and 8% with distant metastases. Five-year overall survival rates range between 48% and 63%...
August 2022: European Journal of Cancer