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Breaking Research on COVID-19 Pandemic

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161 papers 1000+ followers Articles and resources related to the Coronavirus outbreak
https://read.qxmd.com/read/32202721/the-toughest-triage-allocating-ventilators-in-a-pandemic
#1
Robert D Truog, Christine Mitchell, George Q Daley
No abstract text is available yet for this article.
March 23, 2020: New England Journal of Medicine
https://read.qxmd.com/read/32220207/undocumented-u-s-immigrants-and-covid-19
#2
Kathleen R Page, Maya Venkataramani, Chris Beyrer, Sarah Polk
No abstract text is available yet for this article.
March 27, 2020: New England Journal of Medicine
https://read.qxmd.com/read/32220208/epidemiology-of-covid-19-in-a-long-term-care-facility-in-king-county-washington
#3
Temet M McMichael, Dustin W Currie, Shauna Clark, Sargis Pogosjans, Meagan Kay, Noah G Schwartz, James Lewis, Atar Baer, Vance Kawakami, Margaret D Lukoff, Jessica Ferro, Claire Brostrom-Smith, Thomas D Rea, Michael R Sayre, Francis X Riedo, Denny Russell, Brian Hiatt, Patricia Montgomery, Agam K Rao, Eric J Chow, Farrell Tobolowsky, Michael J Hughes, Ana C Bardossy, Lisa P Oakley, Jesica R Jacobs, Nimalie D Stone, Sujan C Reddy, John A Jernigan, Margaret A Honein, Thomas A Clark, Jeffrey S Duchin
BACKGROUND: Long-term care facilities are high-risk settings for severe outcomes from outbreaks of Covid-19, owing to both the advanced age and frequent chronic underlying health conditions of the residents and the movement of health care personnel among facilities in a region. METHODS: After identification on February 28, 2020, of a confirmed case of Covid-19 in a skilled nursing facility in King County, Washington, Public Health-Seattle and King County, aided by the Centers for Disease Control and Prevention, launched a case investigation, contact tracing, quarantine of exposed persons, isolation of confirmed and suspected cases, and on-site enhancement of infection prevention and control...
March 27, 2020: New England Journal of Medicine
https://read.qxmd.com/read/32222181/covid-19-learning-from-experience
#4
EDITORIAL
The Lancet
No abstract text is available yet for this article.
March 28, 2020: Lancet
https://read.qxmd.com/read/32222587/-preparing-for-the-covid-19-pandemic-our-experience-in-new-york
#5
EDITORIAL
Zubair Hasan, Mangala Narasimhan
No abstract text is available yet for this article.
March 25, 2020: Chest
https://read.qxmd.com/read/32222812/surviving-sepsis-campaign-guidelines-on-the-management-of-critically-ill-adults-with-coronavirus-disease-2019-covid-19
#6
Waleed Alhazzani, Morten Hylander Møller, Yaseen M Arabi, Mark Loeb, Michelle Ng Gong, Eddy Fan, Simon Oczkowski, Mitchell M Levy, Lennie Derde, Amy Dzierba, Bin Du, Michael Aboodi, Hannah Wunsch, Maurizio Cecconi, Younsuck Koh, Daniel S Chertow, Kathryn Maitland, Fayez Alshamsi, Emilie Belley-Cote, Massimiliano Greco, Matthew Laundy, Jill S Morgan, Jozef Kesecioglu, Allison McGeer, Leonard Mermel, Manoj J Mammen, Paul E Alexander, Amy Arrington, John E Centofanti, Giuseppe Citerio, Bandar Baw, Ziad A Memish, Naomi Hammond, Frederick G Hayden, Laura Evans, Andrew Rhodes
BACKGROUND: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness, Coronavirus Disease 2019 (COVID-19), affecting thousands of people around the world. Urgent guidance for clinicians caring for the sickest of these patients is needed. METHODS: We formed a panel of 36 experts from 12 countries. All panel members completed the World Health Organization conflict of interest disclosure form. The panel proposed 53 questions that are relevant to the management of COVID-19 in the ICU...
March 28, 2020: Intensive Care Medicine
https://read.qxmd.com/read/32223068/precautionary-measures-needed-for-ophthalmologists-during-pandemic-of-the-coronavirus-disease-2019-covid-19
#7
EDITORIAL
Kelvin H Wan, Suber S Huang, Alvin Young, Dennis Shun Chiu Lam
The novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged in December 2019 in Wuhan, China has spread to over 113 countries with 118,326 infected and 4,292 died as of 11 March 2020 and the World Health Organization (WHO) has just announced COVID-19 a global pandemic. A person under investigation (PUI) for COVID-19 is less likely to present initially to the ophthalmologists compared to emergency care or internal medicine physicians...
March 29, 2020: Acta Ophthalmologica
https://read.qxmd.com/read/32220826/covid-19-hospitals-brace-for-disaster-as-us-surpasses-china-in-number-of-cases
#8
Owen Dyer
No abstract text is available yet for this article.
March 27, 2020: BMJ: British Medical Journal
https://read.qxmd.com/read/32220865/non-steroidal-anti-inflammatory-drugs-and-covid-19
#9
EDITORIAL
Paul Little
No abstract text is available yet for this article.
March 27, 2020: BMJ: British Medical Journal
https://read.qxmd.com/read/32221512/covid-19-research-in-brief-20-march-to-27-march-2020
#10
Thiago Carvalho
No abstract text is available yet for this article.
March 27, 2020: Nature Medicine
https://read.qxmd.com/read/32221515/spotlight-on-jails-covid-19-mitigation-policies-needed-now
#11
Alysse G Wurcel, Emily Dauria, Nicholas Zaller, Ank Nijhawan, Curt Beckwith, Kathryn Nowotny, Lauren Brinkley-Rubinstein
No abstract text is available yet for this article.
March 28, 2020: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://read.qxmd.com/read/32221519/antibody-responses-to-sars-cov-2-in-patients-of-novel-coronavirus-disease-2019
#12
Juanjuan Zhao, Quan Yuan, Haiyan Wang, Wei Liu, Xuejiao Liao, Yingying Su, Xin Wang, Jing Yuan, Tingdong Li, Jinxiu Li, Shen Qian, Congming Hong, Fuxiang Wang, Yingxia Liu, Zhaoqin Wang, Qing He, Zhiyong Li, Bin He, Tianying Zhang, Yang Fu, Shengxiang Ge, Lei Liu, Jun Zhang, Ningshao Xia, Zheng Zhang
BACKGROUND: The novel coronavirus SARS-CoV-2 is a newly emerging virus. The antibody response in infected patient remains largely unknown, and the clinical values of antibody testing have not been fully demonstrated. METHODS: A total of 173 patients with SARS-CoV-2 infection were enrolled. Their serial plasma samples (n=535) collected during the hospitalization were tested for total antibodies (Ab), IgM and IgG against SARS-CoV-2. The dynamics of antibodies with the disease progress was analyzed...
March 28, 2020: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://read.qxmd.com/read/32221523/quantitative-detection-and-viral-load-analysis-of-sars-cov-2-in-infected-patients
#13
Fengting Yu, Liting Yan, Nan Wang, Siyuan Yang, Linghang Wang, Yunxia Tang, Guiju Gao, Sa Wang, Chengjie Ma, Ruming Xie, Fang Wang, Chianru Tan, Lingxiang Zhu, Yong Guo, Fujie Zhang
BACKGROUND: Coronavirus disease 2019 (COVID-19) has become a public health emergency. The widely used reverse transcription PCR (RT-PCR) method has limitations for clinical diagnosis and treatment. METHODS: A total of 323 samples from 76 COVID-19 confirmed patients were analyzed by droplet digital PCR (ddPCR) and RT-PCR based two target genes (ORF1ab and N). Nasal swabs, throat swabs, sputum, blood, and urine were collected. Clinical and imaging data were obtained for clinical staging...
March 28, 2020: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://read.qxmd.com/read/32221579/sourcing-personal-protective-equipment-during-the-covid-19-pandemic
#14
Edward Livingston, Angel Desai, Michael Berkwits
No abstract text is available yet for this article.
March 28, 2020: JAMA: the Journal of the American Medical Association
https://read.qxmd.com/read/32221964/use-of-in-situ-simulation-to-evaluate-the-operational-readiness-of-a-high-consequence-infectious-disease-intensive-care-unit
#15
T E Fregene, P Nadarajah, J F Buckley, S Bigham, V Nangalia
On 30 January 2020, the World Health Organization (WHO) declared that the outbreak of a coronavirus disease-2019 (COVID-19) was a public health emergency of international concern. The WHO guidance states that patients with (COVID-19) should be managed by staff wearing appropriate personal protective equipment; however, working whilst wearing personal protective equipment is unfamiliar to many healthcare professionals. We ran high-fidelity, in-situ simulation of high-risk procedures on patients with COVID-19 in a negative-pressure side room on our intensive care unit (ICU)...
March 27, 2020: Anaesthesia
https://read.qxmd.com/read/32186952/covid-19-an-emerging-coronavirus-infection-advances-and-prospects-in-designing-and-developing-vaccines-immunotherapeutics-and-therapeutics
#16
Kuldeep Dhama, Khan Sharun, Ruchi Tiwari, Maryam Dadar, Yashpal Singh Malik, Karam Pal Singh, Wanpen Chaicumpa
The novel coronavirus infection (COVID-19 or Coronavirus disease 2019) that emerged from Wuhan, Hubei province of China has spread to many countries worldwide. Efforts have been made to develop vaccines against human coronavirus (CoV) infections such as MERS and SARS in the past decades. However, to date, no licensed antiviral treatment or vaccine exists for MERS and SARS. Most of the efforts for developing CoV vaccines and drugs target the spike glycoprotein or S protein, the major inducer of neutralizing antibodies...
March 18, 2020: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/32211755/epidemiological-and-clinical-predictors-of-covid-19
#17
Yinxiaohe Sun, Vanessa Koh, Kalisvar Marimuthu, Oon Tek Ng, Barnaby Young, Shawn Vasoo, Monica Chan, Vernon J M Lee, Partha P De, Timothy Barkham, Raymond T P Lin, Alex R Cook, Yee Sin Leo
BACKGROUND: Rapid identification of COVID-19 cases, which is crucial to outbreak containment efforts, is challenging due to the lack of pathognomonic symptoms and in settings with limited capacity for specialized nucleic acid-based reverse transcription polymerase chain reaction (PCR) testing. METHODS: This retrospective case-control study involves subjects (7 to 98 years) presenting at the designated national outbreak screening centre and tertiary care hospital in Singapore for SARS-CoV-2 testing from January 26 to February 16, 2020...
March 25, 2020: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://read.qxmd.com/read/32211771/could-chloroquine-hydroxychloroquine-be-harmful-in-coronavirus-disease-2019-covid-19-treatment
#18
Maurizio Guastalegname, Alfredo Vallone
No abstract text is available yet for this article.
March 24, 2020: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://read.qxmd.com/read/32211831/postacute-care-preparedness-for-covid-19-thinking-ahead
#19
David C Grabowski, Karen E Joynt Maddox
No abstract text is available yet for this article.
March 25, 2020: JAMA: the Journal of the American Medical Association
https://read.qxmd.com/read/32212386/coronavirus-disease-2019-in-geriatrics-and-long-term-care-the-abcds-of-covid-19
#20
Heather D'Adamo, Thomas Yoshikawa, Joseph G Ouslander
The pandemic of coronavirus disease of 2019 (COVID-19) has global impact unseen since the 1918 worldwide influenza epidemic. All aspects of life have changed dramatically for now. The group most susceptible to COVID-19 are older adults and those with chronic underlying chronic medical disorders. The population residing in long-term care facilities generally are those who are both old and suffering from multiple comorbidities. In this article we provide information, insights, and recommended approaches to COVID-19 in the long-term facility setting...
March 25, 2020: Journal of the American Geriatrics Society
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